DECAMYCIN Injection 10ml

Introduction About DECAMYCIN INJECTION

DECAMYCIN INJECTION contains Dexamethasone which belongs to the group of
medicines called Corticosteroids. It is used to manage problematic conditions of
the adrenal glands (such as adrenal insufficiency, congenital adrenal
hyperplasia and nonsuppurative thyroiditis).

It can also be used to manage various inflammatory auto-immune disease
conditions affecting the bones and joints (Ex. rheumatoid arthritis, ankylosing
spondylitis), skin and collagen (Ex. Stevens-Johnson syndrome, psoriasis), eyes
(Ex. o
pneumonitis, tuberculosis), blood and lymph (Ex. leukaemia, anemia,
thrombocytopenia, blood cancer, lymph cancer, sarcoidosis), bowel and gut (Ex.
Crohn’s disease and ulcerative colitis), brain (Ex. tuberculous meningitis,
cerebral edema associated with brain tumor, increased pressure within the skull)
and heart (inflammation of heart membranes).

It is also indicated in the management of drug induced hypersensitivity
reactions and in other allergic reactions (such as atopic dermatitis, allergic
conjunctivitis and allergic rhinitis). It also corrects calcium levels among
cancer patients and increases urine output or reduces protein loss via urine
among patients having kidney problems (such as nephrotic syndrome).

Before receiving DECAMYCIN INJECTION inform your doctor if you any liver, kidney
or heart problems. You must also inform your doctor if you have diabetes,
hypertension, glaucoma, epilepsy, underactive thyroid, muscle problems,
osteoporosis, stomach problems, tuberculosis, depression, m
mental problems as a precaution.

DECAMYCIN INJECTION is not recommended for use in patients with serious
unmanageed infections in the body or bone problems. It is also not suitable for
use in pregnant or breastfeeding women.

The most common side effects of receiving DECAMYCIN INJECTION are headache,
dizziness, acne, stomach discomfort, slow wound healing, skin thinning, high
blood pressure, fluid retention, swelling and weight gain of the body and face,
high blood sugar levels, muscle weakness, bone thinning and irregular menstrual
periods. Consult your doctor if any of these side effect worsens.

Uses Of DECAMYCIN INJECTION

It is used to manage the following disease conditions:

• adrenal insufficiency and its associated conditions
• bone and joint problems (Ex. rheumatoid arthritis, ankylosing spondylitis)
• skin and collagen disorders (Ex. Stevens-Johnson syndrome, psoriasis)
• eye problems (Ex. o
• respiratory tract diseases (Ex. asthma, tuberculosis, pneumonitis)
• blood cancer (leukemia), lymph cancer (lymphoma)
• anemia (low RBC count in blood), thrombocytopenia (low platelet count in blood)
• problems of bowel and gut (Ex. Crohn’s disease and ulcerative colitis)
• brain problems (Ex. tuberculous meningitis, cerebral edema)
• increased intracr
• heart inflammation (Ex. endocarditis)
• drug induced hypersensitivity reactions
• allergic reactions (such as atopic dermatitis, allergic conjunctivitis and allergic rhinitis)
• high blood calcium levels caused due to cancer management
• protein loss via urine due to kidney problems

How DECAMYCIN INJECTION Works

DECAMYCIN INJECTION is a steroid medicine with anti-inflammatory and immune
suppressant properties. It boosts your body with sufficient corticosteroid
levels (cortisol, aldosterone) during deficient conditions and helps your body
to function properly.

It also reduces the release of certain chemicals (prostaglandins) in the body
that causes inflammation, pain, irritation and swelling. As a result, it reduces
allergic and inflammatory conditions in the body.

How to use DECAMYCIN INJECTION

DECAMYCIN INJECTION will be given to you only by a doctor or a nurse into the
vein, muscle, joints or tendons depending upon the site of inflammation.

Your doctor will decide the correct dose and duration of therapy for you
depending upon your age, body weight and disease condition.

Side Effects Of DECAMYCIN INJECTION

Common

• headache, dizziness
• spinning sensation, increased sweating
• acne, skin rash, bruising
• nausea, stomach pain or discomfort, increased appetite
• changes in vision, feeling weak or tired, slow wound healing
• skin thinning
• fits
• difficulty in swallowing, sore throat
• high blood pressure, fluid retention
• swelling and weight gain of the body and face
• high blood sugar levels, with excessive thirst
• muscle weakness and wasting
• bone thinning with an increased risk of fractures
• raised pressure in the eye, cataracts
• irregular or lack of menstrual periods
• increased infections

Contact your doctor immediately if you experience any of the following side
effects:

• signs of allergic reaction (such as skin rash, itching, blistering and peeling of the skin, swelling of the face, lips, mouth, throat which may lead to breathing difficulties)
• severe skin rashes with blistering and peeling of skin
• feeling depressed, suicidal thoughts, m
• anxiety, sleeping problems, problems in thinking, confusion, memory loss
• hallucinations, strange thoughts, behavioural changes
• signs of pheochromocytoma crisis (headaches, sweating, palpitations and hypertension)
• signs of adrenal suppression (such as swelling and weight gain around the trunk, excessive hair growth in women, muscle weakness and wasting, irregular or missing periods, stunted growth in children, purple stretch marks on body skin, changes in the levels of protein and calcium in your body)
• signs of bleeding in the gut (such as stomach pain which radiates until your back, bleeding from the anus, black or blood-stained stools, blood in vomit)
• increased infections causing fever or a general feeling of being unwell
• signs of flare up of a previous tuberculosis infection (such as coughing blood or pain in the chest)
• signs of pancreatitis (inflammation of pancreas causing severe stomach pain and vomiting)
• signs of blood clot in lungs (such as sharp chest pain, shortness of breath, coughing up blood)
• signs of increased pressure within the skull (such as severe headaches with vomiting, lack of energy and drowsiness) usually occurs once therapy is stopped

How To Manage Side Effects

!### Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or
machines completely while you are feeling dizzy. Do not consume excessive
alcohol, as it could aggravate your dizziness. Consult your doctor if your
dizziness worsens.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Do not consume excessive alcohol, as it could aggravate your
headache. Consult your doctor if your headache worsens.

!### Nausea And Vomiting

Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if
your nausea worsens.

Warning & Precautions

!### Pregnancy

ContraindicatedDECAMYCIN INJECTION is not recommended for use in pregnant women as it may cause
serious harm to the growing baby. Therefore, consult your doctor before
receiving it.

!### Breastfeeding

ContraindicatedDECAMYCIN INJECTION is not recommended for use in breastfeeding women as it may
pass through the breast milk and affect the nursing infant. Therefore, consult
your doctor before receiving it.

!### Driving and Using Machines

Use with CautionDECAMYCIN INJECTION is unlikely to affect your ability to drive or handle any
heavy tools or machines.

!### Alcohol

Consult your doctorAvoid consum
you feel drowsier.

!### Kidney

Use with CautionDECAMYCIN INJECTION should be used with caution in patients with kidney
diseases. Therefore, consult your doctor before receiving it.

!### Liver

Use with CautionDECAMYCIN INJECTION should be used with caution in patients with liver diseases.
Therefore, consult your doctor before receiving it.

!### Allergy

ContraindicatedTalk to your doctor before receiving DECAMYCIN INJECTION if you are allergic to
Dexamethasone.

!### Heart Disease

Use with CautionDECAMYCIN INJECTION should be used with caution in patients with heart problems
(such as recent heart attack or heart failure). Therefore, consult your doctor
before receiving it.

!### Use In Pediatrics

Monitoring requiredDECAMYCIN INJECTION should be used in children and adolescents (aged below 18
years) only if prescribed by the physician. Therefore, consult your doctor for
advice before receiving it.

!### Use In Geriatrics

Use with CautionDECAMYCIN INJECTION should be used with caution in elderly patients (aged 65
years or above). Therefore, consult your doctor before receiving it.

Others

DECAMYCIN INJECTION is not recommended for use if you:

• have any serious infection that affects the whole body
• have any bone or joint problems
• have infections in the joints
• are about to get vaccinated (live-virus vaccine)

Before receiving DECAMYCIN INJECTION, inform your doctor if you:

• currently have or previously had depression, bipolar disorder or any other mental illnesses
• have a family history of mental problems
• have diabetes or a family history of diabetes
• have fits
• have or have a family history of glaucoma
• have viral or fungal infections of the eyes
• have hypertension (high blood pressure)
• have underactive thyroid gland (hypothyroidism)
• have malaria affecting the brain
• have or had been in contact with someone who has chickenpox, measles or shingles
• have any muscle problems (Ex. myasthenia gravis)
• have osteoporosis (brittle bones)
• have pheochromocytoma (a rare tumor of the adrenal glands)
• have stomach ulcer or other serious stomach or intestinal problems
• have or had tuberculosis
• have symptoms of tumour lysis syndrome (such as muscle cramping, muscle weakness, confusion, visual loss or disturbances and shortness of breath)
• are scheduled for any upcoming surgery (including dental surgery)
• have any parasitic infection
• have Cushing’s disease
• have brain injury due to trauma
• have had stroke or any unusual stress

Interactions

A. Drug-Drug interactions:

Before receiving DECAMYCIN INJECTION, inform your doctor if you are taking any
of the following medicines such as:

• aminoglutethimide or cyclophosphamide (used for managing cancer)
• anticoagulants (used for blood thinning) such as acenocoumarol, phenindione and warfarin
• medicines used to manage bacterial infections (Ex. isoniazid, erythromycin, clarithromycin and troleandomycin)
• medicines used to manage diabetes (Ex. metformin, glipizide)
• non-steroidal anti-inflammatory medicines (used for fever and pain relief) such as aspirin, ibuprofen
• medicines used to manage epilepsy (such as carbamazepine, phenytoin and primidone)
• ephedrine (used for cough)
• medicines used to manage HIV infections such as ritonavir, cobicistat
• medicines used to manage fungal infection (such as ketoconazole, amphotericin B, itraconazole)
• diuretics (used to manage edema and hypertension) Ex. furosemide, chlorothiazide, hydrochlorothiazide
• rifampicin and rifabutin (used to manage tuberculosis)
• carbenoxolone (used to manage mouth ulcer)
• anti-cholinergic medicines used to manage myasthenia gravis (such as distigmine and neostigmine)
• acetazolamide (a medicine used to manage glaucoma or edema)

Overdosage:

DECAMYCIN INJECTION will be administered to you only by a doctor or a nurse in a
hospital and so it is unlikely to receive an overdose. However, consult your
doctor or nurse if you experience any unusual symptoms.

Synopsis

Drug	:	Dexamethasone
Pharmacological Category	:	Corticosteroids
Therapeutic Indication	:	Adrenal insufficiency, Auto Immune Disease, Allergic reactions, Proteinuria
Dosage Forms	:	Tablet, Injection, Eye drops, Eye/Ear Drops

More Information

Storage

• Keep DECAMYCIN INJECTION out of reach of children
• Store DECAMYCIN INJECTION at room temperature or in a refrigerator (between 2-8°C) based on the instructions mentioned in the product label

FAQs About DECAMYCIN INJECTION

Q: What is DECAMYCIN INJECTION used for?

A: DECAMYCIN INJECTION is a corticosteroid medicine used to manage adrenal
insufficiency. It can also be used to manage drug induced hypersensitivity
reactions, allergic reactions and various inflammatory auto-immune disease
conditions affecting the skin, collagen, bones and joints, brain, gut, eyes etc.
It also increases urine output and manages protein loss via urine among patients
having kidney problems.

Q: How DECAMYCIN INJECTION is administered?

A: DECAMYCIN INJECTION will be given to you only by a doctor or a nurse into the
vein, muscle, joints or tendons depending upon the site of inflammation.

Q: Is DECAMYCIN INJECTION a steroid?

A: Yes. DECAMYCIN INJECTION is corticosteroid used to manage problems of adrenal
gland and various allergic, hypersensitivity and inflammatory autoimmune disease
conditions.

Q: What are the most common side effects of DECAMYCIN INJECTION?

A: The most common side effects of receiving DECAMYCIN INJECTION are headache,
dizziness, acne, stomach discomfort, slow wound healing, skin thinning, high
blood pressure, fluid retention, swelling and weight gain of the body and face,
high blood sugar levels, muscle weakness, bone thinning and irregular menstrual
periods. Consult your doctor if any of these side effect worsens.

Q: Can DECAMYCIN INJECTION make you feel high?

A: Yes. DECAMYCIN INJECTION may make you feel high. Such symptoms may disappear
once the therapy has been stopped. However, consult your doctor if it bothers
you.

Q: How does DECAMYCIN INJECTION works?

A: DECAMYCIN INJECTION boosts your body with sufficient corticosteroid levels
and helps your body to function properly. It also reduces the release of certain
chemicals in the body that causes inflammation. Therefore, it reduces allergic
and inflammatory responses in the body.

Q: How long will it take for DECAMYCIN INJECTION to control my disease?

A: The time taken by DECAMYCIN INJECTION to control the disease may vary from
person-to-person depending upon the dose of dexamethasone and disease severity.

Q: Is DECAMYCIN INJECTION safe to use in diabetic patients?

A: DECAMYCIN INJECTION may alter the blood sugar levels in your body. Therefore,
it is necessary to inform your doctor if you have diabetes before receiving
DECAMYCIN INJECTION as a precaution.

Q: Who should not take DECAMYCIN INJECTION?

A: DECAMYCIN INJECTION is not recommended for use in patients with serious viral
fungal infections. It is also not suitable for use in patients having bone
problems, bone infection and mental illnesses or a family history of the same.

Q: Can I take a higher dose of DECAMYCIN INJECTION?

A: No. It is not safe to take a higher dose of DECAMYCIN INJECTION without
consulting your doctor. If the prescribed dose is less effective for you, kindly
consult your doctor for a suitable high dose or for an alternative therapy.

Q: Can I take DECAMYCIN INJECTION daily?

A: Your doctor will evaluate your health condition and suggests whether can you
take DECAMYCIN INJECTION every day or not.

Q: Can I stop receiving DECAMYCIN INJECTION once by pain reduces?

A: Take DECAMYCIN INJECTION for the stipulated duration recommended by your
doctor to achieve maximum results. Do not stop receiving DECAMYCIN INJECTION or
reduce the dose without consulting your doctor, as sudden cessation of the
therapy may lead to unpleasant withdrawal symptoms such as skin itchiness,
fever, headache, muscle pain, joint pain, runny nose, tiredness or weight loss,
especially if you are receiving higher dose of dexamethasone.

Q: Can DECAMYCIN INJECTION be used in children?

A: DECAMYCIN INJECTION should be used in children and adolescents (aged below 18
years) only if prescribed by the physician. Therefore, consult your doctor for
advice before receiving it.

Q: Can DECAMYCIN INJECTION be used in pregnant women?

A: DECAMYCIN INJECTION is not recommended for use in pregnant women as it may
cause serious harm to the growing baby. Therefore, consult your doctor before
receiving it.