Flutrol 250 Inhaler 1's

Introduction About FLUTROL 250 INHALER

FLUTROL 250 INHALER is a combination of Fluticasone and Salmeterol which belongs
to the group of medicines called Corticosteroids and Bronchodilators
respectively. It is used to manage asthma and chronic obstructive pulmonary
disease (COPD). It also helps in reducing the flare-ups of COPD symptoms.

Asthma is a long-term respiratory disease in which your airways become inflamed,
swollen and narrowed. It also causes excessive mucous secretion in the airways
which makes it difficult for the air to pass through, leading to unpleasant
symptoms like wheezing, difficulty in breathing, chest pain and/or cough.

COPD is a lung disease characterized by chronic lung inflammation and obstructed
air flow within the airways. It causes wheezing, breathing difficulties, cough
with mucus production and chest pain.

Use FLUTROL 250 INHALER every day until your doctor tells you to stop. It is
meant for inhalation use only, and therefore do not the swallow the medicine. Do
not stop using this medicine once your symptoms subside without consulting your
doctor. It is suitable for use both in adults and in adolescents (aged 12 years
or above).

FLUTROL 250 INHALER should not be used to relieve a sudden asthma attack (such
as sudden breathing problems). Instead contact your doctor or use a fast-acting
‘rescue’ inhaler containing salbutamol to subside the symptoms.

Before using FLUTROL 250 INHALER inform your doctor if you have any lung
infections, liver problems or heart problems. You must also inform your doctor
if you have diabetes, hypertension, fits, overactive thyroid functions,
osteoporosis, adrenal gland problems or a weak immune system as a precaution.

FLUTROL 250 INHALER should be used in pregnant and breastfeeding women only if
it is considered necessary by the physician. The most common side effects of
using FLUTROL 250 INHALER are headache, cold, oral thrush or oral sores, throat
irritation, hoarse voice, muscle pain and joint pain. Contact your doctor if any
of these side effect worsens.

Uses Of FLUTROL 250 INHALER

It is used to manage, manage the symptoms of:

• Asthma
• Chronic Obstructive Pulmonary Disease (COPD)

How FLUTROL 250 INHALER Works

FLUTROL 250 INHALER is a combination of two medicines namely, fluticasone and
salbutamol. Fluticasone is an inhalation corticosteroid. It blocks the release
of certain chemical messengers in the airways (such as prostaglandins,
leukotrienes) that cause inflammation and swelling.

Salmeterol is a bronchodilator. It relaxes the smooth muscles of the airways and
widens them. Collectively, they reduce airway inflammation, allows the air to
pass through more freely and makes breathing easier.

How to use FLUTROL 250 INHALER

Use FLUTROL 250 INHALER medicine every day until your doctor tells you to stop.
It is meant for inhalation only. Inhale the medicine only through your mouth
into the lungs and not via nose.

Follow the instruction given in the enclosed leaflet.

• prime the device by releasing two puffs of the medicine into the air
• place the mouthpiece in your mouth between your teeth and ensure completely closure
• breathe in slowly and deeply using your mouth through the mouthpiece while simultaneously pressing the top of the c
• remove the device from your mouth and hold your breath for about 10 seconds or for as long as is comfortable
• wait about 30 seconds between taking each puff of medicine
• after inhalation, wipe the mouthpiece with a dry tissue and close the device after use
• once inhalation is over, rinse your mouth with water and spit it out or brush your teeth

Your doctor will decide the correct dose, duration and number of puffs for you
depending upon your age, body weight and disease condition.

Do not start using this medicine unless your doctor or health care provider has
taught you how to use and you understand how to use it correctly. If you find it
difficult to use this device, your doctor may recommend you a suitable spacer
device.

Do not stop taking this medicine abruptly or reduce the dose without consulting
your doctor, as it could make your breathing even worse.

Side Effects Of FLUTROL 250 INHALER

Common

• headache
• common cold
• thrush in the mouth or throat (a yeast infection that causes sore, creamy-yellow, raised patches)
• sore tongue, hoarse voice, throat irritation
• muscle pain or cramps
• joint pain and swelling
• bruising and fractures
• inflammation of sinuses
• signs of low levels of potassium in blood (such as an uneven heartbeat, muscle weakness or cramps)

Uncommon

• diabetes (increased blood sugar levels)
• cataract (cloudy eyes)
• unusually fast or uneven heartbeat, tremor (feeling shaky)
• chest pain
• feeling worried, disturbance in sleep
• allergic skin rash

Rare

• slowing of growth in adolescents, bone thinning, glaucoma, weight gain
• Cushing’s Syndrome (a disorder caused due to release of high levels of cortisol)
• changes in behavior (such as being unusually active and irritable)
• fungal infection in the esophagus which causes difficulties in swallowing

Stop using FLUTROL 250 INHALER and contact your doctor immediately if you
experience any of the following side effects:

• severe allergic reactions (such as sudden wheezing, cough, shortness of breath, skin rash, itching, swelling of the face, lips, tongue, or throat, breathing difficulties, sudden fast heartbeat which can cause fainting, light-headedness, collapse or even loss of consciousness)
• sign of pneumonia (a lung infection accomp

How To Manage Side Effects

Headache:

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a
pain-relieving balm on the head if required. Do not consume too much of alcohol.
Consult your doctor if the symptom did not improve.

Throat irritation:

Gargle your throat with salt water twice a day. Always try to drink warm water.
Avoid chilled, cooled, or sweetened food items or beverages. Drinking turmeric
milk or ginger tea mixed with honey and pepper powder can ease the soreness.
Consult your doctor if the symptom did not improve.

Muscle pain or cramps:

Rub a pain-relieving balm or place a heat pack on the affected area for some
time, as it could ease the pain. Do not move the affected area frequently. Try
to do some simple movements every day which would improve blood circulation and
reduce further incidence of muscle pain. Try to eat a well-balanced protein rich
diet, so that it can help to repair and rebuild the damaged muscle. Consult your
doctor if the symptom did not improve.

Joint pain:

Rub a pain-relieving balm or place a heat pack on the affected area for some
time, as it could ease the pain. Do not move the affected area frequently.
Consume calcium and vitamin supplements regularly, particularly if you are
elderly. Consult your doctor if the symptom did not improve.

Allergic skin rash:

Avoid hot showers because hot water can irritate your skin further. Do not
scratch the affected area. Use protective clothing when going outdoors.
Regularly moisturize your skin. Consult your doctor if the symptom did not
improve.

Warning & Precautions

!### Pregnancy

FLUTROL 250 INHALER should be used in pregnant women only if it is considered
necessary by the doctor. Your doctor may prescribe this medicine after
outweighing the risk and benefits to you and your baby. Therefore, inform your
doctor before using it.

!### Breastfeeding

FLUTROL 250 INHALER should be used in breastfeeding women only if it is
considered necessary by the doctor. Therefore, consult your doctor for advice
before using it.

!### Driving and Using Machines

Do not drive or operate any heavy tools or machines if your ability is affected
by FLUTROL 250 INHALER.

!### Liver

FLUTROL 250 INHALER should be taken with caution in patients with liver
diseases. Therefore, consult your doctor before using it.

!### Allergy

Do not use FLUTROL 250 INHALER if you are allergic to Salmeterol or Fluticasone.

!### Lungs

FLUTROL 250 INHALER should be taken with caution among patients who have or
previously had any Tuberculosis or any other lung infections. Therefore, consult
your doctor before using it.

!### Heart Disease

FLUTROL 250 INHALER should be taken with caution in patients with heart diseases
(such as irregular or fast heartbeat). Therefore, consult your doctor before
using it.

Others

FLUTROL 250 INHALER is not recommended for use in patients having:

• status asthmaticus (respiratory failure)
• acute asthma attacks

Before using FLUTROL 250 INHALER, inform your physician if you:

• have an over-active thyroid gland
• have diabetes
• have high blood pressure
• have hypokalemia (low levels of potassium in blood)
• have fits (seizure)
• have osteoporosis (weak bones)
• have a weak immune system
• have or had eye problems (such as glaucoma, increased pressure in the eyes, cataracts)
• have viral, bacterial or fungal infections (Ex. measles, chickenpox)
• have glucose intolerance
• have problems in adrenal gland (Ex. adrenal insufficiency)
• met with any major trauma (accidents) or undergone a surgery

Use in pediatrics:

FLUTROL 250 INHALER is not recommended for use in children younger than 12 years
of age. Kindly consult your doctor before using it.

Use in geriatrics:

FLUTROL 250 INHALER should be taken with caution in elderly patients (aged 65
years or above). Therefore, consult your doctor before using it. Proper dose
adjustments and careful monitoring are required in such patients.

Interactions

A. Drug-Drug interactions:

Before using FLUTROL 250 INHALER, inform your physician if you are taking any of
the following medicines such as:

• other beta-blockers (used to manage high blood pressure or other heart conditions) Ex. atenolol, propranolol and sotalol
• medicines used to manage fungal infection (such as ketoconazole and itraconazole)
• medicines used to manage HIV infection (Ex. ritonavir, atazanavir, indinavir, nelfinavir, saquinavir or cobicistat)
• clarithromycin, erythromycin (used to manage bacterial infections)
• other corticosteroids (taken orally or via injections to manage pain or inflammation) Ex. dexamethasone
• potassium-sparging diuretics (used to manage high blood pressure by increasing urine output) Ex. spironolactone, acetazolamide
• other medicines that can cause bronchodilation (such as salbutamol, formoterol)
• xanthine medicines (used to manage asthma) Ex. theophylline and aminophylline
• nefazodone (used to manage depression)
• medicines used to manage depression such as (rasagiline, selegiline, phenelzine, amitriptyline, nortriptyline, doxepin, imipramine, desipramine)

Overdosage:

If you or anyone else accidentally inhaled excessive amount of this medicine,
contact your doctor immediately or go to the hospital straight away. Symptoms of
overdosage might include shortness of breath, chest pain, fast heartbeat,
feeling shaky, dizziness, headache, muscle weakness and joint pain.

Synopsis

Drug	:	Fluticasone, Salmeterol
Pharmacological Category	:	Corticosteroids, Beta-1 receptor agonists
Therapeutic Indication	:	Asthma, COPD
Dosage Forms	:	Autohaler, Blisters, Capsule, Inhalation capsule, Octacaps, Respicaps, Rotacaps, Trans caps, Nexcaps, Accuhaler, Inhaler, Ciphaler, Multihaler

More Information

• Keep FLUTROL 250 INHALER out of reach of children
• Store FLUTROL 250 INHALER at room temperature

FAQs About FLUTROL 250 INHALER

What is the use of FLUTROL 250 INHALER?

FLUTROL 250 INHALER is used to manage asthma and chronic obstructive pulmonary
disease (COPD). It also helps in reducing flare-ups of COPD symptoms.

How FLUTROL 250 INHALER works in my body?

FLUTROL 250 INHALER relaxes the smooth muscles of the airways and widens them.
It also reduces the inflammation of airway tract. Therefore, it allows the air
to pass through more freely and makes breathing easier.

Can FLUTROL 250 INHALER be used on an asthma attack?

FLUTROL 250 INHALER is only used to manage or manage the symptoms of asthma and
COPD (such as breathlessness or wheezing). If your asthma or breathing gets
worse suddenly, contact your doctor immediately or go to the straight away to
avoid further exacerbation of the attack. Meanwhile use a fast-acting rescue
inhaler containing salbutamol along with this medicine.

Is FLUTROL 250 INHALER safe?

FLUTROL 250 INHALER is considered safe at doses prescribed by the physician.

What are the side effects of using FLUTROL 250 INHALER?

The most common side effects of using FLUTROL 250 INHALER are headache, cold,
oral thrush or oral sores, throat irritation, hoarse voice, muscle pain and
joint pain. Contact your doctor if any of these side effect worsens.

Can I stop using FLUTROL 250 INHALER once my symptoms subside?

No. Use FLUTROL 250 INHALER every day until your doctor tells you to stop. Do
not stop taking this medicine abruptly or reduce the dose without consulting
your doctor, as it could make your breathing even worse. Your doctor will access
your disease condition regularly and will increase or decrease the dose
accordingly.

Will FLUTROL 250 INHALER more effective if taken at higher doses?

Always consume the dose prescribed for you by your physician. Your doctor will
decide the correct dose and duration of therapy for you depending upon your age,
body weight and severity of the disease. Do not take a higher dose of this
medicine without consulting your doctor as it could lead to unwanted side
effects. It your symptoms are not relieved by the prescribed dose, consult your
doctor so that he might adjust the dose according to your health condition or
can suggest an alternative therapy.

I’m pregnant. Can I use FLUTROL 250 INHALER?

FLUTROL 250 INHALER should be used in pregnant women only if it is considered
necessary by the physician. Your doctor will prescribe you with FLUTROL 250
INHALER after evaluating the risks and benefits of the therapy.

Can FLUTROL 250 INHALER be used in children?

FLUTROL 250 INHALER is considered safe for use in children and adolescents aged
12 years or above. However, it is not recommended for use in children younger
than 12 years due to lack of safety data. Kindly consult your doctor before
taking.

How long will it take for FLUTROL 250 INHALER to relieve the symptoms and how
long the effects can last?

Generally, FLUTROL 250 INHALER takes about 10-15 minutes to relieve the symptoms
of asthma or COPD. However, the onset of action slightly differs from person to
person based upon their disease condition. The effects of FLUTROL 250 INHALER
can last for 12-18 hours, because salmeterol present in this medicine is
considered as a longer-acting beta-1 adrenergic agonist.

Can FLUTROL 250 INHALER cause infection in the mouth?

Yes. FLUTROL 250 INHALERmay causefungal infections of the mouth (oral thrush).
To avoid this, make sure to rinse your mouth with water after inhaling the
medicine. However, if an infection develops, consult your doctor.

What happens when you forget to use FLUTROL 250 INHALER?

If you forget to use FLUTROL 250 INHALER, use it as soon as you remember.
However, if it's time for the next dose, skip the missed dose and take the next
dose. Do not use a double dose to compensate the missed dose.

Can FLUTROL 250 INHALER be used if you have an infection?

Inform your doctor if you have any bacterial, fungal, or viral infection before
using FLUTROL 250 INHALER. Your doctor will evaluate your existing health
condition and advise changes in management accordingly. Also, inform your doctor
if have exposure to an infectious environment or with a person with infectious
diseases, as FLUTROL 250 INHALER may mask your symptoms of the infection.

Useful Diagnostic Tests

• Absolute eosinophil count
• Complete blood count