Colizole DS 800/160mg Tablet 10'S

Introduction About COLIZOLE DS 800/160MG TABLET

COLIZOLE DS 800/160MG TABLET is a combination of Sulphamethoxazole and
Trimethoprim which belongs to the group of medicines called Antibiotics. It is
used to manage lung infections (pneumonia or Pneumocystis jiroveci pneumonia)
caused by a bacteria called Pneumocystis jirovecii and toxoplasmosis (infection
with the Toxoplasma gondii parasite).

It can also be used to manage urinary tract infections, respiratory tract
infections (such as bronchitis), ear infections (such as otitis media) and an
infection called nocardiosis which can affect the lungs, skin and brain.
COLIZOLE DS 800/160MG TABLET is suitable for use both in adults and in
adolescents (aged 12 years or above).

Take COLIZOLE DS 800/160MG TABLET for the stipulated duration as instructed by
your doctor even if you feel better during the midway of the therapy to achieve
better results. Failing to complete the full course of the therapy or skipping
doses in between the therapy may not result in adequate infection control.

Before taking COLIZOLE DS 800/160MG TABLET inform your doctor if you have any
liver or kidney problems. You must also inform your doctor if you have asthma,
any allergic conditions, genetic disorders, blood-related disorders, folic acid
deficiency, high blood potassium levels or if you are malnourished as a
precaution.

Consult your doctor before taking this medicine if you are pregnant or
breastfeeding. The most common side effects of taking COLIZOLE DS 800/160MG
TABLET are headache, nausea, diarrhea, high blood potassium levels, fungal
infections of the mouth or vagina and skin rashes. Consult your doctor if any of
these side effects troubles you.

Uses Of COLIZOLE DS 800/160MG TABLET

It is used in adults and in adolescents (aged 12 years or above) to manage the
following bacterial infections:

• Lung infections (Ex. Pneumonia or Pneumocystis jiroveci pneumonia) caused by a bacteria called Pneumocystis jirovecii
• Toxoplasmosis (an infection with the Toxoplasma gondii parasite)
• Urinary tract infections
• Respiratory tract infections (Ex. bronchitis)
• Ear infections (Ex. otitis media)
• Nocardiosis (a bacterial infection that affects the lungs, skin and brain)

How COLIZOLE DS 800/160MG TABLET Works

COLIZOLE DS 800/160MG TABLET is a powerful antibiotic. It kills the susce
bacteria by blocking the production of certain essential vitamins (folate) that
are necessary for the bacteria to grow, multiply and survive. Therefore, it
destroys the susce
multiplication within the body which helps in reducing the severity of the
infection.

How to use COLIZOLE DS 800/160MG TABLET

Take COLIZOLE DS 800/160MG TABLET as advised by your physician. Swallow COLIZOLE
DS 800/160MG TABLET with a glass of water. Do not crush or chew the medicine.
COLIZOLE DS 800/160MG TABLET can be taken with or without food.

Your doctor will decide the correct dose and duration of therapy for you
depending on your age, body weight and severity of the infection.

Do not stop taking COLIZOLE DS 800/160MG TABLET once your symptom subsides. It
is important to take COLIZOLE DS 800/160MG TABLET for the stipulated duration as
recommended by your doctor to achieve better results.

Side Effects Of COLIZOLE DS 800/160MG TABLET

Common

• high potassium levels in blood causing abnormal heartbeats
• fungal infection (thrush or candidiasis) of mouth or vagina
• headache, nausea, diarrhoea
• skin rashes

Uncommon

• vomiting

Rare

Stop taking COLIZOLE DS 800/160MG TABLET and contact your doctor immediately if
you experience any of the following side effects:

• severe allergic reactions (such as skin rashes, itching, swelling of the face, lips, tongue or throat causing difficulty in breathing or swallowing, chest pain and fainting)
• severe skin reactions (such as generalised skin redness with pustules accomp
• signs of abnormal WBC count (such as fever, swollen glands, weakness, light-headedness, shortness of breath, bruising with or without skin rash)
• unexpected worsening of cough and shortness of breath

How To Manage Side Effects

!### Diarrhea

Drink plenty of fluids, such as water or fruit juice to keep yourself hydrated.
Consuming ORS can also be beneficial. Do not consume any medicine on your own
without consulting your doctor. If your diarrhea worsens, contact your doctor
immediately.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate your
headache. Consult your doctor if your headache worsens.

!### Nausea And Vomiting

Take COLIZOLE DS 800/160MG TABLET with, or just after meals. Stick to simple
meals. Avoid eating oil-rich or spicy foods. Please consult your doctor
immediately if you experience severe nausea and vomiting.

Warning & Precautions

!### Pregnancy

Use with CautionCOLIZOLE DS 800/160MG TABLET should be used with caution in pregnant women.
Therefore, consult your doctor for advice before taking it.

!### Breastfeeding

Use with CautionCOLIZOLE DS 800/160MG TABLET should be used with caution in breastfeeding women.
Therefore, consult your doctor for advice before taking it.

!### Driving and Using Machines

Use with CautionDo not drive or operate any heavy tools or machines if your ability is affected
by COLIZOLE DS 800/160MG TABLET.

!### Alcohol

Consult your doctorAvoid consum

!### Kidney

Consult your doctorCOLIZOLE DS 800/160MG TABLET is not recommended for use in patients with severe
kidney problems. It should be used with caution in patients with other kidney
problems. Therefore, consult your doctor before taking it.

!### Liver

ContraindicatedCOLIZOLE DS 800/160MG TABLET is not recommended for use in patients with severe
liver problems. Therefore, consult your doctor before taking it.

!### Allergy

ContraindicatedDo not take COLIZOLE DS 800/160MG TABLET if you are allergic to
Sulphamethoxazole, trimethoprim, sulphonamide medicines (such as gliclazide,
glibenclamide) or to thiazide diuretics (such as Bendroflumethiazide).

!### Lungs

Use with CautionCOLIZOLE DS 800/160MG TABLET should be used with caution in patients with
asthma. Therefore, consult your doctor before taking it.

!### Use In Pediatrics

ContraindicatedCOLIZOLE DS 800/160MG TABLET is not recommended for use in children and
adolescents (aged below 12 years). However, consult your doctor for advice
before taking it.

!### Use In Geriatrics

Use with CautionCOLIZOLE DS 800/160MG TABLET should be used with caution in elderly patients.
Therefore, consult your doctor for advice before taking it.

Others

COLIZOLE DS 800/160MG TABLET is not recommended for use if you:

• ever had bleeding problems (such as thrombocytopenia)
• have porphyria (a rare blood disorder)

Before taking COLIZOLE DS 800/160MG TABLET, consult your doctor if you:

• have any allergic conditions (such as watery eyes, itchy nose, repeated sneezing)
• have anemia or vitamin B9 (folic acid) deficiency
• have G6PD deficiency (a genetic disorder that affect metabolism)
• have phenylketonuria (build-up of an amino acid called phenylal
• are underweight or malnourished
• have high blood potassium levels
• have very low RBC, WBC and platelet counts in blood

Interactions

A. Drug-Drug Interactions:

Before taking COLIZOLE DS 800/160MG TABLET, inform your doctor if you are taking
any of the following medicines such as:

• diuretics (medicines used to remove excess water from the body) such as furosemide, hydrochlorothiazide
• pyrimethamine (a medicine used to manage malaria)
• medicines used for blood thinning (such as warfarin)
• phenytoin (a medicine used to manage epilepsy)
• medicines used to manage diabetes (such as glibenclamide, glipizide, tolbutamide or repaglinide)
• rifampicin (an antibiotic used to manage tuberculosis)
• medicines used to manage heart problems (such as digoxin or procainamide)
• amantadine (a medicine used to manage Parkinson’s disease)
• medicines used to manage HIV infections (such as zidovudine or lamivudine)
• medicines that can increase the amount of potassium in blood, such as potassium-sparging diuretics (Ex. spironolactone, acetazolamide), certain steroids (like prednisolone) or ACE inhibitors (Ex. captopril, enalapril, lisinopril)
• medicines used to suppress immune function and to manage graft rejection (such as ciclosporin, azathioprine)
• methotrexate (a medicine used to manage certain cancers or joint pain)
• folinic acid (a type of vitamin B9 supplement)
• contrace

B. Drug-Food Interaction:

COLIZOLE DS 800/160MG TABLET is preferably taken with meals to avoid unwanted
stomach problems. However, it can also be taken on an empty stomach. Avoid
consuming foods rich in potassium while taking this medicine.

Overdosage:

If you or anyone else accidentally took more COLIZOLE DS 800/160MG TABLET,
consult your doctor immediately or visit the nearby hospital. Symptoms of
overdosage might include nausea, vomiting, dizziness and confusion.

Synopsis

Drug	:	Sulphamethoxazole, Trimethoprim
Pharmacological Category	:	Sulphonamides, Diaminopyrimidine
Therapeutic Indication	:	Bacterial Infections
Dosage Forms	:	Tablet, Syrup, Suspension, Injection, Infusion, Eye drops

More Information

• Keep COLIZOLE DS 800/160MG TABLET out of reach of children
• Store COLIZOLE DS 800/160MG TABLET at room temperature

FAQs About COLIZOLE DS 800/160MG TABLET

Q: What is the use of COLIZOLE DS 800/160MG TABLET?

A: COLIZOLE DS 800/160MG TABLET is used to manage severe bacterial infections
including lung infections, toxoplasmosis (infection with the Toxoplasma gondii
parasite), urinary tract infections, respiratory tract infections (such as
bronchitis), ear infections (such as otitis media) and an infection called
nocardiosis which can affect the lungs, skin and brain.

Q: How COLIZOLE DS 800/160MG TABLET works in my body?

A: COLIZOLE DS 800/160MG TABLET is a powerful antibiotic. It kills the
susce
(folate) that is necessary for the bacteria to grow, multiply and survive.
Therefore, it destroys the susce
and multiplication within the body which helps in reducing the severity of the
infection.

Q: How should I take COLIZOLE DS 800/160MG TABLET?

A: Take COLIZOLE DS 800/160MG TABLET as advised by your physician. It can be
taken with or without food. Swallow the medicine with a glass of water. Do not
crush or chew the medicine.

Q: For how long should I take COLIZOLE DS 800/160MG TABLET?

A: TakeCOLIZOLE DS 800/160MG TABLET for the stipulated duration as prescribed by
your doctor. Do not skip the medicine or stop taking it on your own as it can
cause the infection to reappear.

Q: Can COLIZOLE DS 800/160MG TABLET be given to pregnant women?

A: COLIZOLE DS 800/160MG TABLET should be used with caution in pregnant women.
Therefore, consult your doctor for advice before taking it.

Q: What precautions should I follow while taking COLIZOLE DS 800/160MG
TABLET?

A: Before taking COLIZOLE DS 800/160MG TABLET inform your doctor if you have any
liver or kidney problems. You must also inform your doctor if you have asthma,
any allergic conditions, genetic disorders, blood-related disorders or if you
are malnourished as a precaution. Consult your doctor before taking this
medicine if you are pregnant or breastfeeding. Regularly visit your doctor for
check-up and perform all medical tests recommended by your doctor without fail.
Take COLIZOLE DS 800/160MG TABLET for the stipulated duration recommended by
your doctor to achieve better results. Failing to do so may cause the symptom to
re-occur.

Q: What are the common side effects of taking COLIZOLE DS 800/160MG TABLET?

A: The most common side effects of taking COLIZOLE DS 800/160MG TABLET are
headache, nausea, diarrhea, high blood potassium levels, fungal infections of
mouth or vagina and skin rashes. Consult your doctor if any of these side
effects troubles you.

Q: Can I stop taking COLIZOLE DS 800/160MG TABLET once my symptoms subside?

A: Do not stop taking this medicine once your symptom subsides. It is important
to take the full course of COLIZOLE DS 800/160MG TABLET to achieve better
results. Failing to complete the full course of the therapy or skipping doses in
between the therapy may not result in adequate infection control. It may also
cause your symptoms to reappear.

Q: Can the use of COLIZOLE DS 800/160MG TABLET cause diarrhea?

A: COLIZOLE DS 800/160MG TABLET may cause diarrhea in some individuals. If you
experience diarrhea, drink plenty of fluids, such as water or fruit juice to
keep yourself hydrated. Consuming ORS can also be beneficial. Do not consume any
medicine on your own without consulting your doctor. If your diarrhea worsens
contact your doctor immediately.

Q: What should I do if I forgot to take a dose of COLIZOLE DS 800/160MG
TABLET?

A: If you forgot to take a dose of COLIZOLE DS 800/160MG TABLET, take it as soon
as you remember. However, if it is time to take the next dose, skip the missed
dose and take the next one at regular times. Do not take a double dose to
compensate the forgotten dose.

Useful Diagnostic Tests

• Complete blood count