Cliface Lotion 25ml

Introduction About CLIFACE LOTION

CLIFACE LOTION contains Clindamycin, which belongs to the group of medicines
called Antibiotics. It is used in the management of acne vulgaris. Acne vulgaris
is a common skin condition that occurs when hair follicles get blocked with oil
and dead skin cells. Symptoms include whiteheads, blackheads, small red, tender
bumps, pimples, and pus-filled lumps on the skin.

Before applying CLIFACE LOTION, inform your doctor if you have or ever had
diarrhea, bloody diarrhea and pseudomembranous colitis. CLIFACE LOTION is not
recommended for use if you have a history of regional enteritis (inflammation of
the small intestine), ulcerative colitis (inflammation of the large intestine)
or antibiotic-associated colitis.

CLIFACE LOTION should be used with caution during pregnancy or by breastfeeding
women only if clearly needed. The safety and effectiveness of CLIFACE LOTION in
children under the age of 12 has not been established. The most common side
effects of applying CLIFACE LOTION are burning, itching, and redness of the
skin. Consult your doctor if symptoms worsen.

Uses Of CLIFACE LOTION

• Manage acne vulgaris

How CLIFACE LOTION Works

CLIFACE LOTION acts against the bacteria by binding to the 50S subunit of the
bacterial ribosome (site of protein synthesis), which in turn manages protein
synthesis and kills the infection-causing bacteria.

How to use CLIFACE LOTION

Apply CLIFACE LOTION as advised by your physician. It is for external use only.
Wash your hands before use. Wash and dry the whole area, apply a thin film once
daily to the skin where acne lesions appear and use enough to cover the entire
affected area. In case of contact with the eyes, mouth or nostrils, rinse it off
immediately and thoroughly with water. Your doctor will decide the correct dose
and duration for you depending on your age, body weight and disease condition.

Side Effects Of CLIFACE LOTION

Common

• burning, itching or abnormal redness of the skin at the application site
• scaling, pain, dryness and skin irritation at the application site

Uncommon

• abdominal pain
• diarrhea
• oily skin

Rare

• antibiotic-associated colitis

Stop applying CLIFACE LOTION and contact your doctor immediately if you
experience any of the following side effects:

• allergic symptoms (e.g., rashes, itchiness, difficulty in breathing or eye swelling)
• severe or bloody diarrhea. (a sign of bowel inflammation, pseudomembranous colitis)

Warning & Precautions

!### Pregnancy

The safety and effectiveness of CLIFACE LOTION in pregnant women or women
planning to have a baby have not been established yet. It will be given to you
by the doctor only if clearly needed. Consult your doctor before applying
CLIFACE LOTION.

!### Breastfeeding

CLIFACE LOTION should be used with caution in breastfeeding women as it is not
known if the medicine is excreted in human milk. Your doctor will decide whether
to discontinue nursing or the medicine, considering the benefits to the mother
and baby. If it is applied to the chest, care should be taken to avoid
accidental ingestion by the infant. Consult your doctor before applying CLIFACE
LOTION.

!### Allergy

Do not apply CLIFACE LOTION if you are allergic to Clindamycin or any other
ingredients of this medicine.

Others

CLIFACE LOTION is not recommended for use if you:

• have regional enteritis (inflammation of the small intestine) or ulcerative colitis (inflammation of the large intestine)
• have a history of antibiotic-associated colitis

Before applying CLIFACE LOTION inform your doctor if you:

• diarrhea, bloody diarrhea
• pseudomembranous colitis (inflammation of colon)
• atopic individuals (more prone to allergies)

Use in pediatrics:

Safety and effectiveness of CLIFACE LOTION in children under the age of 12 have
not been established. Consult your doctor before applying CLIFACE LOTION.

Interactions

A. Drug-Drug interactions:

Before applying CLIFACE LOTION, inform your doctor if you are taking any of the
following medicine:

• neuromuscular blocking agents (Ex. rocuronium, vecuronium)
• other anti-acne, topical agents

Overdosage:

If you or anyone else accidentally applied too much of CLIFACE LOTION, consult
your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Clindamycin
Pharmacological Category	:	Lincosamides
Therapeutic Indication	:	Acne vulgaris
Dosage Forms	:	Injection, Tablet, Capsule, Gel, Cream, Lotion, Solution, Spray, Soap

More Information

• Keep CLIFACE LOTION out of reach from children
• Store at room temperature

FAQs About CLIFACE LOTION

What is CLIFACE LOTION used for?

CLIFACE LOTIONis used in the management of acne vulgaris. Acne vulgaris is a
common skin condition that occurs when hair follicles get blocked with oil and
dead skin cells. Symptoms include whiteheads, blackheads, small red, tender
bumps, pimples, and pus-filled lumps on the skin.

How to use CLIFACE LOTION?

Apply CLIFACE LOTION as advised by your physician. It is for external use only.
Wash your hands before use. Wash and dry the whole area, apply a thin film once
daily to the skin where acne lesions appear and use enough to cover the entire
affected area. In case of contact with the eyes, mouth or nostrils, rinse it off
immediately with plenty of water.

How does CLIFACE LOTION work?

CLIFACE LOTION acts against the bacteria by binding to the 50S subunit of the
bacterial ribosome (site of protein synthesis), which in turn manages protein
synthesis and kills the infection-causing bacteria.

Can CLIFACE LOTION be used in pregnancy?

The safety and effectiveness of CLIFACE LOTION in pregnant women or women
planning to have a baby have not been established yet. It will be given to you
by the doctor only if clearly needed. Consult your doctor before applying
CLIFACE LOTION.

Can CLIFACE LOTION be used in breastfeeding women?

CLIFACE LOTION should be used with caution in breastfeeding women as it is not
known if the medicine is excreted in human milk. Your doctor will decide whether
to discontinue nursing or the medicine, considering the benefits to the mother
and baby. If it is applied to the chest, care should be taken to avoid
accidental ingestion by the infant. Consult your doctor before applying CLIFACE
LOTION.