Cardiopril H 2.5mg Tablet 10'S

Introduction About CARDIOPRIL H 2.5MG TABLET

CARDIOPRIL H 2.5MG TABLET is a combination of Ramipril and
Hydrochlorothiazidewhich belongs to the group of medicines called
Angiotensin-converting enzyme (ACE) inhibitors and Diuretics respectively. It is
used in the management of essential hypertension.

Hypertension is a condition in which force of the blood is consistently high
against the walls of the arteries which can increase the risk of heart disease,
kidney disease and stroke.

Before taking CARDIOPRIL H 2.5MG TABLET, inform your doctor if you are pregnant
or breast-feeding. Inform your doctor if you have any problems related to
kidney, liver, lungs or heart and if you have other conditions such as diabetes,
gout, myopia, glaucoma, collagen vascular disease or parathyroid disease.

CARDIOPRIL H 2.5MG TABLET is not recommended for use in children and adolescents
less than 18 years of age. If you are taking any other medicines for other
conditions or if you have history of allergy, inform to your doctor as it may
manage drug-related interactions and serious side effect.

The most common side effect of CARDIOPRIL H 2.5MG TABLET are headache,
dizziness, stomach pain, tiredness and nausea. Consult your doctor for advice if
your symptoms get worsen over the time.

Uses Of CARDIOPRIL H 2.5MG TABLET

• Used to manage essential hypertension (high blood pressure)

How CARDIOPRIL H 2.5MG TABLET Works

CARDIOPRIL H 2.5MG TABLET helps to reduce high blood pressure, where Ramipril
works by inhibiting the activity of an enzyme called Angiotensin converting
enzyme (an enzyme which is responsible for causing constriction of blood
vessels) which enhances easy flow of blood around the body. Hydrochlorothiazide
works by decreasing the extra fluid volume also works by managing reabsor
of sodium in the kidneys, which in turn it relaxes the blood vessels and
makes the blood flow more easily in the passage of blood vessels and thus lowers
the blood pressure.

How to use CARDIOPRIL H 2.5MG TABLET

Always take CARDIOPRIL H 2.5MG TABLET as directed by your physician. Take this
medicine with or without food, swallow the medicine as a whole and do not crush
or chew the medicine. Your doctor will prescribe the right dose depends on your
child’s age, body weight and disease condition.

Side Effects Of CARDIOPRIL H 2.5MG TABLET

Common

• headache
• tiredness
• dizziness
• orthostatic hypotension (dizziness while standing up from sitting or lying position)
• dry cough, inflammation of sinus
• stomach pain, indigestion
• diarrhea
• nausea
• chest pain
• pain or cramps in muscles
• signs of high potassium levels in the blood (muscle weakness, chest pain, irregular heartbeat)

Uncommon

• numbness, tingling, pricking, burning or creeping sensation in arms, legs or feet
• altered taste sensation, loss of appetite
• sleep problems
• depression, anxious, restlessness
• heartburn, dry mouth
• constipation
• increased urination
• excess sweating
• increased or irregular heartbeats
• flushing
• blurred vision
• fever
• reduced libido in men or women
• joint pain

Rare

• red and swollen tongue
• nail problems (loosening or separation of a nail from its bed)
• cold hands or feet
• anemia
• hearing problems or ringing in ear sensation
• signs of low while blood cells (fever, infections, mouth sores)
• signs of low platelet count (easy bruising or bleeding)

Stop taking CARDIOPRIL H 2.5MG TABLET and contact your doctor immediately if you
experience any of the following side effects:

• severe allergic reactions (such as swelling of the face, lips, tongue and/or throat which can lead to difficulty in breathing or swallowing, as well as itching and rashes)
• severe skin reactions such as stevens johnson syndrome, toxic epidermal necrolysis or erythema multiforme (such as rash, blistering, reddening and detachment of skin, mouth ulcers and worsening of previous skin disease)
• signs of lung problems (such as shortness of breath or cough)
• fast or irregular heartbeat, chest pain, chest tightness, including heart attack or stroke
• signs of inflamed pancreas (such as severe stomach and back pain)
• signs of liver problems such as hepatitis or liver damage (such as fever, chills, loss of appetite, stomach pain, nausea, (jaundice) yellowing of skin or white of the eyes)
• signs of blood or bone marrow problems (such as easy bruising, prolonged bleeding, bleeding from gums, purple spot and blotches on the skin, sore throat, repeated infections, pale skin, tiredness, fainting and dizziness)

How To Manage Side Effects

Diarrhoea:

Drink plenty of fluids such as water, fruit juices or electrolytes (ORS) to
avoid dehydration in your body. Consult your doctor if your symptom does not
improve.

Nausea:

Try to take this medicine with or just after, a meal or snack and stick to
simple meals and do not eat oil rich or spicy food. Consult your doctor if your
symptom does not improve.

Dizziness:

Lie down until dizziness passes away and then move slowly and carefully. Take
plenty amount of rest and drink plenty of fluids. Consult your doctor if your
symptom worsens.

Headache:

Apply hot or cold-water bag on your head. Try taking rest in a quiet and dark
room. Drink tea or coffee. Consult your doctor if your symptom worsens.

Tiredness:

Drink plenty of fluid and eat balanced diet and frequent meals. Do regular
minimal exercise and follow regular sleep schedule. Consult your doctor if your
symptom does not improve.

Warning & Precautions

!### Pregnancy

CARDIOPRIL H 2.5MG TABLET is not recommended for use during pregnancy, as it may
cause serious harm to the baby. Consult your doctor for advice before taking
CARDIOPRIL H 2.5MG TABLET.

!### Breastfeeding

CARDIOPRIL H 2.5MG TABLET is not recommended for use in breast-feeding women.
Consult your doctor for advice before taking CARDIOPRIL H 2.5MG TABLET.

!### Driving and Using Machines

Do not drive or operate any machines if you experience light-headedness,
dizziness and fainting due to low blood pressure. Consult your doctor for advice
before taking CARDIOPRIL H 2.5MG TABLET.

!### Alcohol

Consum
2.5MG TABLET as it may cause dizziness, light-headedness or orthostatic
hypotension (dizziness while standing up from sitting or lying position due to
low blood pressure).

!### Kidney

CARDIOPRIL H 2.5MG TABLET is not recommended for use in patients with severe
kidney impairment, renal artery stenosis or patients undergoing dialysis.
Consult your doctor for advice before taking CARDIOPRIL H 2.5MG TABLET.

!### Liver

CARDIOPRIL H 2.5MG TABLET is not recommended for use in patients with severe
liver impairment and should be used with caution in patients with progressive
liver disease. Consult your doctor for advice before taking CARDIOPRIL H 2.5MG
TABLET.

!### Allergy

Do not take CARDIOPRIL H 2.5MG TABLET if you are allergic to Ramipril and
Hydrochlorothiazide or any other ingredients of this medicine.

!### Lungs

CARDIOPRIL H 2.5MG TABLET should be used with caution in patients with history
of bronchial asthma. Consult your doctor for advice before taking CARDIOPRIL H
2.5MG TABLET.

!### Heart Disease

CARDIOPRIL H 2.5MG TABLET is not recommended for use in patients with low or
unstable blood pressure and it should be used with caution in patients with
heart problems. Consult your doctor for advice before taking CARDIOPRIL H 2.5MG
TABLET.

Others

CARDIOPRIL H 2.5MG TABLET is not recommended for you, if you have:

• difficulty urination
• personal or family history of angioedema
• electrolyte disturbances

Before taking CARDIOPRIL H 2.5MG TABLET, inform your doctor if you have:

• diabetes
• scleroderma or systemic lupus erythematosus
• dehydration problems
• upcoming major surgery including dental surgery which requires anaesthesia for numbness or sedation
• personal or family history of skin cancer
• high levels of potassium in the blood
• acute myopia and secondary angle-closure glaucoma
• parathyroid disease
• gout or increased levels of uric acid in the blood
• raynaud’s phenomenon (condition resulting from poor circulation in the extremities, such as fingers and toes)

Use in pediatrics:

CARDIOPRIL H 2.5MG TABLET is not recommended for use in children and adolescents
less than 18 years of age. Consult with your doctor for advice before taking
CARDIOPRIL H 2.5MG TABLET.

Use in geriatrics:

CARDIOPRIL H 2.5MG TABLET should be used with caution in elderly patients above
65 years of age, usually initiating the management with the lowest effective.
Consult with your doctor for advice before taking CARDIOPRIL H 2.5MG TABLET.

Interactions

A. Drug-Drug interactions:

Before taking CARDIOPRIL H 2.5MG TABLET inform your doctor if you are taking any
of following medicines:

• indomethacin, ibuprofen, aspirin, (used to relieve pain and swelling)
• ephedrine, noradrenaline or adrenaline (used to manage low blood pressure, asthma, allergies or heart failure)
• sacubitril/valsartan (used to manage long-term heart failure)
• cyclophosphamide, methotrexate (used to manage cancer)
• ciclosporin, sirolimus, everolimus (used to manage organ rejection after transplant)
• furosemide (used to manage edema or high blood pressure)
• spironolactone, amiloride, triamterene (used to retain or increase potassium levels)
• heparin (used to manage blood clots)
• prednisolone, hydrocortisone (used to manage swelling)
• allopurinol (used to manage gout or decrease uric acid levels in blood)
• procainamide (used to manage irregular heart rate)
• temsirolimus (used to manage cancer)
• carbenoxolone (used to manage pe
• racecadotril (used to manage diarrhea)
• vildagli
• lithium (used to manage mental health problems)
• trimethoprim alone or in combination with sulfamethoxazole, co-trimoxazole (used to manage bacterial infections)
• gold (used to manage arthritis)
• phenobarbital, phenytoin, carbamazepine, topiramate (used to manage seizures)
• citalopram, escitalopram and sertraline (used to manage depression)
• morphine (used to manage severe pain)
• cholestyramine and colestipol resins (used to manage high cholesterol)
• adrenocorticotropic hormone (used to manage west syndrome)
• calcium and vitamin D supplements
• amphotericin B (used to manage fungal infections)

Overdosage:

If you or anyone else accidentally takes too much of CARDIOPRIL H 2.5MG TABLET,
consult your doctor immediately. Overdosage may cause side effects such as
electrolyte depletion, slow heart rate, increased urination, kidney failure,
muscle weakness and paralysis of intestine.

Synopsis

Drug	:	Ramipril, Hydrochlorothiazide
Pharmacological Category	:	Angiotensin-II converting enzyme inhibitors, Diuretics
Therapeutic Indication	:	Hypertension
Dosage Forms	:	Tablet, Capsule

More Information

• Keep CARDIOPRIL H 2.5MG TABLET out of reach to children
• Store at normal room temperature

FAQs About CARDIOPRIL H 2.5MG TABLET

Does CARDIOPRIL H 2.5MG TABLET increases urination?

Yes, CARDIOPRIL H 2.5MG TABLET contains hydrochlorothiazide a diuretic agent
which works by removing excess fluid from the body through kidneys which leads
to increased passage of urination. Excess water loss in body may result in
dehydration. During management with CARDIOPRIL H 2.5MG TABLET if you are always
feeling tired, thirsty or you have muscle cramps constantly, immediately consult
your doctor for advice.

What to do If I forget to take CARDIOPRIL H 2.5MG TABLET?

You should take CARDIOPRIL H 2.5MG TABLET immediately when you remember. If it
is time for your next dose skip the dose and follow your regular dose schedule.
Do not double the dose to match up your missed dose.

Can CARDIOPRIL H 2.5MG TABLET cause kidney problems?

Yes, CARDIOPRIL H 2.5MG TABLET can cause kidney problems such as decreased
urination, kidney failure, progressive azotemia (high levels of nitrogen in the
blood). Your doctor may closely monitor your kidney function before and during
management with CARDIOPRIL H 2.5MG TABLET.

Does CARDIOPRIL H 2.5MG TABLET cause blood related problems?

Yes, CARDIOPRIL H 2.5MG TABLET may cause reduction in white blood cell count.
Your doctor may monitor white blood cells in the initial phase of the management
or in patients with impaired kidney function. If you have any signs or symptoms
of infection such as fever, chills, cough, body pain, tiredness during
management with CARDIOPRIL H 2.5MG TABLET, your doctor immediately.

Can CARDIOPRIL H 2.5MG TABLET taken during pregnancy?

No, CARDIOPRIL H 2.5MG TABLET is not recommended for use in pregnancy as it may
cause serious harm to the baby. If you are women of childbearing potential,
follow effective method of birth control to manage pregnancy while taking
CARDIOPRIL H 2.5MG TABLET.

Useful Diagnostic Tests

• Kidney Function Test