ATROTAS Injection 1ml

Introduction About ATROTAS INJECTION

ATROTAS INJECTION contains Atropine which belongs to the group of medicines
called Anti-cholinergic drugs. It is used to restore normal heartbeat during an
event of cardiac arrest (heart stops working suddenly). It is often used as a
preanesthetic medication to manage the risk of sudden decrease in heartbeat and
to reduce saliva secretions during surgical procedures. It can also be used in
the poisoning caused due to certain substances like insecticides or mushrooms.
It is used in combination with other medicines to reverse the effects of certain
muscle relaxants (like vecuronium, rocuronium) given during surgery. It can also
reduce the overactivity of certain medicines (muscle relaxants) used in the
management of severe muscle disorders like myasthenia gravis.

Atropine is an antimuscarinic agent. It works by blocking the effects of a
neurotransmitter called acetylcholine, which is responsible for causing
contraction of muscles, increase in body secretions, and decrease in heart rate.
As a result, it leads to stimulation of muscles, increase in heart rate, and
decrease in body secretions.

ATROTAS INJECTION is not recommended for use in patients suffering from
closed-angle glaucoma (increased eye pressure), an enlarged prostate, myasthenia
gravis, or any obstruction of gut. If you are pregnant or breastfeeding, consult
your doctor for advice before receiving ATROTAS INJECTION. The most common side
effects of ATROTAS INJECTION are dry mouth, reduced sweating, blurred vision,
constipation, increased heart rate and confusion. Consult your doctor if any of
the symptom worsens.

Uses Of ATROTAS INJECTION

It is used:

• To restore normal heartbeat during emergency conditions like cardiac arrest
• As a preanesthetic medication to reduce salivary secretions
• To reverse the effect of muscle relaxants given during surgery
• To reduce the overactivity of certain medicines used to manage severe muscle disorders like myasthenia gravis
• As an antidote for insecticides and mushroom poisoning

How ATROTAS INJECTION Works

ATROTAS INJECTION is an antimuscarinic agent. It effectively restores cardiac
activity and body function by blocking the effects of a neurotransmitter called
acetylcholine in the body which is responsible for various physiological
functions (such as contraction of skeletal or smooth muscles, increase in body
secretions or bowel movements, and decrease in heart rate). As a result, ATROTAS
INJECTION stimulates skeletal muscles, increases heart rate and reduces body
secretions (such saliva, sweat, bronchial and intestinal secretion) and bowel
movements. This helps in restoring cardiac activity during fatal conditions like
cardiac arrest or poisoning, reduces salivary secretion during surgical
procedures and stimulates muscle movements by counteracting the effects of
muscle relaxants.

How to use ATROTAS INJECTION

ATROTAS INJECTION will be given to you only by a doctor or a nurse either into
the vein (intravenously), muscle (intramuscularly), under the skin
(subcutaneously) or into the trachea (via endotracheal tube). Your doctor will
decide the correct dose and duration for you depending upon your age, body
weight, and disease condition.

Side Effects Of ATROTAS INJECTION

Common

• Dryness of mouth
• Blurred vision
• Inability to tolerate light (photophobia)
• Rapid heartbeat
• Flushing
• Constipation
• Difficulty with urination
• Decreased sweating

Rare

• Delirium (confused thinking and reduced awareness of surroundings)

Consult your doctor if you experience any of the following side effects:

• Signs of allergic reaction (such as skin rash, itching, blistering, and peeling of skin, swelling of the eyelids, face or lips, sudden wheeziness, or difficulty in breathing)

How To Manage Side Effects

Constipation

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and
drink plenty of water. Try to exercise more regularly. If you still feel
constipated, consult your doctor for advice.

!### Dry Mouth

Drink plenty of water and fruit juices. Consume soft foods with higher water and
fiber content. Artificial saliva can also be used in case of extreme dryness of
mouth. Consult your doctor if you experience dryness of mouth for prolonged
period.

Warning & Precautions

!### Pregnancy

Monitoring requiredATROTAS INJECTION should not be used in pregnant women only if it is clearly
necessary by your doctor. Your doctor will prescribe ATROTAS INJECTION only if
the benefits are greater than any possible risk to the unborn baby. Therefore,
consult your doctor before receiving.

!### Breastfeeding

Monitoring requiredATROTAS INJECTION should be used in breastfeeding mothers only if it is clearly
necessary by your doctor. Your doctor will prescribe ATROTAS INJECTION only if
the benefits are greater than any possible risk to the breastfeeding infant.
Therefore, consult your doctor before receiving.

!### Driving and Using Machines

Use with CautionDo not drive or operate any machines if your ability is affected by ATROTAS
INJECTION.

!### Alcohol

Consult your doctorAvoid consum
increase dizziness and drowsiness.

!### Kidney

Use with CautionATROTAS INJECTION should be used with caution in patients with kidney diseases.
Consult your doctor before receiving.

!### Liver

Use with CautionATROTAS INJECTION should be used with caution in patients with liver diseases.
Consult your doctor before receiving.

!### Allergy

ContraindicatedDo not receive ATROTAS INJECTION if you are allergic to Atropine.

!### Lungs

Use with CautionATROTAS INJECTION should be taken with caution in patients having chronic
pulmonary disease (airflow to the lungs becomes restricted leading to cough and
breathlessness). Therefore, consult your doctor before receiving it.

!### Heart Disease

Use with CautionATROTAS INJECTION should be used with caution in patients with heart diseases
(such as high blood pressure, fast or irregular heartbeat, angina, or heart
failure) and in patients who had a heart transplantation. Consult your doctor
before receiving.

!### Use In Pediatrics

Use with CautionATROTAS INJECTION should be used with caution in children and adolescent (below
18 years), especially if they suffer from fever or when surrounded by hot
climate. Proper dose adjustments and careful monitoring are required in such
patients, as high doses of ATROTAS INJECTION can cause CNS side effects.

!### Use In Geriatrics

Use with CautionATROTAS INJECTION should be used with caution in elderly patients (65 years and
above). Consult your doctor before receiving.

Others

ATROTAS INJECTION is not recommended for use if you:

• Have myasthenia gravis (severe muscle weakness)
• Have toxic megacolon (swollen and inflamed colon causing stomach pain, bloating and fever)
• Have reflux esophagitis (inflammation of food pipe due to reflux of stomach acid)
• Have blockade or narrowing in the gut (ex. pyloric stenosis)
• Have paralytic ileus (paralysis of intestines that causes severe constipation and bloating)
• Have glaucoma (increased pressure in the eye)
• Have enlargement of the prostate gland

Before receiving ATROTAS INJECTION, inform your doctor if you:

• Have problems in mental and physical growth (ex. down's syndrome)
• Have an overactive thyroid gland
• Have diarrhea, heart burn or indigestion
• Have nerve damage
• Have ulcers or infections in the stomach or intestines
• Have hiatus hernia (protrusion of upper part of stomach into the chest)
• Have fever

Interactions

A. Drug-Drug interactions:

Before receiving ATROTAS INJECTION, inform your doctor if you are taking any of
the following medicines such as:

• Medicines used to manage abnormal heartbeat (ex. mexiletine, digoxin, disopyramide)
• Antihistamines (used to reduce allergic reactions) ex. diphenhydramine, chlorpheniramine
• Medicines used to manage depression such as tricyclic antidepressants (ex. amitriptyline, nortriptyline, doxepin)
• Anticholinesterase (used to reduce the activity of acetylcholine) ex. neostigmine or pyridostigmine)
• Medicines used to manage mental illness (ex. chlorpromazine, promethazine, haloperidol and droperidol)
• Amantadine (used to manage parkinsonism or viral infections)
• General anesthetics (used to induce loss of consciousness or sensation before surgery) ex. propofol
• Medicines used to manage nausea and vomiting (ex. domperidone)
• Ketoconazole (used to manage fungal infections)
• Medicines that dissolve slowly in your mouth (ex. sublingual tablets, chewable tablets or throat lozenges)

Overdosage:

ATROTAS INJECTION will be administered to you only by a doctor or a nurse in a
hospital, and so it is unlikely to receive an overdose. However, consult your
doctor or nurse if you experience any unpleasant symptoms such as dry mouth or
burning sensation in mouth, difficulty in swallowing, nausea, vomiting, skin
rash, dry or red skin, feeling sleepy, intolerance of light, high body
temperature, high blood pressure, irregular heart rate, breathing difficulties,
restlessness, hallucinations, severe confusion, excitement (delirium), or
convulsions.

Synopsis

Drug	:	Atropine
Pharmacological Category	:	Muscarinic Receptor Antagonists
Therapeutic Indication	:	Restores heartbeat, reduces body secretions Manages Bradycardia, Stimulates muscle function Used in poisoning conditions
Dosage Forms	:	Eye Drops, Eye Ointment, Injection

More Information

Storage

• Keep ATROTAS INJECTION out of the sight and reach of children
• Store at room temperature

FAQs About ATROTAS INJECTION

Q: Can ATROTAS INJECTION be used for emergency conditions?

A: Yes. [GBNKEYWORD can be used during emergency conditions like cardiac arrest
to restore normal heartbeat. It can also use to manage poisoning caused due to
insecticides or mushrooms.

Q: What precautions do I need to follow while taking ATROTAS INJECTION?

A: Patients receiving ATROTAS INJECTION must inform their doctor about their
pre-existing disease conditions such as high blood pressure, coronary artery
disease, angina, chronic heart failure glaucoma, inflammation of the stomach and
intestines or blockade in the gut. Drink plenty of water or fluid after
receiving ATROTAS INJECTION, as it may lead to increased dryness of mouth. Avoid
concomitant use of other heart medicines with ATROTAS INJECTION without
consulting your as it may increase the risk of side effects.

Q: Can ATROTAS INJECTION be given via tracheal route?

A: Yes. ATROTAS INJECTION can be given into the trachea (via an endotracheal
tube) if necessary. It must be administrated only the doctor or nurse and cannot
be self-administered. Your doctor will decide the correct dose and suitable
route of administration for you depending upon the severity of your condition.

Q: Can ATROTAS INJECTION cause an increase in heart rate?

A: Yes. ATROTAS INJECTION is known to increase heart rate and is used to restore
your heart rate during emergency conditions like cardiac failure. ATROTAS
INJECTION should be used with caution in patients with high blood pressure,
coronary artery disease, and angina. Consult your doctor before receiving.

Q: Can ATROTAS INJECTION cause high blood pressure?

A: Yes. ATROTAS INJECTION restores normal heartbeat by increasing the blood
pressure and so, it must be used with caution among patients having heart
diseases like high blood pressure, chest pain or heart attack. Consult your
doctor before receiving.

Q: Can ATROTAS INJECTION be used on infants?

A: ATROTAS INJECTION is generally not recommended for use in very young
children. Your doctor might suggest a low dose depending upon the child’s age
and body weight. Therefore, consult your doctor for advice.

Q: Can ATROTAS INJECTION cause dry skin?

A: Yes. ATROTAS INJECTION can cause dry skin in some individuals. It is caused
due to decreased secretion of sweat (anhidrosis). Patients who received ATROTAS
INJECTION are advised to keep their skin hydrated always. Apply moisturizer
generously to affected dry areas of the skin. Drink plenty of water to keep
yourself hydrated. Consult your doctor for advice if you experience excessive
skin dryness.

Q: Does ATROTAS INJECTION make your mouth dry?

A: Yes. ATROTAS INJECTION can cause dry mouth in some individuals. Drink plenty
of water and fruit juices. Consume soft foods with higher water and fiber
content. Artificial saliva can also be used in case of extreme dryness of mouth.
Consult your doctor if you experience dryness of mouth for prolonged period.

Useful Diagnostic Tests

• Healthy Midlife Checkup
• Full Body Checkup-Gold