SIZODON 1MG ORAL SUSPENSION 60ML (N)

Introduction About SIZODON 1MG ORAL SUSPENSION

SIZODON 1MG ORAL SUSPENSION contains Risperidone which belongs to a group of
medicines called Anti-psychotics. It is indicated for the management of
schizophrenia and m
short-term management of long-term aggressiveness in Alzheimer’s dementia (a
memory disorder) and in intellectually disabled children (at least 5 years of
age).

Schizophrenia is a psychiatric disorder characterized by symptoms like seeing,
hearing or feeling things that are not there, disorg
abnormal movements and negative symptoms (social isolation, lack of emotion,
etc).  M
sleep, hyperactivity, uncontrollable thought and speech, probably associated
with careless or violent behaviour.

While managing you with SIZODON 1MG ORAL SUSPENSION, your doctor might want you
to take certain diagnostic tests such as blood sugar level, prolactin levels, or
keeping a check on your body weight.

Avoid consum
taking SIZODON 1MG ORAL SUSPENSION, inform your doctor if you have liver, kidney
or heart problems, or about to have any eye surgery, diabetes, Parkinson’s
disease, epilepsy, painful or prolonged erection.

SIZODON 1MG ORAL SUSPENSION is not recommended in pregnant women and should be
used with caution in breastfeeding women. SIZODON 1MG ORAL SUSPENSION is not
recommended for use in elderly patients having dementia and should be used with
caution in other elder patients, therefore consult your doctor before taking.
SIZODON 1MG ORAL SUSPENSION is not recommended for children and adolescents
under 18 years age for schizophrenia or bipolar m

The most common side effects of taking SIZODON 1MG ORAL SUSPENSION are sleep
problems, irritability, depression, weight gain, dizziness, tremor, and
headache. Contact your doctor if any of the symptoms worsen or doesn’t improve.

Uses Of SIZODON 1MG ORAL SUSPENSION

Manages,

• schizophrenia
• m
• long-term aggression in people with Alzheimer’s dementia
• long-term aggression in intellectually disabled children

How SIZODON 1MG ORAL SUSPENSION Works

SIZODON 1MG ORAL SUSPENSION shows antipsychotic activity by blocking certain
receptors (D2 and 5-HT2) in the brain, thus decreasing symptoms of schizophrenia
and mood disorders.

How to use SIZODON 1MG ORAL SUSPENSION

Take SIZODON 1MG ORAL SUSPENSION as advised by your physician. Shake well before
use. Do not stop taking SIZODON 1MG ORAL SUSPENSION unless your doctor advice
you to stop. Your doctor will decide the correct dose of SIZODON 1MG ORAL
SUSPENSION and duration for you depending upon your age, body weight and disease
condition.

Side Effects Of SIZODON 1MG ORAL SUSPENSION

Common

• difficulty falling or staying asleep, feeling sleepy, impaired alertness
• parkinsonism (slow or impaired movement, sensation of stiffness or tightness of the muscles, sensation of freezing up and then restarting, slow shuffling walk, increased saliva or drooling, a loss of expression on the face, a tremor while at rest)
• headache
• dizziness
• tremor
• raised levels of a hormone called "prolactin" (symptoms in men include breast swelling, difficulty in getting or maintaining erections, decreased sexual desire or other sexual dysfunction. In women they may include leakage of milk from the breasts, breast discomfort, missed menstrual periods, or other problems with your cycle or fertility problems)
• pneumonia (infection of the lungs), common cold and flu symptoms, sinus infection, urinary tract infection, ear infection
• weight gain, raised appetite, weight loss, decreased appetite
• irritability, depression, anxiety (worry, uneasiness), restlessness, sleep disturbances
• dystonia (slow or sustained involuntary contraction of facial and other muscles including abnormal movements of the eyes, mouth, tongue or jaw)
• dyskinesia (involuntary muscle movements like repetitive, spasm-like movements, or twitching), tremor (shaking)
• blurred vision, infection of the eye (pink eye)
• fast heart rate, raised blood pressure, shortness of breath
• throat pain, cough, nose bleeds, stuffy nose
• stomach pain and discomfort, vomiting, nausea, constipation, diarrhoea, indigestion, dry mouth
• toothache
• rash, skin redness
• muscle spasms, or bone, muscle, back and joint pain
• incontinence (lack of control) of urine
• swelling affecting the body, arms or legs
• chest pain, weakness, fatigue (tiredness), pain
• fall

Uncommon

• infection of the eye, tonsils, nails, skin, an infection confined to a single area of skin or part of the body, viral infection, skin inflammation due to mites
• diabetes (high blood sugar), too much drinking of water
• increased blood cholesterol
• m
• unresponsive to stimuli, loss or low level of consciousness
• a restless urge to move parts of your body, balance disorder, abnormal coordination, dizziness upon standing, disturbance in attention, speech problems, loss or abnormal sense of taste, reduced sensation of skin to pain and touch, a tingling, pricking sensation or numbness of skin
• increased sensitivity of the eyes to light, dry and red eyes, increased tears
• vertigo (spinning sensation), ringing in the ears, ear pain
• palpitations (fluttering or pounding feeling in your chest)
• low blood pressure (especially while standing up), flushing
• stomach or intestinal infection, lack of voluntary control over defecation, very hard stool, difficulty swallowing, excessive passing of gas or wind
• itching, hair loss, thickening of skin, eczema (an inflammatory skin condition), dry and discolored skin, acne, flaky, itchy scalp, skin disorder, skin lesion
• abnormal posture, joint stiffness and swelling, weak muscles, neck pain
• frequent urination, inability to pass urine, pain when passing urine
• erectile dysfunction, ejaculation disorder
• loss of, or missed menstrual periods, or other problems with your cycle (females)
• development of breasts in men
• leakage of milk from the breasts, sexual dysfunction, breast pain and discomfort, vaginal discharge
• swelling of the face, eyes, lips or mouth
• chills, increase in body temperature
• change in the way you walk
• convulsions
• feeling unwell, chest discomfort
• pain related to diagnostic or management procedures

Rare

• infection
• sleep walking, sleep-related eating disorder
• inappropriate secretion of antidiuretic hormone (hormone controlling urine)
• sugar in the urine, raised blood triglycerides (type of fat)
• low blood sugar
• absence of emotion, inability to reach orgasm
• catatonia (unable to move or respond while awake)
• blood vessel problems in the brain
• coma due to uncontrolled diabetes
• shaking of the head
• glaucoma (increased pressure within the eyeball), eye rolling, problems with movement of your eyes, eyelid margin crusting
• eye problems during cataract surgery
• dangerously excessive intake of water
• chapped lips, swollen tongue, skin rash related to drug
• dandruff
• pain in muscles and breakdown of muscle fibres (rhabdomyolysis)
• irregular heartbeat
• trouble breathing during sleep, fast, shallow breathing
• inflammation of the pancreas
• raised blood insulin levels (a hormone that controls blood sugar levels)
• low body temperature, coldness in arms and legs
• symptoms of drug withdrawal
• jaundice (skin and the eyes appears yellowish)

Stop taking SIZODON 1MG ORAL SUSPENSION and consult your doctor immediately if
you experience any of the following side effects:

• have dementia and feel a sudden change in your mental state or sudden numbness or weakness involving your face, arms or legs, especially on one side, or slurred speech (even for a short period of time)
• experience tardive dyskinesia (uncontrollable twitching or jerking movements in your face, tongue, or other parts of your body)
• experience blood clots in the veins, particularly in the legs (symptoms include swelling, pain, and redness), which can travel through blood vessels to the lungs leading to chest pain and breathlessness
• experience severe allergic reaction indicated by fever, swelling of mouth, face, lip or tongue, breathlessness, itching, skin rash or low blood pressure
• glaucoma (increased pressure within the eyeball)
• rhabdomyolysis (breakdown of muscle fibres making the muscles weak and sores)
• extremely low numbers of the white blood cells needed to fight infection in your blood
• high temperature, muscle stiffness, sweating or a lowered level of consciousness (Neurole
• if you are a man and experience prolonged or painful erection (priapism)

How To Manage Side Effects

Diarrhea:

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do
not consume any medicine on your own without consulting your doctor. Ask for
your doctor’s advice if diarrhea doesn’t improve.

Nausea:

Take SIZODON 1MG ORAL SUSPENSION with or after meals. Stick to simple meals and
avoid eating rich or spicy food. Do not take any medication on your own. Ask for
your doctor’s advice if nausea doesn’t improve.

Headache:

Try to take rest and don’t involve yourself in exertive activities. Rest in a
quiet and dark room. Apply a pain-relieving balm on your forehead. Ask for your
doctor’s advice if headache doesn’t improve

Vomiting:

Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, oily, or
sweet foods. Avoid carbonated drinks. Ask for your doctor’s advice if vomiting
doesn’t improve.

Dizziness:

Lie, or sit down immediately when you feel dizzy. If you're feeling severe
episode of spinning(vertigo), lie in a dark and quite place with eyes closed.
Try to avoid vehicle driving. Discuss with your doctor if the symptom worsens.

Stomach pain:

Try to rest and relax. Try to have smaller and frequent meals. Keep a heat pad
on your stomach. Take your physic

Constipation:

Eat plenty of fiber rich foods such as vegetables, fresh fruits, and cereals and
drink plenty of water while taking SIZODON 1MG ORAL SUSPENSION. Exercise more
regularly. Ask for your doctor’s advice if constipation doesn’t improve

Muscle pain:

Give your body a rest. Do not overexert or over stretch yourself. Do stress
relieving activities such as yoga or meditation. If the symptom doesn’t improve,
ask for your doctor’s advice.

Warning & Precautions

!### Pregnancy

SIZODON 1MG ORAL SUSPENSION is not recommended for use in pregnant women unless
considered clearly necessary. If SIZODON 1MG ORAL SUSPENSION is given in the
last trimester of pregnancy it can cause agitation, hypertonia, hypotonia,
tremor, sleepiness, respiratory distress, or feeding disorder in the newborn
babies. Consult your doctor before taking SIZODON 1MG ORAL SUSPENSION.

!### Breastfeeding

SIZODON 1MG ORAL SUSPENSION should be used with caution in breast-feeding women
as it passes through breast milk. Consult your doctor before taking SIZODON 1MG
ORAL SUSPENSION.

!### Driving and Using Machines

Do not drive or use any tools and machines if you feel dizziness, tiredness, and
vision problems after taking SIZODON 1MG ORAL SUSPENSION.

!### Alcohol

Avoid consum
cause sedation.

!### Kidney

SIZODON 1MG ORAL SUSPENSION should be taken with caution in patients with severe
kidney disease. Consult your doctor before taking it.

!### Liver

SIZODON 1MG ORAL SUSPENSION should be taken with caution in patients with severe
liver disease. Consult your doctor before taking it.

!### Allergy

Do not take SIZODON 1MG ORAL SUSPENSION if youare allergic to Risperidone or any
other ingredients of this medicine.

!### Heart Disease

SIZODON 1MG ORAL SUSPENSION should be taken with caution if you have heart
problems including an irregular heart rhythm, or if you are prone to low blood
pressure. Consult your doctor before taking SIZODON 1MG ORAL SUSPENSION.

Others

Before taking SIZODON 1MG ORAL SUSPENSION, inform your doctor if you:

• know any factors that would cause stroke like high blood pressure or blood vessel issues in the brain
• have ever had involuntary movements of the tongue, mouth and face
• have ever had a condition having symptoms like high temperature, muscle stiffness, sweating or a lowered level of consciousness (also known as Neurole
• have Parkinson’s disease (shaking, stiffness, and difficulty with walking, balance, and coordination) or dementia (memory loss)
• are diabetic (having low blood sugar levels)
• have epilepsy (fits)
• are a man and you have ever experienced a prolonged or painful erection
• find it difficult controlling your body temperature or overheating
• have a tumour
• or any member of your family has a history of blood clots
• are about to have any eye operation

Use in paediatrics:

SIZODON 1MG ORAL SUSPENSION is not recommended for children under 5 years of age
for conduct disorder, and children and adolescents under 18 years age for
schizophrenia or bipolar m
SIZODON 1MG ORAL SUSPENSION to your child.

Use in geriatrics:

SIZODON 1MG ORAL SUSPENSION is not recommended in elderly who have dementia
induced by stroke and should be used with caution in other elderly patients.
Consult your doctor before taking SIZODON 1MG ORAL SUSPENSION.

Interactions

A. Drug - Drug interactions:

Before taking SIZODON 1MG ORAL SUSPENSION, inform your doctor if you are taking
any of the following medicine:

• benzodiazepines (used to calm you down) Ex. diazepam, lorazepam
• opiates (used to reduce pain) Ex. morphine, codeine
• antihistamines (used in allergies) Ex. brompheniramine, chlorpheniramine
• medicines used for heart conditions (to manage irregular heart rhythms, high blood pressure) Ex. quinidine, furosemide, chlorthiazide, verapamil
• antidepressants (used to manage depression) Ex. fluoxetine, paroxetine
• medicines that cause a slow heartbeat (Ex. Diltiazem, atenolol)
• anti-parkinsonian drugs (used to manage parkinsonism) Ex. Levodopa
• psychostimulants (used to manage attention deficit hyperactivity disorder (ADHD)) Ex. Methylphenidate
• rifampicin (used to manage infections)
• anti-epile
• phenothiazines (used to manage psychosis or to calm down) Ex. Chlorpromazine, fluphenazine
• H2 blockers (used to manage pe
• anti-fungals (used to manage fungal infections) Ex. itraconazole, ketoconazole
• anti-retrovirals (used to manage HIV/AIDS) Ex. ritonavir
• sertraline, fluvoxamine (used to manage depression and other psychiatric disorders)

B. Drug - Food interactions:

SIZODON 1MG ORAL SUSPENSION should not be mixed with coffee or tea.

Overdosage:

If you or anyone else accidentally take too much of SIZODON 1MG ORAL SUSPENSION,
consult your doctor immediately or visit the nearby hospital. Symptoms of
SIZODON 1MG ORAL SUSPENSION overdose are feeling sleepy or tired, or having
abnormal body movements, problems standing and walking, feeling dizzy due to low
blood pressure, or having abnormal heartbeats or fits.

Synopsis

Drug	:	Risperidone
Pharmacological Category	:	Atypical Antipsychotics
Therapeutic Indication	:	Schizophrenia, M
Dosage Forms	:	Tablet, Orally disintegrating tablets, Injection, Oral solution, Syrup

More Information

• Keep SIZODON 1MG ORAL SUSPENSION out of reach of children
• Do not store SIZODON 1MG ORAL SUSPENSION above 25°C

FAQs About SIZODON 1MG ORAL SUSPENSION

CanSIZODON 1MG ORAL SUSPENSIONcause seizures?

Yes. Seizures are one of the serious side effects of SIZODON 1MG ORAL
SUSPENSION. Immediately consult your doctor if you feel any symptoms such as
uncontrollable jerking movements of hands and legs, loss of consciousness, fear,
anxiety or temporary confusion after taking SIZODON 1MG ORAL SUSPENSION.

CanSIZODON 1MG ORAL SUSPENSIONbe used for sleep?

Some studies have suggested that SIZODON 1MG ORAL SUSPENSION can improve the
quality of sleep in schizophrenic patients. Consult your doctor before taking.

CanSIZODON 1MG ORAL SUSPENSIONcause weight gain?

Yes. Weight gain is one of the common side effects of SIZODON 1MG ORAL
SUSPENSION. Consult your doctor if you feel like you are gaining weight or there
is an increase in your appetite after taking SIZODON 1MG ORAL SUSPENSION.

CanSIZODON 1MG ORAL SUSPENSIONbe used for anxiety?

It has been found that low dose of SIZODON 1MG ORAL SUSPENSION as adjuvants to
SSRIs (Selective serotonin reuptake inhibitors) are useful in generalized
anxiety disorder. Consult your doctor before taking.

Can SIZODON 1MG ORAL SUSPENSION be taken with food?

Yes. SIZODON 1MG ORAL SUSPENSION can be taken with or without food. If you
experience any side effects like nausea or vomiting, it is advisable to take it
immediately after a meal. Have light meals and eat them slowly and in a frequent
manner. Avoid oily and sweet foods while on SIZODON 1MG ORAL SUSPENSION. SIZODON
1MG ORAL SUSPENSION should be diluted with water or orange juice and consumed
immediately. SIZODON 1MG ORAL SUSPENSION should not be mixed with coffee or tea.

What precautions do I need to follow while taking SIZODON 1MG ORAL
SUSPENSION?

Patients taking SIZODON 1MG ORAL SUSPENSION must inform their doctor about their
pre-existing disease conditions like kidney, heart, or liver problems. Patients
should also inform if they are pregnant, breast-feeding, or having any
allergies. Avoid alcohol consum
experience any unusual symptoms after taking SIZODON 1MG ORAL SUSPENSION.

Can SIZODON 1MG ORAL SUSPENSION be used on infants?

No. SIZODON 1MG ORAL SUSPENSION is not recommended for management of conduct
disorder in children under 5 years of age. Your doctor will decide the correct
dose or select a suitable alternative therapy for your child.

CanSIZODON 1MG ORAL SUSPENSIONcause stroke?

Yes. Its a serious side effect of SIZODON 1MG ORAL SUSPENSION that requires
immediate hospitalization. A caution about increased risk of stroke in the
elderly who are taking SIZODON 1MG ORAL SUSPENSION has been issued. Consult your
doctor if you have dementia and experience a sudden change in your mental state
or sudden weakness or numbness of your face, arms or legs, particularly on one
side, or slurred speech, even for a small period of time.

Can SIZODON 1MG ORAL SUSPENSION completely manage schizophrenia?

SIZODON 1MG ORAL SUSPENSION can help ease the symptoms of your disease and stop
your symptoms from coming back, thus helping you cope with the disease and
improve the quality of your life.

How do I takeSIZODON 1MG ORAL SUSPENSION?

SIZODON 1MG ORAL SUSPENSION comes with a syringe. It is used to help you measure
the exact amount of medicine you need. Fill the syringe with a prescribed amount
of SIZODON 1MG ORAL SUSPENSION. Empty the syringe into a glass of water or
orange juice and consume immediately. Wash the syringe with water and let it dry
before the next use.

Useful Diagnostic Tests

• Blood sugar level
• Prolactin levels
• EEG