Lubowel 24Mcg Capsule 15'S

Introduction About LUBOWEL 24MCG CAPSULE

LUBOWEL 24MCG CAPSULE contains Lubiprostone which belongs to the group of
medicines called Laxatives. It is used to manage chronic idiopathic
constipation, opioid-induced constipation in patients with chronic non-cancer
pain and it is also used to manage irritable bowel syndrome with constipation in
women above 18 years of age.

Constipation is a condition in which a person has uncomfortable or occasional
bowel movements. Usually, a person is constipated when bowel movements result in
the passage of small amounts of hard, dry stool, usually fewer than three times
a week. However, normal stool elimination may involve a bowel movement three
times a day or multiple times a week, it depends on the person.

LUBOWEL 24MCG CAPSULE is not recommended for use in patients having mech
gastrointestinal obstruction or severe diarrhoea. Your doctor may take several
blood tests prior to management with LUBOWEL 24MCG CAPSULE to understand the
existing condition.

LUBOWEL 24MCG CAPSULE is not recommended for use in pregnant and breastfeeding
women. LUBOWEL 24MCG CAPSULE is not recommended for use in children and
adolescents (aged 18 years and below) and should be used with caution in elderly
patients.

The most common side effects of taking LUBOWEL 24MCG CAPSULE are nausea,
diarrhoea, headache, abdominal pain, tiredness, dry mouth and flatulence.
Consult your physician for advice if any of the side effects worsen.

Uses Of LUBOWEL 24MCG CAPSULE

Manages,

• chronic idiopathic constipation
• opioid-induced constipation in patients with chronic non-cancer pain
• irritable bowel syndrome with constipation in women

How LUBOWEL 24MCG CAPSULE Works

LUBOWEL 24MCG CAPSULE works by increasing the secretion of fluids in the
intestine, which in turn increases the motility of the intestine, thereby making
the stool soft, easier to pass and reduce the feeling of difficulty and
uncomfortable bowel movements that occurs with constipation.

How to use LUBOWEL 24MCG CAPSULE

Take LUBOWEL 24MCG CAPSULE as advised by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine. The correct dose and
duration for you will be decided by your physician for you depending on your
age, body weight and disease condition.

Side Effects Of LUBOWEL 24MCG CAPSULE

Common

• nausea
• diarrhoea
• headache, dizziness
• abdominal pain and swelling
• flatulence
• increased heart rate
• edema
• tiredness, dry mouth
• chest discomfort/pain
• shortness of breath
• abdominal discomfort
• hot flushes
• upset stomach
• excessive sweating

Rare

• vomiting
• occasional fainting
• muscle spasms

Stop taking LUBOWEL 24MCG CAPSULE and contact your physician immediately if you
experience any of the following side effects:

• severe diarrhoea
• severe nausea

How To Manage Side Effects

Nausea:

Take LUBOWEL 24MCG CAPSULE with food. Stick to simple meals while taking this
medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep
immediately after eating. Consult your doctor if the symptom does not improve.

Diarrhoea:

Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating
high-fat or spicy foods. Try to avoid taking any medicine on your own to manage
diarrhoea and consult your doctor if the symptom gets worse.

Stomach pain:

Try to rest and relax. Eat and drink slowly or try to have lesser and more
frequent meals. Keep a heating pad on your stomach. If the symptom does not
improve, contact your physician for advice.

Headache:

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to
be relaxed and stress-free. Apply pain relieving balm on your forehead if
necessary. Consult your doctor if the symptom does not improve.

Dizziness:

Lie down until the dizziness is gone, then get up slowly. Move slowly and
carefully, do not hurry. Get adequate rest. Drink plenty of water and other
fluids. Avoid coffee, cigarettes, alcohol and drugs. Consult your doctor if the
symptom gets worse.

Warning & Precautions

!### Pregnancy

LUBOWEL 24MCG CAPSULE is not recommended for use in pregnant women and in women
of childbearing potential not using contrace
taking it.

!### Breastfeeding

LUBOWEL 24MCG CAPSULE is not recommended to use in breastfeeding women as it is
not known if it may pass through breast milk. Consult your physician before
taking it.

!### Driving and Using Machines

Do not drive or operate any machinery if you experience any side effects that
may impair your ability to drive or operate machines.

!### Liver

LUBOWEL 24MCG CAPSULE should be taken with caution in patients with moderate or
severe liver impairment and your doctor may adjust the dose. Consult your
physician before taking LUBOWEL 24MCG CAPSULE.

!### Allergy

Do not take LUBOWEL 24MCG CAPSULE if you are allergic to Lubiprostone or any
other ingredients of this medicine.

Others

LUBOWEL 24MCG CAPSULE is not recommended for use if you:

• have a mech
• have severe diarrhoea
• intolerance to some sugars such as sorbitol

Use in pediatrics:

LUBOWEL 24MCG CAPSULE is not recommended for use in children and adolescents
(aged 18 years and below) as the safety and effectiveness of LUBOWEL 24MCG
CAPSULE have not been studied in this group. Consult your child’s physician for
advice.

Use in geriatrics:

In elderly patients, LUBOWEL 24MCG CAPSULE should be used with caution. Consult
your physician before taking it.

Interactions

A. Drug-Drug interactions:

Before taking LUBOWEL 24MCG CAPSULE, inform your physician if you are taking any
of the following medicines:

• methadone (used to manage pain and drug addiction)

Overdosage:

If you or anyone else accidentally takes too much of LUBOWEL 24MCG CAPSULE,
consult your physician immediately or visit the nearby hospital. The symptoms of
overdosage of LUBOWEL 24MCG CAPSULE are nausea, diarrhoea, vomiting, dizziness,
headache, abdominal pain, flushing/hot flash, retching, dyspnea, pallor, stomach
discomfort, anorexia, physical weakness, chest discomfort, dry mouth, increased
sweating and syncope.

Synopsis

Drug	:	Lubiprostone
Pharmacological Category	:	Laxatives
Therapeutic Indication	:	Chronic idiopathic constipation, Opioid-induced constipation in patients with chronic non-cancer pain and irritable bowel syndrome with constipation
Dosage Forms	:	Capsule

More Information

• Keep LUBOWEL 24MCG CAPSULE out of reach of children
• Store at a temperature, not more than 25°C

FAQs About LUBOWEL 24MCG CAPSULE

Can LUBOWEL 24MCG CAPSULE cause diarrhoea?

Diarrhoea is the common side-effect of LUBOWEL 24MCG CAPSULE. Avoid eating
high-fat or spicy foods. Try to avoid taking any medicine on your own to manage
diarrhoea and consult your doctor if the symptom gets worse.

Does prolonged use of LUBOWEL 24MCG CAPSULE cause dehydration?

Prolonged use of LUBOWEL 24MCG CAPSULE may cause dehydration. Severe dehydration
may in turn cause weakness, fainting, tremors and blurry vision. Consult your
physician immediately for advice if you experience these symptoms. Drink enough
fluids to avoid dehydration.

Who should not take LUBOWEL 24MCG CAPSULE?

LUBOWEL 24MCG CAPSULE should not be used if you have a blockage in the digestive
tract or have severe diarrhoea, pregnant or breastfeeding women. Consult your
physician before taking LUBOWEL 24MCG CAPSULE.

What if I forget to take a dose of LUBOWEL 24MCG CAPSULE?

If you forget a dose of LUBOWEL 24MCG CAPSULE, take it as soon as you remember.
However, if it is almost time for the next dose, skip the missed dose and take
the next dose at the prescribed time. Do not double the dose to make up for the
missed dose as this may increase the chances of developing side effects.

Can I stop taking LUBOWEL 24MCG CAPSULE on my own when I feel better?

No, do not stop taking LUBOWEL 24MCG CAPSULE without consulting your physician
even if you are feeling better. If you stop taking LUBOWEL 24MCG CAPSULE, your
symptoms may return. Therefore, for better and complete management, it is
advised to continue the management for the prescribed duration.

Can LUBOWEL 24MCG CAPSULE be used in pregnant women?

LUBOWEL 24MCG CAPSULE is not recommended for use in pregnant women and in women
of childbearing potential not using contrace
taking LUBOWEL 24MCG CAPSULE if you are pregnant or planning to get pregnant.

Useful Diagnostic Tests

• Complete Blood Count
• Colonoscopy
• Ultrasound