P & F 650mg Tablet 10'S

Introduction About P & F 650MG TABLET

P & F 650MG TABLET contains Paracetamol which belongs to the group of medicines
called Analgesics and Antipyretics. It is used to relieve mild to moderate pain
(including headaches, backache, toothache, severe nerve pain, sore throat,
period pain, low back and leg pain, muscle, connective tissue and joint pain,
symptomatic relief of sprains, strain, joint swelling and stiffness). It is also
used to lower fever (high body temperature) and relieves the symptoms of cold or
flu.

Before taking P & F 650MG TABLET, inform your doctor if you or your child have
liver or kidney problems or any allergies. It should be used with caution in
patients with liver problems due to alcohol to manage the risk of liver damage.

P & F 650MG TABLET should be used with caution in pregnant women only if clearly
advised by the doctor and can be used in breastfeeding women. P & F 650MG TABLET
is not recommended for use in children less than 10 years of age and should be
used with caution in elderly patients.

Consult your doctor if you experience any side effects or unusual effects during
management with P & F 650MG TABLET.

Uses Of P & F 650MG TABLET

• relieves mild to moderate pain (such as headache, toothache, joint pain)
• lowers fever and relieves the symptoms of cold or flu

How P & F 650MG TABLET Works

P & F 650MG TABLET relieves pain by increasing the pain threshold by inhibiting
certain enzymes (COX-1 and COX-2) involved in the synthesis of chemicals
responsible for inducing pain (prostaglandins). It reduces fever by directly
acting on heat-regulating centers in the brain, resulting in vessel relaxation,
sweating and loss of body heat.

How to use P & F 650MG TABLET

Take P & F 650MG TABLET as advised by your physician. It can be taken with or
without food.

For Tablet, Capsule: Swallow P & F 650MG TABLET with a glass of water. Do
not crush or chew the medicine.

For Dispersible Tablet: Disperse the medicine in the specified quantity of
water as mentioned in the label. Consume the medicine immediately after
reconstitution.

Your doctor will decide the correct dose and duration of therapy for you
depending upon your age, body weight and severity of the condition.

Side Effects Of P & F 650MG TABLET

Rare

• reduced white blood cells (infections are more likely to occur)

Stop taking P & F 650MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• allergic reaction (swelling of the hands, feet, ankles, face, lips or throat which may cause trouble swallowing or breathing, an itchy, lumpy rash or nettle rash, runny nose)

Warning & Precautions

!### Pregnancy

P & F 650MG TABLET should be used with caution in pregnant women only if
considered clearly necessary. Your doctor may use the lowest possible dose to
reduce the pain and fever only for a shorter duration in pregnant women. Consult
your doctor before taking P & F 650MG TABLET.

!### Breastfeeding

P & F 650MG TABLET should be used with caution in breastfeeding women. Consult
your doctor before taking it.

!### Driving and Using Machines

P & F 650MG TABLET has no influence on the ability to drive and operate
machinery.

!### Alcohol

P & F 650MG TABLET should be used with caution in patients with chronic
alcoholism. Consult your doctor before taking it.

!### Kidney

P & F 650MG TABLET should be used with caution in patients with severe kidney
problems. Consult your doctor before taking it.

!### Liver

P & F 650MG TABLET should be used with caution in patients with severe liver
problems or liver problems due to alcohol. Consult your doctor before taking it.

!### Allergy

Do not take P & F 650MG TABLET if you are allergic to Paracetamol or any other
ingredients of this medicine.

Others

Before taking P & F 650MG TABLET, inform your doctor if you:

• have sepsis (circulation of bacteria and their toxins in the blood leading to organ damage)
• are malnourished

Use in pediatrics:

P & F 650MG TABLET is not recommended for use in children less than 10 years of
age. It can be used in children and adolescents aged above 10 and your child’s
doctor may adjust the dose based on the child’s age and body weight. Consult
your child’s doctor for advice.

Use in geriatrics:

P & F 650MG TABLET should be used with caution in elderly patients. Consult your
doctor before taking it.

Interactions

A. Drug - Drug interactions:

Before taking P & F 650MG TABLET, inform your doctor if you are taking any of
the following medicines:

• other medicines containing paracetamol
• medicines to manage nausea and vomiting (Ex. metoclopramide, domperidone)
• cholestyramine (used to control blood lipid levels)
• warfarin (used for managing blood clots)
• medicines used to manage bacterial infections (Ex. rifampicin, flucloxacillin, chloramphenicol)

Overdosage:

If you or anyone else accidentally takes too much of P & F 650MG TABLET, consult
your doctor immediately or visit the nearby hospital, even if you feel well, as
it can cause delayed, serious liver damage.

Synopsis

Drug	:	Paracetamol
Pharmacological Category	:	Para aminophenol derivative
Therapeutic Indication	:	Pain, Fever
Dosage Forms	:	Tablet, Dispersible tablet, Drops, Syrup, Oral suspension, Liquid, Oral solution, Suppositories, Infusion, Injection

More Information

• Keep P & F 650MG TABLET out of reach of children
• Store below 25°C

FAQs About P & F 650MG TABLET

Q: What is the use of P & F 650MG TABLET?

A: P & F 650MG TABLET is commonly used to relieve mild to moderate pain and
reduce fever. It contains paracetamol (acetaminophen) and is often used for
conditions like headaches, muscle aches, toothaches, associated with various
illnesses.

Q: What happens if I take P & F 650MG TABLET?

A: P & F 650MG TABLET contains a medicine called paracetamol which is an
analgesic and antipyretic agent. Following administration, it works by blocking
the release of certain chemicals called prostaglandins in the body which is
responsible for causing pain and inflammation. Paracetamol also manages the
release of such chemicals in the hypothalamus of the brain which helps in
controlling fever.

Q: Can I take two doses of P & F 650MG TABLET in a day?

A: The dosage of P & F 650MG TABLET is decided by your physician. However,
studies have shown that taking paracetamol once in every 4-6 hours significantly
reduced fever and body pains.

Q: Can we use P & F 650MG TABLET for cold?

A: P & F 650MG TABLET could be used in the management of sore throat and body
pains that is associated with common cold. It contains a medicine called
paracetamol which is commonly used to relieve mild to moderate pain, like
headaches, muscle aches, toothaches, and fever associated with various
illnesses.

Q. Can I take P & F 650MG TABLET as often as required?

A: The dosage of P & F 650MG TABLET and duration of the therapy would be decided
by your doctor. It is usually not recommended to take more than 4 doses of P & F
650MG TABLET in a day. Leave a time gap of 4-6 hours, between each dose.

Q: Is P & F 650MG TABLET a strong medicine?

A: P & F 650MG TABLET is relatively an effective medicine in controlling fever
and body pain. It is typically used for mild to moderate pain relief and fever
reduction. However, it should be used as directed, and exceeding the recommended
dosage can lead to adverse effects.

Q: When would P & F 650MG TABLET start working?

A: It takes around 30 minutes for you to feel better after taking P & F 650MG
TABLET.

Q: Can I take P & F 650MG TABLET and ibuprofen together?

A: It is generally advisable to avoid taking P & F 650MG TABLET (paracetamol)
and ibuprofen together unless recommended by a healthcare professional. Mixing
these medications can increase the risk of side effects and potential harm to
the liver and stomach.

Q: When should we discontinue the use of Paracetamol?

A: Discontinue the use of Paracetamol if you experience allergic reactions,
severe skin reactions, liver problems, or if you consume alcohol regularly.
Always consult a healthcare professional if you have concerns or experience
adverse effects.

Q: Is P & F 650MG TABLET an antibiotic?

No. P & F 650MG TABLET is an analgesic and antipyretic medicine. It works by
reducing fever and provides pain relief.

Q: What happens if I take more doses of P & F 650MG TABLET than recommended to me?

A: Taking more than the recommended doses of P & F 650MG TABLET may be harmful.
Studies have shown that the overdosage of paracetamol may affect your liver and
gastrointestinal tract. Symptoms of overdosage might include vomiting, loss of
appetite, stomach pain, paleness and nausea.

Q: Can P & F 650MG TABLET be used for a headache?

A: Yes. P & F 650MG TABLET can relieve your headache. It can also
symptomatically manage headaches, however, cannot manage the underlying cause.
If you experience recurrent headaches, please consult your doctor. In such
cases, avoid self-medication with over-the-counter pain killers.

Q: Can P & F 650MG TABLET be used during pregnancy?

A: P & F 650MG TABLET can be used during pregnancy, however not during the last
trimester as it could delay the onset of pain sensation. If necessary, you
should use the lowest possible dose that reduces your pain and/or your fever and
use it for the shortest time possible.

Q: What happens if I take Dolo 650 without fever?

A: Dolo 650 tablet is generally used for managing pain and fever, It can be used
without getting a fever in most cases, especially if you have headaches,
toothaches, or period cramps.

Useful Diagnostic Tests

• Complete blood count
• Liver function test