MIKANIP 100mg Injection 1's

Introduction About MIK

MIK
called Aminoglycoside Antibiotic. It is used in the management of serious
infections caused by the bacteria that are sensitive to amikacin such as
respiratory tract and lung infections, gastrointestinal infections, inflammation
of the inner lining of the heart, infected burns, or bacterial infections of the
blood.

Prior to or during the management with MIK
might ask you take some diagnostic tests to check your kidney function, hearing
and levels of MIK

MIK
gravis (severe weakness of body muscles). Before receiving MIK
INJECTION inform your doctor if you have kidney problems, hearing difficulty or
tinnitus (ringing or buzzing in the ears), an antibiotic-related hearing loss or
a mitochondrial mutation disease (a condition caused by variations in the
mitochondrial genome).

MIK
breast-feeding women only if considered necessary. Contact your doctor before
receiving it. Caution must be exercised while using MIK
premature or new-born infants.

MIK
the age of 60 years. Consult your doctor before receiving it. The most common
side effects of receiving MIK
ears), hearing problem, inner ear damage, decrease in excretion of urine.
Consult your doctor if the symptoms do not resolve or worsen.

Uses Of MIK

• it is used in the management of serious infections caused by the bacteria that are sensitive to amikacin

How MIK

MIK
functions of the bacteria. It interferes with the present bacteria and disrupts
the cell membrane along with hampering its various cellular function which leads
to bacterial death. It also stops the further spread of the infection this way.

How to use MIK

MIK
vein or muscle as an intramuscular or intravenous injection or as infusion
(drip). Your doctor will determine the correct dose and duration for you based
upon your body weight, age and severity of disease condition.

Side Effects Of MIK

Common

• tinnitus (ringing sensation in the ears)
• hearing problem, inner ear damage
• kidney function problems (nausea, vomiting, loss of appetite, changes in urination, sleep problems)
• decrease in excretion of urine

Uncommon

• infections caused by resistant yeast or bacteria
• nausea
• vomiting
• rash

Rare

• changes in level of blood cells such as reduced platelets and red blood cells, reduced or increased white blood cells (fatigue, weight loss, feeling of being unwell, paleness)
• low levels of magnesium in the blood (fatigues, muscle weakness or cramps, numbness)
• tremors
• sensory disturbances
• headache
• dizziness or vertigo (spinning feeling)
• balance disorders
• abnormal tingling or ‘pins and needles’ feeling
• blindness or other vision disturbances
• retinopathy (changes in the retina of your eye)
• low blood pressure
• phlebitis (inflammation of vein walls)
• itching, hives, joint pain
• muscle twitching
• fever
• liver function changes (dark urine, pale stool, fever, abdominal pain, jaundice)
• increase in heart rate
• heart muscle inflammation

Stop receiving MIK
experience any of the following side effects:

• persisting ringing in your ears
• decrease in the amount of urine you produce
• severe allergic reaction characterised by sudden itchy rash (hives), swelling of the feet, ankles, hands, face, lips, mouth or throat (which may cause difficulty in swallowing or breathing), feeling of faintness
• paralysis
• deafness or loss of hearing
• sudden loss of breathing
• severe kidney failure

How To Manage Side Effects

Nausea:

Stick to simple meals while receiving MIK
or spicy food. Do not take any medication by yourself. Ask for your doctor’s
advice if nausea doesn’t improve or worsens.

Vomiting:

Eat light, bland foods and avoid oily, deep fried or sweet foods. Avoid
carbonated drinks. Ask for your doctor’s advice if vomiting doesn’t improve or
worsens.

Headache:

Rest and relax. Consume plenty of electrolytes and water. If necessary, apply a
balm to the head to relieve the pain. Do not consume alcohol. Consult your
doctor if the headache did not improve.

Dizziness:

Try to rest and relax. Get enough sleep. If you feel dizzy, avoid from driving
or operating machinery. Avoid alcohol consum
Contact your doctor if dizziness worsens.

Rash:

Hot water may irritate your skin, so avoid taking hot showers. Do not scratch
the affected area. Contact your doctor if rash worsens.

Warning & Precautions

!### Pregnancy

MIK
considered necessary. Contact your doctor before receiving MIK
INJECTION.

!### Breastfeeding

MIK
if considered necessary as it is not known if it is excreted into breast milk.
Contact your doctor before receiving MIK

!### Driving and Using Machines

Do not drive or operate machines, if you feel dizzy after receiving MIK
100MG INJECTION.

!### Kidney

MIK
problems. Your doctor might monitor your kidney function. Consult your doctor
before receiving MIK

!### Allergy

Do not receive MIK
amikacin or any other aminoglycoside or allergic to sulphites or to other
ingredients of this medicine.

Others

MIK

• suffer from myasthenia gravis (severe weakness of body muscles)

Before receiving MIK

• have tinnitus or difficulty hearing (ringing or buzzing in the ears)
• or any member of your family suffers from an antibiotic-related hearing loss
• or any member of your family have mitochondrial mutation disease (a condition caused by variations in the mitochondrial genome, the components of your cells that help make energy)

Use in paediatrics:

MIK
infants. Ask your child’s doctor for advice.

Use in geriatrics:

MIK
doctor might adjust your dose depending on your kidney function. Consult your
doctor before receiving MIK

Interactions

A. Drug-Drug interactions:

Before receiving MIK
any of the following medicines:

• diuretics (water tablets) such as furosemide and ethacrynic acid (used to get rid of fluid build-up in the body)
• indomethacin (used to reduce inflammation)
• other antibiotics such as penicillin, cephalosporins, gentamycin, tobramycin (used to manage certain infections)
• bisphosphonates such as alendronate (medicine used to manage bone mass loss)
• vitamin B1 (thiamine) (medicine used to metabolize carbohydrates, proteins, and fats)
• platinum compounds (metals used in chemotherapy) such as cisplatin, carboplatin, oxaliplatin
• muscle relaxants such as atracurium, rocuronium, vecuronium (used to relax muscles)
• anaesthetics such as methoxyflurane (used before surgery)

Overdosage:

MIK
in a hospital, and so it is unlikely to receive an overdose. However, inform
your doctor immediately if you experience any unusual symptoms.

Synopsis

Drug	:	Amikacin
Pharmacological Category	:	Aminoglycoside Antibiotics
Therapeutic Indication	:	Serious bacterial infections
Dosage Forms	:	Eye drops, Injection, Infusion

More Information

• Keep MIK
• Store MIK

FAQs About MIK

What is MIK

MIK
called Aminoglycoside Antibiotic. It is used in the management of serious
infections caused by the bacteria that are sensitive to amikacin

How much time does it take to administer MIK

MIK
vein or muscle as an intramuscular or intravenous injection or as infusion
(drip). If given as an infusion, it may take from 30-60 minutes and 1-2 hours
for infants. Your doctor will determine the correct dose and duration of MIK
100MG INJECTION for you based upon your body weight, age and severity of disease
condition.

Is it safe to use MIK

MIK
infants and kidney function should be monitored. Consult your doctor before
receiving MIK

Can I receive MIK

MIK
necessary as it is not known whether MIK
breast milk. Contact your doctor before receiving MIK

Do I need to undergo any tests prior to, or while being managed with MIK
100MG INJECTION?

Prior to or during the management with MIK
might ask you take some diagnostic tests to check your kidney function, hearing
and levels of MIK
sure that you are well hydrated.

Useful Diagnostic Tests

• Complete blood count
• Peripheral Smear Examination
• Kidney Function Test
• Hearing Function Test