Ciplox 750mg Tablet 10'S

Introduction About CIPLOX 750MG TABLET

CIPLOX 750MG TABLET contains ciprofloxacin, which belongs to the group of
medicines called fluoroquinolone antibiotics. It is used in adults in the
management of bacterial infections of the respiratory tract, ear and sinus,
urinary tract, genital tract, gastrointestinal tract, skin and soft tissue, bone
and joint as well as anthrax inhalation exposure infections. The medicine is
also used in the management of fever in neutropenia-associated infections.

CIPLOX 750MG TABLET on prolonged use can cause an overgrowth of other
non-susce
taken for the first time. Caution should be taken in elderly patients while
taking CIPLOX 750MG TABLET as it can result in prolonged QT intervals.

Before taking CIPLOX 750MG TABLET, inform your doctor if you are having kidney
problems, neurological conditions, or heart diseases such as a tear in the
aortic wall of the heart, bulge, or large blood vessels, leaking in the heart
valves and congenital heart disease or myasthenia gravis.

CIPLOX 750MG TABLET is generally not recommended during pregnancy and
breastfeeding. The most common side effect of taking CIPLOX 750MG TABLET is
nausea and diarrhoea. Consult a doctor immediately if any of the symptoms
worsen.

Uses Of CIPLOX 750MG TABLET

CIPLOX 750MG TABLET is used in adults to manage bacterial infections of the
following:

• respiratory tract infections
• recurring ear and sinusitis infections
• urinary tract infections
• genital tract infections
• gastrointestinal tract infections
• intraabdominal infections
• skin and soft tissue infections
• bone and joint infections
• anthrax inhalation exposure

How CIPLOX 750MG TABLET Works

CIPLOX 750MG TABLET contains Ciprofloxacin which is an antibacterial agent that
acts by managing bacterial replication by targeting the essential enzyme inside
the bacteria. This leads to the restriction of growth of the disease-causing
bacteria inside the infected person and thereby helps to control the infection
and manage its symptoms caused by it.

How to use CIPLOX 750MG TABLET

Take CIPLOX 750MG TABLET as advised by your physician. Try to take the medicine
after meals. Swallow CIPLOX 750MG TABLET with a glass of water. Do not crush or
chew the medicine. Your doctor will decide the correct dose and duration for you
depending upon your age, body weight and disease condition.

Side Effects Of CIPLOX 750MG TABLET

Common

• nausea
• diarrhoea

Uncommon

• fungal superinfections (serious fungal infections)
• loss of appetite
• taste disorders
• vomiting
• stomach pain
• wind (flatulence)
• indigestion and heartburn
• hyperactivity, agitation
• headache, dizziness, sleeping problems
• allergic reaction such as itching, hives, rash
• poor kidney function
• joint pain in adults
• pains in muscles and bones
• feeling unwell (asthenia)
• fever
• fluid retention
• high concentration of eosinophils (type of white blood cell)
• increased amounts of certain substances in the blood (transaminases, bilirubin or alkaline phosphatase levels)

Rare

• muscle pain, inflammation of the joints, increased muscle tone and cramping
• inflammation of the bowel (colitis) linked to antibiotic use
• changes to the blood count (leukopenia, leucocytosis, neutropenia, anaemia pancytopenia), bone-marrow depression
• allergic reaction such as swelling (oedema) rapid swelling of the skin and mucous membranes (angioedema)
• increased blood sugar (hyperglycaemia), decreased blood sugar (hypoglycaemia)
• anxiety reaction, strange dreams, depression
• decreased skin sensitivity, tremors, migraine, altered sense of smell (olfactory disorders)
• tinnitus (ringing noise in the ear), impaired hearing
• fainting, inflammation of the blood vessel (vasculitis)
• shortness of breath including asthmatic symptoms
• pancreatitis, hepatitis (inflammation of liver and pancreas), death of liver cells (liver necrosis)
• sensitivity to light, pin-point bleeding under the skin (petechiae)
• blood or crystals in the urine, urinary tract inflammation
• excessive sweating
• increased levels of the enzyme amylase
• pain and swelling in the joints, and inflammation or rupture of tendons
• nerve damage (neuropathy) such as pain, burning, tingling, numbness, and weakness especially in the feet and legs or hands and arms

Stop taking CIPLOX 750MG TABLET and consult your doctor immediately if you
experience any of the following side effects:

• sensory disorders including impairment of vision, taste and smell, and hearing, depression, memory impairment, severe fatigue, and severe sleep disorders.
• severe allergic reaction with symptoms such as tightness in the chest, feeling dizziness, feeling sick, fainting, and experience dizziness while standing
• impairment of eyesight, taste, smell, hearing
• pain and swelling of tendons (Ex. in your ankle, wrist, elbow, shoulder or knee), difficulty in walking
• cerebral ischemia (less blood flow to the brain) or stroke, seizure (fits)
• mental disturbances (psychiatric reactions such as depression and potentially leading to suicidal thoughts, suicidal attempts, or completed suicide), memory impairment and sleep disturbances
• nerve damage (neuropathy) in the feet and legs or hands and arms causing symptoms such as pain, burning, tingling, numbness or weakness
• increase in blood sugar levels (hyperglycaemia), or lowered blood sugar levels below normal levels, in severe cases can lead to loss of consciousness or coma
• sudden shortness of breath, especially while lying down flat, rapid irregular heartbeat and swelling of your ankles, feet or abdomen
• presence of crystals in the urine with discomfort when passing urine (crystalluria)
• false Tuberculosis test (Mycobacterium)
• sensitive skin to sunlight or ultraviolet (UV) light
• liver damage leading to symptoms such as loss of appetite, yellowing of the skin, urine dark in colour, itching or pain in the stomach,
• infection with symptoms such as fever and serious deterioration of your general condition, or fever with local infection symptoms such as sore throat/pharynx/mouth or urinary problems

How To Manage Side Effects

Nausea and vomiting:

Take this medicine with or just after a meal or a snack. Stick to simple meals.
Avoid eating rich or spicy food.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated.
Avoid taking any medicine on your own for managing diarrhoea. Consult your
doctor if the symptom did not improve.

Skin rash:

Avoid hot showers because hot water can irritate your skin further. Do not
scratch the affected area. Use protective clothing when going outdoors.
Regularly moisturize your skin. Consult your doctor if the symptom did not
improve.

Warning & Precautions

!### Pregnancy

CIPLOX 750MG TABLET is not recommended for pregnant and planning to get pregnant
women. Consult your doctor before taking CIPLOX 750MG TABLET.

!### Breastfeeding

CIPLOX 750MG TABLET is generally not recommended for use in breastfeeding women
as it may pass through breast milk and could be harmful to the baby. Consult
your doctor before taking CIPLOX 750MG TABLET.

!### Driving and Using Machines

Do not drive or use heavy machinery after taking CIPLOX 750MG TABLET as the
medicine could cause dizziness and can potentially reduce your attention.
Consult your doctor before taking CIPLOX 750MG TABLET.

!### Alcohol

Avoid consum
make you feel dizzier. Consult your doctor before taking CIPLOX 750MG TABLET.

!### Kidney

CIPLOX 750MG TABLET should be taken with caution in patients with severe kidney
problems. Consult your doctor before taking CIPLOX 750MG TABLET.

!### Liver

CIPLOX 750MG TABLET should be taken with caution in patients with severe liver
damage. Consult your doctor before taking CIPLOX 750MG TABLET.

!### Allergy

Do not take CIPLOX 750MG TABLET if you are allergic to ciprofloxacin or any
other quinolone antibiotics.

!### Heart Disease

CIPLOX 750MG TABLET should be used with caution in patients suffering from heart
problems such as prolonged QT interval (seen on ECG, electrical recording of the
heart), have very slow heart rhythm (bradycardia), weak heart (heart failure),
history of heart attack, leaking of heart valves, tearing in the aortic wall,
bulging of a large blood vessel, if you have taken any medicine that cause
abnormal ECG changes, and congenital heart valve disease. Consult your doctor
before taking CIPLOX 750MG TABLET.

Others

Before taking CIPLOX 750MG TABLET, inform your doctor if you

• suffer from epilepsy or other neurological conditions

• have tendon problems during previous management with antibiotics

• have a history of diabetes

• have a disease that causes muscle weakness (myasthenia gravis)

• have a deficiency in glucose-6-phosphate dehydrogenase (G6PD

• have a history of connective tissue disorder such as

• Marfan syndrome or Ehlers-Danlos syndrome

• Turner syndrome (chromosomal defect)

• Sjogren’s syndrome (an inflammatory autoimmune disease)

• vascular disorders such as Takayasu arteritis giant cell arteritis

• Behcet’s disease (blood vessel inflammation throughout your body)

• rheumatoid arthritis (a disease of the joints)

• endocarditis (an infection of the heart)

Use in geriatrics:

CIPLOX 750MG TABLET should be used with caution in elderly patients (above 60
years of age) especially in those with impaired kidney function. Consult your
doctor before taking CIPLOX 750MG TABLET.

Interactions

A. Drug-Drug interactions:

Before taking CIPLOX 750MG TABLET, inform your doctor if you are taking any of
the following medicine:

• vitamin K antagonists (Ex. warfarin, acenocoumarin, phenprocoumon or fluindione)
• other oral anti-coagulants Ex. dabigatran, rivaroxaban, apixaban, edoxaban and betrixaban (medicine to thin the blood)
• probenecid (medicine used to manage gout)
• methotrexate (medicines used for certain types of cancer, psoriasis, rheumatoid arthritis)
• theophylline (medicine used to manage breathing problems)
• tiz
• olanzapine, clozapine, risperidone (medicine used for anti-psychosis)
• ropinirole (medicine used to manage Parkinson’s disease)
• phenytoin (medicine used to manage epilepsy)
• cyclosporin (medicine used to manage skin conditions, rheumatoid arthritis, and organ transplantation)
• other medicines that are used to manage alteration in heart rhythm (medicines that belong to the group of antiarrhythmics such as quinidine, hydroquinone, disopyramide, amiodarone, sotalol, dofetilide, ibutilide)
• tricyclic antidepressants (medicine that are used to manage depression such as doxepin and amoxapine)
• some antimicrobials (that belong to the group of macrolides such as azithromycin, clarithromycin)
• zolpidem (medicine to manage sleep disorders)
• pentoxifylline (medicine to manage circulatory disorders)
• caffeine (medicine used to stimulate the central nervous system)
• duloxetine (medicine used to manage depression, diabetic nerve damage or incontinence)
• lidocaine (medicines used to manage heart conditions or anaesthetic use)
• sildenafil (medicine used to manage erectile dysfunction)
• agomelatine (medicine used to manage major depressive disorder)
• meprazole, sucralfate (medicine used to manage indigestion and heartburn)
• iron, zinc (medicine used as mineral supplements)
• a polymeric phosphate binder (Ex. sevelamer or lanthanum carbonate)
• medicines or supplements containing calcium, magnesium, aluminium or iron

B. Drug-Food interaction:

Avoid eating or drinking any dairy products (such as milk or yoghurt) or drinks
with added calcium while taking CIPLOX 750MG TABLET, as they may affect the
absor

If you or anyone else accidentally took more of CIPLOX 750MG TABLET, consult
your doctor immediately or visit the nearby hospital.

Synopsis

Drug	:	Ciprofloxacin
Pharmacological Category	:	Fluoroquinolone antibiotics
Therapeutic Indication	:	Manage specific kinds of bacterial infections
Dosage Forms	:	Tablets, Injections, Infusions, Drops, Dry Syrup, Eye ointment, Eye drops, Ointment, Ear drops

More Information

• Keep out of reach from children
• Store at room temperature

FAQs About CIPLOX 750MG TABLET

What is CIPLOX 750MG TABLET used for?

CIPLOX 750MG TABLET is used in adults in the management of bacterial infections
of the respiratory tract, ear and sinus, urinary tract, genital tract,
gastrointestinal tract, skin and soft tissue, bone and joint, as well as anthrax
inhalation exposure infections. CIPLOX 750MG TABLET is also used in the
management of fever in patients with neutropenia-associated infection. Use of
CIPLOX 750MG TABLET in children and adolescents is to manage lung and bronchial
infections with cystic fibrosis and complicated urinary tract infections,
including infections that cause pyelonephritis (a kidney infection that needs
immediate medical attention). Consult your doctor before taking CIPLOX 750MG
TABLET.IsCIPLOX 750MG TABLETsafe to take?

CIPLOX 750MG TABLET is a relatively safe drug. However, the complications are
more comparable to other drugs and hence should only be strictly taken if
prescribed by a doctor for your present condition in the appropriate dose,
frequency, and duration as advised.

Can I skip the dose ofCIPLOX 750MG TABLET?

No. You should complete the full course of CIPLOX 750MG TABLET as prescribed by
your doctor. It is important that CIPLOX 750MG TABLET be taken at the right dose
and for the right duration given. Otherwise, the symptoms can prevail and
sometimes worsen.

Can the use of CIPLOX 750MG TABLET cause diarrhoea?

Yes, the use of CIPLOX 750MG TABLET can cause diarrhoea. It is an antibiotic
that eliminates harmful bacteria. However, it also attacks the helpful bacteria
in your stomach or intestine and causes diarrhoea. Consult your doctor if you
are experiencing severe diarrhoea after taking CIPLOX 750MG TABLET.

Can CIPLOX 750MG TABLET increase the risk of muscle damage?

Yes, the use of CIPLOX 750MG TABLET is known to increase the risk of muscle
damage, commonly in the ankle (Achilles tendon). Muscle damage can happen in
people of all ages who take CIPLOX 750MG TABLET. Inform your doctor if you feel
any kind of muscle pain while using this medicine.

What will happen if I accidentally take more ofCIPLOX 750MG TABLET?

If you have accidentally overdosed on CIPLOX 750MG TABLET, you may suffer from
reversible kidney toxicity. In such cases, adequate hydration should be
maintained. Hence, drink plenty of fluids, to avoid further complications. And
consult a doctor immediately and visit the nearby hospital.

Can CIPLOX 750MG TABLET be given to breastfeeding mothers?

CIPLOX 750MG TABLET tablet is not recommended for breastfeeding mothers, as the
medicine could harm the child. Consult your doctor if you are breastfeeding
before you start taking this medication for infections.

Can I take CIPLOX 750MG TABLET for my cough and flu?

No, CIPLOX 750MG TABLET is an antibacterial medicine that acts only against
specific kinds of bacterial infections and not against viral infections causing
cough and flu. You should not self-medicate CIPLOX 750MG TABLET without prior
consultation with a doctor. Self-prescri
efficacy and therapeutic outcome of CIPLOX 750MG TABLET leading to antibiotic
resistance.

Useful Diagnostic Tests

• Complete Blood Count
• Peripheral Smear Examination