Triquilar Tablet 21'S

Introduction About TRIQUILAR TABLET

TRIQUILAR TABLET is a combination of Levonorgestrel and Ethinylestradiol which
belongs to the group of medicines called Hormonal Contrace
used as a contrace

Before taking TRIQUILAR TABLET inform your doctor if you have any lung, liver,
kidney or heart problems. You must also inform your doctor if you have asthma,
diabetes, high blood pressure, high blood cholesterol levels, migraine, obesity,
epilepsy or depression as a precaution.

TRIQUILAR TABLET is strictly not recommended for use in patients with breast
cancer, cervical cancer or liver cancer. It is also not suitable for use in
patients with depression, blood clots, stroke or any problems in blood
circulation.

TRIQUILAR TABLET is not intended for use in pregnant women, in children who have
not attained puberty and elderly women who have reached menopause. It is also
not recommended for use in breastfeeding women and in women (aged above 35
years) who have the habit of smoking.

The most common side effects of taking TRIQUILAR TABLET are vaginal infections
or inflammation, vaginal discharge, unusual spotting or bleeding, breast
tenderness, milk discharge from breasts, mood changes, low sex drive, and
changes in body weight. Consult your doctor if any of these side effects
worsens.

Uses Of TRIQUILAR TABLET

• Used as a contrace

How TRIQUILAR TABLET Works

TRIQUILAR TABLET is a contrace
suppressing ovulation (release of a mature egg from an ovary). It can also
reduce the thickness of the inner lining of the uterus which makes it not
suitable for the foetus to implant and grow.

Additionally, it can alter the thickness of the cervical mucus which makes it
difficult for the sperm to enter the uterus and fertilize the egg. As a result,
they create an unfavourable environment for a successful pregnancy.

How to use TRIQUILAR TABLET

Take TRIQUILAR TABLET strictly as advised by your physician. Swallow TRIQUILAR
TABLET with a glass of water. Do not crush or chew the medicine. TRIQUILAR
TABLET can be taken with or without meals.

Do not miss any dose of TRIQUILAR TABLET in between the therapy, as it may
reduce its effectiveness. In case you have missed a dose of TRIQUILAR TABLET,
take it as soon as you remember. Avoid taking a double dose of this medicine to
compensate for the missed dose.

Your doctor will decide the correct dose and duration of therapy for you
depending on your age, body weight and health condition.

Side Effects Of TRIQUILAR TABLET

Common

• vaginal infection, itching or inflammation
• discharge from vagina
• changes in body weight
• changes in mood (mood swings)
• depression
• changes in sex drive
• headache, tiredness
• feeling nervous
• nausea, vomiting, stomach pain
• unusual spotting or bleeding
• breast pain or tenderness
• milk discharge from breasts
• heavy periods or lack of periods
• swelling of body parts (edema)

Uncommon

• changes in blood cholesterol levels
• changes in appetite
• increase in blood pressure
• flatulence (bloating)
• skin rashes, dark patches on the skin
• hirsutism (abnormal hair growth in the body)
• hair loss

Rare

• decrease in serum folate levels
• unable to wear contact lenses
• cholestatic jaundice

Stop taking TRIQUILAR TABLET and contact your doctor immediately if you
experience any of the following side effects:

• signs of allergic reactions (such as swelling of the face, lips, mouth, tongue, or throat causing difficulty in breathing or swallowing)
• signs of breast cancer (presence of lumps in the breast, skin dimpling in the breast and changes in the nipple)
• signs of cervical cancer (smelly or bloody discharge from the vagina, unusual vaginal bleeding, pelvic pain, and painful sex)
• signs of severe liver problems (such as severe pain in your upper abdomen, yellow skin, or eyes, itching in the whole body)
• signs of a blood clot in the legs (such as swelling of the affected leg or foot accomp
• signs of a blood clot in the lungs (such as sudden unexplained breathing difficulty, rapid heart rate, sharp chest pain, severe lightheadedness, or dizziness)
• signs of a blood clot in the eyes (such as sudden loss of vision or painless blurring of vision)
• signs of heart attack (chest pain, pressure, heaviness in the chest, abnormal heartbeat, extreme weakness, anxiety, or shortness of breath, sweating, nausea, vomiting or dizziness)
• signs of stroke (sudden weakness or numbness of the face, arm, or legs, especially on one side of the body, confusion, trouble in speaking or understanding, walking, dizziness, loss of balance, fainting with or without seizure)
• swelling and slight blue discolouration of an extremity, severe stomach pain
• feeling depressed with thoughts of killing or harming yourself

How To Manage Side Effects

Headache:

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate your
headache. Consult your doctor if your headache worsens.

Nausea and Vomiting

Take TRIQUILAR TABLET with or just after meals. Stick to simple meals. Avoid
eating oil rich or spicy foods. Consult your doctor if your nausea worsens.

Warning & Precautions

!### Pregnancy

TRIQUILAR TABLET is not recommended for use in pregnant women and in women who
think that they might be pregnant. It is also not recommended for use in women
who have or ever had jaundice due to pregnancy. It should be used with
caution in pregnant women with a previous history of herpes gestationis (an
autoimmune skin disease). Therefore, consult your doctor before taking it.

!### Breastfeeding

TRIQUILAR TABLET is not recommended for use in breast-feeding women. Therefore,
consult your doctor before taking it.

!### Driving and Using Machines

TRIQUILAR TABLET has negligible effects on driving or handling heavy tools or
machines. However, do not drive or handle any heavy machines if your ability is
affected by TRIQUILAR TABLET.

!### Alcohol

Avoid consum

!### Kidney

TRIQUILAR TABLET is not recommended for use in patients with kidney diseases
(such as kidney failure). It should be used with caution in patients with other
kidney problems. Therefore, consult your doctor before taking it.

!### Liver

TRIQUILAR TABLET is not recommended for use in patients who have or ever had
liver diseases (such as liver tumours). It should be used with caution in
patients with other liver or gallbladder problems (such as jaundice, and
gallstones).Therefore, consult your doctor before taking it.

!### Allergy

Do not take TRIQUILAR TABLET if you are allergic toLevonorgestrel or
Ethinylestradiol.

!### Lungs

TRIQUILAR TABLET is not recommended for use in patients who have blood clots in
the lungs (pulmonary embolism). It should be used with caution in patients with
asthma. Therefore, consult your doctor before taking it.

!### Heart Disease

TRIQUILAR TABLET is not recommended for use in patients who have or ever had
heart diseases (such as coronary artery disease, heart attack, angina, valvular
heart disease, or arrhythmias). It should be used with caution in patients with
other heart problems. Therefore, consult your doctor before taking it.

Others

TRIQUILAR TABLET is not recommended for use if you:

• have or had blood clots in legs (deep vein thrombosis) or eyes (retinal thrombosis)
• have any type of blood clotting disorders (such as APC resistance, protein C deficiency, protein S deficiency, antithrombin-III deficiency, antiphospholipid antibodies in blood which cause immediate blood clots)
• have any pre-planned surgery
• have severe diabetes with damage to blood vessels
• have uncontrolled high blood pressure
• have high blood cholesterol and triglyceride levels
• have or ever had migraine headaches
• have or ever had or at risk of developing breast cancer or cancers in genital organs
• have hyperhomocysteinaemia (an increase in the levels of an amino acid called homocysteine in blood)
• have unexplained bleeding from the vagina
• have pancreatitis (severe inflammation of the pancreas)
• have hepatitis C infection (a type of viral infection affecting the liver)
• have adrenal insufficiency (when the body does not produce enough aldosterone hormone)
• are aged above 35 years and have a habit of smoking
• have stroke or problems in blood circulation
• have reached menopause

Before taking TRIQUILAR TABLET inform your doctor if you:

• have family history of breast cancer
• have hypertension
• have depression
• have diarrhoea/vomiting
• have otosclerosis (abnormal bone growth in the ears)
• have Crohn’s disease or ulcerative colitis (chronic inflammatory bowel disease)
• have systemic lupus erythematosus (disease affecting your immune system)
• have haemolytic uraemic syndrome (blood clotting disorder causing kidney failure)
• have sickle cell anaemia (an inherited red blood cell disease)
• have just given birth
• had an abortion in the second trimester
• have been bed-ridden or immobile for a prolonged period
• have an inflammation in the veins under the skin (superficial thrombophlebitis)
• have varicose veins (enlarged or twisted veins)
• have epilepsy
• are obese
• have porphyria (a rare inherited blood disorder)
• have abnormal body movements (chorea)
• have multiple sclerosis (an autoimmune disease, causing nerve damage)
• have tetany (involuntary muscle contractions)
• have a history of chloasma gravidarum (dark patches on the skin) in previous pregnancies
• are due to have a lab test

Use in paediatrics:

TRIQUILAR TABLET is not recommended for use in children and in adolescent girls
aged below 18 years. It is also not intended for use in female children who have
not attained puberty. Therefore, consult your doctor before taking it.

Use in geriatrics:

TRIQUILAR TABLET is not indicated for use in elderly women. Therefore, consult
your doctor before taking it.

Interactions

A. Drug - Drug interactions:

Before taking TRIQUILAR TABLET, inform your doctor if you are taking any of the
following medicines such as:

• medicines used to manage epilepsy (Ex. primidone, phenytoin, topiramate, phenobarbital, carbamazepine, oxcarbazepine, felbamate, lamotrigine)
• medicines used to manage tuberculosis (Ex. rifampicin, rifabutin)
• dexamethasone (a medicine used to manage asthma or autoimmune diseases)
• atorvastatin (a medicine used to manage high blood cholesterol levels)
• modafinil (a medicine used to reduce sleep in narcolepsy)
• troleandomycin (a medicine used to manage bacterial infections)
• ascorbic acid (a vitamin C supplement)
• medicines used to manage HIV infection (Ex. ritonavir, nevirapine, efavirenz)
• medicines used to manage fungal infections (Ex. fluconazole, griseofulvin)
• St. John’s wort (an herbal remedy used to manage mental illness)
• medicines used to manage graft rejection during organ transplants (Ex. cyclosporin)
• theophylline (used to manage breathing problems)
• flunarizine (a medicine used to manage vertigo)
• medicines used to manage hepatitis C infections (Ex. ombitasvir, paritaprevir, ritonavir and dasabuvir)
• medicines used to relive pain (Ex. ibuprofen, aceclofenac, phenylbutazone, paracetamol)
• heparin (a medicine used to manage blood clots)

Overdosage:

If you or anyone else accidentally took more TRIQUILAR TABLET, consult your
doctor immediately or visit the nearby hospital. Symptoms of overdose might
include nausea, vomiting, breast tenderness, dizziness, stomach pain, fatigue
and withdrawal bleeding.

Synopsis

Drug	:	Levonorgestrel, Ethinylestradiol
Pharmacological Category	:	Synthetic Progestins, Estrogens
Therapeutic Indication	:	Contrace
Dosage Forms	:	Tablet

More Information

• Keep TRIQUILAR TABLET out of reach of children
• Store TRIQUILAR TABLET at room temperature

FAQs About TRIQUILAR TABLET

Is it safe to take TRIQUILAR TABLET immediately after delivery?

No. Do not take TRIQUILAR TABLET immediately after delivery. Consult your doctor
before taking it because TRIQUILAR TABLET may increase the risk of blood clots
in such patients. It is advisable to take TRIQUILAR TABLET only after 4 weeks
post-delivery. However, consult your doctor before taking it.

Can TRIQUILAR TABLET be used in children?

TRIQUILAR TABLET is not recommended for use in children and in adolescent girls
aged below 18 years. It is also not intended for use in female children who have
not attained puberty. Therefore, consult your doctor before taking it.

Can TRIQUILAR TABLET be used in post-menopausal women?

TRIQUILAR TABLET is a contrace
intended for use in postmenopausal women.

Do TRIQUILAR TABLET cause cancer?

Studies have shown that TRIQUILAR TABLET may cause breast cancer in some
individuals. This is predominant, particularly in patients who had or have a
family of breast cancer. Therefore, inform your doctor if you or anyone of your
family member has breast cancer before taking TRIQUILAR TABLET as a precaution.
Also, during therapy with TRIQUILAR TABLET, your doctor would periodically
monitor your breasts and overall health to avoid the risk of breast cancer. The
risk of breast tumours gradually decreases after stopping TRIQUILAR TABLET
therapy.

Can the use of TRIQUILAR TABLET cause unexpected bleeding?

Yes. Irregular vaginal bleeding or spotting may occur while you are taking
TRIQUILAR TABLET. Such bleeding may be temporary and usually does not indicate
any serious problems. However, consult your doctor if you experience prolonged
painful bleeding.

How and when should I take TRIQUILAR TABLET?

Take TRIQUILAR TABLET strictly as advised by your physician. Swallow TRIQUILAR
TABLET with a glass of water. TRIQUILAR TABLET can be taken with or without
meals. Do not miss any dose of TRIQUILAR TABLET in between the therapy, as it
may reduce its effectiveness.

Can TRIQUILAR TABLET cause abortion?

TRIQUILAR TABLET is a contrace
fertilization. It is not capable for causing abortion.

Can the use of TRIQUILAR TABLET cause depression?

Yes. TRIQUILAR TABLET may make you feel depressed. This is because TRIQUILAR
TABLET works by controlling the hormones which can exerts its influence on the
mood and mental health. If you feel depressed, or have thoughts of harming or
killing yourself, consult your doctor immediately.

What to do if I forgot to take TRIQUILAR TABLET?

If you have missed a dose of TRIQUILAR TABLET, take proper safety measures such
as the usage of condoms to avoid pregnancy. Do not take a double dose of
TRIQUILAR TABLET to compensate for the missed ones. Spotting or sudden bleeding
can occur in case if you miss taking TRIQUILAR TABLET.

Will the use of TRIQUILAR TABLET change the length of the menstrual cycle?

Yes. There are changes for sudden spotting or vaginal bleeding while taking
TRIQUILAR TABLET. But there has been no reported evidence for long menstrual
cycles.

Will the use of TRIQUILAR TABLET produce complete protection from pregnancy?

Yes. TRIQUILAR TABLET will provide complete protection from pregnancy when all
the doses are taken correctly and regularly. But, if you miss any dose of
TRIQUILAR TABLET, it will not be effective, and you may have higher chances of
becoming pregnant.

Is the use of condemn necessary while using TRIQUILAR TABLET?

No. It is not required to use condemn while taking TRIQUILAR TABLET. But if you
miss any dose of TRIQUILAR TABLET, you should use condoms to manage unwanted
pregnancy.

Does TRIQUILAR TABLET stops periods?

No. TRIQUILAR TABLET is a birth control pill used to manage pregnancy. It
manages ovulation and creates an unfavourable environment for a fertilized egg
to implant and grow in the uterus. It is not proven to stop periods. However, it
may delay your periods or can cause irregular or scanty periods.

Can TRIQUILAR TABLET cause hair loss?

TRIQUILAR TABLET may cause hair loss in some patients. Consult your doctor if
you experience severe hair loss.

How long can I take TRIQUILAR TABLET?

Take TRIQUILAR TABLET for the stipulated duration prescribed by your doctor. You
may be advised to take TRIQUILAR TABLET every day regularly without fail. One
course would usually last up to 24 days (approximately a month). However, your
doctor will decide the duration of therapy for you. Never miss or skip a dose of
TRIQUILAR TABLET as may reduce the contrace
in between the menstrual cycle.