IWATA 500mg Tablet 10's

Introduction About IWATA 500MG TABLET

IWATA 500MG TABLET contains Sulfasalazine which belongs to the group of
medicines called Aminosalicylates. It is used to manage inflammatory bowel
disease such as Ulcerative Colitis, Crohn’s disease and rheumatoid arthritis.

Ulcerative Colitis is an inflammatory disease which affects only the large bowel
(colon and back passage), the lining of the bowel becomes inflamed (red and
swollen) and symptoms include abdominal pain and diarrhea (may have blood and
mucus).

Crohn’s disease is an inflammatory disease which affect any part of the
digestive system from the mouth to the anus, most commonly affects the last part
of the small bowel and the first part of the large bowel, symptoms include
abdominal pain and diarrhea (may be bloody). It can also be used to manage
rheumatoid arthritis (swelling, pain, stiffness of joints)

Your doctor might want you to take certain blood, kidney and liver function
tests during the management. Drink enough fluids during this management to avoid
problems with kidney.

Before taking IWATA 500MG TABLET inform your doctor if you have porphyria (a
rare blood pigment disorder), jaundice, kidney, liver, blood problems,
glucose-6-phosphate dehydrogenase deficiency, history of recurring chronic
infection, asthma, arthritis.

Inform your doctor if you are pregnant or breastfeeding. IWATA 500MG TABLET is
not recommended for use in children below 2 years of age.

The most common side effects of taking IWATA 500MG TABLET are indigestion,
heartburn, nausea, dizziness and headache. Consult your doctor if side effects
gets worse.

Uses Of IWATA 500MG TABLET

It is used to manage:

• ulcerative colitis
• crohn’s disease
• rheumatoid arthritis

How IWATA 500MG TABLET Works

IWATA 500MG TABLET works by suppressing the overactivity of the immune system in
autoimmune diseases and blocks the chemical messengers that cause inflammation
(swelling).

How to use IWATA 500MG TABLET

Take IWATA 500MG TABLET as advised by your physician. Swallow the medicine with
water. Do not crush or chew the medicine. Your doctor will decide the right dose
and duration depending upon your age, body weight and disease condition.

Side Effects Of IWATA 500MG TABLET

Common

• indigestion
• heartburn
• nausea
• dizziness
• headache
• changes in taste
• ringing in the ears
• cough
• itching of the skin
• purple discolorations on the skin
• joint pain
• protein in urine
• fever

Uncommon

• depression
• shortness of breath
• abdominal pain
• diarrhea
• vomiting
• hair loss
• hives
• puffiness around the eyes and face

Rare

Stop taking IWATA 500MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• allergic reaction such as sudden wheeziness, difficulty in breathing, swelling of eyelids, face or lips, rash or itching (affecting the whole body)
• jaundice
• severe skin rash that causes blistering (affects the mouth and tongue), life-threatening skin rashes (exfoliate dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis)
• fever, pains in your joints, hives, swollen glands, rash and itching (signs of serum sickness)
• any unexplained bleeding
• bruising, fever, rash, pallor (paleness), severe sore throat or tiredness (signs of abnormality in blood)
• rash or fever or swollen gland may be a sign of DRESS (drug rash with eosinophilia and systemic symptoms)

How To Manage Side Effects

Nausea:

Stick to simple meals. Avoid eating oily or spicy food. Inform your doctor if
symptoms do not reduce.

Headache:

Avoid bright lights, drink lots of water and take rest. Inform your doctor if
symptoms do not reduce.

Cough:

Drink more of warm water, take honey, ginger for relief. Taking steam also
helps. Inform your doctor if symptoms do not reduce.

Indigestion:

Eat smaller meals, chew the food thoroughly. drink lemon or ginger tea. Inform
your doctor if symptoms do not reduce.

Warning & Precautions

!### Pregnancy

Inform your doctor if you are pregnant or planning to have a baby before taking
IWATA 500MG TABLET. Your doctor will decide whether to take it or not.

!### Breastfeeding

Avoid breastfeeding while taking IWATA 500MG TABLET as there have been reports
of diarrhea or blood in the stools of babies. Consult your doctor before taking
it.

!### Driving and Using Machines

IWATA 500MG TABLET is unlikely to affect your ability to drive or use machines.

!### Kidney

IWATA 500MG TABLET should be used with caution in patients with kidney disease.
Consult your doctor before taking.

!### Liver

IWATA 500MG TABLET should be used with caution in patients with liver disease.
Consult your doctor before taking.

!### Allergy

Do not take IWATA 500MG TABLET if you are allergic to Sulfasalazine, salicylates
(Ex. aspirin) or sulfonamides (type of antibiotic) or any other ingredients of
this medicine.

!### Lungs

IWATA 500MG TABLET should be used with caution in patients with asthma. Consult
your doctor before taking.

Others

IWATA 500MG TABLET is not recommended for use if you:

• have porphyria (a rare blood pigment disorder)
• have jaundice

Before taking IWATA 500MG TABLET, inform your doctor if you:

• have blood disorders
• have glucose-6-phosphate dehydrogenase deficiency (an inherited condition)
• have a history of recurring chronic infections
• your child has arthritis

Use in pediatrics:

IWATA 500MG TABLET is not recommended for use in children below 2 years of age.
Consult your doctor before taking.

Use in geriatrics:

IWATA 500MG TABLET should be used with caution in elderly patients. Consult your
doctor before taking.

Interactions

A. Drug-Drug interactions:

Before taking IWATA 500MG TABLET, inform your doctor if you are taking any of
the following medicine:

• medicine for high blood sugar (Ex. metformin, glipizide)
• digoxin (to manage heart failure)
• folic acid or folate (Ex. Spina Bifida) to reduce risk of neural tube defect
• azathioprine and mercaptopurine (help to suppress your body’s immune response in organ transplantation and certain chronic inflammations (Ex. rheumatoid arthritis))
• methotrexate (used to manage rheumatoid arthritis)
• methenamine (for managing urinary tract infections)

Overdosage:

If you or anyone else accidentally takes too much of IWATA 500MG TABLET, consult
your doctor immediately or visit the nearby hospital. Symptoms of overdose are
nausea and vomiting.

Synopsis

Drug	:	Sulfasalazine
Pharmacological Category	:	Anti-inflammatory
Therapeutic Indication	:	Ulcerative colitis, Crohn’s disease, Rheumatoid arthritis
Dosage Forms	:	Tablet

More Information

• Keep IWATA 500MG TABLET out of reach of children
• Store below 25°C

FAQs About IWATA 500MG TABLET

What is IWATA 500MG TABLET used for?

IWATA 500MG TABLET is used to manage inflammation caused by rheumatoid arthritis
or inflammatory bowel disease (ulcerative colitis, Crohn’s disease). You must
talk to a doctor if you do not feel better or if you feel worse.

Can IWATA 500MG TABLET be used in children?

IWATA 500MG TABLET is not recommended for use in children below 2 years of age.
It is not recommended if you have systemic-onset juvenile rheumatoid arthritis
(Stills disease). Consult your doctor before taking.

What if I take more of IWATA 500MG TABLET accidentally?

If you or anyone else accidentally take too much of IWATA 500MG TABLET, consult
your doctor immediately or visit the nearby hospital. Symptoms of overdose are
nausea and vomiting.

How does IWATA 500MG TABLET work?

IWATA 500MG TABLET works by suppressing the overactivity of the immune system in
autoimmune diseases and blocks the chemical messengers that cause inflammation
(swelling).

Any tests to be taken while on management with IWATA 500MG TABLET?

Your doctor will take blood tests to check your blood, urine (for protein),
kidneys before you start management with IWATA 500MG TABLET and regularly during
management.

Useful Diagnostic Tests

• Blood and urine test
• Kidney function test
• Liver test