EVERCON 0.5mg Tablet 10's

Introduction About EVERCON 0.5MG TABLET

EVERCON 0.5MG TABLET contains Everolimus which belongs to the group of medicines
called Immunosuppressants. It is used for the management of organ rejection in
transplant patients (organs like kidney or liver). It is also used together with
other medicines, such as ciclosporin for the transplantation of kidney,
tacrolimus for liver transplantation, and corticosteroids. Organ transplant
rejection is when a new organ is transplanted into the body, our body recognizes
it as a foreign element and tries to attack and reject it because it is not
originally part of the body.

Before taking EVERCON 0.5MG TABLET, inform your doctor if you have or ever had
recent major surgery, or if you still have an unhealed wound following surgery,
skin cancer, high cholesterol, or triglycerides, Lapp lactase deficiency or
glucose-galactose malabsor
kidney problems.

EVERCON 0.5MG TABLET is not recommended for use in children and adolescents
(below 18 years of age) and elders (65 years and above). EVERCON 0.5MG TABLET is
generally not recommended for use among pregnant and breastfeeding women. The
most common side effects of taking EVERCON 0.5MG TABLET are nausea, swelling of
the lower legs, ankles, and feet, vomiting, diarrhea, stomach pain, infections,
anemia, headache, anxiety. Contact your physician for advice if any of the
symptoms worsen.

Uses Of EVERCON 0.5MG TABLET

It is used:

• for the management of organ rejection in transplant patients (organs like kidney or liver)
• together with other medicines, such as ciclosporin for the transplantation of kidney, tacrolimus for liver transplantation, and corticosteroids

How EVERCON 0.5MG TABLET Works

EVERCON 0.5MG TABLET works by suppressing the activity of the body's immune
system and managing the rejection of the transplanted organ.

How to use EVERCON 0.5MG TABLET

Take EVERCON 0.5MG TABLET as advised by your physician. Swallow the medicine
with enough water. Do not crush or chew the EVERCON 0.5MG TABLET. The correct
dose and duration will be decided by your physician for you depending on your
age, body weight, and disease condition.

Side Effects Of EVERCON 0.5MG TABLET

Common

• infections (viral, bacterial, and fungal infections, urinary tract infections, upper and lower respiratory tract infections, lung infections, including pneumonia, inflammation of the pharynx, and the common cold)
• anemia (reduced red blood cell count)
• low levels of white blood cells (infection, reduced blood platelet count can lead to bleeding and/or bruising underneath the skin)
• increased level of fats in the blood
• the onset of diabetes (high level of sugar in the blood)
• decreased potassium level in the blood
• anxiety
• problems falling asleep (insomnia)
• headache
• fluid collection in the sac around the heart (if severe it can decrease the heart's ability to pump blood)
• high blood pressure
• venous thrombosis (due to blood clot blockage of a major vein)
• collection of fluid on the lungs and in the chest cavity
• coughing
• breathlessness
• diarrhea
• nausea
• vomiting
• stomach pain
• fever
• accumulation of fluid in the tissues
• abnormal wound healing
• blood poisoning
• cancers and benign tumors
• thrombocytopenic purpura/hemolytic uremic syndrome (kidney damage with low blood platelets and low red blood cell counts, with or without a rash)
• fast heartbeat
• nose bleeds
• decreased numbers of blood cells (symptoms may include weakness, bruising and frequent infections)
• clotting of the blood vessels in the kidney (which may result in graft loss mostly within the first 30 days after kidney transplantation)
• bleeding disorders
• cyst containing lymph fluid
• pain in the mouth or throat
• inflammation of the pancreas
• mouth sores
• acne
• hives (urticaria) and other allergic symptoms (like swelling of the face or throat)
• joint pain, muscle pain
• protein in the urine
• kidney disorders
• impotence
• hernia at the site of surgery

Uncommon

• lymph tissue cancer (lymphoma/post-transplant lymphoproliferative disorder)
• low levels of testosterone
• inflammation of the lungs or liver
• jaundice
• ovarian cysts

Stop taking EVERCON 0.5MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• infections
• inflammation of the lungs
• allergic reactions
• fever and bruising under the skin (red dots, with or without unexplained tiredness, confusion, yellowing of the skin or eyes, and reduced urine output)
• lung or breathing problems (new or worsening cough, shortness of breath, difficulty breathing or wheezing)
• fever, usually feeling unwell, abdominal or chest pain, chills, burning sensation when urinating
• swelling of tongue, lips, face, or throat
• difficulty swallowing
• spontaneous bruising or bleeding
• pain, unusual warmness, swelling, or oozing from the site of surgery

How To Manage Side Effects

!### Diarrhea

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do
not consume any medicine on your own without consulting your physician.

!### Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Avoid
eating oil-rich or spicy foods.

!### Stomach Pain

Try to rest and relax. Eat and drink gradually or try to have lesser and more
frequent meals. Keep a heating pad on your stomach. Contact your physician for
advice if the symptom does not improve.

Warning & Precautions

!### Pregnancy

RiskyEVERCON 0.5MG TABLET should not be given to pregnant women unless the potential
benefit outweighs the potential risk to the fetus. Consult your doctor before
taking it.

!### Breastfeeding

ContraindicatedEVERCON 0.5MG TABLET is not recommended for use in breastfeeding women as it may
pass through breast milk. Consult your doctor before taking it.

!### Kidney

Use with CautionEVERCON 0.5MG TABLET should be taken with caution in patients with kidney
problems. Consult your doctor before taking.

!### Liver

Use with CautionEVERCON 0.5MG TABLET should be taken with caution in patients with liver
problems. Consult your doctor before taking.

!### Allergy

ContraindicatedDo not take EVERCON 0.5MG TABLET if you are allergic to Everolimus or any of the
other ingredients of this medicine.

!### Heart Disease

Use with CautionEVERCON 0.5MG TABLET should be taken with caution in patients with heart
problems. Consult your doctor before taking [GBNKEYWROD].

!### Use In Pediatrics

Consult your doctorThere are no adequate data of the use of [GBNKEYWROD] in children and
adolescents to support its use in patients in these age groups. Consult your
doctor before taking [GBNKEYWROD].

!### Use In Geriatrics

ContraindicatedEVERCON 0.5MG TABLET is generally not recommended for use in elderly patients
(above 65 years of age). Consult your doctor before taking EVERCON 0.5MG TABLET.

Others

Before taking EVERCON 0.5MG TABLET, inform your physician if you:

• have or ever had recent major surgery
• have an unhealed wound following surgery
• need to have vaccination

Interactions

A. Drug-Drug interactions:

Before taking EVERCON 0.5MG TABLET, inform your doctor if you are taking any of
the following medicine:

• medicines used as antibiotics (Ex. rifampicin, rifabutin, clarithromycin, erythromycin, or telithromycin)
• medicines used to manage viral infections (Ex. ritonavir, efavirenz, nevirapine, nelfinavir, indinavir or amprenavir)
• medicines used to manage fungal infections (Ex. voriconazole, fluconazole, ketoconazole or itraconazole)
• medicines used to manage epilepsy (Ex. phenytoin, phenobarbital, or carbamazepine)
• medicines used to manage high blood pressure or heart problems (Ex. verapamil, nicardipine, or diltiazem)
• medicine used to regulate heartbeat (Ex. dronedarone)
• medicines used for lower blood cholesterol (Ex. atorvastatin, pravastatin, or fibrates)
• medicines used to manage acute seizures
• medicines used as a sedative before or during surgery or other medical procedures (Ex. midazolam)
• medicine used to manage acromegaly (Ex. octreotide)
• medicine used to inhibit the growth of abnormal cells (Ex. imatinib)
• herbal medicine used to manage depression (Hypericum perforatum)

B. Drug-Food interactions:

Avoid having grapefruit or grapefruit juice while taking EVERCON 0.5MG TABLET as
it may increase the risk of side effects.

Overdosage:

If you or anyone else accidentally takes too much of EVERCON 0.5MG TABLET,
consult your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Everolimus
Pharmacological Category	:	Immunosuppressants
Therapeutic Indication	:	Prevention of organ rejection in transplant patients
Dosage Forms	:	Tablet

More Information

• Keep EVERCON 0.5MG TABLET out of reach of children
• Store at a room temperature

FAQs About EVERCON 0.5MG TABLET

Q: What for EVERCON 0.5MG TABLET used?

A: EVERCON 0.5MG TABLET is used for the management of organ rejection in
transplant patients (organs like kidney, liver, or heart). It is used together
with other medicines, such as ciclosporin for the transplantation of kidney and
heart, tacrolimus for liver transplantation, and corticosteroids.

Q: How does EVERCON 0.5MG TABLET works?

A: EVERCON 0.5MG TABLET acts by suppressing the activity of the body's immune
system and manages the rejection of the transplanted organ.

Q: What are the common side effects of EVERCON 0.5MG TABLET?

A: The most common side effects of taking EVERCON 0.5MG TABLET are nausea,
vomiting, diarrhea, stomach pain, infections, anemia, headache, anxiety. Contact
your physician for advice if any of the symptoms worsen.

Q: Is it safe to use EVERCON 0.5MG TABLET in elderly patients?

A: EVERCON 0.5MG TABLET is generally not recommended for use in elderly patients
(above 65 years of age). Consult your doctor before taking EVERCON 0.5MG TABLET.

Q: Is there any food to avoid while taking EVERCON 0.5MG TABLET?

A: Avoid having grapefruit or grapefruit juice while taking EVERCON 0.5MG TABLET
as it may increase the risk of side effects. Consult your physician before
taking EVERCON 0.5MG TABLET.

Q: Can I take EVERCON 0.5MG TABLET along with antiepile

A: Antiepile
the efficacy of EVERCON 0.5MG TABLET. Consult your doctor before taking EVERCON
0.5MG TABLET.

Q: Is it safe to use EVERCON 0.5MG TABLET in pregnant and breastfeeding?

A: EVERCON 0.5MG TABLET is generally not recommended for use in pregnant and
breastfeeding women unless considered clearly necessary. Consult your doctor
before taking EVERCON 0.5MG TABLET.

Useful Diagnostic Tests

• Complete Blood Count