JO SET Syrup 30ml

Introduction About JO SET SYRUP

JO SET SYRUP contains Ondansetron which belongs to a group of medicines called
Anti-emetics. JO SET SYRUP is used to manage nausea and vomiting in children
caused by cancer chemotherapy, radiation therapy, and surgery.

Before giving JO SET SYRUP, to your child, inform your doctor if your child have
or had severe constipation, heart problems, liver, kidney problems, imbalance
with the levels of salts in your blood, (potassium, sodium, and magnesium), or
have been scheduled for any surgery. During the therapy, your doctor would
regularly monitor your child’s health to avoid the risk of side effects.

Your doctor will prescribe the right dose and duration depends on the child’s
age, body weight and health condition, so stick to the dose, time, and duration
prescribed by the doctor.  Minor and temporary side effects may be experienced
after the intake of this medicine. These includes headache, flushing and
constipation.

Generally, these effects subside once the child’s body adapts to the medicine.
However, in case of prolonged or bothersome events, consult your doctor
immediately without any delay. Inform your doctor about your child’s complete
medical history including any previous episodes of allergies.

Uses Of JO SET SYRUP

• Used to manage nausea and vomiting in children caused by cancer chemotherapy, radiation therapy, and surgery

How JO SET SYRUP Works

JO SET SYRUP is a serotonin 5-HT3 receptor antagonist (specific chemical
receptor), and it works by blocking the action of serotonin, a natural substance
that may cause nausea and vomiting.

How to use JO SET SYRUP

Always give this JO SET SYRUP to your child as instructed by your doctor. Shake
well before use. It is for pediatric use. Your doctor will prescribe the right
dose depends on your child’s age body weight and disease condition.

Side Effects Of JO SET SYRUP

Common

• headache
• constipation
• weakness
• tiredness
• chills and drowsiness

Rare

Stop giving JO SET SYRUP and contact your doctor immediately if your child
experience any of the following side effects:

• severe allergic reaction which may include a red and lumpy skin rash (hives), difficulty with breathing, sudden wheezing, swelling of the face, mouth, lips or eyelids or a high temperature (fever)

How To Manage Side Effects

Headache:

Give plenty of water and apply a wet or cold cloth on child’s forehead. Apply
pain balm to head to ease off the pain. If there is no improvement in the
symptom, contact your doctor.

Constipation:

Give more fiber-rich foods like green leafy vegetables and fruits. Give lots of
water. If there is no improvement in the symptom, contact your doctor.

Warning & Precautions

!### Driving and Using Machines

Do not allow your child drive or play outdoors, as JO SET SYRUP may cause
dizziness or blurry vision. Consult your doctor before giving JO SET SYRUP.

!### Kidney

JO SET SYRUP should be used with caution if the child has kidney disease.
Consult your doctor before giving JO SET SYRUP.

!### Liver

JO SET SYRUP should be used with caution if the child has liver disease. Consult
your doctor before giving JO SET SYRUP.

!### Allergy

Do not use JO SET SYRUP if your child is allergic (hypersensitive) to
Ondansetron or any other ingredients of this medicine.

!### Heart Disease

JO SET SYRUP should be used with caution if your child has any heart disease. If
needed, dose will be adjusted accordingly. Consult your doctor for advice.

Others

Before giving JO SET SYRUP, inform your doctor if your child had or have:

• problems with the levels of salts in the blood, such as potassium, sodium, and magnesium
• severe constipation or gut problems like blockage
• are intolerant to some sugars (Ex. fructose intolerance)

Use in pediatrics:

Your doctor will prescribe the right dose and frequency depends on your child’s
age, body weight and disease condition. Consult your doctor before giving JO SET
SYRUP.

Interactions

A. Drug-Drug Interactions:

Before using JO SET SYRUP, inform your doctor if your child is taking any of the
following medicine:

• medicines used to manage fits/epilepsy (ex. phenytoin, carbamazepine)
• medicines used to manage lung infections (ex. rifampicin)
• tramadol (used to manage severe pain)
• medicines used to manage heart problems such as abnormal heart beats (anti-arrhythmic   ex. amiodarone)
• cancer medicines (ex. doxorubicin, daunorubicin and monoclonal, trastuzumab)
• medicines used to manage infections (erythromycin, ketoconazole)

Overdosage:

If your child accidentally takes too much of JO SET SYRUP, consult your doctor
immediately or visit the nearby hospital.

Synopsis

Drug	:	Ondansetron
Pharmacological Category	:	Serotonin antagonist
Therapeutic Indication	:	Nausea and Vomiting in patients (undergoing chemotherapy, radiotherapy, surgery)
Dosage Forms	:	Tablet, Injection, Dispersible Tablet, Syrup, Suspension, Oral strips, Lozenges, Pastille

More Information

• Keep the medicine out of reach in children
• Store JO SET SYRUP at room temperature

FAQs About JO SET SYRUP

Q: What JO SET SYRUP is used for?

A: JO SET SYRUP is generally given before any major surgery or before
chemotherapy and radiotherapy sessions. In case your child is about to undergo
any of the above procedures, the doctor may ask you to give JO SET SYRUP to your
child to manage vomiting post-procedure.

Q: What if my child takes too much JO SET SYRUP?

A: JO SET SYRUP is unlikely to cause harm if you give an extra dose by mistake.
However, you must still tell your child’s doctor immediately.

Q: Can other medicines be given at the same time as JO SET SYRUP?

A: JO SET SYRUP may interact with other medicines or substances. Tell your
doctor about any other medicines your child is taking before starting JO SET
SYRUP. Also, check with your child’s doctor before giving any medicine to your
child.

Q: For how long should I give JO SET SYRUP?

A: Your doctor might advise you on how long your child should continue to take
JO SET SYRUP. You will need to consult your doctor from time to time to review
the child’s management and assess the symptoms.

Q: What are the side effects are seen with JO SET SYRUP?

A: The most common side effects include JO SET SYRUP are headache, flushing
(feeling of warmth), constipation. Consult your doctor if the above side effects
persist for a long time.