Mexaflo 400mg Tablet 10'S

Introduction About MEXAFLO 400MG TABLET

MEXAFLO 400MG TABLET contains Ofloxacin, which belongs to the group of medicines
called Antibiotics. It is used to manage various bacterial infections involving
the respiratory system, urinary system (kidneys and bladder), both male and
female genital organs (such as gonorrhoea), ears, nose, skin and soft tissues.
Bacterial infections are generally characterized by fever, extreme tiredness,
swollen lymph nodes in the neck, armpits, groin or elsewhere, headache,
nausea or vomiting.

Avoid consum
you feel dizzy or sleepy. Before recommending MEXAFLO 400MG TABLET your doctor
may advise you to take relevant tests to understand your condition.

MEXAFLO 400MG TABLET is not recommended for use if you have fits or ever had
swollen tendons. Before taking MEXAFLO 400MG TABLET, inform your doctor if you
have liver, kidney, heart, mental health problems, myasthenia gravis or
diabetes. MEXAFLO 400MG TABLET is not recommended for use by pregnant and
breastfeeding women, children or adolescents (less than 18 years old). Consult
your doctor before taking MEXAFLO 400MG TABLET.

The most common side effects of taking MEXAFLO 400MG TABLET are sleep problems,
headache, dizziness, nausea, vomiting, diarrhoea, itching, external genital
itching (women), vaginal inflammation and taste changes. Contact your doctor if
any of your symptoms get worse or persist.

Uses Of MEXAFLO 400MG TABLET

• Manage and manages bacterial infection in adults

How MEXAFLO 400MG TABLET Works

MEXAFLO 400MG TABLET works by binding to and inhibiting bacterial enzymes
required in DNA synthesis, thus interru
bacterial cell multiplication.

How to use MEXAFLO 400MG TABLET

Take MEXAFLO 400MG TABLET as advised by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine. Your doctor will
decide the correct dose and duration for you depending upon your age, body
weight and disease condition. Do not stop taking MEXAFLO 400MG TABLET unless
your doctor advises you to stop.

Side Effects Of MEXAFLO 400MG TABLET

Common

• sleep problems
• headache, dizziness
• nausea, vomiting, diarrhoea
• itching
• external genital itching (women)
• vaginal inflammation
• taste changes

Uncommon

• stomach pains
• irritated or burning eyes
• spinning sensations
• agitation, restlessness
• cough, sore nose or throat
• fungal infection
• skin rash or itching

Rare

• loss of appetite
• fast heartbeat
• drowsiness
• confusion, anxiety, nightmares, seeing, feeling or hearing things that are not there, mental illness
• changed or loss of smell
• altered liver enzymes or bilirubin levels
• too much sweating, hot flushes
• changes in kidney function tests
• low blood pressure (light-headedness, dizziness)
• hives, rash with pimples

Stop taking MEXAFLO 400MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• management resistance (no response to management)
• allergic reaction (severe rash, sudden wheezing, trouble swallowing or breathing, swelling of your lips, face, throat or tongue)
• watery diarrhoea, probably with blood in it, with stomach cramps and fever
• swollen tendons with pain, tenderness and sometimes restricted movement like in the Achilles tendon
• nerve damage (pain, burning, numbness, tingling or weakness in the hands and feet, touch sensitivity)
• blurred, double or changed colour vision
• anaemia (tiredness, dizziness, breathless when exercising, pale skin)
• drop in numbers of different types of blood cells (fever, chills, sore throat, ulcers in the mouth and throat)
• erythema multiforme (skin rash, which may blister, looks like dark spots surrounded by a lighter area or surrounded with a dark ring)
• toxic epidermal necrolysis (a widespread rash with blisters and skin peeling on most of the body surface)
• narrowing, blockage or leakage of blood vessels, sometimes leading to severe skin reactions and death of skin areas
• severe kidney problems (rash, fever, general aches and pains, bloody urine)
• hearing problems or loss
• liver problems like hepatitis or blockage in the bile duct (yellow eyes or skin, nausea, vomiting, loss of appetite, feeling generally unwell, fever, itching, pale faeces, dark urine, tender stomach)
• prolongation of QT interval (abnormal, fast, irregular or abnormal heart rhythm)
• depression with thoughts of harming or killing self
• Stevens-Johnson syndrome (a widespread rash with blisters and peeling skin, specifically around the mouth, nose, eyes and genitals)
• swelling of the lungs (coughing, trouble breathing, wheezing)
• rhabdomyolysis (temporary paralysis or weakness of the muscles, with pain and tenderness
• porphyria attack in patients with porphyria (a rare blood pigment disorder)
• muscle or ligament breakdown
• inflamed pancreas (severe pain in the stomach and back)
• loss of consciousness due to a severe drop in blood sugar levels
• uveitis (inflammation of the eye)
• exfoliative dermatitis (skin redness with too much scaling)
• aortic aneurysm and dissection (sudden, severe pain in your stomach, chest or back)
• fits

How To Manage Side Effects

Nausea:

Take MEXAFLO 400MG TABLET with or just after meals. Stick to simple meals. Avoid
eating oily or spicy foods. If your symptom gets worse or persist, consult your
doctor immediately.

Vomiting:

Get adequate rest. Drink lots of fluids, especially water. Have small sips if
you feel sick. Eat when you feel like it – you do not need to eat or avoid any
specific foods. Do not take medicines on your own to manage vomiting without
consulting your doctor. If your symptom gets worse or persist, consult your
doctor immediately.

Headache:

Drink an ample amount of water. Get adequate rest. Try to be relaxed and
stress-free. Do not take medicines on your own to manage a headache without
consulting your doctor. If your symptom gets worse or persist, consult your
doctor immediately.

Dizziness:

Lie down until the dizziness subsides, then get up slowly. Move slowly and
carefully, do not hurry. Get adequate rest. Drink plenty of water and other
fluids. Avoid coffee, cigarettes, alcohol and drugs. If your symptom gets worse
or persist, consult your doctor immediately.

Diarrhoea:

Drink lots of fluids, like water or fruit juice to keep yourself hydrated. Do
not take medicines on your own to manage diarrhoea without consulting your
doctor.  If your symptom gets worse or persist, consult your doctor immediately.

Skin itching:

Avoid hot showers because hot water can irritate your skin further. Do not
scratch the affected area. Use protective clothing when going outdoors.
Regularly moisturize your skin. If your symptom gets worse or persist, consult
your doctor immediately.

Warning & Precautions

!### Pregnancy

MEXAFLO 400MG TABLET is not recommended for use by pregnant women. Consult your
doctor before taking it.

!### Breastfeeding

MEXAFLO 400MG TABLET is not recommended for use by breastfeeding women. Consult
your doctor before taking it.

!### Driving and Using Machines

Do not drive or operate any machines if you experience sleepiness, dizziness or
problems with your eyesight after taking MEXAFLO 400MG TABLET.

!### Alcohol

Avoid consum
you feel dizzy or sleepy.

!### Kidney

MEXAFLO 400MG TABLET should be taken with caution in patients with kidney
disease. Consult your doctor before taking it.

!### Liver

MEXAFLO 400MG TABLET should be taken with caution in patients with liver
disease. Consult your doctor before taking it.

!### Allergy

Do not take MEXAFLO 400MG TABLET if you are allergic to Ofloxacin or any other
ingredients in this medicine or previously had an allergic reaction to any
quinolone antibiotic.

Heart Disease

MEXAFLO 400MG TABLET should be used with caution in patients with heart disease
or problems with a heartbeat, aortic aneurism (an enlarged or bulged large blood
vessel), aortic dissection (tear in the aortic wall) or family history of it,
vascular Ehlers-Danlos syndrome, vascular disorders like Takayasu arteritis,
giant cell arteritis, Behcet’s disease, high blood pressure, atherosclerosis,
endocarditis, prolonged QT interval, very slow heart rhythm, a weak heart or a
history of a heart attack. Consult your doctor before taking MEXAFLO 400MG
TABLET.

Others

MEXAFLO 400MG TABLET is not recommended for use if you:

• have or are at risk of fits
• ever had swelling of the tendons which can affect the wrist or the Achilles tendon
• have glucose-6-dehydrogenase deficiency (a problem with your red blood cells) or with a family history of glucose-6-dehydrogenase deficiency

Before taking MEXAFLO 400MG TABLET, inform your doctor if you:

• have connective tissue problems like Marfan syndrome
• have Turner syndrome (a genetic disorder)
• have Sjogren’s syndrome (an autoimmune disease)
• have myasthenia gravis (muscle weakness and excessive muscle fatigue)
• have diabetes (high blood sugar)
• have a salt imbalance (low blood potassium or magnesium levels)
• have or ever had any mental health problems

Use in pediatrics:

MEXAFLO 400MG TABLET is not recommended for use by children and adolescents
(under 18 years of age). Consult your doctor before taking it.

Use in geriatrics:

MEXAFLO 400MG TABLET should be used with caution by elderly patients. Consult
your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking MEXAFLO 400MG TABLET, inform your doctor if you are taking any of
the following medicines:

• medicines used to manage irregular heartbeat (Ex. disopyramide, amiodarone, sotalol quinidine, hydroquinidine, dofetilide, ibutilide, procainamide)
• other medicines used to manage bacterial infections (Ex. erythromycin, clarithromycin, azithromycin)
• medicines used to manage depression (Ex. amitriptyline, clomipramine, imipramine)
• medicines used to manage psychiatric disorders (Ex. risperidone, quetiapine)
• medicines containing iron or zinc
• sucralfate (used to manage stomach ulcers)
• medicines used to manage indigestion (Ex. magnesium carbonate, aluminium hydroxide)
• medicines used to manage inflammation (Ex. hydrocortisone, prednisolone)
• medicines used to relieve pain and inflammation (Ex. ibuprofen, diclofenac)
• theophylline (used to manage breathing problems)
• methotrexate (used to manage rheumatism)
• glibenclamide (used to manage diabetes)
• probenecid (used to manage gout)
• cimetidine (used to manage stomach ulcers or acidity)
• medicines used to manage blood clotting (Ex. warfarin, heparin)
• didanosine (used to manage HIV)
• furosemide (used to manage water retention)

Overdosage:

If you or anyone else accidentally take too much of MEXAFLO 400MG TABLET,
consult your doctor immediately or visit the nearby hospital. Symptoms of
overdose are confusion, dizziness, loss of consciousness, fit and nausea.

Synopsis

Drug	:	Ofloxacin
Pharmacological Category	:	Quinolone antibiotics
Therapeutic Indication	:	Manages and manages bacterial infection
Dosage Forms	:	Tablet, Solution, Eye ointment, Eye/Ear drops, Injection, Infusion, Syrup, Suspension, Cream

More Information

• Keep MEXAFLO 400MG TABLET out of reach from children
• Store below 30°C

FAQs About MEXAFLO 400MG TABLET

Does MEXAFLO 400MG TABLET manage urinary tract infections?

Yes. MEXAFLO 400MG TABLET is used to manage urinary tract infections. Your
doctor will decide the correct dose and duration for you depending upon your
age, body weight and disease condition.

Does MEXAFLO 400MG TABLET make you feel sleepy?

Yes. Avoid consum
management with MEXAFLO 400MG TABLET as it can make you feel dizzy or sleepy.

Can MEXAFLO 400MG TABLET manage typhoid?

According to some studies, MEXAFLO 400MG TABLET can be used to manage typhoid in
adults who are infected with S. typhi resistant to other medicines like
chloramphenicol, ampicillin and cotrimoxazole. However, consult your doctor
before taking MEXAFLO 400MG TABLET.

Can MEXAFLO 400MG TABLET make me feel suicidal?

MEXAFLO 400MG TABLET might come with a risk of suicidal thoughts or actions. If
at any time you have this kind of thought, immediately contact your doctor or go
to the nearby hospital.

Can MEXAFLO 400MG TABLET cause itching?

Yes. MEXAFLO 400MG TABLET may cause itching along with rashes. In such cases,
avoid hot showers because hot water can irritate your skin further. Do not
scratch the affected area. Use protective clothing when going outdoors.
Regularly moisturize your skin. Consult your doctor if your symptom does not
improve.

Can MEXAFLO 400MG TABLET be taken by children?

No. MEXAFLO 400MG TABLET is used for adults and is not recommended for children
and adolescents below 18 years of age. Your doctor will decide the correct dose
or select a suitable alternative therapy for your child.

What if I forget totakea dose of MEXAFLO 400MG TABLET?

If you forget to take a dose of MEXAFLO 400MG TABLET, take it as soon as you
remember. However, omit the missed dose if it is almost time for the next dose.
Do not take the medicine twice to make up for the missed dose.

Can MEXAFLO 400MG TABLET be stopped?

Continue taking MEXAFLO 400MG TABLET until your doctor tells you to stop, unless
you experience any unwanted effects, worsening of your condition or any new
symptoms. In such a case, contact your doctor right away. Do not stop taking
MEXAFLO 400MG TABLET just because you feel better. If you do so, your infection
may get worse again.

Can MEXAFLO 400MG TABLET be taken in pregnancy?

MEXAFLO 400MG TABLET is not recommended for use in pregnancy. If you are
pregnant, think you may be pregnant or are planning to get pregnant, consult
your doctor before taking this medicine. Inform your doctor immediately if you
become pregnant during management with MEXAFLO 400MG TABLET.

Can MEXAFLO 400MG TABLET be crushed?

No. MEXAFLO 400MG TABLET should not be broken, crushed or chewed. Simply swallow
it as a whole with a glass of water.

Can I take other medicines with MEXAFLO 400MG TABLET?

Before taking MEXAFLO 400MG TABLET, inform your doctor if you are taking, have
taken or might take any other medicine, including prescri
or any herbal medicine, as these might interact with each other and cause
serious side effects.

Can MEXAFLO 400MG TABLET cause nausea?

Yes. If you feel nauseous, take MEXAFLO 400MG TABLET with or just after meals.
Stick to simple meals. Avoid eating oily or spicy foods. If your symptom gets
worse or persist, contact your doctor immediately.

Can I drive a car after taking MEXAFLO 400MG TABLET?

Do not drive if you experience sleepiness, dizziness or problems with your
eyesight after taking MEXAFLO 400MG TABLET. Consult your doctor if you feel any
side effects during management with MEXAFLO 400MG TABLET that may stop you from
driving or using machines.

Useful Diagnostic Tests

• Bacterial culture
• Microscopic examination
• Completed Blood Count (CBC)