PANTOP HP KIT 7'S

Introduction About PANTOP HP

PANTOP HP is a combination of Clarithromycin, Pantoprazole and Amoxicillin which
belongs to the group of medicines called Antibiotics and Antiulcer agents. It is
used to eradicate a bacteria called Helicobacter pylori in patients with active
chronic gastritis, stomach and intestinal ulcers.

Along management with PANTOP HP your doctor might want you to make some
lifestyle changes such as eating less spicy foods. Before starting the
management with PANTOP HP your doctor might ask you to take some diagnostic
tests to understand the existing condition.

Before taking PANTOP HP inform your doctor if you have liver, kidney or heart
disease. PANTOP HP should be taken with caution in patients having fungal
infections, glandular fever, problems in urinating, joint pains and due to take
Chromogr

PANTOP HP should be used with caution in pregnant and breast-feeding women. The
most common side effects of taking PANTOP HP are nausea, vomiting, diarrhea,
vomiting, indigestion and dry mouth. Talk to your doctor if any of these worsen
or doesn’t improve.

Uses Of PANTOP HP

• Eradicates Helicobacter pylori in patients with active chronic gastritis, stomach and intestinal ulcers

How PANTOP HP Works

PANTOP HP effectively eradicates H. Pylori and manages ulcers, where
Clarithromycin which belongs to a group of medicine called macrolide antibiotics
which enters the bacteria and stop its growth thus relieving the infection.
Amoxicillin is a penicillin antibiotic which interferes with the important life
cycle of the bacteria leading to its destruction. Pantoprazole is a selective
proton pump inhibitor, which acts on the cells present in the lining of the
stomach and reduces the amount of acid produced in the stomach.

How to use PANTOP HP

Take PANTOP HP as advised by your physician. Swallow the medicine with a glass
of water. Do not crush or chew the medicine. Your doctor will decide the correct
dose and duration of PANTOP HP for you depending upon your age, body weight and
disease condition.

Side Effects Of PANTOP HP

Common

• headache
• nausea, vomiting
• abdominal pain
• diarrhoea, constipation
• indigestion, heartburn
• dry mouth
• benign polyps in the stomach
• skin rash, discomfort

How To Manage Side Effects

Headache:

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to
be relaxed and stress free. Apply pain relieving balm on your forehead if
necessary. Consult your doctor if the symptom does not improve.

Stomach pain:

Try to rest and relax. Eat and drink slow or try to have smaller and frequent
meals. Keep a heat pad on your stomach. If the symptom does not improve, contact
your doctor.

Constipation:

Try to eat more high-fiber foods such as fresh fruit, vegetables, cereals and
drink plenty of water. If this does not help, inform your doctor for receiving
alternate management for constipation.

Diarrhoea:

Drink lot of fluids such as water to keep yourself hydrated. Avoid eating
high-fat or spicy foods. Inform your doctor if the symptom gets worse.

Dry mouth:

Sip water regularly and other sugar free liquids. Do not use mouthwashes that
contain alcohol because they can make your mouth dry, use mouthwash that is used
only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco
products. Consult your doctor if the symptom does not improve.

Warning & Precautions

!### Pregnancy

PANTOP HP should be used with caution in pregnant women. Consult your doctor
before taking it.

!### Breastfeeding

PANTOP HP should be used with caution in breastfeeding women. Consult your
doctor before taking it.

!### Driving and Using Machines

Do not drive or operate any machines if you feel dizzy or disturbed vision after
taking PANTOP HP.

!### Kidney

PANTOP HP should be used with caution in patients with kidney problems. Consult
your doctor before taking PANTOP HP.

!### Liver

PANTOP HP is not recommended for use in patients with severe liver disease. It
should be used with caution in patients with other liver disease. Consult your
doctor before taking PANTOP HP.

!### Allergy

Do not take PANTOP HP if you are allergic to Clarithromycin, Pantoprazole or
Amoxicillin.

!### Heart Disease

PANTOP HP is not recommended for use in patients having heart rhythm disorders.
It should be used with caution in patients with heart problems such as heart
failure, an unusually slow heart rate. Consult your doctor before taking PANTOP
HP.

Others

Before taking PANTOP HP, inform your doctor if you:

• have fungal infections
• have glandular fever (sore throat, fever, swollen glands and extreme tiredness)
• have problems in urinating
• have joint pain
• are due to have blood test called Chromogr
• have reduced Vitamin B12
• have rashes in areas exposed to sun

Use in Paediatrics:

Your child’s doctor will advise the correct dose and duration of PANTOP HP
depending upon the child’s age, weight and disease condition.

Use in Geriatrics:

Your doctor will advise the correct dose and duration of PANTOP HP for you
depending upon your age, disease condition and body weight.

Interactions

A. Drug – Drug Interactions:

Before taking PANTOP HP, inform your doctor if you are taking any of the
following medicines:

• medicines used for the management of heart problems (Ex. digoxin, disopyramide, quinidine), lower cholesterol (Ex. atorvastatin, rosuvastatin), high blood pressure (Ex. verapamil, amlodipine, diltiazem)
• medicines used for the management of epilepsy (Ex. carbamazepine, valproate, phenobarbital, phenytoin)
• medicines used in patients with breathing difficulties such as asthma (Ex. theophylline)
• sedatives (Ex. triazolam, alprazolam or midazolam)
• medicines used to manage poor circulation (Ex. cilostazol)
• corticosteroid (Ex. methylprednisolone) (used to manage inflammatory condition)
• medicines used for thinning the blood (Ex. warfarin, dabigatran, rivaroxaban, apixaban)
• medicines used to lower blood glucose levels (Ex. nateglinide, pioglitazone, repaglinide, rosiglitazone, gliclazide, glimepiride, insulin)
• medicines used for management of cancer (Ex. vinblastine, erlotinib)
• immune suppressants (Ex. ciclosporin, sirolimus, tacrolimus) (used to manage organ rejection after transplant)
• medicines used in the management of HIV (Ex. ritonavir, efavirenz, etravirine, nevirapine, zidovudine, atazanavir, saquinavir)
• medicines used for management of certain bacterial infections (Ex. rifampicin, rifapentine, rifabutin, lincomycin)
• fluconazole, itraconazole, clindamycin, ketoconazole, itraconazole, posaconazole (used to manage fungal infections)
• medicines used for managing overactive bladder (Ex. tolterodine)
• medicines used for impotence in adult males or for use in pulmonary arterial hypertension (Ex. sildenafil, vardenafil, tadalafil)
• herbal product used to manage depression (Ex. St John’s Wort)
• medicine used to manage rheumatoid arthritis, psoriasis and cancer (Ex. methotrexate)
• medicine used to manage depression and other psychiatric diseases (Ex. fluvoxamine)
• medicines used to manage gout (Ex. probenecid, allopurinol)

Overdosage:

If you or anyone else accidentally take too much of PANTOP HP, consult your
doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Clarithromycin, Pantoprazole and Amoxicillin
Pharmacological Category	:	Macrolides, Proton Pump Inhibitors, Penicillin
Therapeutic Indication	:	Eradicates Helicobacter pylori with active chronic gastritis, stomach and intestinal ulcers
Dosage Forms	:	Tablet

More Information

• Keep PANTOP HP out of reach of children
• Store at room temperature

FAQs About PANTOP HP

Q: What is PANTOP HP and why is it given?

A: PANTOP HP is a combination of Clarithromycin, Pantoprazole and Amoxicillin
which belongs to the group of medicines called Antibiotics and Antiulcer agents.
It is used to eradicate a bacteria called Helicobacter pylori in patients with
active chronic gastritis, stomach and intestinal ulcers.

Q: Can PANTOP HP cause diarrhoea?

A: Diarrhoea is a common side effect of taking PANTOP HP. For symptomatic
relief, drink lot of fluids such as water, squash or fruit juice to keep
yourself hydrated. Do not consume any medicine by yourself without consulting
your doctor.Q:Is PANTOP HP safe for pregnant and breast-feeding women?

A: PANTOP HP should be used with caution in pregnant women and breast-feeding
mother. Ask for your doctor’s advice before taking PANTOP HP if you are
pregnant, planning to get pregnant and breast-feeding your child.

Q:For how long should I take PANTOP HP?

A: Take PANTOP HP for as long as your doctor has prescribed for you. It depends
on your specific condition, age and body weight. Do not stop taking without the
doctor’s consultation and do not take it for prolonged periods as well.

Q: What should I tell my doctor before taking PANTOP HP?

A: Before taking PANTOP HP inform your doctor if you have any liver, kidney or
heart disease, fungal infections, glandular fever (sore throat, fever, swollen
glands and extreme tiredness), problems in urination, joint pain, due to have
Chromogr

Useful Diagnostic Tests

• Endoscopy
• Complete Blood Count