Rheonex MF 500/250mg Tablet 6'S

Introduction About RHEONEX MF 500/250MG TABLET

RHEONEX MF 500/250MG TABLET contains a combination of Mefenamic acid and
Tranexamic acid, which belongs to the group of medicines called Non-Steroidal
Anti-inflammatory Drugs (NSAIDs) and antifibrinolytics. It helps to stop/arrest
bleeding and relieve pain and swelling from various parts of the body. It is
used to manage, control and manage heavy menstrual bleeding (menorrhagia) and
menstrual pain, bleeding from the nose or eyes, following a tooth extraction,
prostate surgery etc.

Tranexamic acid works by managing the breakdown of blood clots by blocking the
interaction of plasminogen with fibrin. Mefenamic acid works by managing the
release of a chemical messenger called prostaglandin by inhibiting an enzyme
called cyclooxygenase that causes fever, pain and inflammation in the body
(redness and swelling). Your doctor may suggest you take relevant medical tests
to understand your existing condition.

RHEONEX MF 500/250MG TABLET is not recommended for use if you have severe kidney
disease or failure, blood clots (thrombosis), abnormal body movements such as
fits or seizures, an abnormal or excessive bleeding disorder (consum
coagulopathy), etc. RHEONEX MF 500/250MG TABLET should be used with caution.
Inform your doctor if you have blood in the urine, uncontrolled bleeding, blood
clots throughout your body, irregular menstruation, mild to moderate kidney or
liver disease, angioneurotic oedema (HANO), etc.

RHEONEX MF 500/250MG TABLET should be used with caution in pregnant women and
nursing mothers and only if prescribed by a doctor. The most common side effects
of RHEONEX MF 500/250MG TABLET are feeling sick, vomiting, having a headache,
having an abnormal heartbeat, having changes in blood pressure, having
difficulty urinating, having urine leaks, etc. Contact your doctor if the
symptoms worsen.

Uses Of RHEONEX MF 500/250MG TABLET

• To manage, control and manage bleeding and pain in conditions such as heavy menstrual bleeding (Menorrhagia), Dysfunctional uterine bleeding (DUB), tooth removal, nose bleeds etc.

How RHEONEX MF 500/250MG TABLET Works

Tranexamic acid works by managing the breakdown of blood clots by blocking the
interaction of plasminogen with fibrin. Mefenamic acid works by managing the
release of a chemical messenger called prostaglandin by inhibiting an enzyme
called cyclooxygenase that causes fever, pain and inflammation in the body
(redness and swelling). As a result, RHEONEX MF 500/250MG TABLET management
controls and manages severe loss of blood and pain.

How to use RHEONEX MF 500/250MG TABLET

Take RHEONEX MF 500/250MG TABLET as advised by your physician. Swallow the
medicine with a glass of water. Do not crush or chew the medicine. Your doctor
will decide the correct dose, frequency and duration for you depending on your
age, body weight and disease condition.

Side Effects Of RHEONEX MF 500/250MG TABLET

Common

• feeling sick
• vomiting
• heartburn
• ingestion
• stomach pain or discomfort
• loose stools
• nose block
• tiredness
• muscle or joint pain
• pain or swelling of the sinus
• low red blood cells (anaemia)

Rare

Stop taking RHEONEX MF 500/250MG TABLET and contact your doctor immediately if
you experience any of the following side effects:

• severe allergic reactions (such as skin rash, severe itching of the skin with raised lumps, blisters in the skin, swelling of the face, lips, tongue and/or throat with difficulty in breathing or swallowing).
• chest pain or heaviness in the chest
• difficulty in breathing
• coughing up blood
• fainting
• pain or swelling of the legs or arms
• impaired or blurring of vision
• bleeding in the eyes

How To Manage Side Effects

Nausea (feeling sick) or vomiting:

Take RHEONEX MF 500/250MG TABLET with or just after meals. Stick to simple
meals. Avoid eating rich or spicy food.

Headache:

Take rest and get adequate sleep and stay hydrated. Consult your doctor
immediately if the symptoms persist or worsen.

Diarrhea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated.
Consult your doctor immediately if the symptom did not improve.

Warning & Precautions

!### Pregnancy

RHEONEX MF 500/250MG TABLET should be used with caution in pregnant women, only
if recommended by your doctor. Consult your doctor before taking it.

!### Breastfeeding

RHEONEX MF 500/250MG TABLET should be used with caution in breastfeeding
mothers, only if recommended by your doctor. Consult your doctor before taking
it.

!### Driving and Using Machines

Do not drive or operate any heavy tools or machines. If you are experiencing
improper vision, dizziness etc.

!### Alcohol

Avoid consuming alcohol while using RHEONEX MF 500/250MG TABLET, as it may
worsen your existing condition and increases the risk of bleeding in the
stomach. Consult your doctor before taking it.

!### Kidney

RHEONEX MF 500/250MG TABLET is not recommended for use if are having severe
kidney disease such as kidney failure etc. Consult your doctor before taking it.

!### Liver

RHEONEX MF 500/250MG TABLET should be used with caution if you are having liver
disease. Consult your doctor before taking it.

!### Allergy

Do not take RHEONEX MF 500/250MG TABLET if you are allergic to Tranexamic acid
and Mefenamic acid.

Others

RHEONEX MF 500/250MG TABLET is not recommended for use if you have:

• thrombosis – blood clot or blockage in blood vessels
• fits or seizure
• excessive bleeding disorder such as consum

Before taking RHEONEX MF 500/250MG TABLET, inform your physician if you have:

• blood in the urine
• uncontrolled bleeding
• irregular menstrual period
• angioneurotic oedema (HANO)

Use in Pediatrics:

The safety of the usage of RHEONEX MF 500/250MG TABLET in children is not known.
Consult your doctor for advice.

Use in Geriatrics:

RHEONEX MF 500/250MG TABLET should be used with caution in an elderly patient.
Consult your doctor before taking this medicine.

Interactions

A. Drug-Drug interactions:

Before taking RHEONEX MF 500/250MG TABLET, inform your doctor if you are taking
any of the following medicine.

• birth control medications such as desogestrel, estradiol, dienogest, drospirenone etc.
• streptokinase – used to break down blood clots.
• Ibuprofen, paracetamol, celecoxib – used to manage pain, fever and swelling

B. Drug - Food interaction:

The possible interaction of RHEONEX MF 500/250MG TABLET with foods is not known.
Consult your doctor for advice.

Overdosage:

If you or anyone else accidentally take too much of RHEONEX MF 500/250MG TABLET,
consult your doctor immediately or visit the nearby hospital. Symptoms of
overdose are feeling sick, vomiting, dizziness or lightheadedness, fits or
seizure etc

Synopsis

Drug	:	Mefenamic acid, Tranexamic acid
Pharmacological Category	:	Non-steroidal Anti-inflammatory Drugs (NSAIDs), Anti-fibrinolytics
Therapeutic Indication	:	To manage, manage and control bleeding and relieve pain
Dosage Forms	:	Tablet, Capsule, Injection

More Information

• Keep out of reach of children
• Keep away from sunlight
• Store at room temperature

FAQs About RHEONEX MF 500/250MG TABLET

Q: Can RHEONEX MF 500/250MG TABLET be used for managing heavy menstrual
bleeding?

A: Heavy menstrual bleeding is caused by several conditions, such as a fibroid
in the uterus, the unusual shape of the womb, the irregular or abnormal lining
of the uterus, a clotting disorder, etc. They present with bleeding and pain.
RHEONEX MF 500/250MG TABLET helps to stop bleeding and relieve pain.

Q: Who is not recommended for using RHEONEX MF 500/250MG TABLET?

A: RHEONEX MF 500/250MG TABLET is not recommended for use in patients with
active diseases such as severe kidney disease, fits or seizures, excessive
bleeding, blood clots in blood vessels (thrombosis), etc.

Q: What to do if RHEONEX MF 500/250MG TABLET is taken in excess

A: If you or anyone else accidentally takes too much RHEONEX MF 500/250MG
TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms
of overdose are feeling sick, vomiting, dizziness or light-headedness, stomach
pain, etc.

Q: Is RHEONEX MF 500/250MG TABLET safe to use in a kidney disease patient?

A: RHEONEX MF 500/250MG TABLET should be used with caution if you have mild to
moderate kidney disease. It is not recommended for use if you have severe kidney
disease, such as kidney failure. Consult your doctor for advice.

Q: Is it safe to use RHEONEX MF 500/250MG TABLET while taking birth control
oral contrace

A: The use of birth control medicine such as desogestrel, estradiol, dienogest,
drospirenone, etc. may interact when used with RHEONEX MF 500/250MG TABLET,
whichresults in worsening side effects.

Useful Diagnostic Tests

• CBC
• Fasting Blood Sugar Test
• Glucose Tolerance Test
• Random Blood Sugar Test
• HBA1c
• KFT - Kidney function test
• LFT – Liver function test
• RFT – Renal function test
• ECG
• Cardiac ECHO
• Ultrasound
• Hysteroscopy test
• Biopsy
• Bleeding time and clotting time
• D-Dimer test
• ESR
• CRP