LOCARP 2% Eye Drops 1's

Introduction About LOCARP 2% EYE DROPS

LOCARP 2% EYE DROPS contains Pilocarpine which belongs to the group of medicines
called Cholinergic agonists. It is used to manage certain types of glaucoma (a
rise in the pressure within the eye) and to reverse the effect of medicines that
cause the pupil of the eye to enlarge.

Your doctor will ask you to remove your contact lenses prior to the
administration of LOCARP 2% EYE DROPS and will regularly check your eyes before
and during management, particularly if you have had any eye disorders.

LOCARP 2% EYE DROPS is not recommended for use in patients having some
particular eye conditions where you can't let the pupil of the eye to constrict
(Ex. inflammation of the iris, some types of glaucoma) or if you wear soft
contact lenses. Before using LOCARP 2% EYE DROPS, inform your doctor if you have
any heart, lung, kidney, stomach or eye problems.

LOCARP 2% EYE DROPS should be used with caution in pregnant and breast feeding
women. In children, the doctor will prescribe the right dose of LOCARP 2% EYE
DROPS depending on how they respond to management.

The most common side effects of LOCARP 2% EYE DROPS are eye itching, paining,
burning, swollen eyelid, temporary blurred vision, headache, etc. See your
doctor if any of the symptoms get worse.

Uses Of LOCARP 2% EYE DROPS

Used to:

• Manage certain types of glaucoma
• Reverse the effect of medicines that cause the pupil of the eye to enlarge

How LOCARP 2% EYE DROPS Works

LOCARP 2% EYE DROPS affects the eye muscles causing the pupil of the eye to get
smaller. It also reduces the pressure within the eyeball by decreasing the
production of aqueous humor (fluid in the eye).

How to use LOCARP 2% EYE DROPS

Always use LOCARP 2% EYE DROPS as directed by your physician. It is for
ophthalmic use only. Wash your hands thoroughly. Pull your lower eyelid slowly
and instill one or two drops of LOCARP 2% EYE DROPS inside the lower eyelid.
Close your eyes and gently press on the inner corner of your eyelid for 1 minute
to manage the drainage of the solution into your nose and throat.

If needed, repeat the same for the other eye. Correct dose and duration will be
determined by your doctor depending upon your age, body weight and health
condition. Do not stop using LOCARP 2% EYE DROPS unless your doctor advises you
to stop.

Side Effects Of LOCARP 2% EYE DROPS

Common

• itching, smarting and burning sensation around the eye
• urticaria (red skin rash with itching)
• swelling, redness or pain of the eyelid
• swollen front part of the eye (conjunctiva)
• temporarily blurred vision and short sightedness
• difficulty seeing in poor light
• enlarged of the veins in the eye
• headache and brow ache (particularly in young patients at the start of management)
• bleeding in forepart of the eye
• detached retina (the inner surface of the eye)

Rare

• change in blood pressure or heartbeat
• shortness of breath
• excessive tear secretion

Stop using LOCARP 2% EYE DROPS and contact your doctor immediately if you
experience any of the following side effects:

• increased sweating
• muscle shaking
• nausea, vomiting, diarrhea
• trouble breathing or wheezing
• watering of the mouth

How To Manage Side Effects

Eye itching or burning:

Close your eyes and relax for some time. Place an ice pack on the eyes for few
minutes. Avoid looking at mobile phone, laptop or any other light sources which
might irritate your eyes. If symptom persists, contact your doctor.

Nausea or vomiting:

Stick to simple meals. Try to Avoid oil rich or spicy foods, sugary snacks and
drinks. Try to drink liquid slowly along with your meals or in between meals. If
symptom persists, contact your doctor.

Headache:

Apply hot or cold-water bag on your head. Try to take rest in a quiet and dark
room. Drink tea or coffee. Massage on scalp or head with mild pressure. If
symptom persists, contact your doctor.

Diarrhea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do
not consume any medicine on your own without consulting your doctor. If symptom
persists, contact your doctor.

Warning & Precautions

!### Pregnancy

LOCARP 2% EYE DROPS should be used with caution in women who are pregnant or
planning to have baby. Consult your doctor before using it.

!### Breastfeeding

LOCARP 2% EYE DROPS should be used with caution in breastfeeding women. Consult
your doctor before using it.

!### Driving and Using Machines

Do not drive or operate any machines if you have problems seeing well at night
or blurred vision after taking LOCARP 2% EYE DROPS.

!### Alcohol

Avoid consum

!### Allergy

Do not use LOCARP 2% EYE DROPS you are allergic to Pilocarpine or any of the
other ingredients of this medicine.

!### Lungs

LOCARP 2% EYE DROPS should be used with caution in patients having asthma.
Consult your doctor for advice.

!### Heart Disease

LOCARP 2% EYE DROPS should be used with caution in patients having heart
problems or high blood pressure. Consult your doctor for advice.

Others

LOCARP 2% EYE DROPS is not recommended for use if you:

• have any eye disorders where the constriction of the pupil should be avoided (Ex. inflammation of the iris, anterior uveitis, narrow angle glaucoma or secondary glaucoma)
• are wearing soft contact lenses

Before taking LOCARP 2% EYE DROPS, inform your doctor if you:

• have stomach ulcers
• have trouble passing urine
• have Parkinson’s disease
• have any other eye conditions

Use in Pediatrics:

In children, the doctor will prescribe the right dose of LOCARP 2% EYE DROPS
depending on how they respond to> management. Consult your child’s doctor for
advice.

Interactions

A. Drug - Drug interactions:

Before using LOCARP 2% EYE DROPS, inform your doctor if you are taking any of
the following medicines:

• medicines used to reduce pain or inflammation (Ex. prednisolone, clobetasol)
• medicines used to inhibit muscle contractions (Ex. neostigmine, physostigmine)
• medicines used to manage allergies (Ex. naphazoline, olopatadine)
• pethidine (used to manage pain)
• medicines used to manage depression (Ex. amitriptyline, fluoxetine, sertraline)
• other medicines used to make pupils smaller (Ex. phospholine iodide, carbachol)
• medicines used to enlarge your pupil (Ex. atropine, phenylephrine)
• medicines used to manage Parkinson’s disease (Ex. procyclidine, trihexyphenidyl)
• chlorpromazine (used to manage mental illness)
• orphenadrine (medicine used to relieve pain from sprains, strains or muscle injury)
• guanethidine (used to lower high blood pressure)

Overdosage:

If you or anyone else accidentally used too much of LOCARP 2% EYE DROPS, consult
your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Pilocarpine
Pharmacological Category	:	Cholinergic drugs
Therapeutic Indication	:	Glaucoma, Miosis induction
Dosage Forms	:	Tablet, Eye drops, Ophthalmic solution, Injection

More Information

• Keep LOCARP 2% EYE DROPS out of reach of children
• Store below 25°C away from the light

FAQs About LOCARP 2% EYE DROPS

Can I use LOCARP 2% EYE DROPS if I wear contact lenses?

Do not use LOCARP 2% EYE DROPS if you wear soft contact lenses. Your doctor will
ask you to remove your contact lenses before using this medicine. There is no
information on the effect of LOCARP 2% EYE DROPS on contact lenses. Therefore,
do not wear your contact lenses until the effects of the medicine have
completely worn off.

What if I accidentally swallow LOCARP 2% EYE DROPS?

LOCARP 2% EYE DROPS is for external use only. If you have swallowed or you
suspect someone else has swallowed any of this medicine, contact your doctor or
go to the nearest hospital at once. If possible, take the container with you,
even if empty.

What if I miss a dose of LOCARP 2% EYE DROPS?

If you miss a dose of LOCARP 2% EYE DROPS, take it as soon as you remember.
However, skip that dose if the time for the next dose is closer. Do not take
LOCARP 2% EYE DROPS two times to make up for the missed dose.

Can I stop using LOCARP 2% EYE DROPS without consulting a doctor?

You should keep using LOCARP 2% EYE DROPS for as long as your doctor has asked.
Your management is helping your condition, even if you have not noticed any
improvement. If you want to stop your management, your doctor will advise you
how to do this.

Can LOCARP 2% EYE DROPS affect my eyesight?

With long term use of LOCARP 2% EYE DROPS, it is possible that the lens of your
eye may change shape resulting in changes to your eyesight. Consult your doctor
if you experience any trouble to your eyesight.

Useful Diagnostic Tests

• Ophthalmoscopy