OSON T Tablet 10's

Introduction About OSON T TABLET

OSON T TABLET contains a combination of Ofloxacin and Tinidazole, which belongs
to the group of antibiotic medicines called Fluoroquinolone and Nitroimidazole
(anti amoebic agent). OSON T TABLET is used in the management of diseases caused
by bacteria and parasites. It is used to manage diseases such as giardiasis
(parasitic infection of the intestine), amebiasis (a parasitic infection causing
dysentery), vaginal infection, infection in the kidney or urinary bladder,
respiratory infection etc. Symptoms of infection include fever, chills,
tiredness, vomit, stomach upset etc.

Ofloxacin kills and manages the growth of the bacteria by blocking DNA enzymes.
Tinidazole kills and manages the growth of the bacteria by reducing the nitro
group which causes DNA destruction. Your doctor may advise you to take relevant
medical tests to understand your existing condition.

OSON T TABLET is not recommended for use in patients having genetic disorders
(such as Cockayne syndrome, G6PD deficiency), fits or seizures, tendon muscle
weakness following antibiotic management etc. Also before taking OSON T TABLET
inform your doctor if have diabetes (abnormal body sugar level), abnormal blood
pressure, heart disease (such as irregular heartbeat, heart attack, valve
disorder, poor heart function etc.), kidney diseases (such as kidney failure or
kidney injury), inflammation of the intestine, severe skin problems (such as
Stevens-Johnson syndrome, toxic epidermal necrolysis, Marfan syndrome, Turner
syndrome etc.), muscle-weakening diseases (such as myasthenia gravis etc.),
nerve pain (neuropathy), liver disease, psychiatric illness or emotional
imbalances etc. It is not recommended for use in pregnant women or breastfeeding
mothers, consult your doctor for advice. The most common side effects of taking
OSON T TABLET may include changes in taste sensation (metallic/bitter), feeling
sick, weakness, stomach upset, vomiting, gaining weight, headache, dizziness,
difficulty in sleeping, itching, diarrhea (loose stools) or constipation (hard
stools) etc. Contact your doctor if any of the symptoms worsen.

Uses Of OSON T TABLET

OSON T TABLET is used in the management of diseases caused by bacteria and
parasites such as:

• giardiasis (parasitic infection of the intestine)
• amebiasis (a parasitic infection causing dysentery)
• vaginal infection caused by bacteria
• infection in the kidney or urinary bladder
• diarrhea
• respiratory infection etc.

How OSON T TABLET Works

Ofloxacin kills and manages the growth of the bacteria by blocking DNA enzymes.
Tinidazole kills and manages the growth of the bacteria by reducing the nitro
group which causes DNA destruction.

How to use OSON T TABLET

Always take OSON T TABLET as directed by your physician. Swallow the medicine as
a whole and do not crush or chew the medicine. Your doctor will decide the
correct dose, duration, and frequency depending on your age, body weight and
other comorbid conditions, etc.

Side Effects Of OSON T TABLET

Common

• feeling sick
• vomiting
• changes in taste sensation (metallic/bitter)
• weakness
• diarrhea (loose stools) or constipation (hard stools)
• stomach upset or discomfort
• gaining weight
• headache
• dizziness
• difficulty in sleeping
• itching of skin etc.

Uncommon

• stomach pain
• restlessness
• anxiety
• itching or burning sensation of the eye
• cough
• sore throat or nose
• skin rashes
• itching sensation of skin

Rare

• severe diarrhea with bloody stools
• swelling of tendon muscles
• tingling sensation or numbness
• impaired vision
• drowsiness, lightheadedness
• excessive sweating
• fever with high fever
• loss of appetite
• depression, emotional imbalance, nightmares or hearing things not there
• confusion
• difficulty in breathing
• loss or changes in sensation of taste and smell
• abnormal heartbeat
• elevated liver enzymes
• redness, itching and skin rashes
• pimples

Stop taking OSON T TABLET and contact your doctor immediately if you experience
any of the following side effects:

• severe allergic reactions (such as skin rash, itching, swelling of the face, lips, tongue and other parts of the body, difficulty in breathing or wheezing, blisters on the skin, sore throat, fever, headache etc.)
• painful skin rashes with blisters and peeling or scaling of skin in conditions such as steven-johnson syndrome, toxic epidural necrolysis etc.
• abnormal heartbeat
• changes in behavior, psychosis, depression, hallucination, disorientation or fainting etc.
• impaired vision or hearing
• severe fever, body chills or muscle pain
• swelling or rupture of tendons and muscles, muscle paralysis
• numbness, tingling sensation of the skin
• abnormal bleeding along with the stools or urine
• abnormal body movements like fits of seizure
• severe loose stools (diarrhea) with or without blood
• difficulty in passing urine or discoloration of urine
• loss of consciousness
• severe stomach pain
• fever with high temperature
• abnormal body sugar level
• pain, burning, tingling, numbness and/or weakness especially in the feet and legs or hands and arms which indicates nerve damage
• severe stomach pain, itching, dark urine or yellowish discoloration of the skin and in the white part of the eye (jaundice) etc.
• pale discoloration of the skin, fainting, dizziness, difficulty in breathing
• low WBC cells or platelets

How To Manage Side Effects

!### Diarrhea

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated.
Consult your doctor immediately if the symptoms worsen or persist.

Headache

Take rest and get adequate sleep, stay hydrated. Consult your doctor immediately
if the symptoms persist or worsen.

!### Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Avoid
eating rich or spicy food.

!### Stomach Pain

Try to rest and relax. Eat and drink slowly or try to have smaller and frequent
meals. Keep a heating pad on your stomach. If the symptom does not improve,
contact your doctor.

Warning & Precautions

!### Pregnancy

ContraindicatedOSON T TABLET is not recommended for use in pregnant women. Consult your doctor
before taking it.

!### Breastfeeding

ContraindicatedOSON T TABLET is not recommended for use in breastfeeding mothers. Consult your
doctor before taking it.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines after taking OSON T TABLET if you feel
dizzy, tired, sleepy, loss of consciousness, less alert etc.

!### Alcohol

Consult your doctorAvoid consum
existing condition and cause stomach pain, sickness, headache, flushing etc.

!### Kidney

Use with CautionOSON T TABLET should be taken with caution in patients with kidney disease or
conditions (such as difficulty urinating, kidney injury, kidney failure, kidney
transplant or undergoing dialysis management). Consult your doctor before
taking.

!### Liver

Use with CautionOSON T TABLET should be taken with caution in patients with liver disease (such
as hepatitis, jaundice, liver failure etc.). Consult your doctor before taking.

!### Allergy

ContraindicatedDo not take OSON T TABLET or consult your doctor if you are allergic to
Ofloxacin and/or Satr
other quinolone antibiotics such as ciprofloxacin, norfloxacin etc.

!### Lungs

Use with CautionOSON T TABLET should be taken with caution in patients with lung disease or
conditions (such as having undergone lung transplant etc.). Consult your doctor
before taking.

!### Heart Disease

Use with CautionOSON T TABLET should be taken with caution in patients with heart disease or
conditions (such as irregular heartbeat, heart attack, poor functioning of the
heart, heart transplant etc.). Consult your doctor before taking.

!### Use In Pediatrics

ContraindicatedOSON T TABLET is not recommended for use in children and adolescents less than
18 years old. Consult your doctor before taking.

!### Use In Geriatrics

Use with CautionOSON T TABLET should be used with caution in the elderly. Consult your doctor
before taking.

Others

OSON T TABLET is not recommended for use if you:

• genetic disorders (such as Cockayne syndrome, G6PD deficiency)
• fits or seizures
• tendon muscle weakness or rupture
• pain in the nerve etc.

Before taking OSON T TABLET, inform your physician if you have:

• diabetes
• abnormal blood pressure
• low RBC or hemoglobin level (anemia)
• severe or recurrent dysentery/loose stools
• severe skin diseases such as steven- johnson syndrome, toxic epidermal necrolysis, Marfan syndrome or Ehlers-Danlos syndrome, Turner syndrome, Sjogren’s syndrome etc.)
• autoimmune diseases such as rheumatoid arthritis etc.
• muscle-weakening diseases such as myasthenia gravis, rhabdomyolysis
• inflammation of the digestive system
• abnormal body movements like fits/seizures
• imbalance of body fluids
• abnormal bleeding or clotting of blood
• fungal infection involving the vagina
• electrolyte or salt imbalance such as low potassium or magnesium
• G6PD deficiency
• psychiatric/mental disease, emotional imbalances
• plans to take a medical test such as blood or urine test

Interactions

A. Drug-Drug interactions:

Inform your physician, that if you are having,

• warfarin, acenocoumarin, phenprocoumon - used to manage or manage blood clot
• probenecid – used to manage gout
• methotrexate – used to manage diseases like cancer, psoriasis, rheumatoid arthritis etc.
• ibuprofen or diclofenac – used to relieve pain and fever
• cyclosporin – used to manage skin disease, rheumatoid arthritis and organ transplantation
• quinidine, hydroquinidine, disopyramide, amiodarone, sotalol, dofetilide, ibutilide, pentoxifylline – used to manage heart diseases
• insulin, glyburide/glibenclamide – used to manage diabetes
• phenytoin, phenobarbital, fosphenytoin - used to manage epilepsy/fits or seizures
• lithium – used to manage depression
• theophylline- used to manage wheezing, asthma etc.
• erythromycin, clarithromycin, azithromycin – used to manage the bacterial infection
• didanosine – used in the management of HIV infection
• tacrolimus -  used to manage eczema, dermatitis etc.
• sucralfate – used to manage stomach acidity or stomach ulcer
• cimetidine – used to manage stomach ulcers, gastritis, stomach acid reflux etc.
• ketoconazole – used to manage fungal infection
• disulfiram - used to manage alcoholism
• fluorouracil - used to manage cancers
• Oxytetracycline – used to manage tetanus, gangrene etc.
• medicine or supplements containing zinc, calcium, magnesium, aluminum or iron
• herbal medicines

B. Drug-Food interaction:

OSON T TABLET may interact with caffeine-containing products (coffee, chocolates
etc.), grapefruit juice and foods rich in calcium, dairy products such as milk
as well as butter, yogurt, cheese etc. Consult your doctor for diet advice.

Overdosage:

If you or anyone else accidentally take too much of OSON T TABLET, consult your
doctor immediately or visit the nearby hospital if your experience is persistent
or worsening of any side effects.

Synopsis

Drug	:	Ofloxacin, Tinidazole
Pharmacological Category	:	Fluroquinolones and Nitroimidazoles
Therapeutic Indication	:	To manage bacterial and parasitic infection
Dosage Forms	:	Tablet, Syrup

More Information

• Keep out of reach from children
• Store at room temperature

FAQs About OSON T TABLET

Q: Can [GBBNKEYWORD] be used by pregnant women?

A: OSON T TABLET is not recommended for use in pregnant women. However, consult
your doctor for advice as your doctor may outweigh the risks and benefits during
life-threatening conditions.

Q: Can OSON T TABLET cause tendon weakness?

A: OSON T TABLET can increase the risk of tendon weakness or rupture. Stop
taking this medicine and/or consult your doctor immediately if you experience
symptoms like tendon pain in joints, swelling, hearing or feeling a snap or pop
in a tendon area, bruising right after an injury in a tendon area, unable to
move the affected area or bear weight etc.

Q: Can OSON T TABLET cause abnormal behavior?

A: OSON T TABLET is a combination of ofloxacin and tinidazole. The side effect
of ofloxacin includes changes in behavior, anxiety, nervousness, nightmares,
depression, emotional imbalance etc. Consult your doctor immediately if the
symptoms occur.

Q: Is OSON T TABLET safe for use in patients with heart disease?

A: OSON T TABLET should be used with caution in patients with heart disease such
as heart attack, myocardial infarction, poor functioning of the heart, abnormal
heartbeat etc. Also, inform your doctor if you have undergone a heart
transplant. Consult your doctor before use.

Q: Can OSON T TABLET cause headache?

A: The most common side effects of taking OSON T TABLET may include headache,
changes in taste sensation (metallic/bitter), feeling sick, weakness, stomach
upset, vomiting, gaining weight, dizziness, difficulty in sleeping, itching,
diarrhea (loose stools) or constipation (hard stools) etc. If you are
experiencing a headache, take rest and get adequate sleep and stay hydrated.
Consult your doctor immediately if any of the symptoms persist or worsen.

Useful Diagnostic Tests

• CBP
• LFT
• KFT
• Random blood glucose level
• Fasting blood glucose level
• HBA1c
• Oral glucose tolerance test
• Capillary blood glucose (home monitoring)
• TSH
• PT -INR
• BT/CT - test
• Urine test for blood sugar (glucose)
• Stool examination test
• USG abdomen
• MRI, CT scan
• Urinary analysis
• Culture sensitivity test