Berab 2.5Iu Injection 0.5ml

Introduction About BERAB 2.5IU INJECTION

BERAB 2.5IU INJECTION is used to reduce the risk of acquiring Rabies infection
prior to exposure to Rabies virus or after exposure. It contains Rabies Antigen
(inactivated Rabies vero cells) which belongs to the group of medicines called
Vaccines.

Rabies is an infection that can be transmitted when a person is bitten,
scratched or even just licked by an infected

BERAB 2.5IU INJECTION is not recommended for use if you have an acute illness
with a high fever. BERAB 2.5IU INJECTION should be used with caution in patients
who has history of allergy (such as asthma, hay fever). Consult your doctor
before receiving it.

BERAB 2.5IU INJECTION can be used in pregnant and breast-feeding women who have
had or are likely to have contact with the virus and used for pre-exposure
prophylaxis. Consult your doctor before receiving it.

The most common side effects of receiving BERAB 2.5IU INJECTION are headache,
dizziness, rash, hives, general discomfort, fatigue, weakness and fever. Contact
your doctor if any of the symptoms worsen.

Uses Of BERAB 2.5IU INJECTION

• To avoid rabies infection

How BERAB 2.5IU INJECTION Works

BERAB 2.5IU INJECTION contains inactivated rabies vero cells which works by
introducing a killed version of the rabies virus into the body. Since the virus
is inactivated, it can't cause the disease, but it can still stimulate the
immune system. The body recognizes the virus as foreign and produces antibodies
against it. These antibodies stay in the body, so if you are ever exposed to the
actual rabies virus, your immune system can quickly fight it off, preventing the
disease from developing.

How to use BERAB 2.5IU INJECTION

BERAB 2.5IU INJECTION will be given to you only by a doctor or a nurse into a
muscle as an intramuscular injection (usually in the upper arm or in small
children, into the muscle of the thigh). Your doctor will decide the correct
dose and duration for you depending upon your age, body weight, previous
vaccination status and disease condition. Do not administer the medicine into
the buttocks, under the skin or into a blood vessel.

Side Effects Of BERAB 2.5IU INJECTION

Common

• headache, dizziness
• rash, hives
• general discomfort
• fatigue, weakness
• fever
• swollen glands
• decreased appetite
• nausea, vomiting, diarrhoea, stomach pain
• muscle pain, joint pain
• pain, redness, swelling, itching or bruising at the site of injection
• hardness of the skin at the site of injection

Rare

• tingling sensations
• sweating, chills

Stop receiving BERAB 2.5IU INJECTION and contact your doctor if you experience
any of the following side effects:

• signs of anaphylactic reactions (serious allergic reactions) such as shock (severe drop of blood pressure), itching, skin rash, swelling of face and/or neck, breathing difficulties, bluish discoloration of the tongue or lips, low blood pressure, rapid heart rate, weak pulse, skin coldness, dizziness and fainting

How To Manage Side Effects

!### Diarrhea

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated.
Do not take any medicine on your own to manage diarrhoea. Contact your doctor if
your diarrhoea did not improve.

!### Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any machines
while you are feeling dizzy. Contact your doctor if your dizziness did not
improve.

Headache

Rest and relax. Drink plenty of fluids such as water or ORS (Oral Rehydrating
Solution) and apply a pain-relieving balm on the head if necessary. Contact your
doctor if your headache did not improve.

!### Nausea And Vomiting

Receive BERAB 2.5IU INJECTION, with or just after a meal. Stick to simple meals.
Avoid eating oily or spicy food. Contact your doctor if your nausea and vomiting
did not improve.

!### Skin rash Or Itching

Avoid hot baths because hot water can irritate your skin further. Do not scratch
the affected area. Use sunscreen and wear protective clothing while going
outside. Use unscented moisturizers to soothe and hydrate the affected area.
Contact your doctor if the rashes worsen.

!### Stomach Pain

Try to have smaller meals but take them frequently. Keep a heating pad on your
stomach. Do not self-manage and contact your doctor if the stomach pain did not
improve.

Warning & Precautions

!### Pregnancy

Consult your doctorBERAB 2.5IU INJECTION can be used for pre-exposure prophylaxis in pregnant women
who have had or are likely to have contact with infected
consult your doctor before receiving it.

!### Breastfeeding

Consult your doctorBERAB 2.5IU INJECTION can be used for pre-exposure prophylaxis in breastfeeding
women who have had or are likely to have contact with infected
consult your doctor before receiving it.

!### Allergy

ContraindicatedBERAB 2.5IU INJECTION is not recommended for use if you are allergic to the
rabies antigen or beta propiolactone or any of the other ingredients of this
medicine.

!### Lungs

Use with CautionBERAB 2.5IU INJECTION should be used with caution in patients who has a history
of allergy (such as asthma). Consult your doctor before receiving BERAB 2.5IU
INJECTION.

!### Use In Pediatrics

Consult your doctorBERAB 2.5IU INJECTION can be used in children and adolescents (aged below 18
years) under medical supervision. It should be used with caution in children
(aged below 1 year). Therefore, consult your doctor before receiving it.

Others

BERAB 2.5IU INJECTION is not recommended for use if you:

• have an acute illness with a high fever that requires management

Before receiving BERAB 2.5IU INJECTION, inform your doctor if you:

• have history of any other reactions to the vaccine
• have any blood disorders that makes you bruise or bleed easily such as haemophilia or thrombocytopenia
• have poor immunity status
• have/has a severe allergy to egg or egg products or to polygeline, latex
• have/has a severe allergy to the antibiotics like neomycin, chlortetracycline or amphotericin B
• fainted with a previous injection of BERAB 2.5IU INJECTION
• has a history of allergies (such as hay fever)

Interactions

A. Drug-Drug Interactions:

Before receiving BERAB 2.5IU INJECTION, inform your doctor, if you are taking
any of the following medicine:

• immunosuppressants (medicines that lower the body’s immune responses) such as corticosteroids Ex. dexamethasone, beclomethasone

Overdosage:

BERAB 2.5IU INJECTION will be given to you only by a doctor or nurse in a
hospital and so it is unlikely to receive an overdose. However, if you
experience any unusual symptoms, consult your doctor immediately or visit the
nearby hospital.

Synopsis

Drug	:	Rabies Vaccine
Pharmacological Category	:	Vaccine
Therapeutic Indication	:	Rabies Prophylaxis
Dosage Forms	:	Injection

More Information

Storage

• Keep BERAB 2.5IU INJECTION out of the sight and reach of children
• Store BERAB 2.5IU INJECTION in a refrigerator (at 2-8°C).  Do not freeze

FAQs About BERAB 2.5IU INJECTION

Q: Can I take other vaccines with BERAB 2.5IU INJECTION?

A: BERAB 2.5IU INJECTION can be given at the same time as other inactivated
vaccines. A different injection site will be used for each type of vaccine.
Consult your doctor before receiving BERAB 2.5IU INJECTION.

Q: Can I receive BERAB 2.5IU INJECTION with fever?

A: BERAB 2.5IU INJECTION is generally not recommended for use in people who are
ill, with a high temperature or acute infection, the vaccination will be
postponed until you or your child have recovered. Your doctor may still decide
to give the vaccine even if this applies to you or your child. This is because
rabies is a serious disease.

Q: What side effects are seen with BERAB 2.5IU INJECTION?

A: The most common side effects of receiving BERAB 2.5IU INJECTION are headache,
dizziness, rash, hives, general discomfort, fatigue, weakness and fever. Contact
your doctor if any of the symptoms worsen.

Q: Who should avoid using BERAB 2.5IU INJECTION?

A: BERAB 2.5IU INJECTION is not recommended for use if you have an acute illness
with a high fever that requires management or are allergic to rabies vaccine or
beta propiolactone or any of the other ingredients of this medicine. Consult
your doctor before receiving BERAB 2.5IU INJECTION.

Q: How frequent should I receive BERAB 2.5IU INJECTION?

A: The pre-exposure immunisation course consists of 3 injections at Day 0, Day 7
and either Day 21 or Day 28. If you are at high risk of exposure to rabies, your
doctor will assess the need and plan further booster injections in line with
official guidance. Post-exposure prophylaxis should be initiated as early as
possible after suspected rabies exposure. Proper wound care must be done
immediately or as early as possible after exposure. It must be before
administration of rabies vaccine or rabies antibodies. Vaccine should be
administered on Day 0, Day 3, Day 7, Day 14 and Day 28 for Post-exposure
prophylaxis.

Useful Diagnostic Tests

• Complete Blood Count (CBC)