XEMASIN 25mg Tablet 10's

Introduction About XEMASIN 25MG TABLET

XEMASIN 25MG TABLET contains Exemestane which belongs to the group of medicines
called Aromatase inhibitors. It is used for advanced breast cancer in
post-menopausal women whose disease has progressed following Tamoxifen therapy.
It is also used for hormone-dependent advanced breast cancer in postmenopausal
women when management with different hormonal drug management has not worked
well enough.

Breast cancer is a disease in which cells in the breast grow out of control.
There are different kinds of breast cancer. The kind of breast cancer depends on
which cells in the breast turn into cancer. Breast cancer can begin in different
parts of the breast.

Before taking XEMASIN 25MG TABLET, inform your doctor if you have liver or
kidney problem, a history or are suffering from any condition which affects the
strength of your bones. XEMASIN 25MG TABLET is not recommended for use among
pregnant and breastfeeding women. Consult your doctor before taking it. The most
common side effects of taking XEMASIN 25MG TABLET are depression, headache,
muscle, and joint pain, hair loss, and abdominal pain. Consult your doctor if
any of the side effects worsen or persists for a longer duration.

Uses Of XEMASIN 25MG TABLET

It is used for:

• advanced breast cancer in post-menopausal women whose disease has progressed following Tamoxifen therapy
• hormone-dependent advanced breast cancer in postmenopausal women when management with different hormonal drug management has not worked well enough

How XEMASIN 25MG TABLET Works

XEMASIN 25MG TABLET belongs to aromatase inhibitor which blocks the enzyme
aromatase (found in the body's muscle, skin, breast and fat), which is used to
convert androgens (hormones produced by the adrenal glands) into estrogen. In
the absence of estrogen, tumors dependent on this hormone for growth will
shrink. It works by reducing the amount of oestrogen made in the body.

How to use XEMASIN 25MG TABLET

Take XEMASIN 25MG TABLET as advised by your physician. Swallow the medicine with
a glass of water. Do not crush or chew the medicine. Your doctor will decide the
correct duration for you depending upon your age, body weight, and disease
condition.

Side Effects Of XEMASIN 25MG TABLET

Common

• skin rash, hives, itchiness, swollen hands, and feet
• hot flushes, difficulty sleeping and increased sweating (menopausal symptoms)
• reduction in the number of white blood cells, platelets, liver enzymes, blood enzymes, and hemoglobin
• carpal tunnel syndrome (combination of pins and needles, pain and numbness affecting all the hand except the little finger) or tingling/prickling of the skin
• depression
• headache
• musculoskeletal pain (bone, muscle, or joint pain)
• dizziness
• tiredness
• abdominal pain
• loss of appetite
• vomiting
• constipation
• indigestion
• diarrhea
• hair loss
• thinning of bones which might decrease their strength (osteoporosis), leading to bone fractures (breaks or cracks)
• weakness

Rare

• breaking out of small blisters
• drowsiness

Stop taking XEMASIN 25MG TABLET and contact your doctor immediately if you
experience any of the following side effects;

• hypersensitivity
• inflammation of the liver (hepatitis) and bile ducts which cause yellowing of the skin (cholestatic hepatitis)
• feeling unwell, nausea, jaundice (yellowing of the skin and eyes), itching, right-sided abdominal pain, and loss of appetite

How To Manage Side Effects

!### Diarrhea

Drink a lot of fluids such as water or fruit juice to keep yourself hydrated. Do
not consume any medicine on your own without consulting your doctor.

!### Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Avoid
eating oil-rich or spicy foods.

Warning & Precautions

!### Pregnancy

ContraindicatedXEMASIN 25MG TABLET is not recommended for use in pregnant women. Consult your
doctor before taking it.

!### Breastfeeding

ContraindicatedXEMASIN 25MG TABLET is not recommended for use in breastfeeding women. Consult
your doctor before taking it.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you feel drowsy, dizzy or weak after
taking XEMASIN 25MG TABLET.

!### Kidney

Use with CautionXEMASIN 25MG TABLET should be used with caution in patients with kidney disease.
Consult your doctor before taking it.

!### Liver

Use with CautionXEMASIN 25MG TABLET should be used with caution in patients with liver problems.
Consult your doctor before taking it.

!### Allergy

ContraindicatedDo not take XEMASIN 25MG TABLET if you are allergic to Exemestane or any of the
other ingredients of this medicine.

!### Use In Pediatrics

ContraindicatedXEMASIN 25MG TABLET is not recommended for use in children. Consult your doctor
before taking it.

!### Use In Geriatrics

Use with CautionXEMASIN 25MG TABLET should be used with caution in elderly patients. Consult
your doctor before taking it.

Others

XEMASIN 25MG TABLET is not recommended if you have:

• not already been through the menopause (still having a monthly period)

Before taking XEMASIN 25MG TABLET, inform your doctor if you:

• have a history or are suffering from any condition which affects the strength of the bones

Interactions

A. Drug-Drug interactions:

Before taking XEMASIN 25MG TABLET, inform your doctor if you are taking any of
the following medicine:

• Rifampicin (used to manage infection)
• Carbamazepine or phenytoin (used for epilepsy)
• St. John wort (Hypericum perforatum)

Overdosage:

If you or anyone else accidentally takes too much of XEMASIN 25MG TABLET,
consult your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Exemestane
Pharmacological Category	:	Aromatase inhibitors
Therapeutic Indication	:	Hormone dependent early and advanced breast cancer in postmenopausal women
Dosage Forms	:	Tablet

More Information

• Keep XEMASIN 25MG TABLET out of reach of children
• Store at room temperature

FAQs About XEMASIN 25MG TABLET

Q: How to take XEMASIN 25MG TABLET?A: Take XEMASIN 25MG TABLET as advised by your physician. Swallow the
medicine with a glass of water. Do not crush or chew the medicine. Your doctor
will decide the correct dose and duration for you depending upon your age, body
weight, and disease condition.

Q: Is it safe to use XEMASIN 25MG TABLET in older people?A: XEMASIN 25MG TABLET should be used with caution in elderly patients (aged
65 years and above). Consult your doctor before taking it.

Q: Is there any food restriction while taking XEMASIN 25MG TABLET?A: XEMASIN 25MG TABLET to be taken after meals, there is no food restriction
as such. Consult your doctor before taking it.

Q: Who should consult the doctor before taking XEMASIN 25MG TABLET?A: Patients having liver and kidney problems or having a history or
suffering from any condition which affects the strength of the bones, consult
your doctor before taking XEMASIN 25MG TABLET.

Q: Can I take XEMASIN 25MG TABLET along with Anti-epile
along with XEMASIN 25MG TABLET.