NEFROPRES C 100 Tablet 10's

Introduction About NEFROPRES C 100 TABLET

NEFROPRES C 100 TABLET contains Clonidine which belongs to group of medicines
called Antihypertensives. NEFROPRES C 100 TABLET is used to lower high blood
pressure to manage hypertension in affected individuals.

NEFROPRES C 100 TABLET is not recommended for use in patients allergic to
clonidine. It is also not recommended for use in patients with rare hereditary
condition of galactose intolerance, and/or heart diseases (such as heart
failure, slow/irregular heart rate).

Before taking NEFROPRES C 100 TABLET, inform your doctor if you have Raynaud’s
phenomenon (condition marked by decreased blood flow to the fingers and toes),
depression, constipation, altered sensation, diabetes, liver, and/or kidney
problems.

NEFROPRES C 100 TABLET is not recommended for use during pregnancy and in women
planning for pregnancy. It is also not recommended for use in breast-feeding
women.

NEFROPRES C 100 TABLET is not recommended for use in children and adolescents
(aged below 18 years) and is advised to be used with caution in elderly patients
(aged 60 years/above) after consulting the doctor.

The most common side effects of taking NEFROPRES C 100 TABLET are dizziness, dry
mouth, tiredness, headache, constipation, nausea, and vomiting. Consult your
doctor if any of the symptoms worsen.

Uses Of NEFROPRES C 100 TABLET

• Helps to lower high blood pressure in affected individuals

How NEFROPRES C 100 TABLET Works

NEFROPRES C 100 TABLET works by relaxing the blood vessels which makes the heart
to pump blood more efficiently around the body thus resulting in the lowered
blood pressure and thereby managing hypertension in affected individuals.

How to use NEFROPRES C 100 TABLET

Take NEFROPRES C 100 TABLET as advised by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine. Your doctor will
decide the correct dose and duration for you depending upon your age, body
weight and disease condition.

Side Effects Of NEFROPRES C 100 TABLET

Common

• dizziness
• signs of sedation such as feeling tired or relaxed more than usual
• signs of orthostatic hypertension such as feeling dizzy when you stand up suddenly
• dry mouth
• depression
• sleeping problems
• headache
• constipation
• nausea
• pain below the ear (from the salivary gland)
• vomiting
• erectile dysfunction
• weakness

Uncommon

• difficulty in understanding, hallucinations, nightmares
• altered sensation in hands and feet
• regular unusually slow heartbeat
• signs of Raynaud’s phenomenon (condition marked by decreased blood flow to the fingers and toes) such as cold fingers or toes
• itching, rash, urticaria (nettle rash)
• feeling of discomfort and fatigue
• blurred vision
• confusion
• irrational/abnormal thoughts
• irritability
• decreased sexual drive / impotence
• constipation
• dryness of the nose and eyes
• pain in the salivary glands
• larger breasts (than normal) in men
• thinning of hair

Rare

• hair loss
• signs of high blood sugar such as feeling thirsty, urinating frequently, feeling weak or tired.

Stop taking NEFROPRES C 100 TABLET and contact your doctor immediately if you
experience

• signs of pseudo-obstruction of the large bowel such as colicky pain, vomiting and constipation

How To Manage Side Effects

Dizziness:

If you feel dizzy, keep your eyes closed sit or lie down. Do not drive or
operate machinery. Consult your doctor if the symptom did not improve.

Headache:

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a
pain-relieving balm on the head if required. Do not consume alcohol. Consult
your doctor if the symptom did not improve.

Constipation:

Eat more fiber especially soluble fiber foods such as beans, oats, oat bran,
rice bran, barley. Try to keep yourself hydrated and avoid taking any medicine
on your own to manage the side effect. Consult your doctor if the symptom
persists or does not improve.

Nausea and vomiting:

Take NEFROPRES C 100 TABLET with or just after a meal. Stick to simple meals.
Avoid eating oil rich or spicy foods, sugary snacks and drinks. Avoid drinking
too much liquid along with your meals, drink slowly in between meals. Consult
your doctor if the condition worsens.

Warning & Precautions

!### Pregnancy

NEFROPRES C 100 TABLET is not recommended for use in pregnant women. Consult
your doctor before taking it.

!### Breastfeeding

NEFROPRES C 100 TABLET is not recommended for use in breast feeding women as it
may pass through milk. Consult your doctor before taking the medicine.

!### Driving and Using Machines

Do not drive or operate any machines if you feel drowsy, dizzy or have some
disturbances of vision after taking NEFROPRES C 100 TABLET.

!### Alcohol

Avoid consum
the effect of the medicine.

!### Kidney

NEFROPRES C 100 TABLET should be used with caution in patients with kidney
problems. Consult your doctor before taking it.

!### Liver

NEFROPRES C 100 TABLET should be used with caution in patients with liver
problems. Consult your doctor before taking the medicine.

!### Allergy

Do not take NEFROPRES C 100 TABLET if you are allergic to Clonidine, and/or any
of the other ingredients of this medicine.

!### Heart Disease

NEFROPRES C 100 TABLET is not recommended for use in patients with problems such
as heart failure, slow/irregular heart rate. Consult your doctor before taking
the medicine.

Others

NEFROPRES C 100 TABLET is not recommended for use if you:

• have rare hereditary condition of galactose intolerance

Before taking NEFROPRES C 100 TABLET, inform your doctor if you:

• have signs of Raynaud’s phenomenon (condition marked by decreased blood flow to the fingers and toes) such as cold fingers or toes
• have or ever had depression
• have constipation
• have altered sensation (nerve disorder that causes your hands and feet to feel different
• low blood pressure while standing up
• have intolerance or difficulty to digest certain sugars (such as lactose)
• have diabetes
• have signs of phaeochromocytoma (rare tumor of the adrenal gland) such as high blood pressure, headache, heavy sweating
• stroke or transient ischeamic attack (TIA)

Use in Pediatrics:

NEFROPRES C 100 TABLET is not recommended for use in children and adolescents
(aged below 18 years). Consult your doctor before takingthe medicine.

Use in Geriatrics:

NEFROPRES C 100 TABLET should be used with caution in elderly patients (aged
above 60 years). Consult your doctor before taking.

Interactions

A. Drug - Drug interactions:

Before taking NEFROPRES C 100 TABLET, inform your doctor if you are taking,

• other medicines that make you drowsy Ex. brompheniramine, diphenhydramine
• non-steroidal anti-inflammatory drugs (used to reduce fever & inflammation, and relieve pain) Ex. ibuprofen
• imipramine or mirtazapine (used to manage depression)
• antipsychotics (used for severe mental illness such as schizophrenia) Ex. chlorpromazine
• beta blockers (used to manage hypertension) Ex. atenolol
• water tablets – frusemide (diuretics)
• alpha blockers (used for prostate problems in men) Ex. prazosin or doxazosin
• vasodilators (medicines used to dilate or manage constriction of blood vessels to allow free blood flow to the organs) Ex. diazoxide or sodium nitroprusside
• calcium antagonists (used to manage hypertension) Ex. verapamil, diltiazem hydrochloride
• ACE inhibitors (used to manage hypertension) Ex. captopril, lisinopril
• digitalis glycoside (used to manage heart diseases) Ex. digoxin

Over dosage:

If you or anyone else accidentally take too much of NEFROPRES C 100 TABLET,
consult your doctor immediately or visit the nearby hospital. Symptoms of
overdose are slow heartbeat, drowsiness, temporary breathlessness, dizziness,
weakness, lethargy, feeling cold, vomiting, looking pale, irregular heartbeat,
and coma.

Synopsis

Drug	:	Clonidine
Pharmacological Category	:	Central alpha agonists
Therapeutic Indication	:	Hypertension (high blood pressure)
Dosage Forms	:	Tablet, Injection

More Information

• Keep NEFROPRES C 100 TABLET out of reach of children
• Store NEFROPRES C 100 TABLET below 30°C

FAQs About NEFROPRES C 100 TABLET

What dosage doesNEFROPRES C 100 TABLET be taken in a day?

Take NEFROPRES C 100 TABLET as advised by your physician. Do not crush or chew
the medicine. Swallow the medicine with glass of water. Your doctor will decide
the correct dose and duration for you depending upon your age, body weight and
disease condition.

CanNEFROPRES C 100 TABLET be taken if I have an intolerance to sugars?

It is advisable to consult your doctor before taking NEFROPRES C 100 TABLET if
you have intolerance to certain sugars (such as lactose). NEFROPRES C 100 TABLET
is generally not recommended for use if you have rare hereditary condition of
galactose intolerance (condition marked by inability of the body to absorb
glucose and galactose). Consult your doctor before taking the medicine.

Will I feel, dizzy after takingNEFROPRES C 100 TABLET?

Yes, you may feel dizzy after taking NEFROPRES C 100 TABLET because dizziness is
the most common side effect associated with the use of the medicine. If you feel
dizzy, keep your eyes closed sit or lie down. Do not drive or operate machinery.
Consult your doctor if the symptom did not improve.

Can NEFROPRES C 100 TABLET be used in pregnancy?

[GNBKEYWORD] is generally not recommended for use during pregnancy and in women
planning to get pregnant. Inform your doctor immediately if you become pregnant
while taking NEFROPRES C 100 TABLET. Consult your doctor before taking the
medicine.

What are the side effects of NEFROPRES C 100 TABLET?

The most common side effects of taking NEFROPRES C 100 TABLET are dizziness, dry
mouth, tiredness, headache, constipation, nausea, and vomiting. Consult your
doctor if any of the symptoms worsen.

Useful Diagnostic Tests

• Blood Pressure Test
• Ambulatory (24-hour) blood pressure monitoring