OMNITOP D Capsule 10's

Introduction About OMNITOP D CAPSULE

OMNITOP D CAPSULE is a combination of Domperidone and Omeprazole which belongs
to the group of medicines called Prokinetic Drugs and Proton pump inhibitors
respectively. It is used to manage pe
disease (GERD) and Zollinger-Ellison syndrome (tumours in pancreas causing the
stomach to secrete more acid).

OMNITOP D CAPSULE is effective in managing pe
stomach infection (H. pylori infection) or due to prolong use of non-steroidal
anti-inflammatory drugs (such as ibuprofen, aceclofenac). OMNITOP D CAPSULEacts
by reducing the production of gastric acid. It also speeds up the movement of
food from the stomach to the intestines, thereby reducing the signs of nausea,
vomiting and acid reflux. Due to these actions, it can also reduce the
unpleasant signs of GI tract such as nausea, vomiting, indigestion, burping,
bloating, acidity or heartburn. OMNITOP D CAPSULEis suitable for use both in
adults and in children (aged 12 years or above weighing 35 kg or more). It
should be taken at least 15-30 minutes before meals. During management with
OMNITOP D CAPSULEyour doctor will closely monitor your kidney functions, liver
functions and blood magnesium levels to avoid the risk of unwanted side effects.

Before taking OMNITOP D CAPSULEinform your doctor if you have any liver, kidney
or heart problems. You must also inform your doctor if you have any blockage or
tears in the gut or have weak bones. OMNITOP D CAPSULEis not recommended for use
in patients having bleeding from the gut. Consult your doctor before taking
OMNITOP D CAPSULEif you are pregnant or breastfeeding. The most common side
effects of taking OMNITOP D CAPSULEare dryness of mouth, constipation and
flatulence. Consult your doctor if any of these side effect bothers you. You
must also inform your doctor immediately if you experience any abnormal signs
such as unusual tiredness, abnormal muscle movements, dizziness, confusion,
disorientation, irregular heartbeat, fragile bones, bloody stools or vomits or
sudden weight loss.

Uses Of OMNITOP D CAPSULE

It is used in adults and in children (aged 12 years or older weighing 35 kg or
more) to manage:

• Pe
• Gastrointestinal Reflux disease (GERD)
• Zollinger-Ellison syndrome (tumours in pancreas causing the stomach to secrete more acid)
• Nausea and Vomiting
• Acidity, Heartburn, Indigestion, Burping, Bloating

How OMNITOP D CAPSULE Works

OMNITOP D CAPSULE contains two medicines namely domperidone and omeprazole.
Domperidone works by blocking the actions of a chemical messenger called
dopamine in the gut and across the brain and spinal cord. This action stimulates
the gut, reduces acid reflux and speeds up the movements of food from the
stomach into the intestines. It also blocks the transmission of nerve signals
between the vomiting centres and the brain which reduces the onset of nausea and
vomiting. Omeprazole is a proton pump inhibitor. It reduces gastric acid
secretion by the blocking the actions of a protein membrane called H+K+Atpase
(proton pump) present in the lining of the stomach. By reducing stomach acid
production, OMNITOP D CAPSULEmanages the worsening of ulcers, heals the existing
ulcers and esophageal lesions and provides relief from the unpleasant symptoms
of GI tract (such as acidity, bloating, burping and indigestion).

How to use OMNITOP D CAPSULE

Take OMNITOP D CAPSULE15-30 minutes before meals or as advised by your
physician. Swallow the medicine with a glass of water. Do not crush or chew the
medicine. Your doctor will decide the correct dose and duration of therapy for
you depending upon your age, body weight and disease condition. Do not stop
taking OMNITOP D CAPSULEunless your doctor advice you to stop.

Side Effects Of OMNITOP D CAPSULE

Common

• headache
• diarrhea
• stomach pain
• constipation
• flatulence
• nausea
• vomiting
• benign polyps in the stomach
• dry mouth

Uncommon

• low sex drive
• dizziness
• anxiety
• sleeplessness
• skin rash or itchiness
• breast enlargement in both men and in women
• feeling weak
• swelling of body parts (oedema)
• fragile bones (risk of bone fracture)
• abnormal liver function tests

Rare

• low WBC or platelet counts in blood
• signs of low sodium levels in blood (weakness, being sick and cramps)
• mouth ulcers
• hair loss
• fungal infection of the gut (thrush)

Stop taking OMNITOP D CAPSULEand inform your doctor immediately if you
experience any of the following side effects such as:

• severe allergic reactions (such as skin rash, itching, swelling of the lips, face or body and difficulty in breathing or swallowing)
• signs of liver problems (yellowing of the skin and eyes, dark urine and tiredness)
• severe skin reactions (such as redness, blistering, peeling of skin and bleeding in the lips, eyes, mouth, nose and genitals with fever)
• chest pain, fast or irregular heartbeat, difficulty in breathing, feeling faint
• fits
• uncontrollable body movements (including eye and tongue), twisted neck and abnormal body posture
• signs of low magnesium levels in blood (such as tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat)
• skin rashes on sun exposed areas
• sudden weight loss, looking pale and weak (anemia)
• signs of bleeding in the gut (such as bloody vomits/stools)

How To Manage Side Effects

!### Constipation

Taking OMNITOP D CAPSULEwith meals may reduce the chances of constipation.
However, if you experience constipation, eat plenty of fiber rich foods such as
fresh fruits, vegetables and cereals. Drink plenty of fluids. Exercise more
regularly. Consult your doctor if this side effect bothers you.

!### Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or
machines completely while you are feeling dizzy. Do not consume excessive
alcohol, as it could aggravate your dizziness. Consult your doctor if your
dizziness worsens.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate your
headache. Consult your doctor if your headache worsens.

!### Nausea And Vomiting

Try to take OMNITOP D CAPSULEwith or just after meals. Stick to simple meals and
avoid oil rich or spicy foods. Consult your doctor if nausea worsens.

Warning & Precautions

!### Pregnancy

Monitoring requiredOMNITOP D CAPSULE should be used in pregnant women only if it is considered
necessary by the physician. Therefore, consult your doctor before taking it.

!### Breastfeeding

Monitoring requiredOMNITOP D CAPSULE may pass through breast milk. Therefore, it should be used in
breastfeeding women only if it is considered necessary by the physician. Consult
your doctor for advice.

!### Driving and Using Machines

Use with CautionOMNITOP D CAPSULE does not affect your ability in driving or handling heavy
tools or machines. However, do not drive or handle heavy tools or machines if
your ability is affected by OMNITOP D CAPSULE.

!### Alcohol

Consult your doctorAvoid consum
aggravate your existing condition.

!### Kidney

Use with CautionOMNITOP D CAPSULE should be used with caution in patients with kidney problems.
Therefore, consult your doctor before taking it.

!### Liver

Consult your doctorOMNITOP D CAPSULE is not recommended for use in patients with moderate or severe
liver impairment. It should be used with caution in patients with other mild
liver problems. Therefore, consult your doctor before taking it.

!### Allergy

ContraindicatedDo not take OMNITOP D CAPSULEif you are allergic to Domperidone, Omeprazole or
to any other proton pump inhibitors (such as rabeprazole, pantoprazole).

!### Heart Disease

ContraindicatedOMNITOP D CAPSULE is not recommended for use in patients with heart problems
such as prolongation of QT interval or congestive heart failure. Therefore,
consult your doctor before taking it.

!### Use In Pediatrics

ContraindicatedOMNITOP D CAPSULE should be used in children and adolescents (aged 12 years or
above, weighing 35kg or more). It is not recommended for use in children and
adolescents (aged below 12 years). However, consult your doctor before taking
it.

!### Use In Geriatrics

Use with CautionOMNITOP D CAPSULE should be used with caution in elderly patients (aged 65 years
and above). Therefore, consult your doctor before taking it.

Others

OMNITOP D CAPSULE is not recommended for use if you:

• have bloody stools or bleeding in the gut
• have blockage or tear in the intestines
• have severe fluid or electrolyte disturbances
• have prolactinoma (a non-cancerous tumor of pituitary gland)
• have low blood potassium or magnesium levels
• have hyperkalemia (high blood potassium levels)

Before taking OMNITOP D CAPSULEinform your doctor if you:

• have osteoporosis
• have vitamin B12 deficiency (sore tongue, mouth ulcers, pale skin, depression)
• are going to test Chromogr

Interactions

A. Drug-Drug interactions:

Before taking OMNITOP D CAPSULEinform your doctor if you are taking any of the
following medicines such as:

• other medicines used to manage gastrointestinal problems (Ex. cisapride, dolasetron, prucalopride, diphem
• medicines used to manage heart problems or hypertension (Ex. digoxin, apomorphine, disopyramide, hydroquinidine, quinidine, amiodarone, dofetilide, dronedarone, ibutilide, sotalol, diltiazem or verapamil)
• medicines used to manage HIV infection (Ex. atazanavir, nelfinavir, saquinavir)
• medicines used to manage fungal infections (such as ketoconazole, itraconazole, posaconazole)
• medicines used for blood thinning (Ex. warfarin and phenprocoumon)
• medicines used to manage hepatitis C infection (Ex. telaprevir)
• antipsychotics (used to manage mental illness) Ex. haloperidol, pimozide, sertindole
• antidepressants (used to manage depression) Ex. escitalopram or citalopram, fluvoxamine, St. John’s wort
• antibiotics (used to manage bacterial infections) Ex. moxifloxacin, erythromycin, levofloxacin, clarithromycin, telithromycin or amoxicillin
• medicines used to manage malaria (Ex. halofantrine, lumefantrine)
• antihistamines (used to manage allergies) Ex. mizolastine, mequitazine
• medicines used to manage cancer (Ex. toremifene, vandet
• methotrexate (a medicine used to manage cancer and auto-immune disease)
• bepridil (a medicine used to manage hypertension)
• methadone (a medicine used to relieve pain)
• diazepam (a medicine used to manage epilepsy, anxiety and to induce sleep)
• phenytoin (a medicine used to manage epilepsy)
• cilostazol (a medicine used to manage pain and spasms of calf muscles)
• clopidogrel (a medicine used to manage blood clots)
• tacrolimus or mycophenolate mofetil (used to manage graft rejection)
• pentamidine (a medicine used to manage parasite infections)
• rifampicin (a medicine used to manage tuberculosis)

Overdosage:

If you or anyone else accidentally took more OMNITOP D CAPSULE, contact your
doctor immediately or go to a hospital straight away. Symptoms of overdosage
might include sleepiness, confusion, uncontrollable body movements (including
eye and tongue), twisted neck and abnormal body posture.

Synopsis

Drug	:	Domperidone, Omeprazole
Pharmacological Category	:	Dopamine (D2) Receptor antagonists, Proton pump inhibitors
Therapeutic Indication	:	Pe
Dosage Forms	:	Tablet, Capsule

More Information

Storage

• Keep OMNITOP D CAPSULEout of the sight and reach of children
• Store OMNITOP D CAPSULEat room temperature

FAQs About OMNITOP D CAPSULE

Q: What is OMNITOP D CAPSULE used for?

A: OMNITOP D CAPSULE is used to manage pe
Syndrome. It can also be used to manage nausea, vomiting, bloating, burping,
acidity and heartburn.

Q: How and when to take OMNITOP D CAPSULE?

A: Take OMNITOP D CAPSULEat least 15-30 minutes before meals. Swallow the
medicine with a glass of water. Do not crush or chew the medicine. Your doctor
will decide the correct dose and duration of therapy for you depending upon your
age, body weight and disease condition.

Q: How long should I take OMNITOP D CAPSULE?

A: You need to take OMNITOP D CAPSULE for the stipulated duration prescribed by
your doctor. Your doctor will decide the correct dose and duration of therapy
for you depending upon your age, body weight and disease condition.

Q: What is the best time to take OMNITOP D CAPSULE?

A: OMNITOP D CAPSULEmust be taken before meals to avoid gastrointestinal side
effects.

Q: What to do if I forgot to take a dose of OMNITOP D CAPSULE?

A: If you forgot to take a dose of OMNITOP D CAPSULE, take it as soon as you
remember. However, if it is time for the next dose of OMNITOP D CAPSULE, skip
the missed dose and take the next one regularly. Do not take a double dose of
OMNITOP D CAPSULEto compensate the missed ones.

Q: What are the most common side effects of taking OMNITOP D CAPSULE?

A: The most common side effects of taking OMNITOP D CAPSULEare dryness of mouth,
constipation and flatulence. Consult your doctor if any of these side effect
bothers you.

Q: Can I stop taking OMNITOP D CAPSULE without consulting your doctor?

A: No. You should not stop taking OMNITOP D CAPSULE without consulting your
doctor because it may lead to reversal of symptoms. If you feel better after
using OMNITOP D CAPSULE, consult your doctor for advice.

Q: Will taking a higher dose of OMNITOP D CAPSULE be more effective?

A: No, taking a higher dose of OMNITOP D CAPSULE will not be effective rather it
can lead to toxicity. Always take the dose prescribed by your doctor. If the
prescribed dose is not effective for you, consult your doctor for advice. Your
doctor might increase the dose or suggest an alternative therapy.

Q: What precautions do I need to follow while taking OMNITOP D CAPSULE?

A: Make sure to take OMNITOP D CAPSULE 30 minutes before meals. Before taking
OMNITOP D CAPSULE inform your doctor if you have any liver, kidney or heart
problems. You must also inform your doctor if you have any blockage or tears in
the gut or have weak bones. Consult your doctor before taking OMNITOP D CAPSULE
if you are pregnant or breastfeeding. Regularly visit your doctor and take all
the blood tests recommended by your doctor without fail.

Q: Can I take medication for high blood pressure along with OMNITOP D CAPSULE?

A: It is not advisable to take medicines to control blood pressure while taking
OMNITOP D CAPSULE without consulting your doctor as they have known interactions
with OMNITOP D CAPSULE.

Q: Can OMNITOP D CAPSULE be used in pregnant women?

A: OMNITOP D CAPSULE should be used in pregnant women only if it is considered
necessary by the physician. Therefore, consult your doctor before taking it.

Q: How much OMNITOP D CAPSULE should I take?

A: OMNITOP D CAPSULE should be used only under medical supervision. Your doctor
will decide the correct dose and duration of therapy for you depending upon your
age, body condition and severity of the disease condition.

Q: Can OMNITOP D CAPSULE cause constipation?

A: Yes. Constipation is a common side effect of using OMNITOP D CAPSULE. Eat
plenty of fiber rich foods such as fresh fruits, vegetables, cereals as well as
drink plenty of water and exercise more regularly when taking this medicine.
Contact your doctor if this side effect bothers you.

Q: Can OMNITOP D CAPSULE cause dry mouth?

A: Yes. Dry mouth is a common side effect of using OMNITOP D CAPSULE. Contact
your doctor if this side effect bothers you.