Colif Tablet 10'S

Introduction About COLIF TABLET

COLIF TABLET is a combination of Dicyclomine, and Paracetamol which belongs to
the group of medicines called Antispasmodics, Analgesic and Anti-pyretic
respectively. It is used for the management of stomach cramps, renal and biliary
colic, as well as pain from gynaecologic or surgical conditions. It is also used
to manage functional bowel disease and irritable bowel syndrome (IBS).

Avoid consuming alcohol while taking COLIF TABLET, as it may increase the side
effects. COLIF TABLET is not recommended in patients with an unstable
cardiovascular condition with acute haemorrhage, myasthenia gravis, glaucoma,
obstructive uropathy, obstructive disease of the gastrointestinal tract, severe
ulcerative colitis, or reflux esophagitis.

COLIF TABLET should be used with caution in patients with severe liver and
kidney disease, hypertension, coronary heart disease, congestive heart failure,
cardiac tachyarrhythmia, psychosis, and delirium (such as elderly patients
and/or in patients with mental illness), incomplete intestinal obstruction (the
small intestine partially or totally blocked), patients with salmonella
dysentery, ulcerative colitis (inflammatory bowel disease), prostatic
hypertrophy (prostate gland enlargement), hyperthyroidism, alcoholism, and in
patients who take painkillers often for headache, etc.

COLIF TABLET should be used with caution in pregnant women, unless considered
necessary. COLIF TABLET is not recommended for use by breastfeeding women. COLIF
TABLET is not recommended for use by children under 10 years of age. COLIF
TABLET should be used with caution by elderly patients.

The most common side effects of taking COLIF TABLET are hypersensitivity
reactions, dry mouth, upset stomach, vomiting, constipation, and gas or
bloating. Contact your doctor if any of the symptoms get worse.

Uses Of COLIF TABLET

• Manage stomach cramps, renal and biliary colic, as well as pain from gynaecologic or surgical conditions
• Manage functional bowel disease and irritable bowel syndrome (IBS)

How COLIF TABLET Works

COLIF TABLET is an antispasmodic works by relaxing the muscles in your stomach
and gut (intestine). It manages unexpected muscular contractions (spasms). It
also reduces bloating, pain, cramps, and discomfort. Paracetamol is analgesics
and antipyretic as well works by inhibiting both COX-1 and COX-2 enzyme and
manages prostaglandin synthesis, thus reliefs pain.

How to use COLIF TABLET

Take COLIF TABLET as advised by your physician. With a glass of water, take the
tablet. Do not crush or chew the medicine. Depending on your age, body weight,
disease condition, your doctor will fix the correct dose and duration for you.

Side Effects Of COLIF TABLET

Common

• dizziness, drowsiness
• dry mouth
• vision blurred
• nausea
• weakness and nervousness

Stop taking COLIF TABLET and contact your physician immediately if you
experience any of the following side effects:

• serious allergic reaction such as rashes, hives, itching, red, swollen, blistered, shortness of breath, wheezing, cough, difficulty breathing, swallowing, or talking, swelling of the face, lips, tongue, or throat, legs and arms
• changes in blood cell types and numbers. If you notice an increase in the number of nosebleeds, or notice that you bruise easily, or get more infections
• fluttering or pounding in your chest, rapid or slow heartbeats
• hallucinations, anxiety, unusual thoughts, or actions
• difficulty with speech or memory
• difficulties in muscle movements or balance
• diarrhoea, severe constipation, or worsening bowel issues
• difficulty swallowing
• where a dicyclomine injection was administered, there is bruising, swelling, or pain
• dizziness, confusion, intense thirst, decreased urine or sweating are all symptoms of dehydration

How To Manage Side Effects

!### Constipation

Consume a lot of foods high in fibre, such as grains, fresh fruits, and
vegetables. Drink water and exercise regularly. Contact your doctor if
constipation persists.

!### Diarrhea

Drink plenty of water and fruit juice to keep yourself hydrated. Contact your
doctor if the diarrhoea did not improve.

!### Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operate machinery if
you feel drowsiness or dizziness. Avoid alcohol consum
dizziness or drowsiness. Contact your doctor if dizziness or drowsiness worsen.

!### Nausea And Vomiting

Take the medicine, with or just after a meal. Stick to simple meals. Avoid
eating oily or spicy food. If the nausea does not improve, consult your doctor.

Warning & Precautions

!### Pregnancy

Monitoring requiredCOLIF TABLET should be used with caution in pregnant women, unless considered
necessary. Contact your doctor before taking COLIF TABLET.

!### Breastfeeding

ContraindicatedCOLIF TABLET is not recommended in breastfeeding women. Contact your doctor
before taking COLIF TABLET.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines, while taking COLIF TABLET, or things that
require mental alertness, as it may cause blurred vision or drowsiness.

!### Alcohol

Consult your doctorAvoid consum
side effects.

!### Kidney

Use with CautionCOLIF TABLET should be used with caution in patients with severe kidney disease.
Contact your doctor before taking COLIF TABLET.

!### Liver

Use with CautionCOLIF TABLET should be used with caution in patients with severe liver disease.
Contact your doctor before taking COLIF TABLET.

!### Allergy

ContraindicatedDo not take COLIF TABLET if you are allergic to dicyclomine, or paracetamol or
to other ingredients of this medicine.

!### Heart Disease

Consult your doctorCOLIF TABLET is not recommended in patients with unstable cardiovascular
condition with acute haemorrhage and should be used with caution in patients
with hypertension, coronary heart disease, congestive heart failure, and cardiac
tachyarrhythmia. Contact your doctor before taking COLIF TABLET.

!### Use In Pediatrics

ContraindicatedCOLIF TABLET is not recommended for use in children under 10 years of age.
Contact your doctor before taking COLIF TABLET.

!### Use In Geriatrics

Use with CautionCOLIF TABLET should be used with caution in elderly patients. Contact your
doctor before taking COLIF TABLET.

Others

COLIF TABLET is not recommended for use if you have:

• myasthenia gravis
• glaucoma
• obstructive uropathy
• obstructive disease of the gastrointestinal tract
• severe ulcerative colitis
• reflux esophagitis

Before taking COLIF TABLET, inform your doctor if you have:

• heat prostration (such as fever and heat stroke because of decreased sweating)
• psychosis and delirium (such as elderly patients and/or in patients with mental illness)
• incomplete intestinal obstruction (small intestine partially or totally blocked)
• patients with salmonella dysentery
• ulcerative colitis (inflammatory bowel disease)
• prostatic hypertrophy (prostate gland enlargement)
• hyperthyroidism
• suffered from alcoholism
• take painkillers often for headache

Interactions

A. Drug-Drug interactions:

Tell your doctor if you have recently taken any other medicines, including
medicines obtained without a prescri
products:

• antiglaucoma agents
• other drugs with anticholinergic activity such as amantadine, antiarrhythmic agents of class I (Ex. quinidine), antihistamines, antipsychotic agents (Ex. phenothiazines), benzodiazepines, MAO inhibitors, narcotic analgesics (Ex. meperidine), nitrates and nitrites, tricyclic antidepressants, sympathomimetic drugs, and other medications with anticholinergic effects
• digoxin (medicine used for heart failure)
• warfarin (prevents blood clot)
• metoclopramide or domperidone (medicine used to manage nausea and vomiting)
• cholestyramine (medicine used to manage high cholesterol levels)
• imatinib (medicine used to manage leukaemia and some stomach tumours)

Overdosage:

If you or anyone else accidentally take too much of COLIF TABLET, consult your
doctor immediately or visit the nearby hospital. Signs and symptoms of overdose
may include headache, nausea, vomiting, blurred vision, dilated pupils, hot, dry
skin, dizziness, dryness of the mouth, difficulty in swallowing, CNS stimulation
including convulsion, loss of appetite, stomach pain and liver damage.

Synopsis

Drug	:	Dicyclomine, Paracetamol
Pharmacological Category	:	Antispasmodics, Analgesic and Antipyretics
Therapeutic Indication	:	Relief pain & and irritable bowel syndrome (IBS)
Dosage Forms	:	Tablet

More Information

• Keep COLIF TABLET out of reach of children
• Store COLIF TABLET below 25°C

FAQs About COLIF TABLET

Q: What is COLIF TABLET used for?

A: COLIF TABLET is used for the management of stomach cramps, renal and biliary
colic, as well as pain from gynecologic or surgical conditions. It is also used
to manage functional bowel disease and irritable bowel syndrome (IBS). Consult
your doctor before taking COLIF TABLET.

Q: What are the side effects of taking COLIF TABLET?

A: The most common side effects of taking COLIF TABLET are hypersensitivity
reactions, dry mouth, upset stomach, vomiting, constipation, and gas or
bloating. Contact your doctor if any of the symptoms get worse.

Q: Is COLIF TABLET safe during pregnancy?

A: COLIF TABLET should be used with caution in pregnant women, unless considered
necessary. Contact your doctor before taking COLIF TABLET.

Q: Is COLIF TABLET safe during breast-feeding?

A: COLIF TABLET is not recommended for breastfeeding women. Contact your doctor
before taking COLIF TABLET.

Q: Can we use COLIF TABLET in children?

A: COLIF TABLET is not recommended for use by children under 10 years of age.
Contact your doctor before taking COLIF TABLET.

Q: How does COLIF TABLET work?

A: COLIF TABLET is an antispasmodic that works by relaxing the muscles in your
stomach and gut (intestine). It manages unexpected muscular contractions
(spasms). It also reduces bloating, pain, cramps, and discomfort. Paracetamol is
an analgesic and an antipyretic as well. It works by inhibiting both COX-1 and
COX-2 enzymes and managing prostaglandin synthesis, thus relieving pain.

Q: Is COLIF TABLET good for stomach pain?

A: COLIF TABLET relieves stomach and intestinal cramps, muscle spasms, abdominal
pain, constipation, and other GI discomforts by relaxing the muscles and
managing normal gut movements.

Q: Is COLIF TABLET used for periods?

A: COLIF TABLET helps to relieve the symptoms of menstrual (period-related) pain
and cramping.