Speraflox 250mg Tablet 10'S

Introduction About SPERAFLOX 250MG TABLET

SPERAFLOX 250MG TABLET contains Levofloxacin, which belongs to the group of
medicines called Antibiotics. SPERAFLOX 250MG TABLET is used to manage
infections of acute sinusitis, lungs (such as long-term breathing
problems/pneumonia), urinary tract (including kidney and bladder), prostate
gland, and skin & soft tissue (including muscles) in affected individuals.

It is also used to reduce the chances of getting anthrax (pulmonary disease) or
worsening of the disease after getting exposed to anthrax-causing bacteria.

SPERAFLOX 250MG TABLET is not recommended for use in patients allergic to
levofloxacin and/or other quinolone antibiotics (such as moxifloxacin,
ciprofloxacin, and ofloxacin). It is also not recommended for use in patients
suffering from epilepsy (seizure) and/or tendinitis (inflammation/irritation of
the tendon).

Before taking SPERAFLOX 250MG TABLET, inform your doctor if you have/had brain
damage (due to stroke/other brain injury), diabetes, myasthenia gravis
(long-term neuromuscular junction disease), aneurysm (a condition that occurs
due to bulge or enlargement of a large blood vessel), organ transplantation,
heart problems (such as very slow heart rhythm, weak heart, myocardial
infarction), kidney problems, and/or liver problems.

SPERAFLOX 250MG TABLET is not recommended for use during pregnancy or in women
planning for pregnancy. It is also not recommended for use in breastfeeding
women.

SPERAFLOX 250MG TABLET is not recommended for use in children and adolescents
(aged below 18 years). The medicine can be used with caution in elderly patients
(aged above 60 years) after consulting the doctor.

The most common side effects after taking SPERAFLOX 250MG TABLET are sleeping
problems, headache, dizziness, nausea, vomiting, and/or diarrhea. Consult your
doctor if any of these symptoms worsen.

Uses Of SPERAFLOX 250MG TABLET

• Manage infections of acute sinusitis, lungs (such as long-term breathing problems/pneumonia), urinary tract (including kidney and bladder), prostate gland, and skin & soft tissue (including muscles) in affected individuals
• Reduces the risk of getting anthrax (pulmonary disease) or worsening of the disease after getting exposed to anthrax-causing bacteria

How SPERAFLOX 250MG TABLET Works

SPERAFLOX 250MG TABLET works by inhibiting DNA gyrase (an enzyme responsible for
DNA synthesis) in bacteria, which results in the destruction of bacterial cell
structure, thus managing the occurrence of bacterial infection in affected
individuals.

How to use SPERAFLOX 250MG TABLET

Take SPERAFLOX 250MG TABLET as advised by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine. Your doctor will
decide the correct dose and duration for you depending upon your age, body
weight, and disease condition.

Side Effects Of SPERAFLOX 250MG TABLET

Common

• sleeping problems
• headache, dizziness
• nausea, vomiting, diarrhea

Uncommon

• candidiasis (a fungal infection)
• anxiety, confusion, nervousness, sleepiness, trembling, and spinning sensation
• shortness of breath
• altered taste, loss of appetite, stomach upset, indigestion, stomach ache, flatulence, constipation
• itching, skin rash, red itchy welts, hyperhidrosis (increased sweating)
• joint and muscle pain
• general weakness

Rare

• signs of low blood sugar such as shakiness, sweating, headache, hunger, and/or nausea
• depression, mental problems, agitation, abnormal dreams/nightmares
• tingling sensation in hands and feet
• hearing impairment (tinnitus), blurred vision
• fever, racing heartbeat, low blood pressure, muscle weakness
• interstitial nephritis (allergic kidney reaction associated with altered kidney function and occasional kidney failure)
• sharply demarcated, erythematous patches with/without blisters

Stop taking SPERAFLOX 250MG TABLET and consult your doctor immediately in case
you experience:

• signs of allergic reaction such as rash, swallowing/breathing problems, swelling of lips/face/throat/tongue
• fits
• signs of DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) such as widespread rash, high fever, liver enzyme elevations, white blood cell abnormalities, and/or enlarged lymph nodes
• signs of SIADH (syndrome associated with impaired water excretion and low levels of sodium) such as nausea, vomiting, cramps, and/or irritability
• bruising and bleeding due to thrombocytopenia (a condition that occurs due to a lowering of blood platelet count)
• neutropenia (low white blood cell count)
• signs of hypersensitivity reaction (exaggerated immune response) such as skin rash, red itchy welts, fever, shortness of breath
• change in psychotic reactions such as hallucinations, paranoia
• serious skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis (associated with signs such as reddish macules/circular patches with central blisters on the trunk, skin peeling, ulcers of the mouth/throat/nose/genitals/eyes preceded by fever and flu-like symptoms)
• signs of liver problems such as loss of appetite, skin and eyes becoming yellow in colour, dark-coloured urine, itching, and/or abdomen
• signs of neuropathy (nerve damage) such as burning, tingling, pain, and/or numbness
• signs of severe bowel problems such as watery diarrhea, stomach cramps, fever
• pain and inflammation in tendons/ligaments
• signs of agranulocytosis (a condition that occurs due to the lowering of white blood cells) such as fever, sore throat, and/or a general feeling of being unwell
• loss of circulation due to anaphylactic shock (severe allergic reaction)
• temporary loss of consciousness/posture (syncope)
• temporary loss of vision
• signs of prolongation of QT interval such as abnormal fast heart rhythm, cardiac arrest, alteration of the heart rhythm
• signs of aortic aneurysm (a large bulge in the aortic artery) and dissection (a tear in the inner layer of the aortic artery), such as sudden, severe pain in your abdomen, chest, or back
• rapid onset of shortness of breath (especially when you lie down flat in your bed), swelling of ankles, feet, and abdomen, and/or new onset of heart palpitations
• inflammation of pancreas
• inflammation of liver
• pain/inflammation of tendon in ankle, wrist, elbow, shoulder, and/or knee
• rhabdomyolysis (condition marked by muscle rupture and muscle destruction)
• suicidal thoughts/actions
• porphyria (a very rare metabolic disease)
• impaired eyesight or other eye disturbances

How To Manage Side Effects

!### Diarrhea

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on
your own to manage diarrhea. Consult your doctor and inform them if the symptom
gets worse.

!### Dizziness Or Drowsiness

Try to rest and get enough sleep. Try to avoid driving or operating any tools or
machines while you feel dizzy. Limit consum
dizziness. Consult and inform your doctor if the symptom worsens.

Headache

If SPERAFLOX 250MG TABLET causes headache, then take rest and drink plenty of
fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a
painkiller. Headaches should usually go away after the first week of taking
SPERAFLOX 250MG TABLET. If it lasts more than a week or is severe, inform your
doctor.

!### Nausea And Vomiting

Take SPERAFLOX 250MG TABLET with or just after a meal. Stick to simple meals.
Avoid eating oil-rich or spicy foods, sugary snacks, and drinks. Avoid drinking
too much liquid along with your meals, drink slowly in between meals. Talk with
your doctor if the condition worsens

!### Skin rash Or Itching

Try to pat or tap your skin instead of scratching it. Hold a damp towel to cool
your skin. Wear loose clothing and avoid tight clothes or clothes made from wool
or synthetic fabrics. Avoid using perfumed soaps, deodorants, or moisturizers,
and use a skin softener regularly.

Warning & Precautions

!### Pregnancy

ContraindicatedSPERAFLOX 250MG TABLET is not recommended for use during pregnancy or in women
planning for pregnancy. Consult your doctor before taking SPERAFLOX 250MG
TABLET.

!### Breastfeeding

ContraindicatedSPERAFLOX 250MG TABLET is not recommended for use in breastfeeding women.
Consult your doctor before taking SPERAFLOX 250MG TABLET.

!### Driving and Using Machines

Use with CautionDo not drive or operate machines if you feel dizzy, sleepy, spinning sensation,
and/or changes in eyesight after taking SPERAFLOX 250MG TABLET.

!### Kidney

Use with CautionSPERAFLOX 250MG TABLET should be taken with caution in patients with kidney
problems. Consult your doctor before taking SPERAFLOX 250MG TABLET.

!### Liver

Use with CautionSPERAFLOX 250MG TABLET should be taken with caution in patients with liver
problems. Consult your doctor before taking SPERAFLOX 250MG TABLET.

!### Allergy

ContraindicatedDo not take SPERAFLOX 250MG TABLET if you are allergic to levofloxacin, other
quinolone antibiotics (such as moxifloxacin, ciprofloxacin, ofloxacin), and/or
any other ingredients of this medicine.

!### Heart Disease

Use with CautionSPERAFLOX 250MG TABLET should be taken with caution in patients with heart
problems such as prolonged QT interval, very slow heart rhythm, weak heart,
myocardial infarction, heart valve regurgitation, aortic aneurysm/dissection,
endocarditis, and congenital heart valve disease. Consult your doctor before
taking SPERAFLOX 250MG TABLET.

!### Use In Pediatrics

ContraindicatedSPERAFLOX 250MG TABLET is not recommended for use in children and adolescents
(aged below 18 years). Consult your doctor before taking the medicine.

!### Use In Geriatrics

Use with CautionSPERAFLOX 250MG TABLET should be taken with caution in elderly patients (aged
above 60 years). Consult your doctor before taking the medicine.

Others

SPERAFLOX 250MG TABLET is not recommended for use if you:

• have/ever had epilepsy (seizure)
• have/ever had tendinitis (inflammation/irritation of tendon) after management with quinolone antibiotics

Before taking SPERAFLOX 250MG TABLET, inform your doctor if you:

• have had damage to your brain due to a stroke or other brain injury
• are suffering from glucose-6-phosphate dehydrogenase deficiency (a genetic disorder of red blood cells)
• have ever had mental health problems
• are diabetic
• suffer from myasthenia gravis (long-term neuromuscular junction disease)
• have a history of aneurysm (bulge or enlargement of a large blood vessel)
• suffer from connective tissue disorders such as Marfan syndrome, vascular Ehlers-Danlos syndrome, Turner syndrome, and Sjogren’s syndrome
• have a salt imbalance in the blood
• suffer from vascular disorders such as Takayasu arteritis, giant cell arteritis, Behçet´s disease, high blood pressure, or known atherosclerosis, rheumatoid arthritis
• have ever developed a severe skin rash/peeling, blistering, and/or mouth sores after taking the medicine
• have received an organ transplant

Interactions

A. Drug-Drug interactions:

Before taking SPERAFLOX 250MG TABLET, inform your doctor if you are taking any
of the following medicine:

• corticosteroids (medicines used to reduce inflammation and suppress the immune system) Ex. cortisone, hydrocortisone
• other quinolone antibiotics (medicines used to manage bacterial infections) Ex. moxifloxacin, ciprofloxacin, or ofloxacin
• vitamin K antagonists (medicines used to thin blood) Ex. warfarin
• theophylline (used for breathing problems)
• non-steroidal anti-inflammatory drugs (medicines used for pain and inflammation) Ex. aspirin, ibuprofen, fenbufen, ketoprofen, indomethacin
• ciclosporin (used to manage rejection of transplanted organs)
• antiarrhythmics (medicine used for abnormal heart rhythm) Ex. quinidine, hydroquinidine, disopyramide, sotalol, dofetilide, ibutilide, amiodarone
• tricyclic antidepressants (medicines used to manage depression) Ex. amitriptyline, imipramine
• antipsychotics (medicines used to manage bipolar disorder and schizophrenia) Ex. olanzapine, risperidone, clozapine
• erythromycin, clarithromycin, azithromycin (medicines used to manage bacterial infections)
• probenecid (a medicine used for management of gout)
• cimetidine (used for ulcers and heartburn)
• iron tablets (used for anaemia)
• zinc supplements, magnesium/aluminium-containing antacids (used for acid/heart burn)
• didanosine/sucralfate (used for stomach ulcers)

Overdosage:

If you or anyone else accidentally take too much of SPERAFLOX 250MG TABLET,
consult your doctor immediately or visit the nearby hospital. Symptoms of
overdose are seizures, confusion, dizziness, less consciousness, tremor, heart
problems (associated with signs such as uneven heartbeats, nausea), and/or
stomach burning.

Synopsis

Druge	:	Levofloxacin
Pharmacological Category	:	Antibiotics
Therapeutic Indication	:	Bacterial infections, Reduce the risk of anthrax occurrence
Dosage Forms	:	Tablet, Syrup, Oral Suspension, Oral Solution, Injection, Infusion, Eye Drops, Ear drops

More Information

Storage

• Keep SPERAFLOX 250MG TABLET out of reach of children
• Store SPERAFLOX 250MG TABLET at room temperature

FAQs About SPERAFLOX 250MG TABLET

Q: What is SPERAFLOX 250MG TABLET used for?

A: SPERAFLOX 250MG TABLET is used to manage infections of acute sinusitis, lungs
(such as long-term breathing problems/pneumonia), urinary tract (including
kidney and bladder), prostate gland, and skin and soft tissue (including
muscles) in affected individuals. It is also used to reduce the risk of getting
anthrax (pulmonary disease) or worsening of the disease after getting exposed to
anthrax-causing bacteria.

Q: What are the side effects of SPERAFLOX 250MG TABLET?

A: The most common side effects after taking SPERAFLOX 250MG TABLET are sleeping
problems, headache, dizziness, nausea, vomiting, and/or diarrhea. Consult your
doctor if any of these symptoms worsen.

Q: What happens if you take more SPERAFLOX 250MG TABLET than your required dose?

A: If you or anyone else accidentally take too much of SPERAFLOX 250MG TABLET,
consult your doctor immediately or visit the nearby hospital. Symptoms of
overdose are seizures, confusion, dizziness, less consciousness, tremor, heart
problems (associated with signs such as uneven heartbeats, nausea), and/or
stomach burning.

Q: How SPERAFLOX 250MG TABLET works?

A: SPERAFLOX 250MG TABLET works by inhibiting DNA gyrase (an enzyme responsible
for DNA synthesis) in bacteria, which results in the destruction of bacterial
cell structure, thus managing the occurrence of bacterial infection in affected
individuals.

Q: How to take SPERAFLOX 250MG TABLET?

A: Take SPERAFLOX 250MG TABLET as advised by your physician. Swallow the
medicine with a glass of water. Do not crush or chew the medicine. Your doctor
will decide the correct dose and duration for you depending upon your age, body
weight, and disease condition.

Q: Who should not take SPERAFLOX 250MG TABLET?

A: SPERAFLOX 250MG TABLET is not recommended for use if you have/ever had
epilepsy (seizure), tendinitis (inflammation/irritation of tendon) after
management with quinolone antibiotics, or if you are allergic to levofloxacin,
other quinolone antibiotics (such as moxifloxacin, ciprofloxacin, or ofloxacin).

Q: Is SPERAFLOX 250MG TABLET safe for kids?

A: SPERAFLOX 250MG TABLET is not recommended for use in children and adolescents
(aged below 18 years). Consult your doctor before taking the medicine.

Q: Can SPERAFLOX 250MG TABLET be used during pregnancy?

A: SPERAFLOX 250MG TABLET is not recommended for use during pregnancy or in
women planning for pregnancy. Consult your doctor before taking SPERAFLOX 250MG
TABLET.

Q: How long should I take SPERAFLOX 250MG TABLET?

A: Take SPERAFLOX 250MG TABLET as advised by your physician. Your doctor will
decide the correct dose and duration for you depending upon your age, body
weight, and disease condition.

Q: Is SPERAFLOX 250MG TABLET safe for kidneys?

A: SPERAFLOX 250MG TABLET should be taken with caution in patients with kidney
problems. Consult your doctor before taking SPERAFLOX 250MG TABLET.

Useful Diagnostic Tests

• Complete Blood Count (CBC)/ Hemogram
• Culture & Sensitivity, Blood
• Liver Function Test (LFT)
• Kidney Function Test (KFT)
• Serum Electrolytes/ Electrolytes Profile
• Full Body Health Checkup Advanced
• Healthy Midlife Checkup
• Full Body Checkup - Gold
• Full Body Checkup – Silver