RITODINE 10mg Injection 1ml

Introduction About RITODINE 10MG INJECTION

RITODINE 10MG INJECTION contains Ritodrine which belongs to a group of medicines
called Tocolytics. It is indicated for the management of uncomplicated Premature
labour.

Premature labour occurs when regular contractions result in the opening of the
cervix after 20th week and before 37th week of pregnancy. It can result in
premature birth. The earlier premature birth happens, the greater the health
risks for the baby.

RITODINE 10MG INJECTION is not recommended for use in patients with known
hypersensitivity reactions, cardiac disease like myocardial ischaemia,
antepartum haemorrhage, intra-uterine infection, intra-uterine fetal death,
placenta praevia, abru
eclampsia or severe pre-eclampsia.

Before receiving this medicine inform your doctor if you have cardiac diseases,
hypertension, hyperthyroidism, hypokalaemia, diabetes mellitus, mild to moderate
pre-eclampsia, blood pressure and pulse rate and avoid over-hydration while
receiving this medicine.

There are no adequate and well controlled studies of effects in pregnant women
before 20 weeks gestation. It should not be used before the 20th week of
pregnancy. Studies in pregnant women from the 20th week of gestation onwards
have not shown increased risk of fetal abnormalities. Therefore, it should be
used only when clearly indicated by the physician.

The most common side effects of receiving are nausea, vomiting, flushing,
sweating, tremor, hypokalaemia, tachycardia, palpitations, hypotension (left
lateral position throughout infusion to minimize risk), uterine bleeding and
pulmonary oedema. Consult your doctor if any of the above side effects worsen or
persist for a long duration.

Uses Of RITODINE 10MG INJECTION

• Used to manage uncomplicated premature labour

How RITODINE 10MG INJECTION Works

RITODINE 10MG INJECTION belongs to β2–adrenergic agonist which relaxes the
uterus by stimulating the β2–adrenergic receptors of the uterine muscle, which
causes a decrease in the intensity and frequency of uterine contractions. It
eases the contraction of the uterus and helps relaxing it, thereby managing
premature delivery.

How to use RITODINE 10MG INJECTION

RITODINE 10MG INJECTION will be administered intravenously or intramuscularly by
your doctor or nurse. Your doctor will decide the right dose depends on your
age, body weight and health condition.

Side Effects Of RITODINE 10MG INJECTION

Common

• nausea, vomiting
• flushing
• sweating
• tremors
• hypokalaemia
• tachycardia, palpitations
• hypotension (left lateral position throughout infusion to minimize risk)
• uterine bleeding
• pulmonary oedema
• chest pain or tightness
• arrhythmias
• salivary gland enlargement
• leucopenia, agranulocytosis
• liver function abnormalities including increased transaminases and hepatitis
• headache
• nervousness
• anxiety

Rare

Stop receiving and contact your doctor immediately, if you experience the
following:

• lung swelling
• severe allergic reactions

How To Manage Side Effects

Headache

Rest and relax. Drink plenty of fluids such as water and apply a pain-relieving
balm on the head if necessary. Do not consume alcohol. Contact your doctor if
headache worsens.

!### Nausea And Vomiting

Try to take this medicine with or just after a meal or a snack. Stick to simple
meals. Avoid eating rich or spicy food.

Warning & Precautions

!### Pregnancy

Consult your doctorThere are no adequate and well controlled studies of effects in pregnant women
before 20 weeks gestation. It should not be used before the 20th week of
pregnancy. Therefore, it will be administered only when clearly indicated by the
physician. Consult your doctor for advice.

!### Breastfeeding

Use with CautionRITODINE 10MG INJECTION should be used with caution in breastfeeding women.
Consult your doctor before taking this medicine.

!### Allergy

ContraindicatedDo not receive if you are allergic to Ritodrine or any other ingredients of this
medicine.

!### Lungs

Use with CautionRITODINE 10MG INJECTION should be used with caution in patients suffering from
lung disease such as bronchial asthma. Consult your doctor for advice before
receiving.

!### Heart Disease

Consult your doctorRITODINE 10MG INJECTION is not recommended in patients with heart diseases such
as myocardial ischaemia. It should be used with caution in patients suffering
from myocardial insufficiency, arrhythmias. Before receiving, discuss the risks
and benefits with your doctor.

Others

Do not receive RITODINE 10MG INJECTION, if you have:

• antepartum haemorrhage
• intra-uterine infection
• intra-uterine fetal death
• placenta praevia
• abru
• threatened miscarriage
• cord compression
• eclampsia or severe preeclampsia

Before receiving RITODINE 10MG INJECTION, inform your doctor if you have:

• hypertension
• hyperthyroidism
• hypokalaemia
• diabetes mellitus
• mild to moderate preeclampsia
• pulmonary oedema

Interactions

A. Drug-Drug interactions:

Before receiving RITODINE 10MG INJECTION inform your doctor if you are taking
the following medicines:

• corticosteroids
• diuretics (acetazolamide, loop diuretics and thiazides)
• theophylline (used for breathing problems)
• sympathomimetic medicines
• β–adrenergic blocking medicines
• anesthetics (used for surgery)
• neuromuscular blockers such as pancuronium, vecuronium
• potassium-depleting medicines

Overdosage:

Your doctor or nurse will administer the RITODINE 10MG INJECTION, so it is
unlikely to cause overdosage. If you experience any unusual side effects after
receiving RITODINE 10MG INJECTION, consult your doctor immediately. Symptoms of
overdose includes tachycardia (maternal and fetal), palpitation, cardiac
arrhythmia, hypotension, nervousness, tremor, nausea, and vomiting.

Synopsis

Drug	:	Ritodrine
Pharmacological Category	:	Tocolytics
Therapeutic Indication	:	Uncomplicated premature labour
Dosage Forms	:	Tablet, Injection

More Information

• Keep out of reach of children
• Store at room temperature

FAQs About RITODINE 10MG INJECTION

Q: How RITODINE 10MG INJECTION will be administered?

A: RITODINE 10MG INJECTION will be administered intravenously or intramuscularly
by your doctor or nurse. Your doctor will decide the right dose depends on your
age, body weight and health condition.

Q: Does RITODINE 10MG INJECTION causeheadache?

A: Yes, this medicine may cause headache in some individuals. Rest and relax.
Drink plenty of fluids such as water and apply a pain-relieving balm on the head
if necessary. Do not consume alcohol. Contact your doctor if headache worsens.

Q: Is this medicine safe in diabetic patients?

A: This medicine may increase blood glucose levels. So, it should be used with
caution in pregnant women with diabetes mellitus. In addition, this medicine is
not recommended to use in pregnant women with uncontrolled diabetes.

Q: Does RITODINE 10MG INJECTION manage high blood pressure during pregnancy?

A: No, it doesn’t manage high blood pressure during pregnancy. Consult your
doctor for advice before taking this medicine.

Q: Is RITODINE 10MG INJECTION safe?

A: Yes, it is safe if used in the dose and duration advised by your doctor.
Consult your doctor for advice before taking this medicine.