Trisulfose DS Tablet 10'S

Introduction About TRISULFOSE DS TABLET

TRISULFOSE DS TABLET is a combination of Sulphamethoxazole and Trimethoprim
which belongs to the group of medicines called Antibiotics. It is used to manage
lung infections (pneumonia or Pneumocystis jiroveci pneumonia) caused by a
bacteria called Pneumocystis jirovecii and toxoplasmosis (infection with the
Toxoplasma gondii parasite).

It can also be used to manage urinary tract infections, respiratory tract
infections (such as bronchitis), ear infections (such as otitis media) and an
infection called nocardiosis which can affect the lungs, skin and brain.
TRISULFOSE DS TABLET is suitable for use both in adults and in adolescents (aged
12 years or above).

Take TRISULFOSE DS TABLET for the stipulated duration as instructed by your
doctor even if you feel better during the midway of the therapy to achieve
better results. Failing to complete the full course of the therapy or skipping
doses in between the therapy may not result in adequate infection control.

Before taking TRISULFOSE DS TABLET inform your doctor if you have any liver or
kidney problems. You must also inform your doctor if you have asthma, any
allergic conditions, genetic disorders, blood-related disorders, folic acid
deficiency, high blood potassium levels or if you are malnourished as a
precaution.

Consult your doctor before taking this medicine if you are pregnant or
breastfeeding. The most common side effects of taking TRISULFOSE DS TABLET are
headache, nausea, diarrhea, high blood potassium levels, fungal infections of
the mouth or vagina and skin rashes. Consult your doctor if any of these side
effects troubles you.

Uses Of TRISULFOSE DS TABLET

It is used in adults and in adolescents (aged 12 years or above) to manage the
following bacterial infections:

• Lung infections (Ex. Pneumonia or Pneumocystis jiroveci pneumonia) caused by a bacteria called Pneumocystis jirovecii
• Toxoplasmosis (an infection with the Toxoplasma gondii parasite)
• Urinary tract infections
• Respiratory tract infections (Ex. bronchitis)
• Ear infections (Ex. otitis media)
• Nocardiosis (a bacterial infection that affects the lungs, skin and brain)

How TRISULFOSE DS TABLET Works

TRISULFOSE DS TABLET is a powerful antibiotic. It kills the susce
by blocking the production of certain essential vitamins (folate) that are
necessary for the bacteria to grow, multiply and survive. Therefore, it destroys
the susce
within the body which helps in reducing the severity of the infection.

How to use TRISULFOSE DS TABLET

Take TRISULFOSE DS TABLET as advised by your physician. Swallow TRISULFOSE DS
TABLET with a glass of water. Do not crush or chew the medicine. TRISULFOSE DS
TABLET can be taken with or without food.

Your doctor will decide the correct dose and duration of therapy for you
depending on your age, body weight and severity of the infection.

Do not stop taking TRISULFOSE DS TABLET once your symptom subsides. It is
important to take TRISULFOSE DS TABLET for the stipulated duration as
recommended by your doctor to achieve better results.

Side Effects Of TRISULFOSE DS TABLET

Common

• high potassium levels in blood causing abnormal heartbeats
• fungal infection (thrush or candidiasis) of mouth or vagina
• headache, nausea, diarrhoea
• skin rashes

Uncommon

• vomiting

Rare

Stop taking TRISULFOSE DS TABLET and contact your doctor immediately if you
experience any of the following side effects:

• severe allergic reactions (such as skin rashes, itching, swelling of the face, lips, tongue or throat causing difficulty in breathing or swallowing, chest pain and fainting)
• severe skin reactions (such as generalised skin redness with pustules accomp
• signs of abnormal WBC count (such as fever, swollen glands, weakness, light-headedness, shortness of breath, bruising with or without skin rash)
• unexpected worsening of cough and shortness of breath

How To Manage Side Effects

!### Diarrhea

Drink plenty of fluids, such as water or fruit juice to keep yourself hydrated.
Consuming ORS can also be beneficial. Do not consume any medicine on your own
without consulting your doctor. If your diarrhea worsens, contact your doctor
immediately.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate your
headache. Consult your doctor if your headache worsens.

!### Nausea And Vomiting

Take TRISULFOSE DS TABLET with, or just after meals. Stick to simple meals.
Avoid eating oil-rich or spicy foods. Please consult your doctor immediately if
you experience severe nausea and vomiting.

Warning & Precautions

!### Pregnancy

Use with CautionTRISULFOSE DS TABLET should be used with caution in pregnant women. Therefore,
consult your doctor for advice before taking it.

!### Breastfeeding

Use with CautionTRISULFOSE DS TABLET should be used with caution in breastfeeding women.
Therefore, consult your doctor for advice before taking it.

!### Driving and Using Machines

Use with CautionDo not drive or operate any heavy tools or machines if your ability is affected
by TRISULFOSE DS TABLET.

!### Alcohol

Consult your doctorAvoid consum

!### Kidney

Consult your doctorTRISULFOSE DS TABLET is not recommended for use in patients with severe kidney
problems. It should be used with caution in patients with other kidney problems.
Therefore, consult your doctor before taking it.

!### Liver

ContraindicatedTRISULFOSE DS TABLET is not recommended for use in patients with severe liver
problems. Therefore, consult your doctor before taking it.

!### Allergy

ContraindicatedDo not take TRISULFOSE DS TABLET if you are allergic to Sulphamethoxazole,
trimethoprim, sulphonamide medicines (such as gliclazide, glibenclamide) or to
thiazide diuretics (such as Bendroflumethiazide).

!### Lungs

Use with CautionTRISULFOSE DS TABLET should be used with caution in patients with asthma.
Therefore, consult your doctor before taking it.

!### Use In Pediatrics

ContraindicatedTRISULFOSE DS TABLET is not recommended for use in children and adolescents
(aged below 12 years). However, consult your doctor for advice before taking it.

!### Use In Geriatrics

Use with CautionTRISULFOSE DS TABLET should be used with caution in elderly patients. Therefore,
consult your doctor for advice before taking it.

Others

TRISULFOSE DS TABLET is not recommended for use if you:

• ever had bleeding problems (such as thrombocytopenia)
• have porphyria (a rare blood disorder)

Before taking TRISULFOSE DS TABLET, consult your doctor if you:

• have any allergic conditions (such as watery eyes, itchy nose, repeated sneezing)
• have anemia or vitamin B9 (folic acid) deficiency
• have G6PD deficiency (a genetic disorder that affect metabolism)
• have phenylketonuria (build-up of an amino acid called phenylal
• are underweight or malnourished
• have high blood potassium levels
• have very low RBC, WBC and platelet counts in blood

Interactions

A. Drug-Drug Interactions:

Before taking TRISULFOSE DS TABLET, inform your doctor if you are taking any of
the following medicines such as:

• diuretics (medicines used to remove excess water from the body) such as furosemide, hydrochlorothiazide
• pyrimethamine (a medicine used to manage malaria)
• medicines used for blood thinning (such as warfarin)
• phenytoin (a medicine used to manage epilepsy)
• medicines used to manage diabetes (such as glibenclamide, glipizide, tolbutamide or repaglinide)
• rifampicin (an antibiotic used to manage tuberculosis)
• medicines used to manage heart problems (such as digoxin or procainamide)
• amantadine (a medicine used to manage Parkinson’s disease)
• medicines used to manage HIV infections (such as zidovudine or lamivudine)
• medicines that can increase the amount of potassium in blood, such as potassium-sparging diuretics (Ex. spironolactone, acetazolamide), certain steroids (like prednisolone) or ACE inhibitors (Ex. captopril, enalapril, lisinopril)
• medicines used to suppress immune function and to manage graft rejection (such as ciclosporin, azathioprine)
• methotrexate (a medicine used to manage certain cancers or joint pain)
• folinic acid (a type of vitamin B9 supplement)
• contrace

B. Drug-Food Interaction:

TRISULFOSE DS TABLET is preferably taken with meals to avoid unwanted stomach
problems. However, it can also be taken on an empty stomach. Avoid consuming
foods rich in potassium while taking this medicine.

Overdosage:

If you or anyone else accidentally took more TRISULFOSE DS TABLET, consult your
doctor immediately or visit the nearby hospital. Symptoms of overdosage might
include nausea, vomiting, dizziness and confusion.

Synopsis

Drug	:	Sulphamethoxazole, Trimethoprim
Pharmacological Category	:	Sulphonamides, Diaminopyrimidine
Therapeutic Indication	:	Bacterial Infections
Dosage Forms	:	Tablet, Syrup, Suspension, Injection, Infusion, Eye drops

More Information

• Keep TRISULFOSE DS TABLET out of reach of children
• Store TRISULFOSE DS TABLET at room temperature

FAQs About TRISULFOSE DS TABLET

Q: What is the use of TRISULFOSE DS TABLET?

A: TRISULFOSE DS TABLET is used to manage severe bacterial infections including
lung infections, toxoplasmosis (infection with the Toxoplasma gondii parasite),
urinary tract infections, respiratory tract infections (such as bronchitis), ear
infections (such as otitis media) and an infection called nocardiosis which can
affect the lungs, skin and brain.

Q: How TRISULFOSE DS TABLET works in my body?

A: TRISULFOSE DS TABLET is a powerful antibiotic. It kills the susce
bacteria by blocking the production of certain essential vitamins (folate) that
is necessary for the bacteria to grow, multiply and survive. Therefore, it
destroys the susce
multiplication within the body which helps in reducing the severity of the
infection.

Q: How should I take TRISULFOSE DS TABLET?

A: Take TRISULFOSE DS TABLET as advised by your physician. It can be taken with
or without food. Swallow the medicine with a glass of water. Do not crush or
chew the medicine.

Q: For how long should I take TRISULFOSE DS TABLET?

A: TakeTRISULFOSE DS TABLET for the stipulated duration as prescribed by your
doctor. Do not skip the medicine or stop taking it on your own as it can cause
the infection to reappear.

Q: Can TRISULFOSE DS TABLET be given to pregnant women?

A: TRISULFOSE DS TABLET should be used with caution in pregnant women.
Therefore, consult your doctor for advice before taking it.

Q: What precautions should I follow while taking TRISULFOSE DS TABLET?

A: Before taking TRISULFOSE DS TABLET inform your doctor if you have any liver
or kidney problems. You must also inform your doctor if you have asthma, any
allergic conditions, genetic disorders, blood-related disorders or if you are
malnourished as a precaution. Consult your doctor before taking this medicine if
you are pregnant or breastfeeding. Regularly visit your doctor for check-up and
perform all medical tests recommended by your doctor without fail. Take
TRISULFOSE DS TABLET for the stipulated duration recommended by your doctor to
achieve better results. Failing to do so may cause the symptom to re-occur.

Q: What are the common side effects of taking TRISULFOSE DS TABLET?

A: The most common side effects of taking TRISULFOSE DS TABLET are headache,
nausea, diarrhea, high blood potassium levels, fungal infections of mouth or
vagina and skin rashes. Consult your doctor if any of these side effects
troubles you.

Q: Can I stop taking TRISULFOSE DS TABLET once my symptoms subside?

A: Do not stop taking this medicine once your symptom subsides. It is important
to take the full course of TRISULFOSE DS TABLET to achieve better results.
Failing to complete the full course of the therapy or skipping doses in between
the therapy may not result in adequate infection control. It may also cause your
symptoms to reappear.

Q: Can the use of TRISULFOSE DS TABLET cause diarrhea?

A: TRISULFOSE DS TABLET may cause diarrhea in some individuals. If you
experience diarrhea, drink plenty of fluids, such as water or fruit juice to
keep yourself hydrated. Consuming ORS can also be beneficial. Do not consume any
medicine on your own without consulting your doctor. If your diarrhea worsens
contact your doctor immediately.

Q: What should I do if I forgot to take a dose of TRISULFOSE DS TABLET?

A: If you forgot to take a dose of TRISULFOSE DS TABLET, take it as soon as you
remember. However, if it is time to take the next dose, skip the missed dose and
take the next one at regular times. Do not take a double dose to compensate the
forgotten dose.

Useful Diagnostic Tests

• Complete blood count