OSTOKIND 50mg Tablet 10's

Introduction About OSTOKIND 50MG TABLET

OSTOKIND 50MG TABLET contains Diacerein which belongs to the group of medicines
called Anthraquinones. It is used for the symptomatic management of functional
symptoms of osteoarthritis.

Osteoarthritis is a common progressive disorder affecting primarily weight
bearing joints (knee, hip), characterised by progressive destruction of
cartilage causing pain, limitation of motion, stiffness, deformity and
disability.

Prior to the management, your doctor may want you to take several blood tests to
understand your existing condition like liver disease.

Avoid taking alcohol with OSTOKIND 50MG TABLET as it may increase the risk of
liver damage. OSTOKIND 50MG TABLET is not recommended for use in patients having
liver or kidney disease, colitis or crohn’s disease, partial or complete
intestinal obstruction or abdominal pain with an unknown cause.

Inform your doctor, if you have kidney or urinary problems, history of diarrhea,
irritable bowel disease, rare hereditary diseases such as congenital
galactosemia, glucose or galactose malabsor

OSTOKIND 50MG TABLET is not recommended for use in pregnant and breastfeeding
women. Contact your doctor before taking.

OSTOKIND 50MG TABLET is not recommended for use in children and adolescents
under 15 years of age. Contact your doctor before taking.

OSTOKIND 50MG TABLET should be used with caution in elderly aged above 65 years.
Contact your doctor before taking.

The most common side effects of taking OSTOKIND 50MG TABLET are diarrhea, soft
stools, pain in abdomen, frequent bowel movements, flatulence, skin rash,
itching, and eczema. Contact your doctor if any of the side effects worsen.

Uses Of OSTOKIND 50MG TABLET

• Used for the symptomatic management of Osteoarthritis

How OSTOKIND 50MG TABLET Works

OSTOKIND 50MG TABLET works by blocking the chemicals (interleukin-1) causing
inflammation and destruction of cartilage in the body. It also stimulates the
production of certain chemicals called transforming growth factor-β (TGF-β)
which triggers chondrocyte proliferation and stimulates the production of
collagen and proteoglycan, glycosaminoglycans and hyaluronic acid. Therefore
OSTOKIND 50MG TABLET manages the cartilage destruction and improves symptoms in
patients with osteoarthritis.

How to use OSTOKIND 50MG TABLET

Take OSTOKIND 50MG TABLET as advised by your physician. Swallow the medicines
with a glass of water. Do not crush or chew the medicine. Your doctor will
decide the correct dose and duration for you depending upon your age, body
weight and disease condition.

Side Effects Of OSTOKIND 50MG TABLET

Common

• diarrhea
• soft stools
• pain in abdomen
• frequent bowel movements
• flatulence
• skin rash, itching, eczema

Uncommon

• increased liver enzymes

Rare

• pigmentation of colorectal mucosa (melanosis coli)

Stop taking OSTOKIND 50MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• diarrhea (risk of dehydration and hypokalemia)
• signs of liver disease such as increased liver enzyme, tiredness, and loss of appetite, jaundice (yellowish discoloration of skin and white of eyes), abdominal pain, nausea, vomiting, change in stool and urine colour, reduced consciousness, itchy skin

How To Manage Side Effects

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep you hydrated. Do not
take any medicine on your own for managing diarrhea. Contact your doctor if the
symptom did not improve.

Stomach pain:

Rest and relax. Try to have smaller meals but take frequently. Keep a heat pad
on your stomach. Do not self-manage and contact your doctor if the symptom did
not improve.

Flatulence:

Eat smaller meals but take frequently and exercise regularly. If the symptom
does not improve, contact your doctor.

Itchy skin:

Avoid hot showers because hot water can irritate the skin. Do not scratch the
affected area. Use sunscreen and protective clothing when outdoors. Regularly
use unscented moisturizers to soothe and hydrate the affected area. If the
symptom does not improve, contact your doctor.

Warning & Precautions

!### Pregnancy

OSTOKIND 50MG TABLET is generally not recommended for use in pregnant women.
Consult your doctor before taking.

!### Breastfeeding

OSTOKIND 50MG TABLET is generally not recommended for use in breastfeeding women
as it is not known if this medicine passes into breast milk. Consult your doctor
before taking.

!### Alcohol

Avoid consum
the risk of liver damage.

!### Kidney

OSTOKIND 50MG TABLET is not recommended for use in patients with severe kidney
disease. Consult your doctor before taking.

!### Liver

OSTOKIND 50MG TABLET is not recommended for use in patients with liver disease.
Consult your doctor before taking.

!### Allergy

Do not take OSTOKIND 50MG TABLET if you are allergic to Diacerein or any of the
other ingredients of this medicine.

Others

OSTOKIND 50MG TABLET is not recommended for use if you have:

• colitis or crohn’s disease
• partial or complete intestinal obstruction
• abdominal pain with an unknown cause
• rapidly progressive (worsening) hip osteoarthritis

Before taking OSTOKIND 50MG TABLET, inform your doctor if you have:

• urinary system problems
• irritable bowel disease
• rare hereditary diseases such as congenital galactosemia, glucose or galactose malabsor

Use in pediatrics:

OSTOKIND 50MG TABLET is generally not recommended for use in children and
adolescents under 15 years of age. Consult your doctor before taking.

Use in geriatrics:

OSTOKIND 50MG TABLET is not recommended for use in elderly patients aged above
65 years. Consult your doctor before taking.

Interactions

A. Drug - Drug interactions:

Before taking OSTOKIND 50MG TABLET, inform your doctor if you are taking any of
the following medicine:

• laxatives (medicines used to manage constipation)
• antacids (Ex. Aluminium hydroxide, magnesium hydroxide or calcium hydroxide) (medicines used to manage acidity)
• diuretics (medicines used for hypertension)
• digoxin, digitoxin (medicines used for heart failure)
• amoxicillin/clavul
• chemotherapy (medicines used to manage cancer)

Overdosage:

If you or anyone else accidentally takes too much of OSTOKIND 50MG TABLET,
consult your doctor immediately or visit the nearby hospital. Symptoms of
overdose are diarrhea.

Synopsis

Drug	:	Diacerein
Pharmacological Category	:	Anthraquinones
Therapeutic Indication	:	Osteoarthritis
Dosage Forms	:	Tablet, Capsule

More Information

• Keep OSTOKIND 50MG TABLET out of the sight and reach of children
• Store OSTOKIND 50MG TABLET below 25°C

FAQs About OSTOKIND 50MG TABLET

Is OSTOKIND 50MG TABLET a painkiller?

No. OSTOKIND 50MG TABLET belongs to a group of medicines called Anthraquinones
with mild anti-inflammatory and anti-catabolic properties. Contact your doctor
before taking.

What is OSTOKIND 50MG TABLET is used for?

OSTOKIND 50MG TABLET is used for the symptomatic management of functional
symptoms of osteoarthritis.

Who should avoid taking OSTOKIND 50MG TABLET?

OSTOKIND 50MG TABLET is avoided in patients with liver or kidney disease,
colitis or crohn’s disease, partial or complete intestinal obstruction or
abdominal pain with an unknown cause, rapidly progressive osteoarthritis of hip,
allergic to OSTOKIND 50MG TABLET or rhein, pregnant or lactating women, children
and elderly patients. Consult your doctor before taking.

Can I take alcohol while using OSTOKIND 50MG TABLET?

No. Do not take alcohol with OSTOKIND 50MG TABLET as it may increases the risk
of liver damage. Contact your doctor before taking.

What are the side effects of OSTOKIND 50MG TABLET?

The most common side effects of taking OSTOKIND 50MG TABLET are diarrhea, soft
stools, pain in abdomen, frequent bowel movements, flatulence, skin rash,
itching, and eczema.

How OSTOKIND 50MG TABLET works?

OSTOKIND 50MG TABLET belongs to proteoglycan synthesis stimulator which works by
building cartilage (soft connective tissue around the joints) leading to joint
repair. It also lowers pain and inflammation (swelling).

Does OSTOKIND 50MG TABLET cause liver damage?

Yes. OSTOKIND 50MG TABLET may increase the risk of liver injury. If you
experience any unusual symptoms like tiredness, anorexia, yellowish
discoloration of skin and white of eyes (jaundice), abdominal pain, nausea,
vomiting, change in stool and urine colour, itchy skin. Stop taking OSTOKIND
50MG TABLET and immediately consult your doctor.

Useful Diagnostic Tests

• Calcium
• Rheumatoid Factor IgG Antibody
• Rheumatoid Factor IgM Antibody