Okaflox TZ 200/600mg Tablet 10'S

Introduction About OKAFLOX TZ 200/600MG TABLET

OKAFLOX TZ 200/600MG TABLET contains a combination of Ofloxacin and Tinidazole,
which belongs to the group of antibiotic medicines called Fluoroquinolone and
Nitroimidazole (anti amoebic agent). OKAFLOX TZ 200/600MG TABLET is used in the
management of diseases caused by bacteria and parasites. It is used to manage
diseases such as giardiasis (parasitic infection of the intestine), amebiasis (a
parasitic infection causing dysentery), vaginal infection, infection in the
kidney or urinary bladder, respiratory infection etc. Symptoms of infection
include fever, chills, tiredness, vomit, stomach upset etc.

Ofloxacin kills and manages the growth of the bacteria by blocking DNA enzymes.
Tinidazole kills and manages the growth of the bacteria by reducing the nitro
group which causes DNA destruction. Your doctor may advise you to take relevant
medical tests to understand your existing condition.

OKAFLOX TZ 200/600MG TABLET is not recommended for use in patients having
genetic disorders (such as Cockayne syndrome, G6PD deficiency), fits or
seizures, tendon muscle weakness following antibiotic management etc. Also
before taking OKAFLOX TZ 200/600MG TABLET inform your doctor if have diabetes
(abnormal body sugar level), abnormal blood pressure, heart disease (such as
irregular heartbeat, heart attack, valve disorder, poor heart function etc.),
kidney diseases (such as kidney failure or kidney injury), inflammation of the
intestine, severe skin problems (such as Stevens-Johnson syndrome, toxic
epidermal necrolysis, Marfan syndrome, Turner syndrome etc.), muscle-weakening
diseases (such as myasthenia gravis etc.), nerve pain (neuropathy), liver
disease, psychiatric illness or emotional imbalances etc. It is not recommended
for use in pregnant women or breastfeeding mothers, consult your doctor for
advice. The most common side effects of taking OKAFLOX TZ 200/600MG TABLET may
include changes in taste sensation (metallic/bitter), feeling sick, weakness,
stomach upset, vomiting, gaining weight, headache, dizziness, difficulty in
sleeping, itching, diarrhea (loose stools) or constipation (hard stools) etc.
Contact your doctor if any of the symptoms worsen.

Uses Of OKAFLOX TZ 200/600MG TABLET

OKAFLOX TZ 200/600MG TABLET is used in the management of diseases caused by
bacteria and parasites such as:

• giardiasis (parasitic infection of the intestine)
• amebiasis (a parasitic infection causing dysentery)
• vaginal infection caused by bacteria
• infection in the kidney or urinary bladder
• diarrhea
• respiratory infection etc.

How OKAFLOX TZ 200/600MG TABLET Works

Ofloxacin kills and manages the growth of the bacteria by blocking DNA enzymes.
Tinidazole kills and manages the growth of the bacteria by reducing the nitro
group which causes DNA destruction.

How to use OKAFLOX TZ 200/600MG TABLET

Always take OKAFLOX TZ 200/600MG TABLET as directed by your physician. Swallow
the medicine as a whole and do not crush or chew the medicine. Your doctor will
decide the correct dose, duration, and frequency depending on your age, body
weight and other comorbid conditions, etc.

Side Effects Of OKAFLOX TZ 200/600MG TABLET

Common

• feeling sick
• vomiting
• changes in taste sensation (metallic/bitter)
• weakness
• diarrhea (loose stools) or constipation (hard stools)
• stomach upset or discomfort
• gaining weight
• headache
• dizziness
• difficulty in sleeping
• itching of skin etc.

Uncommon

• stomach pain
• restlessness
• anxiety
• itching or burning sensation of the eye
• cough
• sore throat or nose
• skin rashes
• itching sensation of skin

Rare

• severe diarrhea with bloody stools
• swelling of tendon muscles
• tingling sensation or numbness
• impaired vision
• drowsiness, lightheadedness
• excessive sweating
• fever with high fever
• loss of appetite
• depression, emotional imbalance, nightmares or hearing things not there
• confusion
• difficulty in breathing
• loss or changes in sensation of taste and smell
• abnormal heartbeat
• elevated liver enzymes
• redness, itching and skin rashes
• pimples

Stop taking OKAFLOX TZ 200/600MG TABLET and contact your doctor immediately if
you experience any of the following side effects:

• severe allergic reactions (such as skin rash, itching, swelling of the face, lips, tongue and other parts of the body, difficulty in breathing or wheezing, blisters on the skin, sore throat, fever, headache etc.)
• painful skin rashes with blisters and peeling or scaling of skin in conditions such as steven-johnson syndrome, toxic epidural necrolysis etc.
• abnormal heartbeat
• changes in behavior, psychosis, depression, hallucination, disorientation or fainting etc.
• impaired vision or hearing
• severe fever, body chills or muscle pain
• swelling or rupture of tendons and muscles, muscle paralysis
• numbness, tingling sensation of the skin
• abnormal bleeding along with the stools or urine
• abnormal body movements like fits of seizure
• severe loose stools (diarrhea) with or without blood
• difficulty in passing urine or discoloration of urine
• loss of consciousness
• severe stomach pain
• fever with high temperature
• abnormal body sugar level
• pain, burning, tingling, numbness and/or weakness especially in the feet and legs or hands and arms which indicates nerve damage
• severe stomach pain, itching, dark urine or yellowish discoloration of the skin and in the white part of the eye (jaundice) etc.
• pale discoloration of the skin, fainting, dizziness, difficulty in breathing
• low WBC cells or platelets

How To Manage Side Effects

!### Diarrhea

Drink lots of fluids, such as water or fruit juice to keep yourself hydrated.
Consult your doctor immediately if the symptoms worsen or persist.

Headache

Take rest and get adequate sleep, stay hydrated. Consult your doctor immediately
if the symptoms persist or worsen.

!### Nausea And Vomiting

Take this medicine with, or just after meals. Stick to simple meals. Avoid
eating rich or spicy food.

!### Stomach Pain

Try to rest and relax. Eat and drink slowly or try to have smaller and frequent
meals. Keep a heating pad on your stomach. If the symptom does not improve,
contact your doctor.

Warning & Precautions

!### Pregnancy

ContraindicatedOKAFLOX TZ 200/600MG TABLET is not recommended for use in pregnant women.
Consult your doctor before taking it.

!### Breastfeeding

ContraindicatedOKAFLOX TZ 200/600MG TABLET is not recommended for use in breastfeeding mothers.
Consult your doctor before taking it.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines after taking OKAFLOX TZ 200/600MG TABLET if
you feel dizzy, tired, sleepy, loss of consciousness, less alert etc.

!### Alcohol

Consult your doctorAvoid consum
worsen your existing condition and cause stomach pain, sickness, headache,
flushing etc.

!### Kidney

Use with CautionOKAFLOX TZ 200/600MG TABLET should be taken with caution in patients with kidney
disease or conditions (such as difficulty urinating, kidney injury, kidney
failure, kidney transplant or undergoing dialysis management). Consult your
doctor before taking.

!### Liver

Use with CautionOKAFLOX TZ 200/600MG TABLET should be taken with caution in patients with liver
disease (such as hepatitis, jaundice, liver failure etc.). Consult your doctor
before taking.

!### Allergy

ContraindicatedDo not take OKAFLOX TZ 200/600MG TABLET or consult your doctor if you are
allergic to Ofloxacin and/or Satr
allergic to other quinolone antibiotics such as ciprofloxacin, norfloxacin etc.

!### Lungs

Use with CautionOKAFLOX TZ 200/600MG TABLET should be taken with caution in patients with lung
disease or conditions (such as having undergone lung transplant etc.). Consult
your doctor before taking.

!### Heart Disease

Use with CautionOKAFLOX TZ 200/600MG TABLET should be taken with caution in patients with heart
disease or conditions (such as irregular heartbeat, heart attack, poor
functioning of the heart, heart transplant etc.). Consult your doctor before
taking.

!### Use In Pediatrics

ContraindicatedOKAFLOX TZ 200/600MG TABLET is not recommended for use in children and
adolescents less than 18 years old. Consult your doctor before taking.

!### Use In Geriatrics

Use with CautionOKAFLOX TZ 200/600MG TABLET should be used with caution in the elderly. Consult
your doctor before taking.

Others

OKAFLOX TZ 200/600MG TABLET is not recommended for use if you:

• genetic disorders (such as Cockayne syndrome, G6PD deficiency)
• fits or seizures
• tendon muscle weakness or rupture
• pain in the nerve etc.

Before taking OKAFLOX TZ 200/600MG TABLET, inform your physician if you have:

• diabetes
• abnormal blood pressure
• low RBC or hemoglobin level (anemia)
• severe or recurrent dysentery/loose stools
• severe skin diseases such as steven- johnson syndrome, toxic epidermal necrolysis, Marfan syndrome or Ehlers-Danlos syndrome, Turner syndrome, Sjogren’s syndrome etc.)
• autoimmune diseases such as rheumatoid arthritis etc.
• muscle-weakening diseases such as myasthenia gravis, rhabdomyolysis
• inflammation of the digestive system
• abnormal body movements like fits/seizures
• imbalance of body fluids
• abnormal bleeding or clotting of blood
• fungal infection involving the vagina
• electrolyte or salt imbalance such as low potassium or magnesium
• G6PD deficiency
• psychiatric/mental disease, emotional imbalances
• plans to take a medical test such as blood or urine test

Interactions

A. Drug-Drug interactions:

Inform your physician, that if you are having,

• warfarin, acenocoumarin, phenprocoumon - used to manage or manage blood clot
• probenecid – used to manage gout
• methotrexate – used to manage diseases like cancer, psoriasis, rheumatoid arthritis etc.
• ibuprofen or diclofenac – used to relieve pain and fever
• cyclosporin – used to manage skin disease, rheumatoid arthritis and organ transplantation
• quinidine, hydroquinidine, disopyramide, amiodarone, sotalol, dofetilide, ibutilide, pentoxifylline – used to manage heart diseases
• insulin, glyburide/glibenclamide – used to manage diabetes
• phenytoin, phenobarbital, fosphenytoin - used to manage epilepsy/fits or seizures
• lithium – used to manage depression
• theophylline- used to manage wheezing, asthma etc.
• erythromycin, clarithromycin, azithromycin – used to manage the bacterial infection
• didanosine – used in the management of HIV infection
• tacrolimus -  used to manage eczema, dermatitis etc.
• sucralfate – used to manage stomach acidity or stomach ulcer
• cimetidine – used to manage stomach ulcers, gastritis, stomach acid reflux etc.
• ketoconazole – used to manage fungal infection
• disulfiram - used to manage alcoholism
• fluorouracil - used to manage cancers
• Oxytetracycline – used to manage tetanus, gangrene etc.
• medicine or supplements containing zinc, calcium, magnesium, aluminum or iron
• herbal medicines

B. Drug-Food interaction:

OKAFLOX TZ 200/600MG TABLET may interact with caffeine-containing products
(coffee, chocolates etc.), grapefruit juice and foods rich in calcium, dairy
products such as milk as well as butter, yogurt, cheese etc. Consult your doctor
for diet advice.

Overdosage:

If you or anyone else accidentally take too much of OKAFLOX TZ 200/600MG TABLET,
consult your doctor immediately or visit the nearby hospital if your experience
is persistent or worsening of any side effects.

Synopsis

Drug	:	Ofloxacin, Tinidazole
Pharmacological Category	:	Fluroquinolones and Nitroimidazoles
Therapeutic Indication	:	To manage bacterial and parasitic infection
Dosage Forms	:	Tablet, Syrup

More Information

• Keep out of reach from children
• Store at room temperature

FAQs About OKAFLOX TZ 200/600MG TABLET

Q: Can [GBBNKEYWORD] be used by pregnant women?

A: OKAFLOX TZ 200/600MG TABLET is not recommended for use in pregnant women.
However, consult your doctor for advice as your doctor may outweigh the risks
and benefits during life-threatening conditions.

Q: Can OKAFLOX TZ 200/600MG TABLET cause tendon weakness?

A: OKAFLOX TZ 200/600MG TABLET can increase the risk of tendon weakness or
rupture. Stop taking this medicine and/or consult your doctor immediately if you
experience symptoms like tendon pain in joints, swelling, hearing or feeling a
snap or pop in a tendon area, bruising right after an injury in a tendon area,
unable to move the affected area or bear weight etc.

Q: Can OKAFLOX TZ 200/600MG TABLET cause abnormal behavior?

A: OKAFLOX TZ 200/600MG TABLET is a combination of ofloxacin and tinidazole. The
side effect of ofloxacin includes changes in behavior, anxiety, nervousness,
nightmares, depression, emotional imbalance etc. Consult your doctor immediately
if the symptoms occur.

Q: Is OKAFLOX TZ 200/600MG TABLET safe for use in patients with heart
disease?

A: OKAFLOX TZ 200/600MG TABLET should be used with caution in patients with
heart disease such as heart attack, myocardial infarction, poor functioning of
the heart, abnormal heartbeat etc. Also, inform your doctor if you have
undergone a heart transplant. Consult your doctor before use.

Q: Can OKAFLOX TZ 200/600MG TABLET cause headache?

A: The most common side effects of taking OKAFLOX TZ 200/600MG TABLET may
include headache, changes in taste sensation (metallic/bitter), feeling sick,
weakness, stomach upset, vomiting, gaining weight, dizziness, difficulty in
sleeping, itching, diarrhea (loose stools) or constipation (hard stools) etc. If
you are experiencing a headache, take rest and get adequate sleep and stay
hydrated. Consult your doctor immediately if any of the symptoms persist or
worsen.

Useful Diagnostic Tests

• CBP
• LFT
• KFT
• Random blood glucose level
• Fasting blood glucose level
• HBA1c
• Oral glucose tolerance test
• Capillary blood glucose (home monitoring)
• TSH
• PT -INR
• BT/CT - test
• Urine test for blood sugar (glucose)
• Stool examination test
• USG abdomen
• MRI, CT scan
• Urinary analysis
• Culture sensitivity test