Celtranz 500Mg Injection 5ml

Introduction About CELTRANZ 500MG INJECTION

CELTRANZ 500MG INJECTION contains Tranexamic Acid which belongs to the group of
medicines called Antifibrinolytics. It is used in the management of bleeding in
conditions such as heavy menstrual bleeding in women, gastrointestinal bleeding
(bleeding in digestive tract, anywhere from the throat to rectum), bleeding due
to thrombolytic therapy (medicine that is used to breakdown blood clots) and
after having surgeries (such as ear, nose, throat, prostate gland, urinary
tract, gynecological, abdominal or heart surgery) in adults and children above
one year of age.

CELTRANZ 500MG INJECTION is not recommended for use in patients with severe
kidney impairment, blood clotting disorder or consum
(condition affecting the blood’s ability to clot and stop the bleeding) or
history of seizures (fits). Your doctor may recommend you to take relevant tests
to understand your existing condition.

Before receiving CELTRANZ 500MG INJECTION, inform your doctor if you had or have
blood in the urine, are at risk of having a blood clot, excessive clotting or
bleeding throughout the body (disseminated intravascular coagulation).

CELTRANZ 500MG INJECTION is not recommended for use in the first trimester of
pregnancy and in breast-feeding women. It should be used with caution in
pregnant women only if clearly advised by the doctor. CELTRANZ 500MG INJECTION
should be used with caution in elderly patients, especially in patients with the
evidence of renal failure.

The most common side effects of receiving CELTRANZ 500MG INJECTION are nausea or
vomiting and diarrhea. Inform your doctor immediately if any of the side effect
worsens.

Uses Of CELTRANZ 500MG INJECTION

Prevent and manages bleeding in children (aged above one) and adults in
conditions such as:

• heavy menstrual bleeding in women
• gastrointestinal bleeding
• after having surgeries (such as ear, nose, throat, heart, abdominal, gynaecological and prostrate or urinary tract surgery)
• bleeding due to medicine that is used to breakdown blood clots (thrombolytic therapy)

How CELTRANZ 500MG INJECTION Works

CELTRANZ 500MG INJECTION manages bleeding by blocking the plasminogen from
binding with fibrin which results in bleeding. As a result, it manages and
controls bleeding associated with various factors.

How to use CELTRANZ 500MG INJECTION

CELTRANZ 500MG INJECTION will be given to you only by a doctor or a nurse into a
vein as an intravenous injection. Your doctor will decide the correct dose,
frequency and duration for you depending upon your age, body weight and disease
condition.

Side Effects Of CELTRANZ 500MG INJECTION

Common

• diarrhea
• nausea, vomiting

Uncommon

• skin rashes

Rare

Inform your doctor immediately if you experience any of the following side
effects while receiving CELTRANZ 500MG INJECTION:

• severe allergic reaction (signs include redness of the skin and lumpy skin rashes, difficulty in breathing, swelling of face, mouth, lips or eyelids, unexplained high temperature (fever) and fainting)
• swelling of the throat that causes breathing and swallowing difficulty
• symptoms of a blood clot (such as swelling or pain in the legs or chest, headache, weakness of the face and limbs on one side of the body)

How To Manage Side Effects

!### Diarrhea

Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating
high-fat or spicy foods. Inform your doctor if the symptom gets worse.

!### Nausea And Vomiting

Stick to simple meals while receiving this medicine. Avoid eating oily rich,
fried or spicy foods. Do not lie down or sleep immediately after eating. Inform
your doctor if the symptom does not improve.

Warning & Precautions

!### Pregnancy

ContraindicatedCELTRANZ 500MG INJECTION is not recommended for use in the first trimester of
pregnancy. It should be used with caution in pregnant women only if considered
clearly necessary. Women of childbearing potential should use effective
contrace
receiving CELTRANZ 500MG INJECTION.

!### Breastfeeding

ContraindicatedCELTRANZ 500MG INJECTION is not recommended for use in breastfeeding women as it
passes through breast milk. Consult your doctor for advice.

!### Kidney

Consult your doctorCELTRANZ 500MG INJECTION is not recommended for use in patients with severe
kidney impairment. It should be used with caution in patients with mild to
moderate kidney impairment. Your doctor may adjust the dose depending upon the
kidney function. Consult your doctor before receiving CELTRANZ 500MG
INJECTION.

!### Liver

Use with CautionCELTRANZ 500MG INJECTION can be used with caution in patients with liver
impairment. Consult your doctor before receiving CELTRANZ 500MG INJECTION.

!### Allergy

ContraindicatedDo not receive CELTRANZ 500MG INJECTION if you are allergic to Tranexamic acid
or any other ingredients of this medicine.

!### Use In Pediatrics

Use with CautionCELTRANZ 500MG INJECTION should be used with caution in children above 1 year of
age. Your child’s doctor will adjust the dose based on the bodyweight of the
child. Consult child’s doctor for advice before administration of CELTRANZ 500MG
INJECTION.

!### Use In Geriatrics

Use with CautionCELTRANZ 500MG INJECTION should be used with caution in elderly patients,
especially in patients with the evidence of renal failure. Consult your doctor
before receiving CELTRANZ 500MG INJECTION.

Others

CELTRANZ 500MG INJECTION is not recommended for use if you:

• have blood clotting disorder or consum
• have history of seizures (fits)

Before receiving CELTRANZ 500MG INJECTION, inform your physician if you:

• have blood in the urine (which may lead to urinary tract obstruction)
• are at risk of having a blood clot
• have excessive clotting or bleeding throughout the body (disseminated intravascular coagulation)

Interactions

A. Drug-Drug interactions:

Before receiving CELTRANZ 500MG INJECTION, inform your doctor if you have
received or taking any of the following medicines:

• ethinyl estradiol, levonorgestrel (oral contrace
• thrombolytic agents such as streptokinase, reteplase, tenecteplase (medicines that manage blood clot)
• antifibrinolytics such as aminocaproic acid, aprotinin (medicines that help the blood to clot)

Overdosage:

CELTRANZ 500MG INJECTION will be given to you only by a doctor or nurse in a
hospital, and so it is unlikely to receive an overdose. However, if you
experience any unusual symptoms contact your doctor immediately. Symptoms
include dizziness, headache, low blood pressure and convulsions (fits).

Synopsis

Drug	:	Tranexamic Acid
Pharmacological Category	:	Antifibrinolytics
Therapeutic Indication	:	Prevent and manages bleeding in certain conditions
Dosage Forms	:	Injection, Gel, Tablet

More Information

• Store at room temperature

FAQs About CELTRANZ 500MG INJECTION

Q: CanCELTRANZ 500MG INJECTION be used in elderly patients?

A: CELTRANZ 500MG INJECTION should be used with caution in elderly patients,
especially in patients with the evidence of renal failure. Consult your doctor
for advice before receiving CELTRANZ 500MG INJECTION.

Q: Is CELTRANZ 500MG INJECTION safe to use during pregnancy?

A: CELTRANZ 500MG INJECTION is not recommended for use in the first trimester of
pregnancy. It should be used with caution in pregnant women only if clearly
advised by the doctor. Women of childbearing potential should use effective
contrace
receiving CELTRANZ 500MG INJECTION.

Q: CanCELTRANZ 500MG INJECTION be used in patients with impaired kidney
function?

A: CELTRANZ 500MG INJECTION is not recommended for use in patients with severe
kidney impairment. It should be used with caution in patients with mild to
moderate kidney impairment. Your doctor may adjust the dose depending upon the
kidney function. Consult your doctor before receiving CELTRANZ 500MG
INJECTION.

Q: Does CELTRANZ 500MG INJECTION cause nausea?

A: Yes, CELTRANZ 500MG INJECTION may cause nausea in some individuals. To manage
this effect, stick to simple meals while receiving this medicine. Avoid eating
oily rich, fried or spicy foods. Do not lie down or sleep immediately after
eating. Inform your doctor if the symptom does not improve.

Q: HowCELTRANZ 500MG INJECTION is administered?

A: CELTRANZ 500MG INJECTION will be given to you only by a doctor or a nurse
into a vein as an intravenous injection. It should not be injected into a muscle
(intramuscularly). Your doctor will decide the correct dose, frequency and
duration for you depending upon your age, body weight and disease condition.

Useful Diagnostic Tests

• Complete blood count
• Liver function test
• Kidney function test
• Bleeding Time/clotting time
• Eye test