MANFORCE 30/50 Tablet 2's

Introduction About MANFORCE 30/50 TABLET

MANFORCE 30/50 TABLET is a combination of Dapoxetine and Sildenafil,which belong
to the group of medicines called Selective serotonin reuptake inhibitors and
Phosphodiesterase type 5 (PDE5) inhibitors, respectively. It is used in adult
men to help improve blood flow to the penis and to manage early ejaculation by
balancing certain chemicals in the brain.

Before taking MANFORCE 30/50 TABLET, inform your doctor if you have any previous
history of fainting or dizziness due to low blood pressure. You must also inform
your doctor if you have epilepsy, lung problems, mental health problems, or
bleeding disorders before taking MANFORCE 30/50 TABLET as a precaution. MANFORCE
30/50 TABLET is not recommended for use in patients with liver or heart
problems.Avoid taking MANFORCE 30/50 TABLET with heavy meals or with grapefruit
juice.

The most common side effects of taking MANFORCE 30/50 TABLET are flushing,
headache, dizziness, blurred vision, muscle pain, nausea, tiredness, increased
sweating, restlessness, and a decrease in sex drive. Consult your doctor if any
of these side effects trouble you.

Also, inform your doctor immediately if you experience any prolonged painful
penile erections without sexual stimulation (priapism), experience dizziness
upon standing up suddenly, or if you have sudden mood changes or suicidal
thoughts after taking MANFORCE 30/50 TABLET.

Uses Of MANFORCE 30/50 TABLET

It is used by adult men to:

• Help improve blood flow to the penis
• Manage early ejaculation

How MANFORCE 30/50 TABLET Works

MANFORCE 30/50 TABLET contains two medicines called dapoxetine and sildenafil.
Dapoxetine delays ejaculation by blocking the reuptake of a chemical messenger
called serotonin between the nerve cells. This increases the activity of
serotonin within the brain, which therefore increases the time taken to release
the semen (ejaculate) during sexual intercourse.

Sildenafil works by improving the blood supply to the penis. It works by
blocking the effects of certain enzymes (PDE5) in the body that limit blood flow
to the penis. As a result, it relaxes the blood vessels supplying the penis and
improves blood flow.

How to use MANFORCE 30/50 TABLET

Take MANFORCE 30/50 TABLET as advised by your physician. Swallow MANFORCE 30/50
TABLET with a glass of water. Do not chew or crush the medicine. Take MANFORCE
30/50 TABLET, preferably before meals, and at least 30 minutes to 1 hour before
planning to have sexual intercourse. Your doctor will decide the correct dose
and duration of therapy for you depending on your age, body weight, and health
condition.

Side Effects Of MANFORCE 30/50 TABLET

Common

• dizziness, headache
• nausea, vomiting
• feeling irritable, anxious, agitated, or restless
• sensation of numbness, tingling or prickling
• increased sweating
• hot flushes
• diarrhea, constipation, wind, and stomach pain
• problems in sleeping or strange dreams, difficulty in concentration
• tiredness or sleepiness
• blocked nose
• a rise in blood pressure
• decrease in sex drive
• ringing in the ears
• blurred vision, color tinge to vision, visual disturbance
• dry mouth

Uncommon

• fainting
• change in mood, feeling overly excited or feelings of paranoia (feeling threatened)
• feeling confused, disoriented, or unable to think clearly
• abnormal heartbeat (slow or fast heart rate)
• feeling depressed or nervous
• feeling hot, jittery, abnormal, or drunk
• eye problems (eye irritation, pain or redness, watery eyes, double vision, abnormal sensation in the eye, seeing light flashes)
• low blood pressure
• feeling itchy or cold sweats
• spinning sensation
• abnormal taste
• skin rash
• muscle pain
• reduced sense of touch
• signs of inflammation of the lining of the nose, such as a runny nose or sneezing
• upper abdominal pain
• signs of gastroesophageal reflux disease, such as heartburn
• presence of blood in urine or semen
• pain in the arms or legs
• nosebleed

Rare

• penile bleeding
• dry nose
• throat tightness, numbness of the mouth
• temporary decrease in blood flow to the brain
• sudden decrease or loss of hearing
• sudden onset of sleep (Ex. narcolepsy)
• urge to empty the bowel

Stop taking MANFORCE 30/50 TABLET and contact your doctor if you experience any
of the following side effects:

• severe allergic reaction (such as wheeziness, difficulty breathing or dizziness, swelling of the face, lips, eyelids, or throat)
• prolonged or painful erection (priapism)
• chest pain, especially during or after sexual intercourse
• severe skin reactions (blistering of skin around the mouth, genitals or eyes, severe peeling and swelling of skin along with fever)
• sudden decline or loss of vision
• fits or seizures
• fainting or lightheadedness while standing
• mood changes, suicidal thoughts, or a tendency for self-harming

How To Manage Side Effects

!### Diarrhea

Hydrate yourself by drinking plenty of fluids, such as water or fruit juices.
Consuming ORS can also be beneficial. Do not self-manage diarrhea on your own.
Consult your doctor if your diarrhea becomes uncontrollable.

!### Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or
machines completely while you are feeling dizzy. Do not consume excessive
alcohol, as it could aggravate your dizziness. Consult your doctor if your
dizziness worsens or if you feel dizzy upon standing up suddenly.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids, such as
water or electrolytes. Applying a pain-relieving balm to your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate your
headache. Consult your doctor if your headache worsens.

!### Nausea And Vomiting

Take MANFORCE 30/50 TABLET with or just after meals. Stick to simple meals.
Avoid eating oil-rich or spicy foods. Consult your doctor if your vomiting
worsens.

Warning & Precautions

!### Pregnancy

ContraindicatedMANFORCE 30/50 TABLET is not intended for use by women.

!### Breastfeeding

ContraindicatedMANFORCE 30/50 TABLET is not intended for use by women.

!### Driving and Using Machines

ContraindicatedDo not drive or operate any machines if you experience dizziness or blurred
vision after taking MANFORCE 30/50 TABLET.

!### Alcohol

ContraindicatedAvoid consum
dizziness or sleepiness.

!### Kidney

Use with CautionMANFORCE 30/50 TABLET should be used with caution in patients with kidney
problems. Therefore, consult your doctor before taking it.

!### Liver

ContraindicatedMANFORCE 30/50 TABLET is not recommended for use in patients with moderate or
severe liver diseases. Therefore, consult your doctor before taking it.

!### Allergy

ContraindicatedDo not take MANFORCE 30/50 TABLET if you are allergic to Dapoxetine or
Sildenafil.

!### Lungs

Use with CautionMANFORCE 30/50 TABLET should be used with caution in patients with pulmonary
arterial hypertension. Therefore, consult your doctor before taking it.

!### Heart Disease

ContraindicatedMANFORCE 30/50 TABLET is not recommended for use in patients with heart problems
(such as heart failure, low blood pressure, or problems with the heart rhythm).
Therefore, consult your doctor before taking it.

!### Use In Pediatrics

ContraindicatedMANFORCE 30/50 TABLET is not recommended for use in children and adolescents
(below 18 years). Therefore, consult your doctor before taking it.

!### Use In Geriatrics

ContraindicatedMANFORCE 30/50 TABLET is not recommended for use in elderly patients (aged 65
years or older). Therefore, consult your doctor before taking it.

Others

MANFORCE 30/50 TABLET is not recommended for use if you:

• have a history of fainting
• have or ever had signs of m
• have severe depression
• have recently had a stroke
• have low blood pressure
• have signs of retinitis pigmentosa (rare inherited eye disease) such as decreased vision at night or in low light and loss of side vision

Before taking MANFORCE 30/50 TABLET, inform your doctor if you:

• have a history of feeling dizzy due to low blood pressure
• have schizophrenia (a psychiatric disease)
• have epilepsy
• have a history of bleeding or blood clotting problems
• have or are at risk of developing glaucoma
• have sickle cell anemia (an abnormality of red blood cells)
• have leukemia (cancer of blood cells)
• have multiple myeloma (cancer of the bone marrow)
• have a deformity in your penis
• have Peyronie’s disease (the development of fibrous scar tissue in the penis that causes painful erection)
• currently have a stomach ulcer
• have bleeding problems such as hemophilia
• are alcoholic

Interactions

A. Drug-Drug Interactions:

Before taking MANFORCE 30/50 TABLET, inform your doctor if you are taking any of
the following medicines, such as:

• nitrates or amyl nitrites (used for reliving chest pain) Ex. nitroglycerin, isosorbide dinitrite
• other medicines used to manage prostate problems or blood pressure, such as alpha blockers (Ex. silodosin, doxazosin)
• riociguat (a medicine used to manage increased pressure in the lungs)
• medicines used to manage depression (Ex. fluoxetine, sertraline, citalopram, escitalopram, amitriptyline, isocarboxazid, selegiline, nefazodone and St. john’s wort)
• thioridazine (a medicine used to manage a mental disorder called schizophrenia)
• lithium (a medicine used to manage bipolar disorder)
• tryptophan (a medicine used to induce sleep)
• medicines used to manage migraines (Ex. almotriptan, sumatriptan)
• non-steroidal anti-inflammatory drugs (used to manage pain and inflammation) Ex. ibuprofen and aspirin
• tramadol (a medicine used to relieve pain)
• antibiotics (used to manage bacterial infections) Ex. telithromycin, linezolid, erythromycin, and clarithromycin
• medicines used to manage HIV infection (Ex. ritonavir, saquinavir, nelfinavir, atazanavir, amprenavir and fosamprenavir)
• medicines used to manage fungal infections (such as ketoconazole, itraconazole and fluconazole)
• warfarin (a medicine used to manage blood clotting)
• other medicines used to manage erectile dysfunction (such as tadalafil or vardenafil)
• medicines used to manage high blood pressure or chest pain (such as verapamil and diltiazem)
• aprepitant (a medicine that is used to manage nausea)
• medicines used to reduce anxiety and alter mental stability (Ex. morphine, pethidine, alprazolam, midazolam, clonazepam, MDMA (ecstasy) or lysergic acid diethylamide)

B. Drug-Food Interactions:

Avoid drinking grapefruit juice within 24 hours prior to taking MANFORCE 30/50
TABLET, as it may increase the level of MANFORCE 30/50 TABLET in the body. Also,
taking MANFORCE 30/50 TABLET with a heavy meal may delay its onset of action.

Overdosage:

If you or anyone else accidentally took more MANFORCE 30/50 TABLET, consult your
doctor immediately or visit the nearby hospital. The symptoms of an overdose are
nausea and vomiting.

Synopsis

Drug	:	Dapoxetine, Sildenafil
Pharmacological Category	:	Selective serotonin reuptake inhibitors (SSRI), Phosphodiesterase type 5 inhibitors
Therapeutic Indication	:	Problems in erection, to manage early ejaculation
Dosage Forms	:	Tablet

More Information

• Keep MANFORCE 30/50 TABLET out of reach of children
• Store MANFORCE 30/50 TABLET at room temperature

FAQs About MANFORCE 30/50 TABLET

Q: What is MANFORCE 30/50 TABLET used for?

A: MANFORCE 30/50 TABLETis used in adult men to help improve blood flow to the
penis and to manage early ejaculation by balancing certain chemicals in the
brain.

Q: How do I take MANFORCE 30/50 TABLET?

A: Take MANFORCE 30/50 TABLET at least 30 minutes to 1 hour before sexual
intercourse. It should be taken, preferably before meals, for a faster onset of
action. Avoid taking MANFORCE 30/50 TABLET with heavy meals. Swallow the
medicine with a glass of water. Do not crush or chew the medicine.

Q: Can I take MANFORCE 30/50 TABLET daily?

A: MANFORCE 30/50 TABLET is generally prescribed as one dose per day. However,
your doctor will decide whether you can take this medicine daily or not,
depending upon your health condition. Do not take MANFORCE 30/50 TABLET more
than once a day without consulting your doctor.

Q: How long does it take for MANFORCE 30/50 TABLET to start working?

A: It may take around 30 minutes to 1 hour for MANFORCE 30/50 TABLET to start
working; therefore, take this medicine at least one hour before planning to have
sex. This time may vary from person to person depending on their health
condition. Avoid taking heavy meals while taking MANFORCE 30/50 TABLET, as it
could further delay the onset of action.

Q: Who can take MANFORCE 30/50 TABLET?

A: MANFORCE 30/50 TABLET can be used for adult men with sexual problems. It is
not suitable for use in healthy men who do not have any sexual problems or in
men who are not sexually stimulated. It is also not advisable for use in
children or adolescents (aged below 18 years).

Q: What happens if I consume a higher dose of MANFORCE 30/50 TABLET than
prescribed by my doctor?

A: Do not consume a higher dose of MANFORCE 30/50 TABLET than the one prescribed
by your doctor, as it may lead to unwanted side effects. Your doctor will decide
the correct dose for you, depending on your age and disease condition. If the
prescribed dose does not help you, contact your doctor.

Q: Can men be taking MANFORCE 30/50 TABLET father a child?

A: There is no confirmed proof that MANFORCE 30/50 TABLET could affect fertility
in men. However, it is better to consult your doctor before taking MANFORCE
30/50 TABLET if you are planning to father a child.

Q: Is MANFORCE 30/50 TABLET safe?

A: Yes. MANFORCE 30/50 TABLET is safe to use. But inform your doctor immediately
if you experience painful, prolonged erections or chest pain after taking
MANFORCE 30/50 TABLET. It can also cause headache, dizziness, flushing or muscle
pain in some individuals. Contact your doctor if they bother you.

Q: Can I consume alcohol while taking MANFORCE 30/50 TABLET?

A: Avoid consum
reduce the effectiveness of MANFORCE 30/50 TABLET.

Q: How long do the effects of MANFORCE 30/50 TABLET last?

A: The effects of MANFORCE 30/50 TABLET would normally last for 4 hours.
However, this time may vary from person to person depending on their age and
health condition. Consult your doctor if the effects of MANFORCE 30/50 TABLET do
not last long.

Q: Can MANFORCE 30/50 TABLET make you last longer?

A: Yes. MANFORCE 30/50 TABLET delays the release of sperm (ejaculation) in
patients suffering from premature ejaculation.

Q: Will taking MANFORCE 30/50 TABLET affect my sexual life?

A: Long-term use of MANFORCE 30/50 TABLET may negatively impact your sexual
life. It may cause sexual problems, such as a decrease in sex drive. Talk to
your doctor if you are facing any sexual problems while taking MANFORCE 30/50
TABLET.

Q: How does MANFORCE 30/50 TABLET work?

A: MANFORCE 30/50 TABLET contains two medicines called dapoxetine and
sildenafil. Dapoxetine delays ejaculation by blocking the reuptake of a chemical
messenger called serotonin between the nerve cells. This increases the activity
of serotonin within the brain, which therefore increases the time taken to
release the semen (ejaculate) during sexual intercourse.

Sildenafil works by improving the blood supply to the penis. It works by
blocking the effects of certain enzymes (PDE5) in the body that limit blood flow
to the penis. As a result, it relaxes the blood vessels supplying the penis and
improves blood flow.

Q: Can I stop taking MANFORCE 30/50 TABLET on my own without consulting a
doctor?

A: Do not stop taking MANFORCE 30/50 TABLET without consulting your physician,
as sudden discontinuation of MANFORCE 30/50 TABLET may cause withdrawal symptoms
like sleeping problems or dizziness.

Q: Can MANFORCE 30/50 TABLET cause bipolar disorder?

A: MANFORCE 30/50 TABLET may cause mood changes in some individuals. Inform your
doctor immediately if you experience any sudden changes in mood. Also, it is
important to inform you doctor if you already have bipolar disorder as a
precaution before starting management with MANFORCE 30/50 TABLET.