Lupisulin R 40IU Injection 1X10ml

Introduction About LUPISULIN R 40IU INJECTION

LUPISULIN R 40IU INJECTION contains Human Insulin which belongs to the group of
medicines called Antidiabetic agents. It improves glycemic control in patients
with diabetes mellitus (both type I and type II). It helps your body to make
utilize of the circulating blood glucose by transporting the circulating glucose
from the blood into the muscles and fat tissues.

Talk to your doctor before starting therapy with LUPISULIN R 40IU INJECTION if
you have any liver, kidney or heart problems. You must also inform your doctor
if you have a history of stroke, any infection in the recent days, perform
intense exercise or planning to go abroad (as the mealtime and injection timings
may vary) as a precaution.

Do not use this medicine if you have hypoglycemia (low blood sugar levels).
Consult your doctor before using this medicine if you are pregnant or
breastfeeding. Along with the management, carefully follow the instructions
given by your doctor regarding the mealtime and exercise (such as how often and
how much to do).

Carefully follow the instructions given by the doctor in case of
self-administration. Do not mix or change your insulin unless your doctor tells
you to do so.

The most common side effects of receiving LUPISULIN R 40IU INJECTION are low
blood sugar levels, pain, redness, itching, swelling or thickening at the
injection site, lump formation under the skin and swelling of body parts.
Consult your doctor if any of these side effect troubles you.

Uses Of LUPISULIN R 40IU INJECTION

• Improves glycaemic control in patients with diabetes mellitus (both type I and type II)

How LUPISULIN R 40IU INJECTION Works

LUPISULIN R 40IU INJECTION helps your body to make utilise of the circulating
blood glucose. It helps in the transport of glucose from the blood into the
muscles and fat tissues. It also stops the production of glucose by the liver.
As a result, it controls blood sugar levels and improve glycemic control in
patients with diabetes mellitus.

How to use LUPISULIN R 40IU INJECTION

Use LUPISULIN R 40IU INJECTION exactly as advised by your doctor.

For Injections: Injections (supplied as vials or ampoules) must be
administered only a doctor or a nurse into the vein (intravenously) or beneath
the skin (subcutaneously). Your doctor will decide correct dose, frequency of
administration and the injection site depending upon your age, body weight and
health condition.

For Pre-filled syringe or insulin pens:

Inject this medicine exactly as instructed by your doctor. It should be injected
beneath the skin (subcutaneously). Carefully follow the instructions provided by
your doctor if you are administering it by yourself.

• Prior to the administration, rotate the device well for 10 times between your palms and invert 10 times, until the liquid forms a uniform mixture
• Do not shake the medicine vigorously, as it may form a froth
• Insert a fresh needle before injection. Make sure that the medicine does not contain any lumps or air bubbles in it
• After injecting the medicine, remove the needle from the pen and dispose it immediately
• Do not share your needle or disposable pens or pre-filled syringe with anyone to avoid the risk of spreading infections
• Dispose the pen or pre-filled syringe, once it is empty
• Avoid repeatedly injecting the medicine at the same site to manage skin damage. Instead, the injection site should be rotated. Make sure to consult your doctor before changing the injection site as a precaution.

LUPISULIN R 40IU INJECTION should not be mixed with any other insulins before
use. Do not stop therapy with LUPISULIN R 40IU INJECTION without consulting your
doctor.

Side Effects Of LUPISULIN R 40IU INJECTION

Common

• Injection site reactions (such as pain, redness, itching or swelling)
• Lipodystrophy (shrinkage of fat tissues beneath the skin)
• Lumps under the skin
• Edema (swelling of face, hands and legs)
• Low blood sugar levels (signs include tiredness, hunger, nausea, headache, nervousness, cold sweats, fast heartbeat)

Consult your doctor immediately if you experience any of the following side
effects:

• signs of heart failure (such as shortness of breath, chest pain, swelling of body parts, sudden weight gain)
• serious allergic reaction (such as hives, swelling of the face, lips, tongue or throat causing difficulty in breathing or swallowing)

How To Manage Side Effects

!### Hypoglycemia

Managing hypoglycemia, or low blood sugar, involves prompt action to raise blood
glucose levels and manage complications. When experiencing hypoglycemia,
individuals should quickly consume a source of rapidly-absorbed carbohydrates,
such as glucose tablets, fruit juice, or regular soda. Waiting for about 15
minutes and rechecking blood sugar levels is crucial to ensure they rise to a
safe range. If hypoglycemia persists, additional carbohydrate intake may be
necessary. Once blood sugar levels stabilize, a small snack containing both
carbohydrates and protein can help sustain them. Regular monitoring and
consultation with a healthcare professional are essential for developing a
personalized plan to manage hypoglycemia effectively. In severe cases, emergency
assistance may be required.

!### Injection Site Reactions

Managing injection site reactions is essential for individuals who regularly
administer injections. To alleviate discomfort and minimize potential issues, it
is crucial to follow proper injection techniques. Rotate injection sites to
manage overuse of a single area, allowing tissues to heal. Use a clean, sterile
needle and syringe for each injection. Apply an ice pack to the injection site
before and after administration to reduce pain and swelling. If redness,
swelling, or irritation persists, consult a healthcare professional for
guidance. It is essential to report any severe or persistent reactions to ensure
appropriate adjustments to the injection routine and to manage potential
complications.

Warning & Precautions

!### Pregnancy

Consult your doctorConsult your doctor before undergoing therapy with LUPISULIN R 40IU INJECTION if
you are pregnant, think you may be pregnant or planning to have a baby.

!### Breastfeeding

Consult your doctorConsult your doctor before undergoing therapy with LUPISULIN R 40IU INJECTION if
you are breastfeeding.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if your ability is affected by LUPISULIN R
40IU INJECTION.

!### Alcohol

Consult your doctorAvoid consum
INJECTION as it may make this medicine less effective.

!### Kidney

Use with CautionLUPISULIN R 40IU INJECTION should be used with caution in patients with kidney
problems. Therefore, consult your doctor before administration.

!### Liver

Use with CautionLUPISULIN R 40IU INJECTION should be used with caution in patients with liver
problems. Therefore, consult your doctor before administration.

Allergy

ContraindicatedTalk to your doctor before receiving LUPISULIN R 40IU INJECTION if you are
allergic to Human insulin or to any other insulin types.

!### Heart Disease

Use with CautionLUPISULIN R 40IU INJECTION should be used with caution in patients with heart
problems. Therefore, consult your doctor before administration.

!### Use In Pediatrics

Monitoring requiredLUPISULIN R 40IU INJECTION should be used in children and in adolescents (aged
below 18 years) only if prescribed by the physician. Therefore, consult your
doctor before administration.

!### Use In Geriatrics

Use with CautionLUPISULIN R 40IU INJECTION should be used with caution among the elderly
patients (aged 65 years or above). Therefore, consult your doctor before
administration.

Others

LUPISULIN R 40IU INJECTION is not recommended for use if you:

• have or at risk of developing hypoglycaemia (low blood sugar levels)

Talk to your doctor before receiving LUPISULIN R 40IU INJECTION if you:

• have diabetes that is well controlled by the current insulin therapy
• recently became ill or had any infections
• perform intense exercise or physical activity
• are planning to go abroad (as mealtime and injection timings may get changed)
• have a history of stroke

Interactions

A. Drug-Drug interactions:

Before LUPISULIN R 40IU INJECTION is administered, inform your doctor if you are
taking any of the following medicines such as:

• Other antidiabetic agents (Ex. glimepiride, glyburide, gliclazide, rosiglitazone, pioglitazone)
• Anti-asthmatic agents (Ex. salbutamol or terbutaline)
• corticosteroids (used to manage pain and inflammation) Ex. hydrocortisone, prednisolone
• thyroid hormones (such as thyroxine, levothyroxine)
• thiazide diuretics (Ex. hydrochlorothiazide, chlorothiazide)
• pain killers (such as aspirin)
• Antihypertensive agents (such as atenolol, propranolol, captopril, enalapril, ramipril, lisinopril, losartan, valsartan, olmesartan, telmisartan)
• growth hormone (used to increase growth)
• octreotide (used to manage diarrhea)
• lanreotide (a medicine used to manage abnormal body growth)
• danazol (a medicine for uterine problems)
• antidepressants (such as moclobemide, isocarboxazid, phenelzine, selegiline, tranylcypromine)

Overdosage:

If you or anyone else accidentally took more LUPISULIN R 40IU INJECTION, consult
your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Human Insulin
Pharmacological Category	:	Insulin Preparations
Therapeutic Indication	:	Diabetes mellitus
Dosage Forms	:	Injection, Cartridge, Disposable pen

More Information

• Keep LUPISULIN R 40IU INJECTION out of the sight and reach of children
• Before use: Store LUPISULIN R 40IU INJECTION in the refrigerator (between 2-8?)
• In Use: Store at room temperature after opening for up to 28 days

FAQs About LUPISULIN R 40IU INJECTION

Q: What is LUPISULIN R 40IU INJECTION used for?

A: LUPISULIN R 40IU INJECTION improves glycemic control in patients with
diabetes mellitus (both type I and type II). It helps your body to make utilize
of the circulating blood glucose by transporting the circulating glucose from
the blood into the muscles and fat tissues.

Q: How LUPISULIN R 40IU INJECTION should be administered?

A: LUPISULIN R 40IU INJECTION should be administered beneath the skin or into
the vein. Do not inject it in your vein in case if you are administering this
medicine on your own.

Q: How long should I take LUPISULIN R 40IU INJECTION?

A: You need to take LUPISULIN R 40IU INJECTION as long as your doctor prescribes
you the medicine. Your doctor will decide the correct dose and duration of
therapy for you depending upon your age, body weight and disease condition.

Q: What to do if I forgot to take a dose of LUPISULIN R 40IU INJECTION?

A: If you forgot to take a dose of LUPISULIN R 40IU INJECTION, take it as soon
as you remember. However, if it is time for the next dose of LUPISULIN R 40IU
INJECTION, skip the missed dose and take the next one regularly. Do not take a
double dose of LUPISULIN R 40IU INJECTION to compensate the missed ones.

Q: What are the most common side effects of taking LUPISULIN R 40IU INJECTION?

A: The most common side effects of receiving LUPISULIN R 40IU INJECTION are low
blood sugar levels, pain, redness, itching, swelling or thickening at the
injection site, lump formation under the skin and swelling of body parts.
Consult your doctor if any of these side effect troubles you.

Q: Can I stop therapy with LUPISULIN R 40IU INJECTION without consulting your doctor?

A: No. You should not stop therapy with LUPISULIN R 40IU INJECTION without
consulting your doctor because it may lead to reversal of symptoms. If you feel
better after using LUPISULIN R 40IU INJECTION, consult your doctor for advice.

Q: Will taking a higher dose of LUPISULIN R 40IU INJECTION be more effective?

A: No, taking a higher dose of LUPISULIN R 40IU INJECTION will not be effective
rather it can lead to toxicity. Always take the dose prescribed by your doctor.
If the prescribed dose is not effective for you, consult your doctor for advice.
Your doctor might increase the dose or suggest an alternative therapy.

Q: Can I take medication for high blood pressure along with LUPISULIN R 40IU INJECTION?

A: It is not advisable to take medicines to control blood pressure while taking
LUPISULIN R 40IU INJECTION without consulting your doctor. Therefore, consult
your doctor before taking any antihypertensive medications along with LUPISULIN
R 40IU INJECTION as they have known interactions with LUPISULIN R 40IU
INJECTION.

Q: Can LUPISULIN R 40IU INJECTION be used in pregnant women?

A: Consult your doctor before undergoing therapy with LUPISULIN R 40IU INJECTION
if you are pregnant, think you may be pregnant or planning to have a baby.

Q: How much LUPISULIN R 40IU INJECTION should I take?

A: LUPISULIN R 40IU INJECTION should be used only under medical supervision.
Your doctor will decide the correct dose and duration of therapy for you
depending upon your age, body condition and severity of the disease condition.

Useful Diagnostic Tests

• HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
• Blood Glucose Fasting (FBS)
• Insulin-Fasting
• medicalslot Diabetic Checkup
• Advance Diabetes Monitoring (Senior Female)
• Jaanch Diabetic Profile Basic