Cytosar 100mg Injection 5ml

Introduction About CYTOSAR 100MG INJECTION

CYTOSAR 100MG INJECTION contains Cytarabine which belongs to the group of
medicines called Anticancer agents. It is used for certain types of blood cancer
and lymph cancer (Ex. acute myeloid leukemia, erythroleukemia, meningeal
leukemia, acute non-lymphoblastic/lymphoblastic leukemia, acute lymphocytic
leukemia, chronic myeloid leukemia, non-Hodgkin’s lymphoma).

Before receiving CYTOSAR 100MG INJECTION, inform your doctor if you have any
liver or kidney problems. You must also inform your doctor if you have low RBC,
WBC and platelet counts in blood, or currently taking radiotherapy as a
precaution. Avoid consum
medicine. CYTOSAR 100MG INJECTION is not recommended for use in pregnant or
breastfeeding women. Both men and women of childbearing potential must use a
suitable contrace
medicine and until 6 months after the last dose.

The most common side effects of receiving CYTOSAR 100MG INJECTION are low RBC,
WBC and platelet counts leading to anemia, increased infections and bleeding
tendency and loss of appetite, abnormal eye movements, eye pain, redness and
inflammation, nausea, vomiting, mouth ulcers, sore tongue, skin rashes, hair
loss and inflammation at the injection site. Consult your doctor if any of these
above side effect worsens.

Uses Of CYTOSAR 100MG INJECTION

• Used for certain types of blood cancer and lymph cancer

How CYTOSAR 100MG INJECTION Works

CYTOSAR 100MG INJECTION works by damaging the cellular genetic material (DNA).
This interferes with the functions of DNA and works against cancer cells from
multiplying. As a result, it manages abnormal cell division within the body,
slows down the growth of cancer cells and helps the bone marrow to produce
normal blood cells.

How to use CYTOSAR 100MG INJECTION

CYTOSAR 100MG INJECTION will be given to you only by a doctor or a nurse beneath
the skin (subcutaneously) of thighs, arms or abdomen or into the vein
(intravenously). Your doctor will decide the correct dose and duration of
therapy for you depending upon your age, body weight and disease condition.

Side Effects Of CYTOSAR 100MG INJECTION

Serious

Consult your doctor immediately if you experience any of the following side
effects after receiving CYTOSAR 100MG INJECTION:

• sore mouth
• severe allergic reaction with symptoms of rashes, hives, swelling in arms, feet, ankles, face, lips, mouth, and throat with difficulty in breathing, swallowing, and speaking, feeling faint
• fever, chills, aches, soreness while swallowing (symptoms of infection)
• bleeding gums, blood in urine or vomit, unexpected bruising
• black tarry stools (signs of bleeding in the gut)
• severe chest pain with breathing difficulties (symptoms of pericarditis)
• severe pain in abdomen (signs of pancreatic inflammation)
• loss of vision, loss of touch tense, mental disturbances or loss of ability to move normally

Common

• low RBC count causing anemia
• tiredness and pale skin
• increased infections
• increased bleeding tendency due to low blood platelet counts
• loss of appetite
• high levels of uric acid in blood
• abnormal eye movements, eye pain, redness, inflammation, bleeding, sensitivity and burning sensation
• nausea, vomiting, diarrhea, mild stomach pain, ulcers in the anus (back passage)
• mouth ulcers, sore tongue
• liver problems
• skin rashes, itching, blistering and inflammation of blood vessels
• hair loss
• problems in passing urine
• injection site reactions (inflammation and blood clots)

Uncommon

• sepsis
• headache
• lung infection
• numbness or weakness in legs and arms
• paralysis of lower body
• sore throat, inflammation of food pipe
• inflammation in bowel and bowel cysts
• lentigo (brownish or blackish spots in skin)
• redness and blisters in hands and feet with pain
• muscle and joint pain

How To Manage Side Effects

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as
water or electrolytes. Applying a pain-relieving balm on your forehead can be
beneficial. Consult your doctor if your headache worsens.

!### Mouth Ulcers

Avoid eating spicy foods. Drink plenty of water. Apply a pain-relieving gel on
the affected areas of the mouth if required. Consult your doctor if the symptom
did not improve.

!### Nausea And Vomiting

Stick to simple meals. Avoid eating oil rich or spicy foods. If your nausea
worsens, consult your doctor for advice.

Warning & Precautions

!### Pregnancy

ContraindicatedCYTOSAR 100MG INJECTION is not recommended for use in pregnant women as it may
harm the growing baby. Women of childbearing potential must use a suitable
contrace
INJECTION and until 6 months after stopping the therapy.

!### Breastfeeding

ContraindicatedCYTOSAR 100MG INJECTION is not recommended for use in breastfeeding women.
Therefore, inform your doctor before receiving the medicine.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if your ability is affected by CYTOSAR
100MG INJECTION.

!### Kidney

Use with CautionCYTOSAR 100MG INJECTION should be used with caution in patients with kidney
diseases. Therefore, consult doctor before receiving it.

!### Liver

Use with CautionCYTOSAR 100MG INJECTION should be used with caution in patients with liver
diseases such as jaundice (yellowing of skin and whites of the eyes). Therefore,
consult doctor before receiving it.

!### Allergy

ContraindicatedDo not receive CYTOSAR 100MG INJECTION if you are allergic to Cytarabine.

!### Heart Disease

Use with CautionCYTOSAR 100MG INJECTION should be used with caution in patients with heart
diseases. Therefore, consult doctor before receiving it.

!### Use In Pediatrics

Monitoring requiredCYTOSAR 100MG INJECTION should be used in children and adolescents (aged below
18 years) only if prescribed by the physician. Therefore, consult your doctor
before receiving it.

!### Use In Geriatrics

Use with CautionCYTOSAR 100MG INJECTION should be used with caution in elderly patients (aged 65
years or above). Therefore, consult your doctor before receiving it.

Others

CYTOSAR 100MG INJECTION is not recommended for use if you:

• have low RBC, WBC and platelet counts in blood
• have developed any abnormal affects in brain (encephalopathy) after radiation

Before receiving CYTOSAR 100MG INJECTION inform your doctor if you have any of
the following conditions:

• low blood counts
• are currently undergoing or planning to undergo radiation therapy
• high blood uric acid levels
• undergoing any blood transfusions
• planning to receive any other vaccines

Interactions

A. Drug-Drug interactions:

Before receiving CYTOSAR 100MG INJECTION inform your doctor if you are taking
the following medicines such as:

• digoxin (a medicine used to manage irregular heart rate)
• gentamicin (a medicine used for infections)
• 5-fluorocytosine (a medicine used for fungal infection)
• medicines that reduce the activity of immune system (Ex. tacrolimus, prednisolone)

Overdosage:

CYTOSAR 100MG INJECTION will be administered only by a doctor or a nurse in a
hospital, and so it is unlikely to receive an overdose. However, consult your
doctor or nurse if you experience any unusual symptoms.

Synopsis

Drug	:	Cytarabine
Pharmacological Category	:	Cytidine Analogs
Therapeutic Indication	:	Blood cancer, Lymph cancer
Dosage Forms	:	Injection, Tablet

More Information

• Keep CYTOSAR 100MG INJECTION out of sight and reach of children
• Store CYTOSAR 100MG INJECTION at room temperature

FAQs About CYTOSAR 100MG INJECTION

Q: What CYTOSAR 100MG INJECTION is used for?

A: CYTOSAR 100MG INJECTION is used for certain types of blood cancer and lymph
cancer (Ex. acute myeloid leukemia, acute non-lymphoblastic/lymphoblastic
leukemia, chronic myeloid leukemia, non-Hodgkin’s lymphoma).

Q: What side effects are seen with CYTOSAR 100MG INJECTION?

A: The most common side effects of receiving CYTOSAR 100MG INJECTION are low
RBC, WBC and platelet counts causing anemia, increased infections and bleeding
tendency, loss of appetite, abnormal eye movements, eye pain, redness and
inflammation, nausea, vomiting, mouth ulcers, sore tongue, skin rashes, hair
loss and inflammation at the injection site. Consult your doctor if any of these
above side effect worsens.

Q: Who should avoid receiving CYTOSAR 100MG INJECTION?

A: CYTOSAR 100MG INJECTION is not recommended for use in pregnant and/or
breastfeeding women. It is also not recommended for use in patients suffering
from leukopenia (low white blood cell count), thrombocytopenia (low blood
platelet count), severe liver disease, or severe kidney diseases. Therefore,
consult your doctor before receiving it.

Q: Is CYTOSAR 100MG INJECTION safe for use in children?

A: CYTOSAR 100MG INJECTION should be used in children and adolescents (aged
below 18 years) only if prescribed by the physician. Therefore, consult your
doctor before receiving it.

Q: Can I consume alcohol while undergoing therapy with CYTOSAR 100MG
INJECTION?

A: Avoid consum
INJECTION as it could lead to unwanted side effects.

Q: Is it safe to drive or use machinery after received CYTOSAR 100MG
INJECTION?

A: Do not drive or operate any heavy tools or machines if you experience
dizziness, nausea, or vomiting after receiving CYTOSAR 100MG INJECTION.

Q: How CYTOSAR 100MG INJECTION works?

A: CYTOSAR 100MG INJECTION works by damaging the cellular genetic material
(DNA). This interferes with the functions of DNA and works against cancer cells
from multiplying. Therefore, it works against abnormal cell division within the
body.

Q: Can CYTOSAR 100MG INJECTION increase the risk of infections?

A: CYTOSAR 100MG INJECTION may cause a drop in the number of white blood cells
in the body and may weaken your immune system. As a result, you may be at a
greater risk of getting infected while receiving CYTOSAR 100MG INJECTION. To
avoid this, your doctor will regularly monitor your blood count. However, inform
your doctor if you experience any signs of infection such as fever.

Q: Can the use of CYTOSAR 100MG INJECTION cause hair loss?

A: Hair loss is one of the common side effects of receiving CYTOSAR 100MG
INJECTION. This side effect is usually temporary and disappears once after
therapy with this medicine stops completely. If it bothers you, consult your
doctor for advice.

Q: Can the use of CYTOSAR 100MG INJECTION make me feel tired?

A: Yes. CYTOSAR 100MG INJECTION may make you feel tired easily. This is because,
it reduces the levels of red blood cells in your blood and may make you anaemic.
Consult your doctor if you experience tiredness after receiving CYTOSAR 100MG
INJECTION. Tiredness can also occur if you have any pre-existing disease
conditions such as liver or kidney impairment while receiving this medicine.

Useful Diagnostic Tests

• Bone marrow smear microscopy examination
• Complete Blood Count
• Peripheral Smear Examination