VOHQ 400 Tablet 10's

Introduction About VOHQ 400 TABLET

VOHQ 400 TABLET contains Hydroxychloroquine which belongs to the group of
medicines called Antimalarials or Disease-Modifying Anti-Rheumatic Drugs
(DMARDs). It is used to manage malarial infection. Malaria is a parasitic
infection caused by the plasmodium parasite, which spreads in blood by the bite
of an infectious mosquito. It is characterized by symptoms such as fever,
chills, sweating, headache, nausea, vomiting, body pain and general discomfort.
It is also used to manage rheumatoid arthritis, discoid and systemic lupus
erythematosus in adults and manages juvenile idiopathic arthritis in children.
Also, it is used to manage skin problems (which are sensitive to sunlight). It
is used in patients with type 2 diabetes mellitus as an adjunct to diet and
exercise to improve glycemic control of patients on metformin and sulfonylurea
combination.

Rheumatoid arthritis, discoid and systemic lupus erythematosus is an
inflammatory autoimmune condition in which the immune system attacks its own
body cells. It is generalized by symptoms such as painful swelling, stiffness,
swelling, tenderness or weakness of bone joints, weakness, fever, skin rashes
and anemia. VOHQ 400 TABLET is not recommended for use in patients with
maculopathy or retinal disorder of the eye and changes in eye color, etc. Your
doctor may recommend you to take relevant tests to understand your existing
condition.

Before taking VOHQ 400 TABLET inform your doctor if you have heart disease,
psoriasis or porphyria, blood disorders (such as aplastic anemia,
agranulocytosis, leukopenia or thrombocytopenia) glucose-6-phosphate
dehydrogenase (G6PD) deficiency, psychological disorders, abnormal blood sugar
levels. VOHQ 400 TABLET should be used with caution in pregnant and
breastfeeding women only if advised by the doctor. VOHQ 400 TABLET should be
used with caution in children and elderly patients (aged 65 years and above).
The most common side effects of taking VOHQ 400 TABLET are nausea, vomiting,
loose stools, stomach pain, headache, loss of appetite and skin rashes. Consult
your doctor if any of the side effects worsen.

Uses Of VOHQ 400 TABLET

• Manages malarial infection in adults and children
• Manage rheumatoid arthritis, discoid and systemic lupus erythematosus
• Manage skin problems (which are sensitive to sunlight)
• Manage juvenile idiopathic arthritis
• Used in patients with type 2 diabetes mellitus to improve glycemic control

How VOHQ 400 TABLET Works

VOHQ 400 TABLET works by increasing the potential of Hydrogen (pH) in a cell
which disrupts the survival of infectious org
release of inflammatory enzymes. As a result, VOHQ 400 TABLET manages malarial
infections in children and adults, it also manages rheumatoid arthritis and
lupus erythematosus in adults.

How to use VOHQ 400 TABLET

Always take VOHQ 400 TABLET as directed by your physician. Swallow the medicine
as a whole with a glass of water and do not crush or chew the medicine. Your
doctor will decide the correct dose, duration and frequency for you depending
upon your age, body weight and disease conditions.

Side Effects Of VOHQ 400 TABLET

Common

• Nausea
• vomiting
• Diarrhea
• Stomach pain
• Headache
• Loss of appetite
• Skin rashes or itching
• Mood swings with uncontrollable laughing or crying

Uncommon

• Changes in the color of the skin, nose, mouth or hair
• Dizziness
• Hair loss
• Decreased reflexes
• Vertigo (spinning sensation)
• Ringing in the ears

Stop taking VOHQ 400 TABLET and contact your doctor immediately if you
experience any of the following side effects:

• Severe allergic reactions (such as skin rash, redness, itching, swallowing or breathing problems, swelling of your lips, face, throat or tongue)
• Blistering of the skin, particularly the mouth, face, nose and genitals, fever and flu-like symptoms such as eosinophilia and systemic symptoms (DRESS), stevens-johnson syndrome
• Lowering of the blood glucose level
• Muscle weakness, muscle spasms or cramps, or changes in sensation of your skin (tingling)
• Eye problems (changes in color of the eye, blurring vision, sensitivity to light)
• Weakening of the heart muscle, chest pain, an irregular or abnormal heartbeat, feeling dizzy or tired, swelling of feet, ankles and legs
• Abnormal bleeding or bruising, tiredness and pale skin
• Recurrent infection such as sore throat, mouth ulcers and fever
• Muscle stiffness, abnormal movements or shivering of body parts
• Altered behavior

How To Manage Side Effects

!### Loss Of Appetite

Eat when you are hungry. Eat smaller meals more often than usual. Snack only
when you're hungry. Eat a nutritious snack that is rich in calories and protein,
such as dried fruit and nuts. Consult your doctor immediately if the symptoms
worsen or persist.

!### Nausea And Vomiting

Stick to simple meals while taking this medicine. Avoid eating oily rich, fried
or spicy foods. Do not lie down or sleep immediately after eating. Consult your
doctor if the symptom does not improve.

!### Skin rash Or Itching

Avoid hot showers because hot water can irritate your skin further. Do not
scratch the affected area. Use protective clothing when going outdoors.
Regularly moisturize your skin. Consult your doctor if the symptom worsens.

!### Stomach Pain

Try to rest and relax. Eat and drink slowly or try to have smaller meals more
frequently. Keep a heat pad on your stomach. If the symptom does not improve,
consult your doctor.

Warning & Precautions

!### Pregnancy

Use with CautionVOHQ 400 TABLET should be used with caution in pregnant women if recommended by
your doctor. Inform your doctor immediately if you become pregnant or think you
may be pregnant while taking VOHQ 400 TABLET.

!### Breastfeeding

Use with CautionVOHQ 400 TABLET should be used with caution in breastfeeding women only if
recommended by your doctor as it can pass through the breast milk. Consult your
doctor before taking VOHQ 400 TABLET.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you experience blurred vision or any eye
problems while taking VOHQ 400 TABLET.

!### Kidney

Use with CautionVOHQ 400 TABLET should be taken with caution in patients with kidneys problems.
Consult your doctor before taking VOHQ 400 TABLET.

!### Liver

Use with CautionVOHQ 400 TABLET should be taken with caution in patients with liver problems.
Consult your doctor for advice before taking VOHQ 400 TABLET.

!### Allergy

ContraindicatedDo not take VOHQ 400 TABLET if you are allergic to Hydroxychloroquine, similar
medicines such as quinolones (Ex. chloroquine) and quinine or any other
ingredients of this medicine.

!### Heart Disease

Use with CautionVOHQ 400 TABLET should be taken with caution in patients with heart disease
(such as cardiomyopathy, abnormal heartbeat, long QT syndrome) or have a history
of heart attack. Consult your doctor before taking VOHQ 400 TABLET.

!### Use In Pediatrics

Use with CautionVOHQ 400 TABLET should be used with caution in children. Your child’s doctor
will decide the dose, duration of management and its frequency depending upon
the child’s age, body weight, severities of disease and other disease
conditions.

!### Use In Geriatrics

Use with CautionVOHQ 400 TABLET should be taken with caution in elderly patients (aged 65 years
and above). Consult your doctor before taking VOHQ 400 TABLET.

Others

VOHQ 400 TABLET is not recommended for use if you:

• Have an eye problem which affects the retina (maculopathy)
• Experience change in eye color or any other problem

Before taking VOHQ 400 TABLET, inform your physician if you:

• Have abnormal blood sugar levels
• Have glucose-6-phosphate dehydrogenase (G6PD) deficiency or porphyria
• Have psoriasis
• Have a blood disorder such as aplastic anemia, agranulocytosis, leukopenia or thrombocytopenia
• Have any problems with nervous system or brain
• Have serious stomach or gut problems
• Have a psychological disorder such as mood swings or suicidal behaviors
• Had a bad reaction to quinine in the past

Interactions

A. Drug-Drug interactions:

Before taking VOHQ 400 TABLET, inform your doctor if you are taking any of the
following medicines:

• Insulin, sulfonylureas such as glimepiride, meglitinide, thiazolidinedione such as pioglitazone, metformin (used to manage diabetes)
• Digoxin, amiodarone (used to manage heart disease)
• Azithromycin, clarithromycin, erythromycin, gentamicin, neomycin, tobramycin and  moxifloxacin (used to manage bacterial infections)
• Cimetidine (used to manage stomach ulcers)
• Neostigmine and pyridostigmine (used to manage myasthenia gravis and muscle weakness)
• Tamoxifen (used to manage eye infections)
• Halofantrine, mefloquine (used to manage malarial infection)
• Amisulpride, quetiapine, risperidone (used to manage psychiatric disorders)
• Rabies vaccine (used to manage rabies)
• Ciclosporin (used to manage organ transplant rejection)
• Praziquantel (used to manage worm infections)
• Agalsidase (used to manage fabry’s disease)
• Carbamazepine, sodium valproate, topiramate (used to manage fits or seizures)

Overdosage:

If you or anyone else accidentally takes more of VOHQ 400 TABLET, consult your
doctor immediately or visit a nearby hospital immediately if the symptoms
worsen. The symptoms may include abnormal or low blood pressure, low potassium
levels in the blood, abnormal heartbeat, depression, seizures, impaired vision,
transient blindness, cardiac arrest, coma or death.

Synopsis

Drug	:	Hydroxychloroquine
Pharmacological Category	:	Antimalarials or Disease Modifying Anti-Rheumatic Drugs
Therapeutic Indication	:	To manage malaria, rheumatoid arthritis, juvenile idiopathic arthritis, discoid and systemic lupus erythematosus, skin problems
Dosage Forms	:	Tablet, Cream

More Information

Storage

• Keep VOHQ 400 TABLET out of reach of children
• Store at room temperature

FAQs About VOHQ 400 TABLET

Q: Can VOHQ 400 TABLET be used during pregnancy?

A: VOHQ 400 TABLET should be used with caution in pregnant women only if advised
by the doctor. Consult your doctor for advice before taking VOHQ 400 TABLET.
Inform your doctor if you are planning or doubt if you are pregnant.

Q: What are the common side effects of VOHQ 400 TABLET?

A: The most common side effects of taking VOHQ 400 TABLET are nausea, vomiting,
loose stools, stomach pain, headache, loss of appetite and skin rashes. Consult
your doctor if any of the side effects worsen.

Q: Is VOHQ 400 TABLET safe for use in patients with diabetes?

A: VOHQ 400 TABLET should be used with caution in patients with diabetes. Inform
your doctor if you have diabetes and taking medicines to manage the condition
such as insulin, sulfonylureas such as glimepiride, meglitinide,
thiazolidinediones such as pioglitazone, metformin, etc. VOHQ 400 TABLET can
lower the blood sugar levels. Consult your doctor if the symptoms worsen or
persist.

Q: Can I stop taking VOHQ 400 TABLET if my symptoms of the disease subside?

A: Though the symptoms of your disease subside, do not stop taking VOHQ 400
TABLET unless recommended by your doctor as the disease and its symptoms may
worsen back again. Consult your doctor for advice.

Q: What happens when you forget to take VOHQ 400 TABLET?

A: If you forget to take a dose of VOHQ 400 TABLET on time, take it as soon as
you remember. However, skip the missing dose if it’s time for the next dose. Do
not take a double dose to make up for a missed dose.

Useful Diagnostic Tests

• Complete blood count
• Liver function test