MIBETA SR 40 Tablet 15's

Introduction About MIBETA SR 40 TABLET

MIBETA SR 40 TABLET is used to manage hypertension (high blood pressure), angina
(chest pain) and arrhythmia (irregular heart rhythm).

It can also be used to control abnormal increase in blood pressure and/or heart
rate caused due to various underlying conditions such as anxiety, overactive
thyroid gland, phaeochromocytoma (tumours of adrenal gland) or Hypertrophic
Subaortic Stenosis (thickening of heart muscles).

It contains Propranolol which belongs to the group of medicines called Beta
blockers.

It can also be used to manage heart attacks and migraine headaches. It also
controls shakiness of the body by blocking abnormal nerve signals between the
brain and the muscles.

Before taking MIBETA SR 40 TABLET inform your doctor if you have any liver or
kidney problems. You must also inform your doctor if you have any other types of
anginas (unstable or Prinzmetal angina) or arrhythmia (such as
Wolf-Parkinson-White Syndrome), any breathing problems, or diabetes as a
precaution.

MIBETA SR 40 TABLET is not recommended for use in patients with severe asthma,
hypotension (low blood pressure) or shock. It is also not suitable for use in
patients with heart block, history of heart attack or heart failure.

Do not take MIBETA SR 40 TABLET without consulting your doctor if you are
pregnant or breastfeeding. The most common side effects of taking MIBETA SR 40
TABLET are cold fingers and toes, slow heartbeat, tiredness, sleep disturbances
and Raynaud’s syndrome (numbness and spasm in the fingers followed by warmth and
pain). Consult your doctor if any of these side effect troubles you.

Uses Of MIBETA SR 40 TABLET

• hypertension (high blood pressure)
• angina pectoris (chest pain)
• arrhythmia (irregular heart rhythm)
• migraine (severe headache on side of the head)
• Reduce tremor (shakiness) and anxiety
• Signs and symptoms of overactive thyroid gland (such as palpitation, nervousness, tremor, fixed stare, severe myopathy and sweating)
• phaeochromocytoma (signs include high blood pressure and fast heart rate caused due to tumour of adrenal glands)
• Hypertrophic Subaortic Stenosis (signs include thickening of heart muscles causing strain on heart while pumping blood)

Benefits of MIBETA SR 40 TABLET in Hypertension:

This medication works by reducing the workload on the heart and relaxing blood
vessels, resulting in improved blood flow and lower blood pressure levels.

Benefits of MIBETA SR 40 TABLET in Angina pectoris:

It reduces chest pain episodes, improves exercise tolerance by minimizing the
heart’s exertion, allowing individuals to perform daily activities with reduced
discomfort. It also helps manage stress-induced angina by mitigating the
physical effects of stress and anxiety on the heart, providing comprehensive
protection for patients with this condition.

Benefits of MIBETA SR 40 TABLET in arrhythmia:

It helps stabilize the heart by slowing electrical signals in the heart muscle.
This action restores a regular rhythm, preventing episodes of rapid or irregular
heartbeats.

Benefits of MIBETA SR 40 TABLET in migraine:

It helps in preventing migraines by stabilizing blood vessels, modulating nerve
activity and blood flow in the brain and reducing the triggers that cause
migraine episodes. Many users report a noticeable decline in the frequency and
severity of migraines over time.

Benefits of MIBETA SR 40 TABLET in tremor and anxiety:

It works by blocking adrenaline’s effect on the body, which calms the overactive
signals causing tremors. It is particularly effective in controlling physical
symptoms of anxiety, such as a racing heart, sweating, and trembling. By calming
the heart rate, it helps individuals feel more at ease in stressful situations.
Blocks the body’s adrenaline response, it allows users to remain calm and
confident during high-pressure scenarios.

How MIBETA SR 40 TABLET Works

MIBETA SR 40 TABLET is a beta-blocker. It works by blocking the actions of
certain chemical messengers (such as adrenaline and noradrenaline) in our body
that controls the function of the heart, brain and kidneys and lungs.

In the heart, stopping the actions of these chemical messengers reduces the
heart rate and force of contraction. This helps to control abnormal heart rate
in patients suffering from arrhythmia.

It can also reduce the risk of abnormal heart signs (such as racing heartbeat,
nervousness and high blood pressure) associated with phaeochromocytoma or
anxiety.

MIBETA SR 40 TABLET can relax the blood vessels supplying the heart and the
brain. This action improves blood flow and oxygen supply to the heart and makes
the heart to pump blood more efficiently with less pressure. It also helps in
managing and managing problems caused due to poor blood circulation such as
chest pain (angina), heart attack or migraine.

Additionally, MIBETA SR 40 TABLET reduces the production of thyroid hormones
(triiodothyronine) in patients suffering from overactive thyroid gland. It also
stops the transfer of abnormal nerve signals between the brain and the muscles
which helps in reducing tremors.

How to use MIBETA SR 40 TABLET

Take MIBETA SR 40 TABLET as directed by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine.

Dosage and Administration

• Follow Prescribed Dosage- it varies based on the medical condition and individual response.
• Always follow your doctor’s prescri
• Common starting doses include:

Hypertension: 40mg twice daily.

Migraine Prevention: 40mg two to three times daily.

Anxiety: 40mg taken as needed (30-60 minutes before a stressful situation).

Arrhythmias: 10-40mg three to four times daily.

• It is best taken on an empty stomach or before meals for better absor

Missed Dosage instructions for MIBETA SR 40 TABLET:

• If you miss a dose of MIBETA SR 40 TABLET take it as soon as you remember. If it is almost time for your next dose, skip the missed dose.
• Do not double the dose to make up for the missed one.
• Consistency is essential, especially for chronic conditions like hypertension and arrhythmias. Setting reminders can help ensure timely doses.

Overdosage of MIBETA SR 40 TABLET:

• Taking more than the prescribed dose of MIBETA SR 40 TABLET can lead to serious complications, including extremely slow heart rate (bradycardia), difficulty breathing, low blood pressure (hypotension), seizures or loss of consciousness.
• What to Do in Case of Overdose: Immediately seek medical attention or contact a poison control center. Symptoms of overdose require urgent intervention, which may include supportive measures like activated charcoal or IV fluids.

Side Effects Of MIBETA SR 40 TABLET

Like all medicines, MIBETA SR 40 TABLET may cause certain side effects, although
not everybody gets them.

The most common side effects of taking MIBETA SR 40 TABLET are:

• fingers and toes may become cold
• slow heartbeat
• signs of Raynaud’s syndrome (numbness and spasm in the fingers followed by warmth and pain)
• sleep disturbances, nightmares
• fatigue (tiredness)

When to consult your doctor?

• signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth, or throat which can lead to difficulty in breathing or swallowing)
• slow heart rate and low blood pressure causing dizziness, light-headedness, fainting or blurred vision
• worsening of existing condition

How To Manage Side Effects

!### Sleep Disturbances

Practicing good sleep practices such as having a regular bedtime schedule,
avoiding naps in the daytime, limiting caffeine and TV before bedtime can help
you to sleep peacefully. If the symptom does not improve, consult your doctor.

!### Tiredness

Include whole grains, lean proteins, and fresh fruits and vegetables in your
meals. These foods help maintain steady energy levels throughout the day. Stay
hydrated, avoid heavy or processed foods. Get enough sleep, incorporate light
exercise, limit alcohol and stimulants like caffeine

Warning & Precautions

!### Pregnancy

Monitoring requiredMIBETA SR 40 TABLET is generally not recommended for use in pregnant women
unless considered necessary by the physician, as it may harm the growing baby.
Studies in
fetal weight and delayed ossification, at high doses of propranolol. Therefore,
inform your doctor before taking MIBETA SR 40 TABLET if you are pregnant, think
you might be pregnant or planning to have a baby.

!### Breastfeeding

Use with CautionMIBETA SR 40 TABLET may excrete in breast milk. Limited
specifically on the excretion of propranolol in milk, but beta-blockers as a
class are known to pass into milk. Therefore, it should be used with caution in
breastfeeding women. Consult your doctor for advice before taking it.

!### Driving and Using Machines

SafeMIBETA SR 40 TABLET is unlikely to affect your ability for driving or handling
any heavy tools or machines. However, if your experience any dizziness or
drowsiness, do not drive or handle any heavy tools or machines as a precaution.

!### Alcohol

Consult your doctorAvoid consum
you feel dizzier and drowsier.

!### Kidney

Use with CautionMIBETA SR 40 TABLET should be used with caution in patients with kidney
problems. Therefore, consult your doctor before taking it.

!### Liver

Use with CautionMIBETA SR 40 TABLET should be used with caution in patients with liver problems.
Therefore, consult your doctor before taking it.

!### Allergy

ContraindicatedDo not take MIBETA SR 40 TABLET if you are allergic to propranolol.

!### Lungs

Consult your doctorMIBETA SR 40 TABLET is not recommended for use in patients suffering from
asthma. It should be used with caution in patients with other respiratory
problems (such as chronic bronchitis, emphysema, COPD or bronchospasm).
Therefore, consult your doctor before taking it.

!### Heart Disease

Consult your doctorMIBETA SR 40 TABLET is not recommended for use in patients with sinus
bradycardia (slow heart beat due to problems in SA nodes), heart block,
congestive heart failure or heart defects. It should be used with caution in
patients with a previous history of heart failure or other heart problems.
Therefore, consult your doctor before taking it.

!### Use In Pediatrics

Consult your doctorThe safety and effectiveness of MIBETA SR 40 TABLET have not been established in
children and adolescents (aged below 18 years). Therefore, it should be used in
children only if prescribed by the physician.

!### Use In Geriatrics

Use with CautionMIBETA SR 40 TABLET should be used with caution in elderly patients (aged above
65 years).
older populations due to age-related changes in cardiovascular physiology and
drug metabolism. Therefore, consult your doctor before taking it.

Others

MIBETA SR 40 TABLET is not recommended for use if you:

• have cardiogenic shock (heart cannot pump blood suddenly)
• have hypertensive emergency crisis (abnormal increase in blood pressure which is severe)
• have very low blood pressure
• have can increased acidity of the blood (metabolic acidosis)
• are on a strict fasting diet
• suffer from other forms of angina (Prinzmetal’s angina)

Before taking MIBETA SR 40 TABLET, inform your doctor if you:

• have diabetes
• suffer from unstable angina (chest pain that occurs in the absence of any stressful activity)
• are going for glaucoma screening test
• have muscle weakness (myasthenia gravis)
• are planning for any major surgery
• have other types of arrhythmias (such as Wolf-Parkinson-White Syndrome)
• have any bleeding problems
• have stroke or any circulatory problems
• have swollen ankles

Safety Advice

Expert advice to follow while taking MIBETA SR 40 TABLET:

• Take as prescribed and at the same time daily.
• Monitor blood pressure and heart rate regularly.
• Avoid sudden discontinuation of the medication.
• Be mindful of alcohol, smoking, and other medications.
• Protect yourself in cold weather.
• Inform your doctor about any side effects or new medications.
• Use caution during pregnancy and breastfeeding.
• Monitor blood glucose levels if diabetic.
• Visit your healthcare provider regularly for check-ups.

Interactions

A. Drug - Drug interactions:1. Calcium Channel Blockers (e.g., Verapamil, Diltiazem)

Both calcium channel blockers and beta-blockers like Inderal reduce heart rate
and blood pressure. When taken together, they can cause excessive bradycardia
(slow heart rate) and hypotension (low blood pressure).

2. Clonidine (Alpha-2 Agonist)

Clonidine can synergistically lower blood pressure. However, abrupt
discontinuation of clonidine while on propranolol can cause a rebound
hypertensive crisis.

3.Antiarrhythmic Drugs (e.g., Amiodarone, Sotalol)

Combining antiarrhythmic drugs can increase the risk of heart block and severe
bradycardia, particularly in patients with pre-existing heart conditions.

4.Antidepressants (e.g., Fluoxetine, Paroxetine)

Some selective serotonin reuptake inhibitors (SSRIs) may increase the plasma
concentration of propranolol, potentially leading to an enhanced beta-blocking
effect and increased risk of bradycardia.

5. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) (e.g., Ibuprofen, Naproxen)

NSAIDs may reduce the effectiveness of Inderal in controlling blood pressure by
inhibiting the production of prostaglandins, which help regulate kidney
function.

6.Insulin and Oral Hypoglycemics

Beta-blockers like propranolol can mask the symptoms of hypoglycemia (low blood
sugar), making it harder to recognize low blood sugar levels, especially in
diabetics.

7.Monoamine Oxidase Inhibitors (MAOIs) (e.g., Phenelzine, Tranylcypromine)

The combination of MAOIs and Inderal can lead to a hypertensive crisis due
to excessive catecholamine release.

8.Ergot Alkaloids (e.g., Ergotamine)

Ergotamine, often used to treat migraines, can cause vasoconstriction, and when
combined with propranolol, it may further increase the risk of severe
hypertension or poor circulation.

Refer the drug-drug interactions of propranolol,

Synopsis

Drug	:	Propranolol
Pharmacological Category	:	Beta blockers
Therapeutic Indication	:	Hypertension, angina pectoris, atrial fibrillation, migraine, tremor and anxiety, thyrotoxicosis, phaeochromocytoma
Dosage Forms	:	Tablet, Capsule, Injection

More Information

1. Onset of Action: After taking a 40mg tablet of propranolol by mouth, the drug typically begins to take effect within 30 to 60 minutes. The maximum concentration of propranolol in the blood is usually reached around 1 to 2 hours after oral ingestion. At this point, the therapeutic effects are most pronounced, such as a reduction in heart rate, blood pressure, and anxiety symptoms.
2. Duration of Action: The effects of propranolol can last approximately 3 to 6 hours after a single dose. Propranolol also comes in extended-release formulations (such as Inderal LA), which can provide prolonged action, lasting up to 24 hours.

FAQs About MIBETA SR 40 TABLET

Q: Can MIBETA SR 40 TABLET used in asthmatic patients?

A: No, MIBETA SR 40 TABLET cannot be used in patients suffering from asthma.
This is because using it can cause breathing problems, which may trigger an
asthma attack. Always inform your doctor if you have or ever had asthma or any
kind of difficulty breathing difficulty, before starting management with MIBETA
SR 40 TABLET.

Q: Does MIBETA SR 40 TABLET make you feel sleepy?

A: MIBETA SR 40 TABLET can occasionally cause dizziness or tiredness while
taking it. Don't drive, use machinery, or perform any activities that require
alertness. If this occurs to you, consult your doctor for opinion.

Q: Should we take MIBETA SR 40 TABLET before or after food?

A: MIBETA SR 40 TABLET should preferably be taken before meals. It should be
swallowed with a drink of water.

Q: When can I expect relief in my symptoms after taking MIBETA SR 40 TABLET?

A: MIBETA SR 40 TABLET usually starts working within a few hours of taking it.
However, to notice considerable changes in the symptoms of high blood pressure
or heart conditions, it may take a week. You will not be able to notice any
difference, but that does not mean it is not working. However, keep taking
MIBETA SR 40 TABLET as prescribed by your doctor to get its full benefits.

Q: What are the uses of MIBETA SR 40 TABLET?

A: MIBETA SR 40 TABLET It is used to manage hypertension, angina and arrhythmia.
It can also be used to manage signs and symptoms associated with anxiety,
overactive thyroid gland, phaeochromocytoma or Hypertrophic Subaortic Stenosis.
It can manage heart attacks and migraine headaches and reduce tremors.

Q: What type of a medicine is MIBETA SR 40 TABLET?

A: MIBETA SR 40 TABLET is a beta-blocker. It works by blocking the actions of
certain chemical messengers (such as adrenaline and noradrenaline) in our body
that controls the function of the heart, brain and kidneys and lungs. This helps
in normalizing heart functions, migraine, anxiety and tremors. It also reduces
heart signs associated with anxiety, overactive thyroid gland, phaeochromocytoma
or Hypertrophic Subaortic Stenosis

Q: Can MIBETA SR 40 TABLET reduce anxiety?

A: Yes. MIBETA SR 40 TABLET helps to control racing heartbeat and nervousness
associated with anxiety.

Q: What happens when I stop taking MIBETA SR 40 TABLET?

A: Do not stop taking MIBETA SR 40 TABLET without consulting your doctor as your
symptoms may re-appear once again. Make sure to take MIBETA SR 40 TABLET for the
stipulated duration recommended by your doctor to achieve maximum results.

Q: What is the best time to take MIBETA SR 40 TABLET?

A: MIBETA SR 40 TABLET is preferably taken before meals. Your doctor will decide
the best time for you to take MIBETA SR 40 TABLET based on your age, body weight
and disease condition.

Q: What to do if I forgot to take a dose of MIBETA SR 40 TABLET?

A: If you forgot to take a dose of MIBETA SR 40 TABLET, take it as soon as you
remember. However, if it is time for the next dose of MIBETA SR 40 TABLET, skip
the missed dose and take the next one regularly. Do not take a double dose of
MIBETA SR 40 TABLET to compensate the missed ones.

Q: What precautions should be followed while taking MIBETA SR 40 TABLET?

A: Before taking MIBETA SR 40 TABLET inform your doctor if you have any liver or
kidney problems. You must also inform your doctor if you have any other types of
anginas or arrhythmia, any breathing problems, diabetes, asthma, heart failure
as a precaution. Do not take MIBETA SR 40 TABLET without consulting your doctor
if you are pregnant or breastfeeding. Regularly visit your doctor and take all
the necessary blood test recommended by your doctor without fail.

Q: Can I consume alcohol while taking MIBETA SR 40 TABLET?

A: Avoid consum
make you feel dizzier and drowsier.

Q: What happens if I accidentally take more MIBETA SR 40 TABLET?

A: If you or anyone else accidentally took more MIBETA SR 40 TABLET, consult
your doctor immediately or visit the nearby hospital. Symptoms of overdose might
include slow heartbeat, low blood pressure, breathing difficulties with symptoms
such as fatigue, hallucinations, tremors, confusion, nausea, vomiting, body
spasms and fainting.

Q: Can I take MIBETA SR 40 TABLET daily?

A: Take MIBETA SR 40 TABLET as advised by your physician. Your doctor will
evaluate your health condition and suggests whether can you take MIBETA SR 40
TABLET every day or not.

Q: Is MIBETA SR 40 TABLET safe to use in diabetic patients?

A: MIBETA SR 40 TABLET may alter the blood sugar levels in your body. Therefore,
it is necessary to inform your doctor if you have diabetes before taking MIBETA
SR 40 TABLET as a precaution. Your doctor will closely monitor you blood sugar
levels to avoid the risk of side effects.

Q: What are the side effects of MIBETA SR 40 TABLET?

A: The most common side effects of taking MIBETA SR 40 TABLET are cold fingers
and toes, slow heartbeat, tiredness, sleep disturbances and Raynaud’s syndrome
(numbness and spasm in the fingers followed by warmth and pain). Consult your
doctor if any of these side effect troubles you.

Q: Can I stop taking MIBETA SR 40 TABLET once my symptoms subside?

A: No. Do not stop taking MIBETA SR 40 TABLET without consulting your doctor as
it may make your symptoms reappear. Therefore, take MIBETA SR 40 TABLET as
advised by your doctor for the stipulated duration.

Q: Can MIBETA SR 40 TABLET be taken during pregnancy?

A: MIBETA SR 40 TABLET is generally not recommended for use in pregnant women
unless considered necessary by the physician, as it may harm the growing baby.
Therefore, inform your doctor before taking MIBETA SR 40 TABLET if you are
pregnant, think you might be pregnant or planning to have a baby.

Q: Is MIBETA SR 40 TABLET safe to use in kidney disease?

A: MIBETA SR 40 TABLET should be used with caution in patients with kidney
problems. Your doctor will access your health condition and suggest a suitable
dose for you.

Q: Can the use of MIBETA SR 40 TABLET affect the liver?

A: Yes. MIBETA SR 40 TABLET may affect the way your liver work. It can elevate
the levels of certain liver enzymes in your body. Therefore, it should be used
with caution in patients with liver problems. Consult your doctor before taking
it.

Useful Diagnostic Tests

• Cardiac Risk Profile
• Lipid Profile
• Kidney Function Test