Pomalong 4mg Capsule 21'S

Introduction About POMALONG 4MG CAPSULE

POMALONG 4MG CAPSULE contains Pomalidomide which belongs to the group of
medicines called Immunomodulating agents. It is used in adults to manage
multiple myeloma (cancer of plasma cells). It is generally used in combination
with other anti-cancer agents (such as dexamethasone and/or bortezomib) to
achieve better results.

Before taking POMALONG 4MG CAPSULE inform your doctor if you have any liver,
kidney or heart problems. You must also inform your doctor if you have high
blood pressure, high blood cholesterol levels, blood clots or hepatitis B
infection or have a habit of smoking as a precaution.

POMALONG 4MG CAPSULE is not recommended for use in women who are pregnant, think
that they might be pregnant or planning to become pregnant. It should be used in
breastfeeding women only if considered necessary by the physician.

Both men and women undergoing therapy with POMALONG 4MG CAPSULE must use a
suitable contrace
weeks after stopping the therapy. Patients taking POMALONG 4MG CAPSULE must not
donate their blood during management and for 7 days after the end of management

The most common side effects of taking POMALONG 4MG CAPSULE are increased
infections, low RBC and platelet count, nausea, vomiting, swelling of body
parts, numbness or tingling of body parts, skin rashes, oral sores, taste
changes and weight loss. Consult your doctor if any of these side effect
troubles you.

Uses Of POMALONG 4MG CAPSULE

• Manage multiple myeloma (cancer of plasma cells) in adults

How POMALONG 4MG CAPSULE Works

POMALONG 4MG CAPSULE stimulates the immune system to stop the growth of abnormal
plasma cells (a type of white blood cells) in the blood. This helps in
destroying the cancer cells in the blood and manages it from developing further.
It also reduces blood supply to the cancer cells, which helps in managing
further spread of cancer cells in the body.

How to use POMALONG 4MG CAPSULE

Take POMALONG 4MG CAPSULE as advised by your doctor. Swallow the medicines with
a glass of water. Do not crush or chew the medicine. It can be taken with or
without food.

Your doctor will decide the correct dose and duration of therapy for you
depending upon your age, body weight and health condition. Do not stop taking
POMALONG 4MG CAPSULE unless your doctor tells you to stop.

Side Effects Of POMALONG 4MG CAPSULE

Common

• shortness of breath
• infections of lung or respiratory tract (bronchitis, sinusitis, pneumonia)
• anaemia (low RBC in blood causing tiredness and weakness)
• low blood sodium, potassium, magnesium and phosphate levels
• high blood calcium levels
• elevated blood sugar levels
• nausea, vomiting, constipation, diarrhoea, loss of appetite, stomach pain
• lack of energy, muscle weakness
• difficulty in sleeping
• dizziness, tremor, spinning sensation
• numbness, tingling or burning sensation on the body
• swelling of the arms and leg or body
• skin rash, itching, shingles
• high blood pressure
• high uric acid levels in blood
• changes in taste, mouth ulcers, dry mouth
• feeling confused, depression
• urinary tract infections
• weight loss

Uncommon

• tumour lysis syndrome (toxin accumulation in blood due to breakdown of cancer cells)
• decreased thyroid functions

Rare

Stop taking POMALONG 4MG CAPSULE and contact your physician immediately if you
experience any of the following side effects:

• signs of infections (such as fever, chills, sore throat, cough, mouth ulcers or any other signs of infection)
• increased bleeding or bruising, nasal bleeds, bleeding in the gut
• signs of sepsis (such as fever, chills, low urine output, nausea and vomiting, confusion, rapid breathing)
• severe persistent bloody diarrhea
• signs of blood clot (such as chest pain, shortness of breath, leg pain and swelling, heart failure)
• signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth, or throat which can lead to difficulty in breathing or swallowing)
• skin cancer, changes in skin colour
• signs of liver damage (such as yellowish discolouration of the skin and eyes, dark, brown-coloured urine, right-sided abdominal pain, fever, nausea and vomiting)
• signs of severe allergic skin reactions (such as skin rash on the face or whole body, redness, high fever, flu-like symptoms with enlarged lymph nodes)
• signs of posterior leukoencephalopathy syndrome (a nerve disorder causing bnormal vision from blurriness to vision loss, problems in walking and speaking, loss of balance, weak arms or legs, memory loss, confusion, fits, headache, numbness of body parts)

How To Manage Side Effects

Skin rash:

Avoid hot showers because hot water can irritate your skin further. Do not
scratch the affected area. Use protective clothing when going outdoors.
Regularly moisturize your skin. Consult your doctor if your skin rash worsens.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or
machines completely while you are feeling dizzy. Consult your doctor if your
dizziness worsens.

Nausea and Vomiting:

Stick to simple meals. Avoid eating oil rich or spicy foods. If your nausea
worsens, consult your doctor for advice.

Mouth ulcers:

Avoid eating spicy foods. Drink plenty of water. Apply a pain-relieving gel on
the affected areas of the mouth if required. Consult your doctor if the symptom
did not improve.

Warning & Precautions

!### Pregnancy

POMALONG 4MG CAPSULE may harm the unborn baby. Therefore, it should not be used
in pregnant women and in women who are planning to become pregnant or think that
they might be pregnant. Women of childbearing potential must use a suitable
contrace
and until 4 weeks after stopping therapy with POMALONG 4MG CAPSULE. If you
accidentally became pregnant while undergoing therapy with POMALONG 4MG CAPSULE,
stop taking this medicine and inform your doctor immediately.

!### Breastfeeding

It is not known whether POMALONG 4MG CAPSULE passes through breast milk or not.
Therefore, it should be used in breastfeeding women only if considered necessary
by the physician.

!### Driving and Using Machines

Do not drive or operate any machines if you feel dizzy, tired or faint after
taking POMALONG 4MG CAPSULE.

!### Kidney

POMALONG 4MG CAPSULE should be used with caution in patients with kidney
problems. Therefore, consult your doctor before taking it

!### Liver

POMALONG 4MG CAPSULE should be used with caution in patients with liver
problems. Therefore, consult your doctor before taking it.

!### Allergy

Do not take POMALONG 4MG CAPSULE if you are allergic to pomalidomide,
lenalidomide or thalidomide.

!### Heart Disease

POMALONG 4MG CAPSULE should be used with caution in patients with heart failure
or a recent heart attack. Therefore, consult your doctor before taking it.

Others

Before taking POMALONG 4MG CAPSULE, inform your doctor if you:

• have ever had blood clots in the past
• have a habit of smoking
• have high blood cholesterol levels
• have high blood pressure
• have breathing difficulties
• have excessive tumours in your body (including tumours of bone marrow)
• have or ever had nerve damage or nerve pain
• have or ever had hepatitis B infection

Use in paediatrics:

POMALONG 4MG CAPSULE is not suitable for use in children and adolescents (aged
below 18 years). Therefore, consult your doctor before taking it.

Use in geriatrics:

POMALONG 4MG CAPSULE should be used with caution in elderly patients (aged 65
years or above). Therefore, consult your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking POMALONG 4MG CAPSULE, inform your doctor if you are taking any of
the following medicines such as:

• ketoconazole (used to manage fungal infections)
• ciprofloxacin, enoxacin (medicines used for bacterial infections)
• fluvoxamine (used to manage depression)

Overdosage:

If you or anyone else accidentally took more POMALONG 4MG CAPSULE, consult your
doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Pomalidomide
Pharmacological Category	:	Immunomodulating agents
Therapeutic Indication	:	Multiple myeloma
Dosage Forms	:	Capsule

More Information

• Keep POMALONG 4MG CAPSULE out of the sight and reach of children
• Store POMALONG 4MG CAPSULE at room temperature

FAQs About POMALONG 4MG CAPSULE

What POMALONG 4MG CAPSULE is used for?

POMALONG 4MG CAPSULE is used in adults to manage multiple myeloma (cancer of
plasma cells). It is generally used in combination with other anti-cancer agents
(such as dexamethasone and/or bortezomib) to achieve better results.

How POMALONG 4MG CAPSULE works on my body?

POMALONG 4MG CAPSULE stimulates the immune system to stop the growth of abnormal
plasma cells (a type of white blood cells) in the blood. This helps in
destroying the cancer cells in the blood and manages it from developing further.
It also reduces blood supply to the cancer cells, which helps in managing
further spread of cancer cells in the body.

Can POMALONG 4MG CAPSULE manage cancer?

Multiple myeloma generally cannot be managed. However, management with POMALONG
4MG CAPSULE can reduce the signs and symptoms of the disease or make them
disappear for a short period. For more information, consult your doctor for
advice.

Can the use of POMALONG 4MG CAPSULE cause weight loss?

Weight loss is one of the common side effects of taking POMALONG 4MG CAPSULE. If
it bothers you, consult your doctor for advice.

Can the use of POMALONG 4MG CAPSULE cause mouth ulcers?

Mouth ulcers are one of the common side effects of taking POMALONG 4MG CAPSULE.
Avoid eating spicy foods. Drink plenty of water. Apply a pain-relieving gel on
the affected areas of the mouth if required. Consult your doctor if the symptom
did not improve

Can POMALONG 4MG CAPSULE be used in children?

POMALONG 4MG CAPSULE should not be used in children aged below 18 years.
Therefore, consult your doctor before taking it.

Is POMALONG 4MG CAPSULE a chemo drug?

Yes. POMALONG 4MG CAPSULE contains a medicine called pomalidomide which is an
immunomodulating agent with anti-cancer properties. It stimulates the immune
system to stop the growth of abnormal plasma cells (a type of white blood cells)
in the blood.

What precautions must be followed while taking POMALONG 4MG CAPSULE?

Before taking POMALONG 4MG CAPSULE inform your doctor if you have any liver,
kidney or heart problems. Inform your doctor before taking POMALONG 4MG CAPSULE
if you are a pregnant or a breastfeeding woman. Men and women taking POMALONG
4MG CAPSULE must use a suitable contrace
undergoing therapy with POMALONG 4MG CAPSULE.

What happens if I stop taking POMALONG 4MG CAPSULE?

No. Do not stop taking POMALONG 4MG CAPSULE without consulting your doctor as it
may make your symptoms reappear. Therefore, take POMALONG 4MG CAPSULE as advised
by your doctor for the stipulated duration.

Can POMALONG 4MG CAPSULE be used during pregnancy?

POMALONG 4MG CAPSULE is generally not recommended for use in pregnant women. If
you accidentally became pregnant while taking POMALONG 4MG CAPSULE, inform your
doctor immediately.

Can the use of POMALONG 4MG CAPSULE make me feel tired?

Yes. POMALONG 4MG CAPSULE may make you feel tired easily. This is because, it
reduces the levels of red blood cells in your blood and may make you anaemic.
Consult your doctor if you experience tiredness after taking POMALONG 4MG
CAPSULE. Tiredness can also occur if you have any pre-existing disease
conditions such as liver or kidney impairment while taking this medicine.

Can I drive a car after takingPOMALONG 4MG CAPSULE?

POMALONG 4MG CAPSULE may make you feel tired or dizzy. Therefore, do not drive
or operate any heavy tools or machines if your ability is affected by POMALONG
4MG CAPSULE.

How to take POMALONG 4MG CAPSULE?

Take POMALONG 4MG CAPSULE as advised by your doctor. Swallow the medicines with
a glass of water. Do not crush or chew the medicine. It can be taken with or
without food.

How to control nausea caused due to POMALONG 4MG CAPSULE?

Generally, anticancer medicines are associated with uncontrollable nausea and
vomiting. To avoid this, your doctor would prescribe a suitable medicine to
control them along with POMALONG 4MG CAPSULE. If not, consult your doctor for a
suitable anti-emetic medicine. Do not self-manage nausea.

What are the side effects of taking POMALONG 4MG CAPSULE?

The most common side effects of taking POMALONG 4MG CAPSULE are increased
infections, low RBC and platelet count, nausea, vomiting, swelling of body
parts, numbness or tingling of body parts, skin rashes, oral sores, taste
changes and weight loss. Consult your doctor if any of these side effect
troubles you.

Who should avoid taking POMALONG 4MG CAPSULE?

POMALONG 4MG CAPSULE is not recommended for use if you are allergic to
pomalidomide. It is also not recommended for use in pregnant or breastfeeding
women and in children (aged below 18 years).

IsPOMALONG 4MG CAPSULE safe to use in kidney disease?

POMALONG 4MG CAPSULE should be used with caution in patients with kidney
problems. Your doctor will access your health condition and suggest a suitable
dose for you.

Can the use of POMALONG 4MG CAPSULE affect the liver?

Yes. POMALONG 4MG CAPSULE may affect the way your liver work. It can elevate the
levels of certain liver enzymes in your body. Therefore, it should be used with
caution in patients with liver problems. Consult your doctor before taking it.

Useful Diagnostic Tests

• Albumin/Globulin Ratio, Serum
• Calcium
• Complete Blood Count
• Kidney Function Test