Duron 200mg Tablet 10'S

Introduction About DURON 200MG TABLET

DURON 200MG TABLET contains Amiodarone which belongs to the group of medicines
called Antiarrhythmics. It is used to manage uneven or fast heartbeats (like
atrial flutter or atrial fibrillation), fast heartbeats which may happen
suddenly and may be uneven only when other medicines either have not worked or
cannot be used. It also manages Wolff-Parkinson-White Syndrome (unusually fast
heartbeats). Your doctor might want you to keep out of direct sunlight while
taking DURON 200MG TABLET and for a few months after you have finished taking
it.

Avoid consum
200MG TABLET. DURON 200MG TABLET is not recommended for use if you have signs of
an allergic reaction including (a rash, swallowing or breathing difficulties,
swelling of your lips, face, throat or tongue).

It is also not recommended to use if you have slower than usual heartbeat
(called ‘sinus bradycardia’) or an illness called sino-atrial heart block, other
problems with your heartbeat without a pacemaker fitted, are going to have a
heart transplantation or have thyroid problems.

Before taking DURON 200MG TABLET, inform your doctor if you have heart failure,
liver, lung problems or asthma, eyesight problems (o
have any surgery, have a pacemaker or implantable cardioverter defibrillator
(ICD). Also inform your doctor if you have intolerance to certain sugars,
blistering or peeling of the skin around the lips, eyes, mouth, nose and
genitals, flu-like symptoms and fever (Stevens-Johnson syndrome), layers of the
skin peeling off to leave large areas of raw exposed skin over the body (Toxic
Epidermal Necrolysis).

DURON 200MG TABLET is not recommended for pregnant or breastfeeding women. It is
not recommended for use in children and adolescents below 18 years of age. DURON
200MG TABLET should be used with caution in elderly patients above 65 years of
age. The most common side effects of taking DURON 200MG TABLET are nausea,
vomiting, change in taste, constipation, sleeping problems. Consult your doctor
if any of the symptoms worsen.

Uses Of DURON 200MG TABLET

It is used to manage:

• sudden, fast or uneven heartbeats (atrial flutter or atrial fibrillation) when other medicines either have not worked or cannot be used
• Wolff-Parkinson-White Syndrome

How DURON 200MG TABLET Works

DURON 200MG TABLET works by blocking certain electrical signals and reducing the
excitability of cardiac tissues which manages the initiation and conduction of
any new impulses in the heart that cause irregular heartbeats, thus making your
heartbeat return to normal.

How to use DURON 200MG TABLET

Take DURON 200MG TABLET as advised by your physician. Swallow the medicine with
a glass of water. Do not crush or chew the medicine. Your doctor will decide the
correct dose and duration for you depending upon your age, body weight and
disease condition.

Side Effects Of DURON 200MG TABLET

Common

• nausea, vomiting, constipation, change in taste
• tanning more easily in the sun
• slightly slower heartbeat
• nightmares, sleep problems
• scaly and itchy rash
• reduced sex drive

Uncommon

• dry mouth

Rare

Stop taking DURON 200MG TABLET and consult your doctor immediately if you
experience any of the following side effects:

• allergic reaction (rash, swollen eyelids, face, lips, throat or tongue)
• Stevens-Johnson syndrome (blistering or peeling of the skin around the lips, eyes, mouth, nose and genitals, flu-like symptoms and fever)
• toxic epidermal necrolysis (severe blistering rash in which layers of the skin may peel off, feeling generally unwell, fever, chills and muscle pain)
• bullous dermatitis (fluid filled blisters on the skin)
• flu like symptoms and a rash on the face followed by an extended rash with a high temperature, enlarged lymph nodes (DRESS)
• yellowing of the skin or eyes (jaundice), feeling tired or sick, loss of appetite, stomach pain or high temperature. (signs of liver problems or damage)
• shortness of breath or difficulty breathing , tightness in the chest, coughing which will not go away, wheezing, weight loss and fever ( inflammation of your lungs)
• heartbeat becomes even more uneven or erratic (can lead to a heart attack)
• feeling numb or weak, tingling or burning feelings in any part of the body
• feeling extremely restless or agitated, weight loss, increased sweating and being unable to stand the heat (signs of hyper-thyroidism)
• unable to stand the cold, constipation and aching muscles (signs of hypo-thyroidism)
• trembling when you move your arms or legs
• blue or gray marks on parts of your skin exposed to sunlight
• muscle cramps, stiffness or spasm
• blurred eyesight or seeing a coloured halo in dazzling light

How To Manage Side Effects

Nausea and vomiting:

Stick to simple meals. Avoid eating oily or spicy foods. Drink more water.
Consult your doctor if symptoms don't show improvement.

Constipation:

Eat plenty of fiber rich foods such as fresh fruits, vegetables and cereals and
drink plenty of water. Exercise more regularly. Consult your doctor if symptoms
don't show improvement.

Rash:

Applying a cold compress, cool showers or damp cloth, cold water can bring
immediate relief to swelling and reduce itching. Consult your doctor if symptoms
don't show improvement.

Tanning:

Make sure you use high factor sun cream. Always wear a hat and clothes which
cover your arms and legs. Consult your doctor if symptoms don't show
improvement.

Warning & Precautions

!### Pregnancy

DURON 200MG TABLET is generally not recommended for use in pregnant women or
women planning to have a baby. Consult your doctor before taking DURON 200MG
TABLET.

!### Breastfeeding

DURON 200MG TABLET is generally not recommended for use in breastfeeding women
as it may pass through the breast milk. Consult your doctor before taking DURON
200MG TABLET.

!### Driving and Using Machines

Do not drive or operate any machines if you feel like your eyesight is blurry
after taking DURON 200MG TABLET.

!### Alcohol

Avoid consum
may increase the chances of liver problems.

!### Liver

DURON 200MG TABLET should be taken with caution in patients with liver disease.
Consult your doctor before taking DURON 200MG TABLET.

!### Allergy

Do not take DURON 200MG TABLET if you are allergic to Amiodarone, iodine or any
other ingredients of this medicine.

!### Lungs

DURON 200MG TABLET should be taken with caution in patients with asthma or other
lung disease. Consult your doctor before taking DURON 200MG TABLET.

!### Heart Disease

DURON 200MG TABLET is not recommended for use if you haveslower than usual
heartbeat (called ‘sinus bradycardia’) or an illness called sino-atrial heart
block, other problems with your heartbeat without a pacemaker fitted or are
going to have a heart transplantation.

DURON 200MG TABLET should be taken with caution in patients with heart failure
or if you have a pacemaker or implantable cardioverter defibrillator (ICD).
Consult your doctor before taking DURON 200MG TABLET.

Others

DURON 200MG TABLET is not recommended for use if you:

• have signs of an allergic reaction include (a rash, swallowing or breathing difficulties, swelling of your lips, face, throat or tongue)
• history of thyroid problems

Before taking DURON 200MG TABLET, inform your doctor if you:

• have any issues with your eyesight (o
• are about to have any surgery
• have Stevens-Johnson syndrome (blistering or peeling of the skin around the lips, eyes, mouth, nose and genitals, flu-like symptoms and fever)
• have toxic epidermal necrolysis (severe blistering rash in which layers of the skin may peel off, feeling generally unwell, fever, chills and muscle pain)
• intolerance to certain sugars

Use in pediatrics:

DURON 200MG TABLET is generally not recommended for use in children and
adolescents below 18 years of age. Consult your doctor before taking it.

Use in geriatrics:

DURON 200MG TABLET should be used with caution in elderly patients above 65
years of age. Dose will be adjusted by your doctor. Consult your doctor before
taking DURON 200MG TABLET.

Interactions

A. Drug - Drug interactions:

Before taking DURON 200MG TABLET, inform your doctor if you are taking any of
the following medicine:

• other medicines used to manage uneven heartbeats (Ex. sotalol, quinidine, procainamide, disopyramide, flecainide or bretylium)
• medicines used to manage infections (Ex. intra-venous erythromycin, co-trimoxazole, moxifloxacin, pentamidine, clarithromycin, ciprofloxacin, ofloxacin or levofloxacin)
• medicines used to manage schizophrenia (Ex. chlorpromazine, fluphenazine, thioridazine, pimozide, haloperidol, sertindole or amisulpride)
• medicines used to manage other mental illnesses (Ex. lithium, doxepin, maprotiline or amitriptyline)
• medicines used to manage malaria (Ex. quinine, mefloquine, chloroquine or halofantrine)
• medicines used to manage hay fever, rashes or other allergies (Ex. terfenadine, astemizole or mizolastine)
• medicines used to manage hepatitis C (Ex. sofosbuvir, daclatasvir, simeprevir or ledispasvir)
• medicine used to manage heart problems (such as high blood pressure, chest pain or high cholesterol) (Ex. Propranolol, diltiazem, verapamil, furosemide, simvastatin, atorvastatin or digitalis)
• medicines used to manage constipation (Ex. bisacodyl or senna)
• medicines for high cholesterol (statins) (Ex. simvastatin or atorvastatin)
• medicines used to manage fungal infection (Ex. Amphotericin IV)
• medicines used to manage inflammation (Ex. hydrocortisone, betamethasone or prednisolone)
• water tablets (diuretics like chlorthalidone) to reduce blood pressure
• medicines used during surgery (Ex. lidocaine, midazolam or high dose oxygen)
• medicines used to test some hormone problems (Ex. Tetracosactide)
• medicines used to manage rejection of transplants (Ex. Ciclosporin, tacrolimus and sirolimus)
• medicines used to manage impotence (Ex. sildenafil, tadalafil or vardenafil)
• medicines used to manage pain (Ex. fentanyl)
• medicines used for migraines (Ex. ergotamine)
• medicines used to manage gout (Ex. Colchicine)
• medicines used to stop your blood from clotting (Ex. Warfarin, dabigatran)

B. Drug - Food interaction:

Avoid drinking grapefruit juice while taking DURON 200MG TABLET as it may
increase the risk of side effects.

Overdosage:

If you or anyone else accidentally takes too much DURON 200MG TABLET, consult
your doctor immediately or visit the nearby hospital. Symptoms of overdose are
feeling dizzy, faint or tired, confusion, slow heartbeat, damage to the liver or
nausea.

Synopsis

Drug	:	Amiodarone
Pharmacological Category	:	Antiarrhythmic
Therapeutic Indication	:	Arrhythmias, Wolff-Parkinson-White Syndrome
Dosage Forms	:	Tablet, Injection

More Information

• Keep DURON 200MG TABLET out of reach of children
• Do not store above 25°C

FAQs About DURON 200MG TABLET

What is DURON 200MG TABLET used for?

DURON 200MG TABLET is used to manage uneven or fast heartbeats (like atrial
flutter or atrial fibrillation), fast heartbeats which may happen suddenly and
may be uneven only when other medicines either have not worked or cannot be
used. It also manages Wolff-Parkinson-White Syndrome (unusually fast
heartbeats).

How does DURON 200MG TABLET work?

DURON 200MG TABLET works by blocking certain electrical signals and reducing the
excitability of cardiac tissues which manages the initiation and conduction of
any new impulses in the heart that cause irregular heartbeats, thus making your
heartbeat return to normal.

CanDURON 200MG TABLET make my skin sensitive to the sun?

Yes. your skin will become much more sensitive to the sun after taking DURON
200MG TABLET and may burn, tingle or severely blister. Do not expose yourself to
direct sunlight while taking this medicine and for a few months after you have
finished taking it. Use high factor sun cream without fail. Always wear a hat
and clothes which cover your whole body.

What should I avoid while taking DURON 200MG TABLET?

Avoid drinking grapefruit juice while taking DURON 200MG TABLET as it may
increase the risk of side effects. Avoid consum
management with DURON 200MG TABLET, as it may increase the chances of liver
problems.

Can DURON 200MG TABLET cause stomach problems?

Yes, DURON 200MG TABLET can cause nausea, vomiting, constipation or diarrhea as
a common side effect. Consult your doctor if symptoms worsens or does not show
any improvement.

Useful Diagnostic Tests

• Liver Function Test (LFT)
• Thyroid Function Test (TFT)
• Complete Blood Count (CBC)
• Chest X-Ray
• Electrocardiogram (ECG)
• Eye tests
• Blood pressure test