ATRABLOC 100 Injection 10ml (N)

Introduction About ATRABLOC 100 INJECTION

ATRABLOC 100 INJECTION contains Atracurium which belongs to the group of
medicines called Muscle relaxants. It relaxes your muscles and keeps your body
still (immobile) during a surgery. It also relaxes the airway muscles which help
in artificial breathing and in facilitating easy insertion of breathing tubes
into the airways.

Before receiving ATRABLOC 100 INJECTION inform your doctor if you have any heart
problems. You must also inform your doctor if you have a history of asthma or
allergic conditions, any nerve or muscle disorders, electrolyte imbalance or if
you are severely dehydrated.

ATRABLOC 100 INJECTION should be used in pregnant or breastfeeding women only if
it is considered necessary by the physician. However, it may be used during a
caesarean section in pregnant women under close supervision.

ATRABLOC 100 INJECTION may cause difficulty in breathing which is due to
relaxation of muscle involved in breathing. In such cases, your doctor might
provide you with additional ventilation support until the effect of ATRABLOC 100
INJECTION wears off.

Other most common side effects of receiving ATRABLOC 100 INJECTION are pain or
irritation at the site of injection, slow of fast heart rate, low or high blood
pressure and flushing of skin. Inform your doctor if any of these symptoms
worsen.

Uses Of ATRABLOC 100 INJECTION

• Used during surgeries to relax muscles
• Helps in artificial breathing by relaxing airway muscles
• Facilitates easy insertion of breathing tubes into the airways

How ATRABLOC 100 INJECTION Works

ATRABLOC 100 INJECTION is a muscle relaxant. It works by blocking the
transmission of nerve signals from the nerve fibers to the muscles. As a result,
it causes muscle relaxation and help you stay immobile during surgeries.
ATRABLOC 100 INJECTION can also relax the airway muscles which helps in easy
insertion of breathing tubes into the airways and in artificial breathing.

How to use ATRABLOC 100 INJECTION

ATRABLOC 100 INJECTION will be given to you only by a doctor or a nurse into the
vein (intravenously) under close monitoring. Your doctor will decide the correct
dose for you depending upon your age, body weight and health condition.

Side Effects Of ATRABLOC 100 INJECTION

Common

• slow or very fast heartbeat
• changes in blood pressure (low or high)
• difficulty in breathing
• flushing
• pain, itching or irritation at the site of injection
• redness or itchy rashes of the skin

Rare

• bronchospasm (tightness of airway muscles)

Contact your doctor immediately if you experience any of the following side
effects after receiving ATRABLOC 100 INJECTION:

• severe allergic reactions (such as skin rash, severe itching of the skin with raised lumps, blisters in the skin, swelling of the face, lips, tongue and/or throat with difficulty in breathing or swallowing)
• fits, cardiac arrest

How To Manage Side Effects

!### Injection Site Reactions

Place an ice pack on the injected site. Do not move the affected area
frequently. If the symptom worsens, consult your doctor.

Warning & Precautions

!### Pregnancy

Monitoring requiredATRABLOC 100 INJECTION should be used in pregnant women only if it is considered
necessary by the physician. Therefore, inform your doctor if you are pregnant or
think you may be pregnant before receiving ATRABLOC 100 INJECTION. However,
ATRABLOC 100 INJECTION can be used during a caesarean section in pregnant women
under close medical supervision.

!### Breastfeeding

Monitoring requiredATRABLOC 100 INJECTION should be used in breastfeeding women only if it is
considered necessary by the physician. Therefore, inform your doctor before
receiving it. The nursing infant should be monitored closely when the mother
receives this medicine.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines until the effects of this medicine wears
off completely.

!### Allergy

ContraindicatedTalk to your doctor before receiving ATRABLOC 100 INJECTION if you are allergic
to Atracurium or to any other muscle relaxants (such as pancuronium).

!### Lungs

Use with CautionATRABLOC 100 INJECTION should be used with caution in patients with a history of
asthma. Therefore, inform your doctor before receiving it.

!### Heart Disease

Use with CautionATRABLOC 100 INJECTION should be used with caution in patients with heart
problems. Therefore, inform your doctor before receiving it.

!### Use In Pediatrics

Consult your doctorATRABLOC 100 INJECTION should be used in infants, children, and in adolescents
(aged above 1 month until 18 years) under close medical supervision. It is not
suitable for use in newborns aged below 1 month of age.

!### Use In Geriatrics

Use with CautionATRABLOC 100 INJECTION should be used with caution in elderly patients.
Therefore, consult your doctor for advice before receiving it.

Others

Before receiving ATRABLOC 100 INJECTION, inform your physician if you:

• have problems in blood circulation
• have a history of allergic reactions
• have nerve or muscle disorder (such as myasthenia gravis, poliomyelitis, Eaton-Lambert syndrome etc.)
• have severe electrolyte disorders (abnormal levels of sodium, potassium and chloride in blood)
• are suffering from burns

Interactions

A. Drug-Drug interactions:

Before receiving ATRABLOC 100 INJECTION, inform your doctor if you are taking
any of the following medicines:

• lithium (a medicine used to manage bipolar disorder)
• quinine (a medicine used to manage malaria)
• neomycin, streptomycin, kanamycin, gentamicin, lincosamide and polype
• medicines used to manage irregular heartbeat (such as quinidine, amiodarone, propafenone, lidocaine, procainamide, digoxin)
• phenytoin, carbamazepine and thiopental (used to manage fits and seizures)
• diuretics (used to improve urine output) Ex. furosemide, chlorothiazide, acetazolamide
• medicines used to manage heart problems (such as propranolol, diltiazem, nifedipine, nicardipine, oxprenolol, trimetaphan, hexamethonium and verapamil)
• medicines used to manage rheumatism (such as chloroquine, d-penicillamine)
• corticosteroids (used to manage pain and inflammation) such as prednisolone, methylprednisolone
• anesthetics (medicines that causes loss of consciousness) such as isoflurane, desflurane, sevoflurane and enflurane, halothane, ketamine
• dantrolene (a muscle relaxant)
• magnesium sulphate (used to manage abnormally high blood pressure in pregnant women)
• chlorpromazine (a medicine used to manage psychiatric disorders)

Overdosage:

ATRABLOC 100 INJECTION will be administered to you only by a doctor or a nurse
in a hospital, and so it is unlikely to receive an overdose. However, consult
your doctor or nurse if you experience any unusual symptoms.

Synopsis

Drug	:	Atracurium
Pharmacological Category	:	Neuromuscular Blocking Agents
Therapeutic Indication	:	Muscle relaxant
Dosage Forms	:	Injection

More Information

• Keep ATRABLOC 100 INJECTION out of reach of children.
• Store ATRABLOC 100 INJECTION in a refrigerator between 2-8°C

FAQs About ATRABLOC 100 INJECTION

Q: What is the use of ATRABLOC 100 INJECTION?

A: ATRABLOC 100 INJECTION is a muscle relaxant used to relax your muscles and
keeps your body still (immobile) during a surgery. It also helps with artificial
breathing among patients in intensive care unit (ICU) by relaxing the airway
muscles and facilitates easy insertion of breathing tubes into the airways when
artificial breathing is necessary.

Q: What ATRABLOC 100 INJECTION does to my body?

A: ATRABLOC 100 INJECTION is a muscle relaxant. It works by blocking the
transmission of nerve signals from the nerve fibers to the muscles. As a result,
it causes muscle relaxation and help you stay immobile during surgeries.
ATRABLOC 100 INJECTION can also relax the airway muscles which helps in easy
insertion of breathing tubes into the airways and in artificial breathing.

Q: How long does the effects of ATRABLOC 100 INJECTION lasts long?

A: The effects of ATRABLOC 100 INJECTION may last between 20-40 minutes
depending upon the dosage administered.

Q: What type of drug is ATRABLOC 100 INJECTION?

A: ATRABLOC 100 INJECTION is a muscle relaxant. It belongs to neuromuscular
blocking agents, where it blocks the transmission of nerve signals from the
nerve fibers to the muscles.

Q: Why is ATRABLOC 100 INJECTION used before surgeries?

A: ATRABLOC 100 INJECTION is used prior to surgeries to relax your muscles and
to make you stay immobile by reducing involuntary muscle movements.

Q: Why is ATRABLOC 100 INJECTION used along with anesthesia?

A: ATRABLOC 100 INJECTION is used along with anesthesia prior to the surgeries
to relax your muscles and to make you immobile. It also helps with artificial
breathing among patients in intensive care unit (ICU) by relaxing the airway
muscles and facilitates easy insertion of breathing tubes into the airways when
artificial breathing is necessary.

Q: What are the side effects of ATRABLOC 100 INJECTION?

A: The most common side effects of receiving ATRABLOC 100 INJECTION are pain and
irritation at the site of injection, slow or fast heart rate, low or high blood
pressure and difficulty in breathing. Inform your doctor if any of these
symptoms worsen.

Q: Can ATRABLOC 100 INJECTION be reversed?

A: Yes. The effect of ATRABLOC 100 INJECTION reverses on its own and 25% of
recovery is expected to occur in 25 to 45 min and 95% of recovery is expected to
occur in 45 to 65 min.

Q: Is ATRABLOC 100 INJECTION an anesthetic drug?

A: ATRABLOC 100 INJECTION is a muscle relaxant, used as an adjuvant with
anesthetic medicine before undergoing a surgical procedure. It is not an
anesthetic.

Q: Will I be staying awake after using ATRABLOC 100 INJECTION?

A: ATRABLOC 100 INJECTION only relaxes your skeletal muscles and does not affect
your consciousness. However, it might make you feel dizzy or faint. However,
when ATRABLOC 100 INJECTION is used along with an anesthetic medication to
create numbness before surgery, you may become unconscious for a while. The
anesthesia used along with ATRABLOC 100 INJECTION is the reason for
unconsciousness.

Q: Is ATRABLOC 100 INJECTION safe for use in pregnant women?

A: ATRABLOC 100 INJECTION should be used in pregnant women only if it is
considered necessary by the physician. Therefore, inform your doctor if you are
pregnant or planning to become pregnant before receiving ATRABLOC 100 INJECTION.
Your doctor will decide the risks and benefits before administrating ATRABLOC
100 INJECTION to you. However, ATRABLOC 100 INJECTION can be used during a
caesarean section in pregnant women under close supervision.