PURELITE 250mg Tablet 10's

Introduction About PURELITE 250MG TABLET

PURELITE 250MG TABLET contains Tranexamic Acid which belongs to the group of
medicines called Antifibrinolytics. It is used in the management of bleeding in
conditions such as heavy menstrual bleeding in women, bleeding inside the
digestive system (Ex. inflammatory bowel disease), bleeding from the nose, blood
in urine (not caused by the kidney (renal parenchyma)), control bleeding after
dental extraction in patients with coagulopathies and after cervix surgery.

PURELITE 250MG TABLET is not recommended for use in patients with blood clotting
disorder or consum
irregular menstrual cycle, acquired disturbances of color vision, venous or
arterial thrombosis, active thromboembolic diseases such as deep vein
thrombosis, pulmonary embolism and cerebral thrombosis, subarachnoid hemorrhage
and blood in urine during periods.

Before taking PURELITE 250MG TABLET, inform your doctor if you had or have
changes in normal bleeding pattern, family history of endometrial cancer,
abnormal bleeding between periods, bleeding during or after sexual intercourse,
premenstrual pain, lower abdominal pain, bleeding after menopause, are at risk
of having a blood clot, diabetic, overweight, polycystic ovary syndrome (PCOS).

PURELITE 250MG TABLET should be used with caution in pregnant and breast-feeding
women only if clearly advised by the doctor. Consult your doctor before taking
PURELITE 250MG TABLET. Your doctor may recommend you to take relevant tests to
understand your existing condition.

Safety and effectiveness of PURELITE 250MG TABLET in children and adolescents
below 18 years of age has not been established yet and it is not recommended for
use in elderly women after menopause (stoppage of periods).

The most common side effects of taking PURELITE 250MG TABLET are nausea,
vomiting, diarrhea, headache, tiredness and stomach pain. Consult your doctor
immediately if any of the side effect worsens.

Uses Of PURELITE 250MG TABLET

It is used to manage bleeding in conditions such as:

• heavy menstrual bleeding in women
• bleeding from the nose
• bleeding inside the digestive system (gastrointestinal system, Ex. inflammatory bowel disease))
• blood in urine (not caused by the kidney (renal parenchyma))
• bleeding after undergoing surgery (such as dental extraction in patients with coagulopathies, cervix surgery)

How PURELITE 250MG TABLET Works

PURELITE 250MG TABLET manages bleeding by blocking the plasminogen from binding
with fibrin which results in bleeding. As a result, it manages and controls
bleeding associated with various conditions.

How to use PURELITE 250MG TABLET

Take PURELITE 250MG TABLET as directed by your physician. Swallow the medicine
as a whole and do not crush or chew the medicine. Do not take this medicine
before your period has started as it will not work properly. Your doctor will
decide the correct dose, duration and frequency of PURELITE 250MG TABLET for you
depending upon age, weight and disease conditions.

Side Effects Of PURELITE 250MG TABLET

Common

• nausea, vomiting
• diarrhea, stomach pain
• headache
• sinus and nasal symptoms
• back, muscle or joint pain
• muscle cramps
• migraine
• anemia
• tiredness

Uncommon

• allergic skin reactions

Rare

• thromboembolic events (blood clot in vein)
• vision disturbances
• giddiness

Stop taking PURELITE 250MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• impaired vision (especially color), blood clot in the eye
• itchy, red or swollen skin
• serious blood clots
• pain or feelings of heaviness in the chest
• pain or swelling in the arms or legs
• sudden shortness of breath, fainting
• coughing up blood

How To Manage Side Effects

Nausea or vomiting:

Stick to simple meals while taking this medicine. Avoid eating oily rich, fried
or spicy foods. Do not lie down or sleep immediately after eating. Consult your
doctor if the symptom does not improve.

Diarrhoea:

Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating
high-fat or spicy foods. Try to avoid taking any medicine on your own to manage
diarrhea and consult your doctor if the symptom gets worse.

Headache:

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to
be relaxed and stress free. Apply pain relieving balm on your forehead if
necessary. Consult your doctor if the symptom does not improve.

Stomach pain:

Try to rest and relax. Eat and drink slowly or try to have smaller meals more
frequently. Keep a heat pad on your stomach. If the symptom does not improve,
consult your doctor.

Warning & Precautions

!### Pregnancy

PURELITE 250MG TABLET should be used with caution in pregnant women only if
considered clearly necessary. Inform your doctor immediately if you become
pregnant or think you may be pregnant before using PURELITE 250MG TABLET.

!### Breastfeeding

PURELITE 250MG TABLET should be used with caution in breastfeeding women only if
advised by the doctor as it may pass through the breast milk. Consult your
doctor before taking PURELITE 250MG TABLET.

!### Driving and Using Machines

Do not drive or operate any machines if you experience dizziness after taking
PURELITE 250MG TABLET.

!### Kidney

PURELITE 250MG TABLET is not recommended for use in patients with severe kidney
impairment.  PURELITE 250MG TABLET should be used with caution in patients with
mild to moderate kidney impairment and your doctor may adjust the dose depending
upon kidney function. Consult your doctor for advice before taking PURELITE
250MG TABLET.

!### Liver

No dose adjustment is required in patients with hepatic impairment. Consult your
doctor for advice.

!### Allergy

Do not take PURELITE 250MG TABLET if you are allergic to Tranexamic Acid or any
other ingredients of this medicine.

!### Lungs

PURELITE 250MG TABLET is not recommended for use in patients with pulmonary
embolism (arteries of the lungs are blocked by clot). Consult your doctor before
taking PURELITE 250MG TABLET.

Others

PURELITE 250MG TABLET is not recommended for use if you:

• have a blood clotting disorder (consum
• have history of fits or seizure disorder
• have an irregular menstrual cycle
• have acquired disturbances of color vision
• have history of venous or arterial thrombosis (blood clot in artery/veins)
• have deep vein thrombosis, cerebral thrombosis (blood clot of cerebral vein in brain)
• have subarachnoid hemorrhage (bleeding in space between brain and tissue covering the brain)
• have blood in urine between periods

Before taking PURELITE 250MG TABLET inform your physician if you:

• have changes in normal bleeding pattern
• have family history of endometrial cancer
• have abnormal bleeding between the periods
• have bleeding during or after sexual intercourse
• have premenstrual pain or lower abdominal pain
• have bleeding after menopause
• have obstruction of the urinary tract
• are at a risk for the formation of a blood clot
• are diabetic
• are overweight
• have polycystic ovary syndrome (PCOS)

Use in pediatrics:

Safety and effectiveness of PURELITE 250MG TABLET in children and adolescents
below 18 years of age has not been established yet. Consult your child’s doctor
for advice.

Use in geriatrics:

PURELITE 250MG TABLET is not recommended for use in elderly women after
menopause (stoppage of periods). Consult your doctor before taking PURELITE
250MG TABLET.

Interactions

A. Drug-Drug interactions:

Before taking PURELITE 250MG TABLET inform your doctor if you are taking any of
the following medicines:

• Ethinyl estradiol, levonorgestrel (oral contrace
• estrogen (used to manage hormone disorder)
• streptokinase, reteplase, tenecteplase (used to a breakdown blood clots)
• tamoxifen (used to manage breast cancer)
• trans-retinoic acid (used to manage acne)
• factor IX complex concentrates (used to stop bleeding)

Overdosage:

If you or anyone else accidentally takes too much of PURELITE 250MG TABLET,
contact your doctor immediately or visit a nearby hospital immediately.
Overdosage symptoms of PURELITE 250MG TABLET are headache, nausea, vomiting,
diarrhea, abnormal blood pressure, impaired vision, abnormal mental status, skin
rashes, dizziness and fits or seizures.

Synopsis

Drug	:	Tranexamic Acid
Pharmacological Category	:	Antifibrinolytics
Therapeutic Indication	:	Prevent and manages bleeding in various conditions
Dosage Forms	:	Tablet, Gel, Injection

More Information

• Keep out of reach from children
• Store at room temperature

FAQs About PURELITE 250MG TABLET

Is PURELITE 250MG TABLET safe for use in patients with impaired kidney
function?

PURELITE 250MG TABLET is not recommended for use in patients with severe kidney
impairment.  PURELITE 250MG TABLET should be used with caution in patients with
mild to moderate kidney impairment and your doctor may adjust the dose depending
upon kidney function. Consult your doctor for advice before taking PURELITE
250MG TABLET.

Does PURELITE 250MG TABLET cause loose stools?

PURELITE 250MG TABLET can cause side effects such as loose stools. To manage
this effect, drink lot of fluids, such as water to keep yourself hydrated. Avoid
eating high-fat or spicy foods. Try to avoid taking any medicine on your own to
manage diarrhea and consult your doctor if the symptom gets worse.

Is PURELITE 250MG TABLET used for heavy menstrual bleeding?

PURELITE 250MG TABLET is used only when your periods are regular to control
heavy menstrual bleeding. It reduces the amount of blood lost during your period
but may not help other symptoms such as period pain. Do not take this medicine
if your periods are not heavy. Consult your doctor before taking PURELITE 250MG
TABLET.

What are the common side effects of PURELITE 250MG TABLET?

The most common side effects of taking PURELITE 250MG TABLET are nausea,
vomiting, diarrhea, headache, tiredness, muscle cramps, migraine, anemia (lack
of red blood cells), stomach pain, sinus and nasal symptoms. Consult your doctor
immediately if any of the side effect worsens.

Can PURELITE 250MG TABLET be used in pregnant women?

PURELITE 250MG TABLET should be used with caution in pregnant women only if
clearly advised by the doctor. Inform your doctor immediately if you become
pregnant or think you may be pregnant before taking PURELITE 250MG TABLET.

Useful Diagnostic Tests

• Complete blood count
• kidney function test
• Bleeding time/clotting time
• Urine analysis