Goodova 50mg Capsule 5'S

Introduction About GOODOVA 50MG CAPSULE

GOODOVA 50MG CAPSULE is a combination of Clomiphene Citrate and Melatonin, which
belong to the groups of medicines called Ovarian stimulants and Nutraceutical
products, respectively. It is used in the management of female infertility,
which means not being able to get pregnant after at least one year of trying (or
6 months if the woman is over age 35) or a woman who keeps having miscarriages.
It can result from age, physical problems, hormone problems and lifestyle or
environmental factors and present as abnormal periods, heavy menstrual bleeding
or lighter than usual, irregular periods, the number of days in between each
period varying each month, painful periods or periods that suddenly stop.

Before starting GOODOVA 50MG CAPSULE, your doctor should check for any other
causes of fertility problems. GOODOVA 50MG CAPSULE is not recommended for use in
patients with liver disease, unusual menstrual bleeding where the cause is not
known, hormone-dependent cancers or ovarian cysts. Before taking GOODOVA 50MG
CAPSULE, inform your doctor if you have early menopause or stopped having
periods because you are underweight, have uterine fibroids, polycystic ovaries
or swollen ovaries, hypertriglyceridemia, epilepsy, autoimmune disease, diabetes
or smoking habit.

GOODOVA 50MG CAPSULE is generally not recommended for use in pregnant women,
breastfeeding women, children, adolescents (below 18 years of age) and
post-menopausal women. The common side effects of GOODOVA 50MG CAPSULE are
flushing, pelvic discomfort or abdominal distention or bloating, nausea and
vomiting, painful breasts and headaches. If any of these become worse, contact
your doctor.

Uses Of GOODOVA 50MG CAPSULE

• Used to manage female infertility

How GOODOVA 50MG CAPSULE Works

GOODOVA 50MG CAPSULE is a combination of Clomiphene citrate that selectively
binds to estrogen hormone receptors in the brain, ovary, endometrium and cervix
to increase the secretion of the luteinizing hormone as well as a
follicle-stimulating hormone for the release of a mature egg from ovaries and
Melatonin improves egg quality by reducing the damage, which in turn leads to
higher fertilization rate. This collective action is useful in managing female
infertility.

How to use GOODOVA 50MG CAPSULE

Take GOODOVA 50MG CAPSULE as advised by your physician. Swallow the medicine
with a glass of water. Do not crush or chew the medicine. The correct dose and
duration for you will be decided by your doctor, depending on your age, body
weight and disease condition.

Side Effects Of GOODOVA 50MG CAPSULE

Common

• Vasomotor flushes
• Pelvic discomfort or abdominal distention/bloating
• Nausea
• Vomiting
• Discomfort and pain in the breast
• Headache
• Drowsiness

Uncommon

• Blurred vision
• Cloudy lenses in the eye
• Increased pain with periods, heavy periods or bleeding between periods
• Irritability, nervousness, restlessness, abnormal dreams and anxiety
• Dizziness
• Increased blood pressure
• Stomach pain with indigestion, ulcers in mouth, dry mouth
• Itching, rash, dry skin
• Passing glucose, excess protein in the urine
• Increase in weight

Rare

• Constipation
• Depression
• Tiredness
• Hair loss/dry hair
• Increased urinary frequency or volume
• Difficulty in falling asleep
• Vaginal dryness
• Head spinning sensation
• Increased fat molecules (triglycerides) in the blood
• Altered mood, aggression, increased sex drive
• Restless legs syndrome
• Pins and needles sensation
• Watery eyes
• Excessive saliva and bad breath
• Nail disorder
• Joint pain and muscle spasms
• Thirst
• Abnormal levels of electrolytes in the blood

Stop taking GOODOVA 50MG CAPSULE and contact your doctor immediately if you
experience any of the following side effects:

• Signs of an allergic reaction (skin rash, itching, difficulty breathing, shortness of breath, swelling of your face, lips, throat or tongue, cold clammy skin, palpitations, dizziness, weakness or fainting)
• Signs of stroke (numbness, weakness or paralysis on one side of your body, slurred speech, sudden blurred vision, confusion or unsteadiness)
• Over-stimulation of the ovary (pain in the pelvis, stomach or calves, swelling or feeling bloated, passing less urine, difficulty in breathing or an increase in weight)
• Blurring of vision or spots or flashes in front of the eyes.
• Signs of a liver problem (yellowing of eyes or skin)
• Sudden and severe headaches
• Psychosis
• Chest pain and feeling your heartbeat ('pounding chest')
• Reduced number of white blood cells and platelets, which increases the risk of bleeding or bruising
• Blood (red blood cells) in the urine

How To Manage Side Effects

!### Bloating

Eat smaller and more frequent meals, drink a lot of water and go for small walks
after each meal. In the event of no improvement, consult your doctor.

Headache

Try to relax and rest yourself. Apply pain balm to the head to ease the pain.
Sip on some hot water or ginger tea. In case of no improvement, contact your
doctor for advice.

!### Nausea And Vomiting

Take this medicine with meals or just after meals. Stick to simple meals and
avoid eating oil-rich or spicy foods. In case of no improvement, consult your
doctor.

!### Stomach Pain

Take a break for relaxation. Eat and drink slowly or try to have smaller and
more frequent meals. Keep a heating pad on your stomach. In the event of no
improvement, consult your doctor.

Warning & Precautions

!### Pregnancy

ContraindicatedGOODOVA 50MG CAPSULE is not recommended for use in pregnant women or in women
who think they may be pregnant. You should take a pregnancy test before taking
the medicine. Consult your doctor for advice.

!### Breastfeeding

ContraindicatedGOODOVA 50MG CAPSULE is not recommended for breastfeeding women as it is
excreted in human milk and poses a risk to the sucking child. Therefore, consult
your doctor for advice.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if you feel drowsy or blurred vision after
taking GOODOVA 50MG CAPSULE.

!### Alcohol

Consult your doctorAvoid consuming alcohol while taking GOODOVA 50MG CAPSULE as it can impair sleep
and concentration and potentially worsen side effects such as headache and
tiredness.

!### Kidney

Use with CautionGOODOVA 50MG CAPSULE should be used cautiously in patients having impaired
kidney function. Consult your doctor for advice.

!### Liver

ContraindicatedGOODOVA 50MG CAPSULE is not recommended for use in patients having or ever had
liver disease. Consult your doctor for advice.

!### Allergy

ContraindicatedDo not take GOODOVA 50MG CAPSULE if you are allergic to Clomiphene citrate or
Melatonin.

!### Use In Pediatrics

ContraindicatedGOODOVA 50MG CAPSULE is generally not recommended for use in children and
adolescents (under 18 years of age). Consult your doctor for advice.

!### Use In Geriatrics

ContraindicatedGOODOVA 50MG CAPSULE is not recommended for use in women who have already gone
through menopause (post-menopausal).

Others

GOODOVA 50MG CAPSULE is not recommended for use if you:

• Have unusual menstrual bleeding due to an unknown cause
• Have hormones-dependent cancer
• Have an ovarian cyst

Before taking GOODOVA 50MG CAPSULE, inform your doctor if you:

• Have early menopause or have been told you are infertile
• Are periods stopped because of under-weight
• Have uterine fibroids
• Have polycystic ovaries or swollen ovaries
• Have hypertriglyceridemia or a family history of hypertriglyceridemia
• Have epilepsy
• Have an autoimmune disease
• Have diabetes or impaired glucose tolerance
• Have a smoking habit

Interactions

A. Drug-Drug interactions:

Before taking GOODOVA 50MG CAPSULE, inform your doctor if you are taking any of
the following medicine:

• Fluvoxamine (used in depression and obsessive-compulsive disorder management)
• Psoralens (used in managing skin disorders)
• Cimetidine (used for managing stomach ulcers)
• Estrogens (used to manage pregnancy or hormone replacement preparations)
• Ciprofloxacin, enoxacin, gemifloxacin (used in the management of bacterial infections)
• Rifampicin (used to manage tuberculosis)
• Carbamazepine (used in the management of epilepsy)
• Medicines used to induce sleep (Ex. midazolam, temazepam, zaleplon, zolpidem, zopiclone)
• Warfarin (used to manage blood clotting)

Overdosage:

If you or anyone else accidentally take too much of GOODOVA 50MG CAPSULE,
consult your doctor immediately or visit the nearby hospital. Symptoms of
overdose are pelvic or stomach pain, bloating, drowsiness, headache, dizziness
and nausea.

Synopsis

Drug	:	Clomiphene citrate, Melatonin
Pharmacological Category	:	Estrogen receptor modulators, Hormones
Therapeutic Indication	:	Female infertility
Dosage Forms	:	Tablet, Capsule, Softgel Capsule

More Information

Storage

• Keep GOODOVA 50MG CAPSULE out of reach from children
• Store at room temperature

FAQs About GOODOVA 50MG CAPSULE

Q: What is the use of GOODOVA 50MG CAPSULE?

A: GOODOVA 50MG CAPSULE is a medicine used to manage female infertility. It
increases the chances of pregnancy in women who have a problem with ovulation
(the release of an egg) or have a condition called polycystic ovary syndrome
(PCOS).

Q: How long should I take GOODOVA 50MG CAPSULE?

A: Take GOODOVA 50MG CAPSULE as advised by your doctor during your menstrual
cycle. First, take one tablet a day for five days and then increase the dose.
Usually, there won’t be more than three courses of management.

Q: What does GOODOVA 50MG CAPSULE do?

A: GOODOVA 50MG CAPSULE is a combination of Clomiphene citrate that selectively
binds to oestrogen hormone receptors in the brain, ovary, endometrium and cervix
to increase the secretion of the luteinizing hormone as well as a
follicle-stimulating hormone for the release of a mature egg from the ovaries.
Melatonin improves egg quality by reducing the damage, which in turn leads to a
higher fertilization rate. This collective action is useful in managing female
infertility.

Q: Can this medicine be taken during pregnancy?

A: No, GOODOVA 50MG CAPSULE is not recommended for use in pregnant women or in
women who think they may be pregnant. You should take a pregnancy test before
taking the medicine. Consult your doctor for advice.

Q: How long does it take to get pregnant on GOODOVA 50MG CAPSULE?

A: Women under 35 years of age with the polycystic ovarian syndrome (PCOS)
should have about a 15% chance of pregnancy per month with GOODOVA 50MG CAPSULE
(for about 3–4 months) if they start to ovulate after taking the medicine
(assuming the sperm and fallopian tubes are normal).

Useful Diagnostic Tests

• Liver function test
• Serum triglyceride level
• Serum electrolyte level
• Urine examination