BRINZOMA Eye Drops 5ml

Introduction About BRINZOMA EYE DROPS

BRINZOMA EYE DROPS contains Brinzolamide which belongs to the group of medicines
called Ophthamic anti-glaucoma agents. It is used to manage glaucoma. Glaucoma
is group of eye condition that damages the o
responsible for proper vision). It is characterized by increased pressure within
the eyes caused due to impaired secretion or drainage of fluids (aqueous humour)
within the eyes. During the intial days, glaucoma may remain asymptomatic. At
later stages, it may cause eye pain or redness, halos around the light, severe
headache or blurred vision.

Brinzolamide reduces pressure within the eye. It works by blocking the action of
an enzyme called carbonic anhydrase, that causes pressure within the eye to
raise. As a result, it decreases the elevated pressure within the eye and
provides relief from unpleasant symptoms (such as eye pain, headache, or blurred
vision).

BRINZOMA EYE DROPS is not recommended for use in patients with kidney problems.
It should be used with caution in patients with liver problems, dry eyes, or
corneal problems. BRINZOMA EYE DROPS is generally not recommended for use in
pregnant and in breastfeeding women unless considered necessary by the
physician. It is also not suitable for use in children and adolescents.

If you wear soft contact lenses, remove the lens before applying BRINZOMA EYE
DROPS and wait for at least 15 minutes before reinsertion. Do not stop using
BRINZOMA EYE DROPS without consulting your doctor, because premature
discontinuation can further increase the pressure within the eye. The most
common side effects of BRINZOMA EYE DROPS are eye irritation, blurred vision,
and bitter taste in mouth. Consult your doctor if any of the side effect bothers
you.

Uses Of BRINZOMA EYE DROPS

• Manage glaucoma (increased pressure within the eye)

How BRINZOMA EYE DROPS Works

BRINZOMA EYE DROPS effectively reduces pressure within the eye where
brinzolamide acts by blocking the action of an enzyme called carbonic anhydrase,
which is responsible for increasing the production of aqueous humour (fluid in
the eyes) and subsequent increase in the intraocular pressure (pressure within
the eye). Blockade of carbonic anhydrase decreases the production of aqueous
humour and reduces the elevated pressure within the eye which therefore provides
relief from unpleasant symptoms (such as eye pain, headache or blurred vision).

How to use BRINZOMA EYE DROPS

Use BRINZOMA EYE DROPS as advised by your physician. It is for ophthalmic use
only. Do not swallow. Wash your hands before and after application. Tilt your
head slightly and gently pull the lower eyelid downwards. Instil few drops of
the medicine into the affected eye(s). Close your eyes and press the corner of
your eye with your finger for a minute. Do not touch the tip of the dropper with
your eye or other body surface to avoid contamination.

Apply applying BRINZOMA EYE DROPS, leave a time gap of at least 5 minutes before
applying other eye drops or ointment. If you wear soft contact lenses, remove
the lens before applying BRINZOMA EYE DROPS and wait for at least 15 minutes
before reinsertion.

Your doctor will decide the correct dose and duration of therapy for you
depending upon the severity of the disease condition. Do not stop using BRINZOMA
EYE DROPS without consulting your doctor, as the pressure within the eye may
raise once again and become uncontrollable.

Side Effects Of BRINZOMA EYE DROPS

Common

• bitter or unusual taste
• eye irritation, blurred vision

Uncommon

• red and flaky skin, skin rash with raised bumps, tight skin
• abnormal heart rate
• shortness of breath or chest tightness with wheezing after physical exercise
• dizziness, headache
• sensation of tingling or pins and needles in the hands or feet
• tiredness
• signs of sinus problems (such as difficulty in breathing through the nose and pain in face)
• mucus builds up behind nose or throat
• abnormal or decreased sensation in mouth
• allergic symptoms (nose bleeds, runny nose, or sneezing)
• dryness of mouth

Rare

• difficulty in sleeping or drowsiness
• increased pressure within the eye
• hair loss
• generalised weakness, feeling jittery or irritable
• memory loss
• ringing in ears

Stop using BRINZOMA EYE DROPS and contact your immediately if you experience any
of the following side effects:

• eye problems (eye pain or redness, blurred vision, increased tear production with possible increased sensitivity to light, eye irritation)
• signs of decreased oxygen level in the body (such as difficulty in breathing, increase in heart rate with sweating, wheezing or crackling sounds or having blue lips, pale or grey skin)
• signs of angina (such as heavy or pressing sensation on the chest with severe sharp pain in the chest)
• severe allergic reactions (such as skin rash, swelling of the eye, eyelids, face, lips, tongue, hands or throat leading to difficulty in breathing)

How To Manage Side Effects

!### Eye irritation Or Itching

Wash your eyes with plain cold water. Place an ice pack on your eye to ease the
irritation. Avoid straining your eyes by looking at mobile phones, laptops, or
television. Wear protective eyeglasses while going outdoors.

!### Eye pain Or Sensitivity

Close your eyes and relax. Do not strain your eyes by looking at mobile phones,
laptops, or television. Avoid driving or operating any heavy tools or machines
while your vision is blur. Consult your doctor if you experience blurred vision
for a prolonged period.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate your
headache. Consult your doctor if your headache worsens.

Warning & Precautions

!### Pregnancy

Monitoring requiredBRINZOMA EYE DROPS is generally not recommended for use in pregnant women unless
considered necessary by the physician. Therefore, consult your doctor before
using. Women of childbearing age should use proper contrace
pregnancy while undergoing therapy with BRINZOMA EYE DROPS.

!### Breastfeeding

Monitoring requiredBRINZOMA EYE DROPS is generally not recommended for use in breastfeeding women
unless considered necessary by the physician. Therefore, consult your doctor
before using.

!### Driving and Using Machines

Use with CautionDo not drive or operate any heavy tools or machines if you experience dizziness
or blurred vision after using BRINZOMA EYE DROPS.

!### Kidney

Consult your doctorBRINZOMA EYE DROPS is not recommended for patients with severe kidney diseases.
It should be used with caution in patients with other minor kidney problems.
Therefore, consult your doctor before using.

!### Liver

Use with CautionBRINZOMA EYE DROPS should be used with caution in patients with liver problems.
Therefore, consult your doctor before using.

!### Allergy

ContraindicatedDo not use BRINZOMA EYE DROPS if you are allergic to Brinzolamide.

!### Use In Pediatrics

ContraindicatedBRINZOMA EYE DROPS is generally not recommended for use in children and
adolescents (below 18 years). Therefore, consult your doctor before using.

!### Use In Geriatrics

Use with Caution[GBNKEYWORD[ should be used with caution in elderly patients. Therefore, consult
your doctor before using.

Others

BRINZOMA EYE DROPS is not recommended for use if you:

• have hyperchloremic acidosis (a condition where there it too much of acidity in blood)

Before using BRINZOMA EYE DROPS, inform your doctor if you:

• have dry eyes or problems in your cornea
• have pseudo exfoliative glaucoma (an eye condition caused when the eye’s drainage system is clogged by flaky deposit materials)
• have narrow angle glaucoma (a type of rapid increase in pressure within the eye)

Interactions

A. Drug-Drug interactions:

Before using BRINZOMA EYE DROPS, inform your doctor if you are taking any of the
following medicines such as:

• other carbonic anhydrase inhibitors (used to manage glaucoma) Ex. acetazolamide and dorzolamide
• sulphonamides (used to manage bacterial infections) Ex. sulfamethoxazole, sulfasalazine

Overdosage:

If you or anyone else accidentally used more BRINZOMA EYE DROPS, rinse your eye
with warm water. If still irritation persists, consult your doctor.

Synopsis

Drug	:	Brinzolamide
Pharmacological Category	:	Carbonic anhydrase inhibitors
Therapeutic Indication	:	Glaucoma
Dosage Forms	:	Eye drops, Ophthalmic suspension

More Information

• Keep BRINZOMA EYE DROPS out of reach of children
• Store at room temperature

FAQs About BRINZOMA EYE DROPS

Q: Can the use of BRINZOMA EYE DROPS cause blurred vision?

A: Yes. BRINZOMA EYE DROPS may cause blurred vision after application. If your
vision becomes blur, close your eyes for some time and rest. Do not strain your
eyes by looking at mobile phones, laptops, or television. Avoid driving or
operating any heavy tools or machines while your vision is blur. Consult your
doctor if you experience blurred vision for a prolonged period.

Q: Is it normal to experience headache after using BRINZOMA EYE DROPS?

A: Yes. The use of BRINZOMA EYE DROPS can cause headache in some indivduals. It
is one of the uncommon side effects of BRINZOMA EYE DROPS. It happens when too
much of the medicines enters your blood. If you experience headache, rest and
relax. Applying a pain-relieving balm on your forehead can be beneficial. Do not
stress yourself too much. Avoid consuming excessive alcohol. Consult your doctor
if your headache worsens.

Q: Can I use other eye medicines while using BRINZOMA EYE DROPS?

A: Yes. You can use other eye medicines while undergoing therapy with BRINZOMA
EYE DROPS. But make sure to leave a time gap of at least 5 minutes before
applying other eye drops or ointment.

Q: Who should avoid using BRINZOMA EYE DROPS?

A: BRINZOMA EYE DROPS should be avoided in patients with severe kidney problems.
It should be used with caution in patients with liver problems or other problems
in eye such as eye dryness, corneal problems or narrow-angle glaucoma. It is
also not suitable for use in patients having too much acidity in blood
(hyperchloremic acidosis). Patients aged below 18 years must consult your doctor
before using BRINZOMA EYE DROPS.

Q: How to use BRINZOMA EYE DROPS?

A: Use BRINZOMA EYE DROPS as advised by your physician. It is for ophthalmic use
only. Instil few drops of the medicine into the affected eye(s). Close your eyes
and press the corner of your eye with your finger for a minute. If you wear soft
contact lenses, remove the lens before applying BRINZOMA EYE DROPS and wait for
at least 15 minutes before reinsertion. Do not stop using BRINZOMA EYE DROPS
without consulting your doctor, as the pressure within the eye may raise once
again and become uncontrollable.

Q: What is the use of BRINZOMA EYE DROPS?

A: BRINZOMA EYE DROPS is a prescri
adult patients. It effectively reduces pressure within the eye by blocking the
action of an enzyme called carbonic anhydrase, that causes pressure within the
eye to raise.

Q: How long does it take for [GBNKRYWORD] to work?

A: It may take about 1 to 4 weeks for BRINZOMA EYE DROPS to show the results.
Therefore, continue to use BRINZOMA EYE DROPS as prescribed by your physician.

Q: Is BRINZOMA EYE DROPS same as timolol?

A: No. BRINZOMA EYE DROPS contains Brinzolamide which is a carbonic anhydrase
inhibitor. It acts by blocking the action of an enzyme called carbonic
anhydrase, that causes pressure within the eye to raise. Whereas timolol is a
beta-blocker which acts by reducing intraocular pressure by blocking the
beta-receptors of the eye. Although both are used to manage glaucoma, they are
not the same.

Q: What are the side effects of BRINZOMA EYE DROPS?

A: The most common side effects of BRINZOMA EYE DROPS are eye irritation,
blurred vision, and bitter taste in mouth. Sometimes people may also experience
systemic side effects like headache, dizziness, fast heart rate or shortness of
breath. Consult your doctor if any of the side effect bothers you.

Q: Can I use BRINZOMA EYE DROPS while wearing contact lenses?

A: If you wear soft contact lenses, remove the lens before applying BRINZOMA EYE
DROPS and wait for at least 15 minutes before reinsertion. This is because
BRINZOMA EYE DROPS contains benzalkonium chloride which may interact with your
contact lens and make your lens to discolour.

Q: Can I stop using BRINZOMA EYE DROPS without consulting my doctor?

A: Do not stop using BRINZOMA EYE DROPS without consulting your doctor, as the
pressure within the eye may raise once again and become uncontrollable. If you
think that you are feeling better or if you wish to stop using BRINZOMA EYE
DROPS, contact your doctor for advice. Your doctor will check your condition and
gradually withdraw the dose.

Q: Is BRINZOMA EYE DROPS safe for pregnant and breastfeeding women?

A: BRINZOMA EYE DROPS is generally not recommended for use in pregnant women
unless considered necessary by the physician. Therefore, consult your doctor
before using. Women of childbearing age should use proper contrace
to avoid pregnancy while undergoing therapy with BRINZOMA EYE DROPS.

Q: Can I drive or ride a bike after using BRINZOMA EYE DROPS?

A: Do not drive if you feel dizzy or experience blurred vision after using
BRINZOMA EYE DROPS. It also effects the ability to perform tasks that need
alertness or coordination so be cautious while driving.

Q: What if I miss a dose of BRINZOMA EYE DROPS?

A: If you missed a dose of BRINZOMA EYE DROPS, apply it as soon as you remember.
However, if it is time for next dose, skip the missed dose and use the regular
dose. Do not use a double dose to compensate the missed dose.

Q: Is BRINZOMA EYE DROPS and brimonidine same?

A: No. BRINZOMA EYE DROPS contains Brinzolamide which is a carbonic anhydrase
inhibitor. It acts by blocking the action of an enzyme called carbonic
anhydrase, that causes pressure within the eye to raise. Whereas brimonidine is
an alpha-agonist used to manage narrow-angle glaucoma. It works by activating
the alpha receptors of the eye. Although both are used to manage glaucoma, they
are not the same.